Patents Represented by Attorney David E. Brook
  • Patent number: 4060778
    Abstract: A microwave harmonic absorption filter is disclosed which has an extended single mode pass-band ranging over one or more octaves as well as enhanced attenuation in the stop-band. This filter has a primary, rectangular waveguide having one or more ridges on the inner surfaces of its elongated wall members. Secondary waveguides are provided on the outer surfaces of these wall members and these secondary waveguides serve to diminish propagation of microwave energy in the stop-band. Apertures extend through the wall members of the primary, ridged, rectangular waveguide so that microwave energy within the range of frequencies of the stop-band can be transmitted from the primary waveguide into the secondary waveguides.
    Type: Grant
    Filed: July 12, 1976
    Date of Patent: November 29, 1977
    Assignee: Microwave Research Corporation
    Inventors: Ibrahim El Hefni, Kenneth A. Green, Donald C. Cloutier
  • Patent number: 4060081
    Abstract: A multilayer membrane, which is useful as synthetic skin, is disclosed herein. A first layer is formed from a material which does not provoke an immune response and which is also insoluble and nondegradable in the presence of body fluids and/or body enzymes. Preferred materials for the first layer are crosslinked composites of collagen and a mucopolysaccharide. A second layer is formed from a nontoxic material which controls the moisture flux of the overall membrane to about 0.1 to 1 mg./cm.sup.2 /hr. Suitable materials for the second layer include synthetic polymers such as silicone resins, polyacrylate or polymethacrylate esters or their copolymers, and polyurethanes.
    Type: Grant
    Filed: July 15, 1975
    Date of Patent: November 29, 1977
    Assignee: Massachusetts Institute of Technology
    Inventors: Ioannis V. Yannas, John F. Burke, Philip L. Gordon, Chor Huang
  • Patent number: 4059108
    Abstract: A pheresis process and apparatus for carrying it out. Blood from a donor is transferred to a pheresis bowl formed to have a red cell reservoir and a plasma reservoir in fluid communication through plasma ducts. The pheresis bowl is adapted for centrifuging to separate the red cells and plasma. This separation is accomplished simultaneously with the withdrawal of blood from the donor. At the end of the withdrawal the red cells are returned to the donor. The connection with the donor is thus continuously maintained during the entire procedure. The process is safe, fast and economical.
    Type: Grant
    Filed: July 15, 1975
    Date of Patent: November 22, 1977
    Assignee: Haemonetics Corporation
    Inventor: Allen Latham, Jr.
  • Patent number: 4059461
    Abstract: A method is disclosed for improving the crystallinity of semiconductor films by scanning the surface of such films with a shaped, focused laser beam. The laser is matched to the film so that the beam delivers sufficient energy thereto to heat the film above a temperature at which crystallization occurs along the scan track.
    Type: Grant
    Filed: December 10, 1975
    Date of Patent: November 22, 1977
    Assignee: Massachusetts Institute of Technology
    Inventors: John C. C. Fan, Herbert J. Zeiger
  • Patent number: 4053319
    Abstract: A lithographic printing plate is produced by the steps of forming a latent electrostatic image on a photoconductive zinc oxide insulating layer and developing this layer with a toner which forms an imagewise deposit on the recording layer. Applicants' invention relates to contacting the portions of the recording layer which are not covered with the hydrophobic deposit with a hydrophilizing composition (commonly called a conversion wash) comprising the reaction product of (1) phosphoric acid or one of the anions derived from such acid, (2) an organic amine compound, and (3) a hydrophilic metal cation, to form a reaction product with zinc ions from the zinc oxide which reaction product of zinc ions with said composition is substantially insoluble in said composition and is preferentially wetted by water thereby repelling lithographic inks. The plate produced by this process is especially useful for use on a lithographic offset press to produce multiple copies of an original.
    Type: Grant
    Filed: August 7, 1975
    Date of Patent: October 11, 1977
    Assignee: Itek Corporation
    Inventors: Raymond R. Nadeau, John E. Wyman
  • Patent number: 4052536
    Abstract: Electrolytes are disclosed which are useful in solar energy conversion and which have a wider range of wavelength response and enhanced activity compared to the photoredox system contained therein. These electrolytes contain one or more photosensitizing dyes which luminesce within the range of wavelengths absorbed by the photoredox system.
    Type: Grant
    Filed: June 24, 1976
    Date of Patent: October 4, 1977
    Assignee: The Trustees of Boston University
    Inventors: Norman N. Lichtin, Peter D. Wildes
  • Patent number: 4046858
    Abstract: A new synthesis is disclosed which produces synthetic crystalline hydroxyapatite. The process comprises reacting anhydrous trisodium phosphate wih calcium chloride in a formamide/water solution. Good yields of hydroxyapatite are obtained quickly, simply, and at low temperatures.
