Patents Represented by Law Firm Cooley Godward Castro Huddleson & Tatum
  • Patent number: 5399464
    Abstract: A stripping composition for removing positive organic photoresist from a substrate, such as a semiconductor wafer, contains a triamine, such as diethylene triamine, and a nonpolar or polar organic solvent, such as N-methyl pyrrolidone. This composition will remove positive photoresist from semiconductor wafers, even after ion implantation into the wafers through the positive photoresist. The wafers are immersed in the composition, for example, at a temperature of 110.degree. C. for five minutes, in an ultrasonic bath after heavy ion implantation doses through the photoresist, such as 1.times.10.sup.16 ions/cm.sup.2, for complete removal of the photoresist. Prebaking the photoresist at a temperature of between about 150.degree. and 220.degree. C. for a time of from about 15 minutes to about 30 minutes, prior to stripping the positive organic photoresist layer with the triamine, enhances the removal.
    Type: Grant
    Filed: April 6, 1992
    Date of Patent: March 21, 1995
    Assignee: EKC Technology, Inc.
    Inventor: Wai M. Lee
  • Patent number: 5395928
    Abstract: A method is provided for the preparation and/or analysis of synthetic phosphorothioate and -dithioate oligonucleotides. In particular, the method permits separation of fully sulfurized phosphorothioate or -dithioate oligonucleotides from incompletely sulfurized defect species on an anion exchange HPLC columns using concentration gradients of novel "soft base" anionic eluents, such as bromide, thiocyanate, and the like.
    Type: Grant
    Filed: May 10, 1993
    Date of Patent: March 7, 1995
    Assignee: Lynx Therapeutics, Inc.
    Inventor: B. John Bergot
  • Patent number: 5393602
    Abstract: Polymeric materials having an inverse temperature transition, particularly bioelastic polymers comprising monomeric units selected from the group consisting of bioelastic pentapeptides, tetrapeptides, and nonapeptides, have been found to have controllable absorbent properties that can be varied with temperature or contact with liquids. The materials are selected to be in a contracted or swollen state initially, depending on the specific use. When the material is located under different conditions (such as a different temperature resulting from being either in contact with or at distance from human skin), the material undergoes swelling or contraction to switch to the other state.
    Type: Grant
    Filed: April 19, 1991
    Date of Patent: February 28, 1995
    Assignees: Bioelastics Research Ltd., UAB Research Foundation
    Inventor: Dan W. Urry
  • Patent number: 5393427
    Abstract: A process and installation for the removal of organic matter, phosphate ions and nitrogenous compounds from sewage wastewater. The installation comprises a raw sewage feed line 12 shown feeding into a primary separation basin 14. The primary separation basin 14 has an overflow flow line 16, discharging separated effluent to an attached growth fermentation vessel or fermenter 18. The fermenter 18 is filled with solid supports 20 with sufficient voids therebetween to allow the effluent to pass through the supports 20 and to allow for the growth of fermenting bacteria (not shown) on the supports 20. The supports 20 are shown diagrammatically in the drawings, and can be in the form of rotating discs, hanging or suspended ropes which move as the liquid is passed through the system, a fluidized bed in which the solids are kept in suspension by upward movement of the liquid, rings, slats or plates. The liquid effluent then passes out of the fermenter 18, through flow line 26, for further processing.
    Type: Grant
    Filed: April 8, 1993
    Date of Patent: February 28, 1995
    Inventor: James L. Barnard
  • Patent number: 5370135
    Abstract: A method of monitoring tocolytic therapy, which comprises determining a first concentration of estriol in a body fluid of a pregnant patient undergoing or diagnosed as a candidate for undergoing treatment with a tocolytic agent and, based on the value of the first concentration relative to a standard, either initiating, continuing, discontinuing, or modifying the treatment.
    Type: Grant
    Filed: October 13, 1993
    Date of Patent: December 6, 1994
    Assignee: Biex, Inc.
    Inventor: Vivian K. Dullien
  • Patent number: 5367823
    Abstract: An improved cut flower storage and display assembly is provided having a plurality of vertically spaced storage and display containers and including integral container dividers formed by the configuration of the vertically spaced containers. The assembly includes a liquid circulation system formed by discharge apertures in upper containers, a removable pump in a lowest one of the containers and a flexible liquid line connected between the pump and an uppermost container. The liquid circulation system permits easy removal of a container needing cleaning and replacement of the container needing cleaning with a clean container, so that the container needing cleaning can be cleaned remote from the apparatus.
    Type: Grant
    Filed: August 31, 1993
    Date of Patent: November 29, 1994
    Inventor: John Ferris
  • Patent number: 5362625
    Abstract: The use of omega-acceptor and omega-donor polypeptides (comprising about two-thirds and one-third of the .beta.-galactosidase molecule amino and carboxyl termini, respectively), prepared by recombinant DNA techniques, DNA synthesis, or chemical polypeptide synthesis techniques, which are capable of interacting to form an active enzyme complex having catalytic activity characteristic of .beta.-galactosidase, is described along with improved methods and novel compositions for enzyme complementation assays for qualitative and quantitative determination of a suspected analyte in a sample.
