Patents Represented by Attorney Dean Ersfeld

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  • Imidazonaphthyridines
    Patent number: 6624172
    Abstract: Imidazonaphthydrine compounds that have an aryl containing substituent at the 1-position induce the biosynthesis of cytokines such as interferon and tumor necrosis factor. The compounds exhibit antiviral and antitumor properties. Methods of preparing the compounds and intermediates useful in the preparation of the compounds are also disclosed.
    Type: Grant
    Filed: August 31, 2001
    Date of Patent: September 23, 2003
    Assignee: 3M Innovative Properties Company
    Inventors: Kyle J. Lindstrom, Bryon A. Merrill, Michael J. Rice
  • Process for preparing imidazoquinolinamines
    Patent number: 6624305
    Abstract: A process for preparing 1H-imidazo[4,5-c]quinolin-4-amines is disclosed. The process involves reacting a 6H-imidazo[4,5-c]tetrazolo[1,5-a]quinoline with triphenylphosphine and hydrolyzing the product thereof.
    Type: Grant
    Filed: February 6, 2003
    Date of Patent: September 23, 2003
    Assignee: 3M Innovative Properties Company
    Inventors: John F. Gerster, Kyle J. Lindstrom
  • Process for preparing imidazoquinolinamines
    Patent number: 6613902
    Abstract: A process for preparing 1H-imidazo[4,5-c]quinolin-4-amines is disclosed. The process involves reacting a 6H-imidazo[4,5-c]tetrazolo[1,5-a]quinoline with triphenylphosphine and hydrolyzing the product thereof.
    Type: Grant
    Filed: January 28, 2003
    Date of Patent: September 2, 2003
    Assignee: 3M Innovative Properties Company
    Inventors: John F. Gerster, Kyle J. Lindstrom
  • Process for preparing 1-substituted, 2-substituted 1H-imidazo[4,5-c]quinolin-4-amines
    Patent number: 6608201
    Abstract: Methods of preparing 1-substituted, 2-substituted 1H-imidazo[4,5-c]quinolin-4-amines are disclosed. The compounds function as antiviral agents, they induce the biosynthesis of various cytokines including interferon, and they inhibit tumor formation in animal models.
    Type: Grant
    Filed: September 10, 2002
    Date of Patent: August 19, 2003
    Assignee: 3M Innovative Properties Company
    Inventors: John F. Gerster, Kyle J. Lindstrom
  • Urea substituted imidazoquinolines
    Patent number: 6573273
    Abstract: Imidazoquinoline and tetrahydroimidazoquinoline compounds that contain urea, thiourea, acylurea, or sulfonylurea functionality at the 1-position are useful as immune response modifiers. The compounds and compositions of the invention can induce the biosynthesis of various cytokines and are useful in the treatment of a variety of conditions including viral diseases and neoplastic diseases.
    Type: Grant
    Filed: December 21, 2001
    Date of Patent: June 3, 2003
    Assignee: 3M Innovative Properties Company
    Inventors: Stephen L. Crooks, George W. Griesgraber, Kyle J. Lindstrom, Bryon A. Merrill, Michael J. Rice
  • Amide substituted imidazopyridines
    Patent number: 6545016
    Abstract: Imidazopyridine compounds that contain amide functionality at the 1-position are useful as immune response modifiers. The compounds and compositions of the invention can induce the biosynthesis of various cytokines and are useful in the treatment of a variety of conditions including viral diseases and neoplastic diseases.
    Type: Grant
    Filed: June 7, 2002
    Date of Patent: April 8, 2003
    Assignee: 3M Innovative Properties Company
    Inventors: Joseph F. Dellaria, Chad A. Haraldson, Philip D. Heppner, Kyle J. Lindstrom, Bryon A. Merrill
  • Urea substituted imidazopyridines
    Patent number: 6545017
    Abstract: Imidazopyridine compounds that contain urea or thiourea functionality at the 1-position are useful as immune response modifiers. The compounds and compositions of the invention can induce the biosynthesis of various cytokines and are useful in the treatment of a variety of conditions including viral diseases and neoplastic diseases.
    Type: Grant
    Filed: June 7, 2002
    Date of Patent: April 8, 2003
    Assignee: 3M Innovative Properties Company
    Inventors: Joseph F. Dellaria, Chad A. Haraldson, Philip D. Heppner, Kyle J. Lindstrom, Bryon A. Merrill
  • Urea substituted imidazoquinolines
    Patent number: 6541485
    Abstract: Imidazoquinoline and tetrahydroimidazoquinoline compounds that contain urea, thiourea, acylurea, or sulfonylurea functionality at the 1-position are useful as immune response modifiers. The compounds and compositions of the invention can induce the biosynthesis of various cytokines and are useful in the treatment of a variety of conditions including viral diseases and neoplastic diseases.