    Type: Grant
    Filed: July 24, 1974
    Date of Patent: September 6, 1977
    Inventors: John J. Barsa, Edward T. Farris, Richard J. Lagow
  • Patent number: 4036693
    Abstract: A method of treating certain cell culture microcarriers to improve their performance is disclosed. In this method, positively charged microcarriers, such as those produced by reacting polydextran beads with diethylaminoethyl, are treated by contacting them with macromolecular polyanions, such as carboxymethylcellulose, prior and/or during use in cultures. Such treatment overcomes deleterious effects previously observed in attempts to use these microcarriers in cell culture systems.
    Type: Grant
    Filed: February 2, 1976
    Date of Patent: July 19, 1977
    Assignee: Massachusetts Institute of Technology
    Inventors: David W. Levine, William G. Thilly, Daniel I. C. Wang
  • Patent number: 4035330
    Abstract: A hydrophilic copolymer of an N,N-di(C.sub.1 -C.sub.2 alkyl)acrylamide is disclosed. The copolymer is formed by reacting, based on 100 parts, from about 20-80 parts of a C.sub.1 -C.sub.2 alkyl substituted acrylamide, about 10-80 parts of a C.sub.1 -C.sub.4 alkyl acrylate, methacrylate, or combinations of acrylate and methacrylate, and about 2-20 parts of a glycidyl ester of acrylic, methacrylic or crotonic acid. The resulting copolymerization product can be equilibrated with water or other aqueous solutions to form hydrogels useful in forming shaped hydrogel articles. One particular shaped article which can be formed is a hydrophilic contact lens. A process for forming the hydrogels is also disclosed.
    Type: Grant
    Filed: December 22, 1975
    Date of Patent: July 12, 1977
    Assignee: Itek Corporation
    Inventor: Herman S. Schultz
  • Patent number: 4031851
    Abstract: Fabrication apparatus is described for improving the ultimate strength of boron and other high strength filaments. In the apparatus, a gradual cooling zone is placed at the exit end of the reaction zone to prevent the sudden thermal shock normally encountered when hot boron filaments exit into the ambient atmosphere. A preheating zone can be added prior to the entrance into the reaction zone if desired. Additionally, the entrance and exit ends of the reaction zone are sealed with a molten metal, such as tin, heated to elevated temperatures close to the reaction temperature. These molten metal electrodes tend to minimize deposition of weak boron due to a low temperature region immediately following the reactor entrance and help to eliminate sudden thermal shocks to the filaments at the exit.
    Type: Grant
    Filed: April 18, 1974
    Date of Patent: June 28, 1977
    Inventor: Jose L. Camahort
  • Patent number: 4016036
    Abstract: A method is disclosed for serially culturing keratinocytes such as human epidermal cells and teratomal keratinocytes. These can be serially grown in culture to produce colonies and eventually stratified squamous epithelium by including in the culture fibroblast cells or medium harvested from fibroblast cultures. When fibroblast cells are used, they are treated to prevent their multiplication, and they are also introduced into the cultures at a controlled density.
    Type: Grant
    Filed: November 14, 1975
    Date of Patent: April 5, 1977
    Assignee: Massachusetts Institute of Technology
    Inventors: Howard Green, James G. Rheinwald
  • Patent number: 4015027
    Abstract: Method is disclosed for transferring non-fused xerographic toner images from a first support material, such as a photoconductive insulating surface, to a second support material, such as paper, and fusing the toner images to the second support material. Such method utilizes an intermediate transfer member having a smooth surface of low surface free energy and a hardness of from 3 to 70 durometers. The intermediate transfer member can be, for example, a 0.1-10 mil layer of silicone rubber coated onto a polyimide support. The member can be formed into belt or drum configuration. Toner images are transferred from the first support material to the intermediate transfer member; this can be by any conventional transfer method, but pressure transfer is preferred. Next, the toner image is heated on the intermediate transfer member to at least its melting point temperature.
    Type: Grant
    Filed: February 20, 1975
    Date of Patent: March 29, 1977
    Assignee: Itek Corporation
    Inventors: William R. Buchan, Robert A. Moore
  • Patent number: 4010517
    Abstract: Sheet support apparatus suitable for mounting sheet material is disclosed. The apparatus is especially useful for displaying information contained on paper or cardboard, or in brochures, etc.The apparatus comprises an elongated, rigid frame including three generally planar and integrally connected wall members spaced to define a cavity therebetween for receiving an edge of sheet material. Anchoring means, such as a leaf spring, are provided which can be inserted and removed from the cavity; the leaf spring cooperates with a shoulder on one wall member to anchor the sheet in the cavity.
    Type: Grant
    Filed: September 12, 1974
    Date of Patent: March 8, 1977
    Inventor: Odd B. Kapstad
  • Patent number: 4007707
    Abstract: A novel development system for controlling the flow rate of developer through a narrow development zone, using a reservoir which has a feed chamber for maintaining a constant pressure head at the entrance to the narrow development zone. Developer flow is initiated upon demand by virtue of actuation of a valve positioned between the feed chamber and the entrance to the development zone; since considerable developer mixing occurs in the developer reservoir, mixing devices for mixing added toner with carrier beads may be simplified.