    Type: Grant
    Filed: May 25, 1993
    Date of Patent: November 8, 1994
    Assignee: Microgenics Corporation
    Inventors: Mark Krevolin, David Kates
  • Patent number: 5344783
    Abstract: An assay for screening snake venom for the presence or absence of platelet aggregation inhibitors (PAIs) based on specific receptor binding is described. Using this assay, the identification and characterization of the PAI in a wide range of snake venom samples were accomplished. The purified PAI from several of these active snake venoms is described. In addition, PAIs lacking the Arg-Gly-Asp adhesion sequence but containing Lys-Gly-Asp are prepared and shown to specifically inhibit the binding of fibrinogen or von Willebrand Factor to GP IIb-IIIa.
    Type: Grant
    Filed: July 12, 1993
    Date of Patent: September 6, 1994
    Assignee: COR Therapeutics, Inc.
    Inventors: Robert M. Scarborough, Israel F. Charo
  • Patent number: 5343875
    Abstract: A protective device to protect against needle stick injuries in health care. The device has a base. There are troughs in the base to receive and protect fingers. Each trough has an inner wall that, with the other inner side wall defines a retaining passage between the troughs and on its inner surface a grip for the fingers. The device may also be able to hold a sample tube and include an indent adjacent one edge to place over a subcutaneous implanted injection port.
    Type: Grant
    Filed: September 28, 1992
    Date of Patent: September 6, 1994
    Assignee: Superior Diapering Products Ltd.
    Inventor: Marjorie L. Chase
  • Patent number: 5336256
    Abstract: A vascular prosthetic material having at least one layer containing an elastomeric material capable of reversibly contracting and relaxing by an inverse temperature transition.The vascular prosthetic material matches the compliance and elasticity of vessels replaced, and is biocompatible and biodegradable. The material may also have incorporated therein chemotactic peptides and cell attachment sequences.
    Type: Grant
    Filed: April 22, 1988
    Date of Patent: August 9, 1994
    Assignee: UAB Research Foundation
    Inventor: Dan W. Urry
  • Patent number: 5330141
    Abstract: A garment bag luggage cart attachment (10) fastens to a conventional soft-sided garment bag (12), which folds along spine (14) and has a handle (16) midway along the spine (14). Attachment (10) is formed from a first frame member (18) and a second frame member (20) pivotally connected to the first frame member (18) at (22) and (24). A flexible fabric belt (42) is permanently attached at one end to raised central portion (26) on the first frame member (18) and is releasably attached around raised central portion (30) on the second frame member (20) by means of Velcro type fasteners at (44). A set of short straps (46) are fastened to bottoms (28) and (32) of the first and second frame members (18) and (20). Straps (48) are fastened to strap rings (36) at ends (38) and (40). The straps (48) are double layered, with layers (50) and (52) free to separate along either side of the garment bag (12).
    Type: Grant
    Filed: May 29, 1992
    Date of Patent: July 19, 1994
    Assignee: Inno Design, Inc.
    Inventor: Young S. Kim
  • Patent number: 5318899
    Abstract: An assay for screening snake venom for the presence or absence of platelet aggregation inhibitors (PAIs) based on specific receptor binding is described. Using this assay, the identification and characterization of PAIs in a wide range of snake venom samples was accomplished. The isolated and purified PAI from several of these active snake venoms is described and characterized. In addition, PAIs lacking the Arg-Gly-Asp (RGD) adhesion sequence but containing K.sup.* -(G/Sar)-D wherein K.sup.* is a modified lysyl residue of the formulaR.sup.1.sub.2 N(CH.sub.2).sub.4 CHNHCO--wherein each R.sup.1 is independently H, alkyl(1-6C) or at most one R.sup.1 is R.sup.2 --C.dbd.NR.sup.3 wherein R.sup.2 is H, alkyl(1-6C) or is NR.sup.4.sub.2 in which each R.sup.4 is independently H or alkyl(1-6C) and R.sup.3 is H, alkyl(1-6C), phenyl or benzyl, or R.sup.2 --C=NR.sup.3 is a radical selected from the group consisting of: ##STR1## where m is an integer of 2-3, and each R.sup.
    Type: Grant
    Filed: February 20, 1990
    Date of Patent: June 7, 1994
    Assignee: COR Therapeutics, Inc.
