Patents Represented by Attorney Cooper & Dunham LLP
  • Patent number: 8227379
    Abstract: The present invention provides a thermosensitive recording medium including a white plastic support, a thermosensitive recording layer containing a binder resin as a binding agent, a colorless or pale color leuco dye and a color developer for heat-developing the leuco dye, a protective layer, and a back layer containing an electron-conductive needle filler and an ion-conductive polymer, wherein the thermosensitive recording layer is disposed on the white plastic support, the protective layer is disposed on the thermosensitive recording layer, and the back layer is disposed on a side of the white plastic support opposite to the side where the thermosensitive recording layer is disposed.
    Type: Grant
    Filed: February 20, 2009
    Date of Patent: July 24, 2012
    Assignee: Ricoh Company, Ltd.
    Inventors: Shinji Okada, Hiroshi Tohmatsu, Hideo Aihara, Hirokazu Watari
  • Patent number: 8227473
    Abstract: This invention provides compounds having the structure which may be used for the treatment of tumors.
    Type: Grant
    Filed: July 17, 2009
    Date of Patent: July 24, 2012
    Assignee: Lixte Biotechnology, Inc.
    Inventors: John S. Kovach, Francis Johnson
  • Patent number: 8222942
    Abstract: An initialization circuit comprises a section signal generator generating a section signal, of which a prescribed section is enabled in response to a power-up signal, a first oscillator generating a first period signal in response to the section signal, a first period multiplier generating a first multiplied signal by multiplying a period of the first period signal, and a signal selector transferring the first multiplied signal or a second multiplied signal selectively as a self-refresh enable signal in response to the section signal.
    Type: Grant
    Filed: June 3, 2009
    Date of Patent: July 17, 2012
    Assignee: Hynix Semiconductor Inc.
    Inventor: Jong Won Lee
  • Patent number: 8220998
    Abstract: The invention relates to a fluid dynamic bearing system having a stationary bearing component and a moving bearing component, that are separated from one another by a bearing gap filled with a bearing fluid. There are two radial bearing regions separated from one another and marked by radial bearing grooves. A separator region having a larger bearing gap width is disposed between the radial bearing regions. The radial bearing grooves of the two radial bearing regions have inner ends facing each other and outer ends facing away from each other. At least the outer ends of the radial bearing grooves are connected to each other by connecting grooves. According to the invention, wear zones provided especially for this purpose are disposed adjoining the connecting grooves, so as to prevent material wear at other regions of the bearing.
    Type: Grant
    Filed: April 23, 2010
    Date of Patent: July 17, 2012
    Assignee: Minebea Co., Ltd.
    Inventor: Olaf Winterhalter
  • Patent number: 8216607
    Abstract: This invention provides a method for increasing apoptosis in a cancer cell comprising contacting the cancer cell with (a) gemcitabine and (b) C6-ceramide, sequentially or concomitantly, wherein the gemcitabine and C6-ceramide are in amounts such that the apoptosis induced by the combination of gemcitabine and C6-ceramide is greater than the apoptosis induced by contacting the cancer cell with either gemcitabine alone or C6-ceramide alone. This invention also provides a method of decreasing the size of a tumor, which method comprises contacting the tumor with (a) gemcitabine and (b) C6-ceramide, sequentially or concomitantly, wherein the gemcitabine and C6-ceramide are in amounts such that the decrease in tumor size induced by the combination of gemcitabine and C6-ceramide is greater than the decrease in tumor size induced by contacting the tumor with either gemcitabine alone or C6-ceramide alone.
    Type: Grant
    Filed: March 17, 2009
    Date of Patent: July 10, 2012
    Assignee: Roger Williams Hospital
    Inventor: Harold J. Wanebo
  • Patent number: 8217633
    Abstract: A switching regulator is provided that includes a step-down circuit configured to output a voltage lower than an input voltage, a step-up circuit configured to output a voltage higher than the input voltage, and a control unit having a voltage detector configured to detect an output voltage and being configured to prohibit operation of the step-up circuit until the output voltage rises to a first voltage lower than the input voltage.
