Patents Represented by Attorney Dorene M. Price
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Patent number: 7855021Abstract: The invention relates to platinum-coated particles useful as fuel cell electrocatalysts. The particles are composed of a noble metal or metal alloy core at least partially encapsulated by an atomically thin surface layer of platinum atoms. The invention particularly relates to such particles having a palladium, palladium alloy, gold alloy, or rhenium alloy core encapsulated by an atomic monolayer of platinum. In other embodiments, the invention relates to fuel cells containing these electrocatalysts and methods for generating electrical energy therefrom.Type: GrantFiled: June 20, 2005Date of Patent: December 21, 2010Assignee: Brookhaven Science Associates, LLCInventors: Radoslav Adzic, Yibo Mo, Miomir Vukmirovic, Junliang Zhang
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Patent number: 7837976Abstract: In one aspect, the invention relates to activated aluminum hydride hydrogen storage compositions containing aluminum hydride in the presence of, or absence of, hydrogen desorption stimulants. The invention particularly relates to such compositions having one or more hydrogen desorption stimulants selected from metal hydrides and metal aluminum hydrides. In another aspect, the invention relates to methods for generating hydrogen from such hydrogen storage compositions.Type: GrantFiled: July 29, 2005Date of Patent: November 23, 2010Assignee: Brookhaven Science Associates, LLCInventors: Gary Sandrock, James Reilly, Jason Graetz, James E. Wegrzyn
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Patent number: 7759109Abstract: A bacterial growth medium for promoting auto-induction of transcription of cloned DNA in cultures of bacterial cells grown batchwise is disclosed. The transcription is under the control of a lac repressor. Also disclosed is a bacterial growth medium for improving the production of a selenomethionine-containing protein or polypeptide in a bacterial cell, the protein or polypeptide being produced by recombinant DNA techniques from a lac or T7lac promoter, the bacterial cell encoding a vitamin B12-dependent homocysteine methylase. Finally, disclosed is a bacterial growth medium for suppressing auto-induction of expression in cultures of bacterial cells grown batchwise, said transcription being under the control of lac repressor.Type: GrantFiled: April 4, 2008Date of Patent: July 20, 2010Assignee: Brookhaven Science Associates, LLCInventor: F. William Studier
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Patent number: 7714317Abstract: In some embodiments of the invention, encapsulated semiconducting nanomaterials are described. In certain embodiments the nanostructures described are semiconducting nanomaterials encapsulated with ordered carbon shells. In some aspects a method for producing encapsulated semiconducting nanomaterials is disclosed. In some embodiments applications of encapsulated semiconducting nanomaterials are described.Type: GrantFiled: September 12, 2007Date of Patent: May 11, 2010Assignee: Brookhaven Science Associates, LLCInventors: Eli Anguelova Sutter, Peter Werner Sutter
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Patent number: 7704722Abstract: Methods for promoting and suppressing auto-induction of transcription of cloned DNA in cultures of T7 expression strains are disclosed.Type: GrantFiled: April 27, 2007Date of Patent: April 27, 2010Assignee: Brookhaven Science Associates, LLCInventor: F. William Studier
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Patent number: 7704919Abstract: The invention relates to gold-coated particles useful as fuel cell electrocatalysts. The particles are composed of an electrocatalytically active core at least partially encapsulated by an outer shell of gold or gold alloy. The invention more particularly relates to such particles having a noble metal-containing core, and more particularly, a platinum or platinum alloy core. In other embodiments, the invention relates to fuel cells containing these electrocatalysts and methods for generating electrical energy therefrom.Type: GrantFiled: August 1, 2005Date of Patent: April 27, 2010Assignee: Brookhaven Science Associates, LLCInventors: Radoslav Adzic, Junliang Zhang
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Patent number: 7704918Abstract: The invention relates to platinum-metal oxide composite particles and their use as electrocatalysts in oxygen-reducing cathodes and fuel cells. The invention particularly relates to methods for preventing the oxidation of the platinum electrocatalyst in the cathodes of fuel cells by use of these platinum-metal oxide composite particles. The invention additionally relates to methods for producing electrical energy by supplying such a fuel cell with an oxidant, such as oxygen, and a fuel source, such as hydrogen. The invention also relates to methods of making the metal-metal oxide composites.Type: GrantFiled: June 8, 2007Date of Patent: April 27, 2010Assignee: Brookhaven Science Associates, LLCInventors: Radoslav Adzic, Miomir Vukmirovic, Kotaro Sasaki