    Inventors: Robert M. Scarborough, David L. Wolf, Israel F. Charo
  • Patent number: 5305221
    Abstract: This process models production integrated processing equipment, also known as cluster tools, modular equipment, track systems, etc. Further, the model produced by this invention is a real-world model, i.e., it is realistic and validatable. In addition, the invention provides a process for developing machine-specific implementations for PIPEs performing such complex processes as plasma etching, plasma deposition, chemical-vapor deposition, physical-vapor deposition, photolithography, photo-resist processing, rapid thermal processing, and oxidation, as well as other processes. The PIPE-specific model can be used for performance analysis. The effect of changes in process times, process recipes, and process mixtures on cycle time, throughput, resource utilization, and bottlenecks can be analyzed. These PIPE models may be used in the design or redesign of PIPEs. Further, the PIPE-specific model can be used to control material movement in the PIPE, including buffer dynamics to avoid machine lock-up.
    Type: Grant
    Filed: May 4, 1990
    Date of Patent: April 19, 1994
    Inventor: Robert W. Atherton
  • Patent number: 5304672
    Abstract: A method for the preparation of compounds of the formula ##STR1## wherein X represents a group of the formula OR.sub.1 or NR.sub.1 R.sub.2, wherein R.sub.1 and R.sub.2 independently represent H or an organic group that forms a stable covalent bond with the N or 0 of said X; Y is H or an organic group that forms a stable ester with the adjacent COO group; R is an alkyl or aryl group optionally substituted with one or more stable organic substituents; each R.sub.3 independently represents a stable organic group; and n is an integer from 0 to 3;the method using new intermediates of the formula ##STR2## wherein R.sub.3 and Y have the foregoing meanings;W is either F or Cl; andR.sub.9 is a hydrocarbon such as a C.sub.1 -C.sub.4 alkyl or alkenyl group.
    Type: Grant
    Filed: November 9, 1992
    Date of Patent: April 19, 1994
    Assignees: Orsan, Orsem
    Inventors: Jeffrey Labovitz, William J. Guilford, Lawrence Fang, Yi Liang
  • Patent number: 5299632
    Abstract: A fin device includes a plate having a bottom surface for contacting an upper surface of an integrated circuit and an upper surface from which two opposite end walls extend upward. A plurality of rows of fins extend between the opposite end walls and extend upward from the upper surface of the plate. A substantially L-shaped member extends outward and upward from each fin of first and last rows which are adjacent to and extend parallel to the opposite end walls. Each L-shaped member extends to a height above the fins. The fins of the first and last rows respectively define a groove with associated adjacent end walls for receiving at least one snapping fastener. Each snapping fastener is substantially T-shaped, including a substantially inverted L-shaped portion with a distal snapping head at an end thereof and two arms extending laterally from the other end thereof. The arms have a recessed portion at an underside thereof.
    Type: Grant
    Filed: February 19, 1993
    Date of Patent: April 5, 1994
    Inventor: Lien-Jung Lee
  • Patent number: 5300779
    Abstract: Novel methods and devices are provided involving at least one chamber, at least one capillary, and at least one reagent involved in a system providing for a detectable signal. As appropriate, the devices provide for measuring a sample, mixing the sample with reagents, defining a flow path, and reading the result. Of particular interest is the use of combinations of specific binding pair members which result in agglutination information, where the resulting agglutination particles may provide for changes in flow rate, light patterns of a flowing medium, or light absorption or scattering. A fabrication technique particularly suited for forming internal chambers in plastic devices is also described along with various control devices for use with the basic device.
    Type: Grant
    Filed: August 18, 1992
    Date of Patent: April 5, 1994
    Assignee: Biotrack, Inc.
    Inventors: Robert S. Hillman, Michael E. Cobb, Jimmy D. Allen, Ian Gibbons, Vladimir E. Ostoich, Laura J. Winfrey
  • Patent number: 5300496
    Abstract: A pharmaceutical composition useful for lowering blood sugar and suppressing appetite in mammals. The composition comprises compounds of a formula selected from VOL.sub.2 or VO(OR)L.sub.2 in which L is a bidentate monoprotic ligand and R is an organic group. The composition includes a pharmaceutically acceptable carrier. The invention also provides a method of lowering blood sugar and suppressing appetite in a mammal that comprises administering to the mammal a compound of the above formula.
    Type: Grant
    Filed: September 30, 1991
    Date of Patent: April 5, 1994
    Assignee: The University of British Columbia
    Inventors: John H. McNeill, Hamid R. Hoveyda, Chris Orvig
  • Patent number: D347067
    Type: Grant
    Filed: March 15, 1991
    Date of Patent: May 17, 1994
    Assignee: Biotrack, Inc.
    Inventors: Robert Shartle, William Aldrich
  • Patent number: D356601
    Type: Grant
    Filed: November 18, 1991
    Date of Patent: March 21, 1995
    Assignee: Verifone, Inc.
    Inventors: James S. Arakaki, Allan Avnet, J. Mark Stanton
  • Patent number: D357219
    Type: Grant
    Filed: August 31, 1993
    Date of Patent: April 11, 1995
    Assignee: Flower Environments, Inc.
    Inventor: John Ferris