    Type: Grant
    Filed: May 23, 2007
    Date of Patent: July 10, 2012
    Assignee: Ricoh Company, Ltd.
    Inventor: Shinya Shimizu
  • Patent number: 8218730
    Abstract: A mechanism to which a liquid-repellent structure hard to be exfoliated is applied. The tip of each of microprojections has a generally spherical surface. When a liquid metal (8) comes into contact with such a surface, the liquid metal (8) cannot enter the spaces among microprojections and is supported by the surfaces of the tips only with point contact. Therefore, the liquid metal (8) neither wets the surface of the base material nor spread over the surface. The liquid-repellent surface (11) has a structure such that the liquid metal (8) is supported by point contact of the many microprojections and repelled by the surface (11), and does not wet the surface (11).
    Type: Grant
    Filed: June 12, 2008
    Date of Patent: July 10, 2012
    Assignee: Hitachi Medical Corporation
    Inventor: Hidefumi Okamura
  • Patent number: 8215451
    Abstract: [Subject] The subject of the present invention is to provide a shock and sound absorbing material having a light weight, and demonstrating an excellent shock and sound absorbing performance. As a method for solving the subject, the present invention provides a shock and sound absorbing material 1 comprising a porous component 2, and a surface material 3 which is laminated onto the porous component 2, wherein the surface material 3 has at least one layer made of a stretchable paper material 5. The shock and sound absorbing material 1 is installed on a cover panel 7 covering a sound source such as an engine cover, and the porous component 2 is set so as to face the cover panel 7, with the surface material 3 being set so as to face the sound source, and form a cell structure between the cover panel 7 and the surface material 3.
    Type: Grant
    Filed: June 1, 2009
    Date of Patent: July 10, 2012
    Assignee: Nagoya Oilchemical Co., Ltd.
    Inventors: Yasuhiko Nishimura, Masanori Ogawa, Makoto Fujii, Naohiro Mizutani
  • Patent number: 8217491
    Abstract: A semiconductor device includes a base insulating film on which a silicon fuse, silicon wiring patterns, and a silicon guard ring are formed. The silicon guard ring surrounds the silicon fuse and has silicon cutout parts so as not to contact the silicon wiring patterns. A via guard ring, which has via cutout parts located above the silicon cutout parts, is formed in an interlayer insulating film and on the silicon guard ring. A metal wiring guard ring is formed on the via guard ring and the interlayer insulating film. A silicon nitride film is formed on the interlayer insulating film so as to cover the metal wiring guard ring. An interface between the interlayer insulating film and the metal wiring guard ring at the via cutout parts is covered by the silicon nitride film.
    Type: Grant
    Filed: September 23, 2010
    Date of Patent: July 10, 2012
    Assignee: Ricoh Company, Ltd.
    Inventors: Masashi Oshima, Masaya Ohtsuka
  • Patent number: 8212282
    Abstract: A power supply device is disclosed that is able to satisfy the power requirements of a device in service and has high efficiency. The power supply device includes a first power supply; a voltage step-up unit that steps up an output voltage of the first power supply; a voltage step-down unit that steps down an output voltage of the voltage step-up unit; and a load that is driven to operate by an output voltage of the voltage step-down unit. The voltage step-up unit steps up the output voltage of the first power supply to a lower limit of an operating voltage of the voltage step-down unit.
    Type: Grant
    Filed: September 24, 2010
    Date of Patent: July 3, 2012
    Assignee: Ricoh Company, Ltd.