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Patent number: 7691627Abstract: The invention provides recombinant human CAR (coxsackievirus and adenovirus receptor) polypeptides which bind adenovirus. Specifically, polypeptides corresponding to adenovirus binding domain D1 and the entire extracellular domain of human CAR protein comprising D1 and D2 are provided. In another aspect, the invention provides nucleic acid sequences encoding these domains and expression vectors for producing the domains and bacterial cells containing such vectors. The invention also includes an isolated fusion protein comprised of the D1 polypeptide fused to a polypeptide which facilitates folding of D1 when expressed in bacteria. The functional D1 domain finds application in a therapeutic method for treating a patient infected with a CAR D1-binding virus, and also in a method for identifying an antiviral compound which interferes with viral attachment. The invention also provides a method for specifically targeting a cell for infection by a virus which binds to D1.Type: GrantFiled: October 17, 2006Date of Patent: April 6, 2010Assignee: Brookhaven Science Associates, LLCInventor: Paul I. Freimuth
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Patent number: 7691780Abstract: The present invention relates to particle and nanoparticle composites useful as oxygen-reduction electrocatalysts. The particle composites are composed of a palladium or palladium-alloy particle or nanoparticle substrate coated with an atomic submonolayer, monolayer, bilayer, or trilayer of zerovalent platinum atoms. The invention also relates to a catalyst and a fuel cell containing the particle or nanoparticle composites of the invention. The invention additionally includes methods for oxygen reduction and production of electrical energy by using the particle and nanoparticle composites of the invention.Type: GrantFiled: December 22, 2004Date of Patent: April 6, 2010Assignee: Brookhaven Science Associates, LLCInventors: Radoslav Adzic, Junliang Zhang, Yibo Mo, Miomir Branko Vukmirovic
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Patent number: 7643610Abstract: A radiation delivery system generally includes either a synchrotron source or a support frame and a plurality of microbeam delivery devices supported on the support frame, both to deliver a beam in a hemispherical arrangement. Each of the microbeam delivery devices or synchrotron irradiation ports is adapted to deliver at least one microbeam of radiation along a microbeam delivery axis, wherein the microbeam delivery axes of the plurality of microbeam delivery devices cross within a common target volume.Type: GrantFiled: October 4, 2007Date of Patent: January 5, 2010Assignee: Brookhaven Science Associates, LLCInventor: F. Avraham Dilmanian
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Patent number: 7632601Abstract: The present invention relates to palladium-cobalt particles useful as oxygen-reducing electrocatalysts. The invention also relates to oxygen-reducing cathodes and fuel cells containing these palladium-cobalt particles. The invention additionally relates to methods for the production of electrical energy by using the palladium-cobalt particles of the invention.Type: GrantFiled: February 10, 2005Date of Patent: December 15, 2009Assignee: Brookhaven Science Associates, LLCInventors: Radoslav Adzic, Tao Huang
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Patent number: 7622426Abstract: The present invention is a method for producing a crystalline end-product. The method comprising exposing a fluoride-containing precursor to a hydrogen fluoride absorber under conditions suitable for the conversion of the precursor into the crystalline end-product.Type: GrantFiled: October 6, 2005Date of Patent: November 24, 2009Assignee: Brookhaven Science Associates, LLCInventors: Vyacheslav Solovyov, Harold Wiesmann
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Patent number: 7601042Abstract: An electron gun for generating an electron beam is provided, which includes a secondary emitter. The secondary emitter includes a non-contaminating negative-electron-affinity (NEA) material and emitting surface. The gun includes an accelerating region which accelerates the secondaries from the emitting surface. The secondaries are emitted in response to a primary beam generated external to the accelerating region. The accelerating region may include a superconducting radio frequency (RF) cavity, and the gun may be operated in a continuous wave (CW) mode. The secondary emitter includes hydrogenated diamond. A uniform electrically conductive layer is superposed on the emitter to replenish the extracted current, preventing charging of the emitter. An encapsulated secondary emission enhanced cathode device, useful in a superconducting RF cavity, includes a housing for maintaining vacuum, a cathode, e.g.Type: GrantFiled: April 12, 2007Date of Patent: October 13, 2009Assignee: Brookhaven Science Associates, LLCInventors: Triveni Srinivasan-Rao, Ilan Ben-Zvi
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Patent number: 7589248Abstract: Mercury is removed from contaminated waste by firstly applying a sulfur reagent to the waste. Mercury in the waste is then permitted to migrate to the reagent and is stabilized in a mercury sulfide compound. The stable compound may then be removed from the waste which itself remains in situ following mercury removal therefrom.Type: GrantFiled: June 11, 2008Date of Patent: September 15, 2009Assignee: Brookhaven Science Associates, LLCInventors: Mark Fuhrmann, John Heiser, Paul Kalb
