Abstract: Process and composition for reducing intraocular pressure and reducing aqueous humor formation by applying topically to the cornea an effective amount of an aqueous solution of a caronic anhydrase inhibitor comprising a sulfonamide having the following properties:a. sufficiently soluble in water to form at least a 3 mM solution at pH 8.2 or a pKa of not greater than 7.3;b. ether partition coefficient of at least 1.0;c. chloroform partition coefficient of at least 0.01;d. dissociation constant against carbonic anhydrase of not more than 3.times.10.sup.-8 molar;e. first order rate constant for penetration of the sulfonamide through a living rabbit cornea of at least 0.005 hr.sup.-1 ;f. not injurious to the cornea; andg. stable in aqueous solution and in contact with the cornea.

Abstract: A radio receiver for frequency modulated signals in which direct conversion techniques are used to provide zero I.F. quadrature baseband signals I & Q. The I & Q signals are limited (11,12) to form square wave signals and pulse forming networks (13,14) derive pulse sequences the frequencies of which represent the polarity changes in the square wave signals. Each square wave is multiplied (15,16) by the pulse sequence derived from the other square wave to produce a unipolar pulse train. The two unipolar pulse trains are combined (17) to give a digital output signal the frequency of which is equal to the sum of the frequencies of the two pulse trains. Low pass filtering the output signal produces a simulation of the original baseband modulation.

Abstract: The invention provides a method for controlling mammalian body weight using a compound of the formula[E--DHC] (I)or a non-toxic pharmaceutically acceptable salt thereof, wherein [E] is an estrogen and [DHC] is the reduced, biooxidizable, blood-brain barrier penetrating, lipoidal form of a dihydropyridine.revreaction.pyridinium salt redox carrier. Novel compositions for weight control comprising a compound of formula (I) or its salt are also disclosed. A preferred compound for use in the subject method and compositions is an estradiol derivative, namely, 17 .beta.-[(1-methyl-1,4-dihydro-3-pyridinyl)carbonyloxy]estra-1,3,5(10)-trie n-3-ol.

Abstract: A constant voltage circuit has two rails 10 and 12, with one rail 12 at a variable potential V, possibly supplied by a voltaic cell. In one arm between the rails there is voltage reference means Z1, 14, with a circuit output line 16 connected thereto, and the line 16 is required to be maintained at a potential V.sub.o, corresponding to a maximum value for V. In a second arm there is provided a first resistor R1, connected to the rail 12, and in series with a transistor T2. A second, equal, resistor R2 is connected between the output line 16 and the transistor T2. Means Z2, 30, T3, causes a potential, corresponding to the variable, decreasing, potential V, to be applied between the second resistor R2 and the transistor T2. The current to the transistor T2 is constant over a wide range dV for V, by a compensating current portion dI flowing through the second resistor R2, thereby maintaining V.sub. o constant.

Abstract: A cryostat current lead design uses a relatively high (i.e., at room temperature) thermal and electrical conductiveity first tube at its top to minimize joule heating. A relatively low thermal and electrical conductivity second tube is disposed below the first tube and thermally insulates the current lead to lesson the zero current loss. A superconductivity lead accomodating lower member is attached at the bottom of the second tube with strands of wire extending from the interior of the first tube to the interior of the lower member which preferably is a tube. Superconducting leads may be attached by lead-tin alloy (soft) solder at the outside of the lower member. The method of the present invention is the use of the current lead to provide electrical power to a device within the liquid helium bath of the cryostat. Preferably, the room temperature resistance of the lead is between 0.7 volts and 1.0 volts divided by the maximum current to be carried.

Abstract: System for monitoring a plurality of containers using ultrasonic seals integral with the containers and electronic circuits connected to these seals, wherein:(A) each seal comprises an ultrasonic transmitting transducer and an ultrasonic receiving transducer making it possible to check both the identity of the marking and the integrity of the seal, the marking being located outside the seal body,(B) the electronic circuits connected to these seals comprise:(a) at least one cyclic, sequential module for the auscultation or listening to the seals having the same number of outputs and inputs as there are seals, the outputs being connected to the transmitting transducers and the inputs to the receiving transducers,(b) at least one electronic processing module connected to the listening module and controlling a sampling of the signal received.

Abstract: A device for the controlled release of an active material into an aqueous medium comprises a porous sintered body of a water soluble glass (11). The pores of the body are filled with a composition (12) consisting wholly or partially of an active material. The device may be provided with a low solubility coating (13). On immersion in an aqueous medium the glass (11) dissolves to become a sponge-like structure having a plurality of convoluted capillaries and from which the active material is released.

Abstract: An electrical circuit assembly uses a plurality of stacks upon a generally planar support. Each constituent stack has a plurality of modules having planar substrates extending at right angles to a longitudinal axis of symmetry of the stack. The axis of symmetry is perpendicular to the generally planar support and various electrical interconnections extend between adjacent substrates parallel to this axis. Electrical circuit elements are mounted upon the substrates and the substrates are spaced to facilitate flow of cooling fluid, such as air, between the substrates. Heat conducting fins may be mounted on the substrates. To facilitate flow of cooling fluid, stacks of substrates are staggered or offset from substrates of an adjacent stack. A plurality of the electrical circuit assemblies may be combined together.