    Inventors: Masaya Ohtsuka, Yoshinori Ueda
  • Patent number: 8212609
    Abstract: An internal voltage generation circuit includes a first enable signal generator configured to delay an active signal to generate a first enable signal, a comparison signal generator configured to compare the internal voltage with an internal reference voltage to generate a comparison signal, a pulse signal generator configured to receive the first enable signal and to generate a pulse signal, a transmission device configured to buffer and transfer the comparison signal as a pull-down signal, and a drive device configured to drive the driving signal to the first level in response to the pull-down signal.
    Type: Grant
    Filed: August 30, 2011
    Date of Patent: July 3, 2012
    Assignee: Hynix Semiconductor Inc.
    Inventor: Ho Uk Song
  • Patent number: 8212003
    Abstract: This application relates to a fusion protein, which is composed of a thrombolytic protein, an anticoagulant protein, and a linker peptide. In particular, the fusion protein is composed of an anticoagulant protein and a protein molecule having plasminogen-activating activity, wherein said two proteins are linked together via a linker peptide, which can be recognized and cleaved by blood coagulation factors. The application also relates to the medical use of said fusion protein, and to the use of the linker peptide which can be recognized by blood coagulation factor in linking a thrombolytic protein and an anticoagulation protein.
    Type: Grant
    Filed: September 3, 2003
    Date of Patent: July 3, 2012
    Assignee: Institute of Radiation Medicine, Academy of Military Medical Sciences, PLA
    Inventors: Bingxing Shi, Zuze Wu, Aiping Yu, Chunna Dong
  • Patent number: 8211852
    Abstract: Soluble molecules are provided. Thus, for example, provided is a soluble molecule which comprises a heterologous amino acid sequence conjugated to a CCR5 amino acid sequence being capable of binding a CCR5 ligand, and wherein the molecule is devoid of an N-terminus domain of CCR5. Also provided are pharmaceutical compositions which comprise the above molecules and methods and uses of same.
    Type: Grant
    Filed: February 18, 2007
    Date of Patent: July 3, 2012
    Assignee: Rappaport Family Institute for Research in the Medical Sciences
    Inventors: Nathan Karin, Gizi Wildbaum
  • Patent number: 8212598
    Abstract: An oscillation frequency control circuit controls a second oscillation circuit, which generates and outputs a second clock signal of a second frequency according to a received control signal, to control the second frequency. The oscillation frequency control circuit includes a frequency difference detection circuit unit configured to detect a difference between a predetermined first frequency of a first clock signal generated by an external first oscillation circuit and the second frequency, and generate and output an output signal indicating a detection result, and a frequency control circuit unit configured to control, according to the output signal of the frequency difference detection circuit unit, the second oscillation circuit to control the second frequency of the second clock signal to make an absolute value of the difference between the first frequency and the second frequency greater than a predetermined value.
    Type: Grant
    Filed: December 5, 2008
    Date of Patent: July 3, 2012
    Assignee: Ricoh Company, Ltd.
    Inventor: Takashi Michiyoshi
  • Patent number: 8210236
    Abstract: Exemplary embodiments of the invention provide a method of measuring the separation of moving confronting casting surfaces within a casting cavity of a casting apparatus. The method involves attaching at least one separation sensing device to a first one of a pair of confronting casting surfaces outside the casting cavity and then moving the casting surfaces to advance the sensing device(s) through the casting cavity while operating the device(s) to generate signals. The signals are monitored continuously or at regular intervals and converted to distance measurements representing separation of the surfaces at a plurality of positions through the casting cavity. Other exemplary embodiments provide apparatus for carrying out the method, and methods of measuring irregularities of casting belts or the like.
    Type: Grant
    Filed: June 7, 2010
    Date of Patent: July 3, 2012
    Assignee: Novelis Inc.
    Inventor: Daniel Godin
  • Patent number: 8211853
    Abstract: Disclosed is a method of reducing the amount of adipose tissue in a subject comprising administering to the subject an amount of an sFRP-5 peptide effective to reduce the amount of adipose tissue, or an amount of a molecule effective to stimulate expression of the sFRP-5 peptide in the subject. Also disclosed is a screen for molecules that can reduce the amount of adipose tissue in a subject.