    Type: Grant
    Filed: January 21, 1975
    Date of Patent: February 15, 1977
    Assignee: Itek Corporation
    Inventors: W. Raymond Buchan, Edward F. Mayer
  • Patent number: 4006271
    Abstract: A process is disclosed for applying an adherent, optically clear, abrasion resistant coating to polycarbonate substrates such as lenses. The process includes: (a) forming a coating solution containing 25-75% of a hydrolyzed C.sub.1 -C.sub.2 alkyltri(lower alkoxy)silane, such as methyltriethoxysilane, in a water-miscible, volatile, organic solvent, and also containing small amounts of an abrasion-resistance enhancer and a stabilizing weak acid; (b) applying a thin, uniform coating of the coating solution to a clean surface of the polycarbonate substrate; and, (c) dehydrating the coated substrate under low humidity conditions at an elevated temperature below the temperature at which the substrate degrades until an adherent, abrasion resistant coating is formed.
    Type: Grant
    Filed: January 28, 1976
    Date of Patent: February 1, 1977
    Assignee: Itek Corporation
    Inventors: Hollis E. French, Juergen M. Kruse
  • Patent number: 4003789
    Abstract: An isolated clonal cell line derived from the mouse fibroblast 3T3 line is disclosed. This 3T3-L1 clonal cell line has the unique characteristic of accumulating large amounts of triglyceride fats in its resting state, which makes it useful for screening drugs to determine their effect on cell fat accumulation.
    Type: Grant
    Filed: January 8, 1975
    Date of Patent: January 18, 1977
    Assignee: Massachusetts Institute of Technology
    Inventor: Howard Green
  • Patent number: 3993825
    Abstract: Apparatus and method for transferring non-fused xerographic toner images from a first support material, such as a photoconductive insulating surface, to a second support material, such as paper, and fusing the toner images to the second support material. Such apparatus includes an intermediate transfer member having a smooth surface of low surface free energy and a hardness of from 3 to 70 durometers. The intermediate transfer member can be, for example, a 0.1-10 mil layer of silicone rubber coated onto a polyimide support. The member can be formed into belt or drum configuration.
    Type: Grant
    Filed: February 20, 1975
    Date of Patent: November 23, 1976
    Assignee: Itek Corporation
    Inventors: William R. Buchan, Robert A. Moore
  • Patent number: 3982935
    Abstract: This disclosure relates to an electrophotographic copying process suitable for use in a multiple copying system. The process is characterized by use of an electrophotographic medium comprising photosensitive organic compounds which are either (1) insulating prior to irradiation and substantially permanently conductive subsequent to irradiation or (2) conductive prior to irradiation and substantially permanently insulating subsequent to irradiation. The process comprises the steps of exposing the electrophotographic medium to a pattern of activating radiation to produce a latent image with a conductivity pattern that is irreversible and permanently altered and externally applying an electrical charge at any suitable time thereby forming an electrostatic pattern which can be developed by any of the known electrophotographic developing techniques.
    Type: Grant
    Filed: August 1, 1974
    Date of Patent: September 28, 1976
    Assignee: Itek Corporation
    Inventors: Richard F. Bartlett, Laura K. Case
  • Patent number: 3973967
    Abstract: A physical developer activator material such as a material which reacts with the oxidized form of the reducing agent component of a physical developer is added to a photographic element comprising physical development nuclei or a photosensitive material capable of generating such nuclei. A preferred physical development activator material is an organic acid or a salt of an organic acid such as ammonium tartrate. This photographic element is utilized in a process comprising forming an image of physical development nuclei and then contacting the medium with a unitary physical developer comprising a solution of metal ions and a reducing agent for these metal ions. The photographic element of this invention is also utilized in a printing process comprising forming an image pattern of physical development nuclei in the photographic element, contacting the element with a unitary physical developer and then using the thus imaged element as a printing plate.
    Type: Grant
    Filed: August 19, 1974
    Date of Patent: August 10, 1976
    Assignee: Itek Corporation
    Inventor: Harry Lerner
  • Patent number: 3970455
    Abstract: A lithographic printing plate is produced by the steps of forming a latent electrostatic image on a photoconductive zinc oxide insulating layer and developing this layer with a toner which forms an imagewise deposit on the recording layer. Applicants' invention relates to contacting the portions of the recording layer which are not covered with the hydrophobic deposit with a hydrophilizing composition (commonly called a conversion wash) comprising the reaction product of (1) phosphoric acid or one of the anions derived from such acid, (2) an organic amine compound, and (3) a hydrophilic metal cation, to form a reaction product with zinc ions from the zinc oxide which reaction product of zinc ions with said composition is substantially insoluble in said composition and is preferentially wetted by water thereby repelling lithographic inks. The plate produced by this process is especially useful for use on a lithographic offset press to produce multiple copies of an original.
    Type: Grant
    Filed: June 4, 1973
    Date of Patent: July 20, 1976
    Assignee: Itek Corporation
    Inventors: Raymond R. Nadeau, John E. Wyman