Abstract: A circuit for converting a TV receiver to operate in accordance with the system associated with received signals, there being either F or F' scan lines in a field, with F<F', includes a counter driven by pulses each representative of one end of a raster scan line, and having M stages, with F and F'<M<2F and 2F'. There is also means to preload the counter selectively with a count of R or R', where (M-2R)=F and (M-2R')=F'. Wide window means detects when a field sync pulse is within a window including the (M-R)th and (M-R') stages, and, in response, the counter, initially, is preloaded with R'. Decision logic means then detects whether a field sync pulse occurs after the Kth stage, with K=M-[R+R']/2, when R' is continued to be preload; or occurs before the Kth stage, when R subsequently is preloaded; and the required TV receiver conversion is completed.

Abstract: Insulation flaws in electrical components are detected by measurement of electrical leakage before and after immersion in a mobile ionizing solvent, e.g. a lower alkyl alcohol. A significant increase in leakage is indicative of a flaw, e.g. a crack in the insulation.

Abstract: Sanitary pads for men are disposable in a storage mode in which they are flat and non-overlapping for easy carrying in pockets. The sanitary pads may be folded in order to form generally semi-cylindrical portions which envelop the wearer's penis and prevent embarrassment to incontinent men. In the storage or carrying mode, the pad may alternately be T-shaped or constructed in a generally rectangular shape. Adhesive means, such as double sided tape, or fabric loop and hook fasteners may be used to secure the pads in proper position. The pads are a layered structure including an inner relatively thick layer of absorbent material, a water barrier layer made of plastic, and an outer relatively thin absorbent layer.

Abstract: A diaper holder comprising of vinyl material material for cloth diapers, having horizontal bands of double vinyl secured at the ends to form an open loop at the top and bottom below the waistbands to hold standard cloth diapers securely in place. The lateral sides of the holder are incurved and elasticized to form leg embracing openings. The waistbands are double vinyl and size adjustable with the use of a releasable fastener of hook and pile. Also as a liner when covered with fabric.

Abstract: An optical fibre is provided with a moisture barrier layer by exposing a plastics coating on the fibre to a pulsed plasma in order to modify the surface, for instance by implantation of silicon and/or by the deposition on the plastics layer an inorganic layer such as a non-stoichiometric composition of silicon and carbon or silicon and nitrogen.

Abstract: The present invention relates to a process and an apparatus for storing contaminated waste material by compacting. The waste material is placed in a drum, it is compressed by forcing a precover into the drum and whose edges are made deformable in order to prevent the rising of the precover, by its edges locking on the walls of the drum, particularly by engaging in grooves made in these walls. The cycle is then repeated until the drum is completely full. Application to the storage of radioactive waste.

Abstract: Polysilicon elements of integrated circuits, for example gates (24) or interconnects, are provided with metallic silicide layers (26) in order to take advantage of the lower resistivity thereof. The polysilicon elements are defined on an oxide layer (23) disposed on a silicon substrate (20) before polysilicon metallization. After polysilicon metallization the metal and polysilicon are caused to interdiffuse to form silicide layers (26) covering the polysilicon elements (24).

Abstract: Chemical compounds useful in the treatment of metabolic disorders comprising the reaction product of thiamine and a dichloroacetic acid.

Abstract: All the layers of the anode foil of an electrolytic capacitor roll (5) are cold welded to a piece of tabbing (8) using radiussed weld tooling (10, 12, 13) which bends the foil layers in the course of the welding operation so as to enable a good weld to be effected. The cathode foil layers are welded to their piece of tabbing in the same way. Optionally the roll may be partially flattened at the time the welds are made.

Abstract: The subject compounds, which are adapted for the site-specific/sustained delivery of centrally acting drug species to the brain, are:(a) compounds of the formula[D-DHC] (I)wherein [D] is a centrally acting drug species, and [DHC] is the reduced, biooxidizable, blood-brain barrier penetrating lipoidal form of a dihydropyridine .revreaction. pyridinium salt redox carrier, with the proviso that when [DHC] is ##STR1## wherein R is lower alkyl or benzyl and [D] is a drug species containing a single NH.sub.2 or OH functional group, the single OH group when present being a primary or secondary OH group, said drug species being linked directly through said NH.sub.

Abstract: A gas rich in methane is prepared by the methanantion of a synthesis gas containing carbon oxides, hydrogen and optionally other gases in the presence of one or more gaseous sulphur compounds, normally in an amount of at least 10 ppm preferably at least 200 ppm by volume, calculated as H.sub.2 S, with the aid of a catalyst comprising vanadium and/or molybdenum, which during the process is present as one or more sulphides, on a support comprising titanium dioxide.A high activity and a high selectivity for methane are obtained. A further advantage is that, by far, the main constituent of the higher hydrocarbons formed is ethane, which, by conversion into ethylene, is an important raw material in petrochemical synthesis.The selectivity for methane formation may be further improved by promoting the catalyst with compounds, especially sulphides of metals of groups IA, IIA and/or IIIB, particularly cerium.

Abstract: In a digital PCM-TDM telephone exchange, supervisory tones needed are centrally generated by a digital synthesizer. This includes a PROM (1) in which PCM codes for the tones needed are stored in successive memory locations. The tones used are the DR tone, which is a mixture of 350 Hz and 440 Hz, and the BN tone, which is 400 Hz. These are read out under clock pulse control (5-6-7) such that the DR tone bytes are read out at time slot 0 and the BN tone bytes are read out at time slot 1. They are then sent over a common intelligence bus (4) to all line and trunk interfaces.At each such interface the tone bytes are converted to analogue form so as to be continuously available. The tone (or tones) to be used is (or are) selected in response to instructions from the central control each of which specifies a program in the interface's processor. Such a program controls both the selection of the tone (or tones) needed, and the cadence (continuous, or interrupted in a defined manner).