    Type: Grant
    Filed: July 9, 2010
    Date of Patent: July 3, 2012
    Assignee: HMGene Inc.
    Inventors: Kiran K. Chada, Roland Chouinard, Hena Ashar, Md. Abu Sayed
  • Patent number: 8212444
    Abstract: The invention relates to a magnetic axial bearing for taking up axial forces that act on a rotor component that is rotatably supported about a rotational axis with respect to a stator component. The bearing comprises a first bearing part consisting of at least one permanent magnet and at least two flux guide elements associated with the permanent magnet that are disposed on opposing end faces of the permanent magnet and aligned substantially radial and perpendicular to the rotational axis, and a second bearing part consisting of at least two flux guide elements that are disposed at a mutual spacing to one another and aligned substantially radial and perpendicular to the rotational axis, each flux guide element of the second bearing part being associated with a flux guide element of the first bearing part and lying directly opposite the latter in a radial direction and separated from it by an air gap.
    Type: Grant
    Filed: December 2, 2008
    Date of Patent: July 3, 2012
    Assignee: Minebea Co., Ltd.
    Inventors: Vladimir V. Popov, Martin Bauer, Guido Schmid, Stefan Schwamberger
  • Patent number: 8213892
    Abstract: A FM-AM demodulator includes a FM signal amplifier, a local oscillator, an image oscillator, a first selector, a first orthogonal mixer, an AM signal amplifier, a first frequency divider, a second frequency divider, a second selector, a second orthogonal mixer, a third selector, a first filter, a first amplifier, a fourth selector, a second filter, a second amplifier, a first gain controller, an I/Q compensation unit, an IF oscillator, a third orthogonal mixer, an adder, a channel filter configured to extract a signal with a predetermined frequency band output from the adder, a third amplifier, a second gain controller, a demodulator, and an I/Q compensation controller configured to generate an I/Q compensation signal to use for adjusting phase and gain of the I signal used in an I/Q compensation unit by detecting amplitude of the output signal from the demodulator, and output the generated signal to the I/Q compensation unit.
    Type: Grant
    Filed: January 12, 2010
    Date of Patent: July 3, 2012
    Assignee: Ricoh Company, Ltd.
    Inventor: Nobunari Tsukamoto
  • Patent number: 8212538
    Abstract: A switching regulator includes a switching transistor, an inductor, a feedback voltage generator, a hysteresis comparator circuit, and a feedback loop circuit. The switching transistor alternately switches on and off. The inductor charges when the switching transistor is on. The feedback voltage generator generates a first feedback voltage by dividing an output voltage. The hysteresis comparator circuit has a voltage comparator to compare the first feedback voltage against a reference voltage to output a comparator output signal as a result of the comparison. The feedback loop circuit feeds the comparator output signal back to the feedback voltage generator to generate a second feedback voltage. The first feedback voltage has an alternating current component substantially dependent on the second feedback voltage varying with the comparator output signal.
    Type: Grant
    Filed: December 2, 2009
    Date of Patent: July 3, 2012
    Assignee: Ricoh Company, Ltd.
    Inventor: Junji Nishida
  • Patent number: 8212529
    Abstract: A charge/discharge protection circuit for protecting a plurality of serially connected secondary batteries from overcharge, overdischarge, and current overflow by detecting overcharge, overdischarge, and current overflow and switching on/off a discharge controlling FET or a charge controlling FET according to the detection results is disclosed including an overcharge protecting circuit configured to prioritize the detection results corresponding to overcharge and switch off the charge controlling FET in a case where a charger is connected to the charge/discharge protection circuit.
    Type: Grant
    Filed: September 1, 2008
    Date of Patent: July 3, 2012
    Assignee: Ricoh Company, Ltd.
    Inventor: Norifumi Yamamoto