    Type: Grant
    Filed: June 7, 2000
    Date of Patent: April 1, 2003
    Assignee: 3M Innovative Properties Company
    Inventors: Stephen L. Crooks, Bryon A. Merrill, Michael J. Rice
  • Process for preparing imidazoquinolinamines
    Patent number: 6534654
    Abstract: A process for preparing 1H-imidazo[4,5-c]quinolin-4-amines is disclosed. The process involves reacting a 6H-imidazo[4,5-c]tetrazolo[1,5-a]quinoline with triphenylphosphine and hydrolyzing the product thereof.
    Type: Grant
    Filed: June 26, 2002
    Date of Patent: March 18, 2003
    Assignee: 3M Innovative Properties Company
    Inventors: John F. Gerster, Kyle J. Lindstrom
  • Sulfonamido substituted imidazopyridines
    Patent number: 6525064
    Abstract: Imidazopyridine compounds that contain sulfonamide functionality at the 1-position are useful as immune response modifiers. The compounds and compositions of the invention can induce the biosynthesis of various cytokines and are useful in the treatment of a variety of conditions including viral diseases and neoplastic diseases.
    Type: Grant
    Filed: June 7, 2002
    Date of Patent: February 25, 2003
    Assignee: 3M Innovative Properties Company
    Inventors: Joseph F. Dellaria, Chad A. Haraldson, Philip D. Heppner, Kyle J. Lindstrom, Bryon A. Merrill
  • Imidazonaphthyridines
    Patent number: 6518280
    Abstract: Imidazonaphthyridine compounds that are unsubstituted at the 2-position induce the biosynthesis of cytokines such as interferon and tumor necrosis factor. The compounds exhibit antiviral and antitumor properties. Methods of preparing the compounds and intermediates useful in the preparation of the compounds are also disclosed.
    Type: Grant
    Filed: August 31, 2001
    Date of Patent: February 11, 2003
    Assignee: 3M Innovative Properties Company
    Inventors: John F. Gerster, Kyle J. Lindstrom
  • Imidazonaphthyridines
    Patent number: 6514985
    Abstract: Imidazonaphthyridine and tetrahydroimidazonaphthyridine compounds induce the biosynthesis of cytokines such as interferon and tumor necrosis factor. The compounds exhibit antiviral and antitumor properties. Methods of preparing the compounds and intermediates useful in the preparation of the compounds are also disclosed.
    Type: Grant
    Filed: November 6, 2000
    Date of Patent: February 4, 2003
    Assignee: 3M Innovative Properties Company
    Inventors: John F. Gerster, Kyle J. Lindstrom, Stephen L. Crooks, Philip D. Heppner, Gregory J. Marszalek, Peter V. Maye, Bryon A. Merrill, John W. Mickelson, Michael J. Rice
  • Process for preparing 1-substituted, 2-substituted 1H-imidazo[4, 5-c]quinoline-4-amines
    Patent number: 6465654
    Abstract: Methods of preparing 1-substituted, 2-substituted 1H-imidazo [4-5c]-quinolin-4-amines are disclosed. The compounds function as antiviral agents, they induce the biosynthesis of various cytokines including interferon, and they inhibit tumor formation in animal models.
    Type: Grant
    Filed: October 9, 2001
    Date of Patent: October 15, 2002
    Assignee: 3M Innovative Properties Company
    Inventors: John F. Gerster, Stephen L. Crooks, Kyle J. Lindstrom
  • Oxazolo, thiazolo and selenazolo [4,5-c]-quinolin-4-amines and analogs thereof
    Patent number: 6440992
    Abstract: Thiazolo-, oxazolo- and selenazolo[4,5-c]quinolin-4-amines and analogs thereof are described including methods of manufacture and the use of novel intermediates. The compounds are immunomodulators and induce cytokine biosynthesis, including interferon and/or tumor biosynthesis, necrosis factor, and inhibit the T-helper-type 2 immune response. The compounds are further useful in the treatment of viral and neoplastic diseases.
    Type: Grant
    Filed: September 24, 2001
    Date of Patent: August 27, 2002
    Assignee: 3M Innovative Properties Company
    Inventors: John F. Gerster, Kyle J. Lindstrom, Gregory J. Marszalek, Bryon A. Merrill, John W. Mickelson, Michael J. Rice