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Patent number: 7582886Abstract: A particle therapy gantry for delivering a particle beam to a patient includes a beam tube having a curvature defining a particle beam path and a plurality of fixed field magnets sequentially arranged along the beam tube for guiding the particle beam along the particle path. In a method for delivering a particle beam to a patient through a gantry, a particle beam is guided by a plurality of fixed field magnets sequentially arranged along a beam tube of the gantry and the beam is alternately focused and defocused with alternately arranged combined function focusing and defocusing fixed field magnets.Type: GrantFiled: May 12, 2006Date of Patent: September 1, 2009Assignee: Brookhaven Science Associates, LLCInventor: Dejan Trbojevic
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Patent number: 7560264Abstract: Disclosed is a method for promoting auto-induction of transcription of cloned DNA in cultures of bacterial cells grown batchwise, the transcription being under the control of a promoter whose activity can be induced by an exogenous inducer whose ability to induce said promoter is dependent on the metabolic state of said bacterial cells. Initially, a culture media is provided which includes: i) an inducer that causes induction of transcription from said promoter in said bacterial cells; and ii) a metabolite that prevents induction by said inducer, the concentration of said metabolite being adjusted so as to substantially preclude induction by said inducer in the early stages of growth of the bacterial culture, but such that said metabolite is depleted to a level that allows induction by said inducer at a later stage of growth. The culture medium is inoculated with a bacterial inoculum, the inoculum comprising bacterial cells containing cloned DNA, the transcription of which is induced by said inducer.Type: GrantFiled: September 30, 2003Date of Patent: July 14, 2009Assignee: Brookhaven Science Associates, LLCInventor: F. William Studier
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Patent number: 7521037Abstract: The present invention provides methods and materials for the formation of hydrogen storage alanes, AlHx, where x is greater than 0 and less than or equal to 6 at reduced H2 pressures and temperatures. The methods rely upon reduction of the change in free energy of the reaction between aluminum and molecular H2. The change in free energy is reduced by lowering the entropy change during the reaction by providing aluminum in a state of high entropy, by increasing the magnitude of the change in enthalpy of the reaction or combinations thereof.Type: GrantFiled: July 31, 2007Date of Patent: April 21, 2009Assignee: Brookhaven Science Associates, LLCInventors: Jason Allan Graetz, James J. Reilly
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Patent number: 6958163Abstract: The invention relates to structured water and its antioxidant activity. In addition, the present invention relates to antioxidants incorporated within the cluster structure of either electropositive (S water) or electronegative (I water). The structured water, having the antioxidant within its cluster structure, has a stabilizing effect on the antioxidant. In addition, the antioxidant activity inherent to structured water is enhanced by the presence of the antioxidant within its cluster structure. The present invention also includes methods of removing or reducing free radicals on the skin and thereby preventing the signs of skin aging and the risks of cancer associated with the presence of free radicals in the skin.Type: GrantFiled: June 27, 2002Date of Patent: October 25, 2005Assignee: Color Access, Inc.Inventors: Vasile Ionita-Manzatu, Mirela Ionita-Manzatu, Gheorghe Cioca, Andrew J. Bevacqua
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Patent number: 6905696Abstract: The present invention relates to a cosmetic or pharmaceutical composition for topical application to the keratinous surface which comprises a alignment agent for promoting the orderly arrangement of a feature enhancing component for enhancing the lengthening of the eyelashes and/or the covering of wrinkles on the skin surface. The feature enhancing component can be a fibrous component and can include a variety of types of fibers including wicking fibers, evaporating fibers, or a combination of both. The feature enhancing component can also be inert fillers such as platelet materials.Type: GrantFiled: January 6, 2003Date of Patent: June 14, 2005Assignee: Color Access, Inc.Inventors: Paul H. Marotta, John R. Castro, Carl C. Orr, Helen Sung, David Peters
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Patent number: 6905523Abstract: The invention relates to methods of coloring the hair with cluster-modified water and the ability to achieve enhanced color and conditioning for the hair that is color-treated. The cluster-modified water can be ionized water such as alkalinic or acidic water, or structured water such as I or S water. In addition, the cluster-modified water can be applied to the hair as a pre-saturating treatment and/or a post-saturating treatment relative to the hair color treatment process. Additional benefits of the present invention are the ability to minimize the use of harsh chemicals and dyes while still achieving an enriched color, and increased softness and smoothness to the color-treated hair. The present invention can also be used with mordanting salts. The present invention also includes a hair coloring kit including the cluster-modified water for post-saturating and/or pre-saturating the hair.Type: GrantFiled: March 13, 2003Date of Patent: June 14, 2005Assignees: Aveda Corporation, Color Access, Inc.Inventors: Alex Vainshelboim, Peter Matravers, Asira Ostrovskaya, Kimberly Switlick, Julie Dachtera, Vasile Ionita-Manzatu, George Cioca, Harvey Gedeon, Geoffrey Hawkins, Michael Hayes