Abstract: The present invention relates to a process for the preparation of 2-{4-[4-(4-chloro-1-pyrazolyl)buty1]-1-piperazinyl}pyrimidine (Lesopitron) of formula I: ##STR1## characterized in that the reaction between 2-(1-piperazinyl)pyrimidine, 4-chloropyrazole and the carbon chain of formula (III) ##STR2## in which X and Y, which may be identical or different, represent a suitable leaving group, is carried out in a single step in a suitable solvent.
Type:
Grant
Filed:
May 9, 1994
Date of Patent:
July 16, 1996
Assignee:
Laboratorios Del Dr. Esteve, S.A.
Inventors:
Ramon Merce-Vidal, Jordi Frigola-Constansa
Abstract: A panel member consisting of inner and outer interconnected panels, and reinforcement members placed therebetween to increase the strength of said panel in localized areas. The reinforcements consist of a structure made up of a base material of plastic or aluminum and an insert material of a hard metal. Loads are transferred to the panel through the metal insert material and dissipated to the panel members through the base structure. In the illustrated arrangements, the reinforcement members are used, for example, in the latch and hinge areas of car hoods.
Abstract: Disclosed herein is a method for controlling sapstain in wood and wood products comprising a) steam pasteurizing the wood or wood product followed by b) treating the wood or wood product with a biological control agent comprising one or more fungi selected from the class Hyphomycetes. Also disclosed are wood or wood products so treated.
Abstract: A method and apparatus for securely writing confidential data from an issuerer to a customer smart card at a remote location includes, establishing a communication link between a retailer data terminal device at the remote location and the issuer's secure computer. A communication link is established between a secure terminal device, which includes a smart card reader/writer, and the data terminal device. The retailer is authenticated to the issuer and the issuer to the retailer by means of a retailer smart card presented to the secure terminal device. A session key is established for enciphering data traffic between the secure terminal device and the issuer's computer using the retailer smart card. The customer smart card is presented to the secure terminal device. Confidential customer data is enciphered using the session key and it is written from the issuer's computer to the customer smart card.
Abstract: A center star assembly for use with a capping machine where the center star assembly can be quickly removed from the capping machine and replaced with another center star assembly for handling different size bottles or containers without having to remove and reinstall any fasteners or other mounting components.
Type:
Grant
Filed:
November 3, 1994
Date of Patent:
July 9, 1996
Assignee:
Aluminum Company of America
Inventors:
Edgar E. Adams, Darwin L. Ellis, Gerald E. Stelle
Abstract: A readily assemblable and disassemblable cart has snap-locking vertical and lateral members. The vertical members and top and bottom rails include notched end portions which define extended portions. The lateral rails have bores formed in each of the ends thereof for receiving two of the extended portions. The extended portions also include latching members which, when the cart is assembled, extend into openings in the lateral rails which are transverse to, and contiguous with the bores.
Abstract: The present invention relates to the use of 1-{4-[4-aryl(or heteroaryl)-1-piperazinyl]butyl}-1H-azole derivatives and of their physiologically acceptable salts for the manufacture of medicaments intended for the treatment of disorders associated with gastric secretion.
Type:
Grant
Filed:
November 23, 1994
Date of Patent:
July 2, 1996
Assignee:
Laboratories Del Dr. Esteve, S.A.
Inventors:
Jordi Frigola-Constansa, Ramon Merce-Vidal
Abstract: A cartridge for a closure, and a closure containing such a cartridge, are provided for accommodating the dispensing of a liquid product from a container. The cartridge includes a body, a valve seated in the body, and a retainer engaged with the body to hold the retainer and body in a clamping relationship retaining the valve in position on the body. A standardized valve and overall cartridge design may be employed with a variety of different closure housings for different containers.
Type:
Grant
Filed:
June 10, 1994
Date of Patent:
July 2, 1996
Assignee:
Aptargroup, Inc.
Inventors:
Richard A. Gross, Eldon W. Schaffer, II
Abstract: Disclosed is a method/apparatus to determine any one of a plurality of parameters: shape, area, chemical composition, diameter, color, number, thickness, width, length, absorptivity, reflectivity, transmittivity, dielectric constant, raman scattering profile, fluorescence, surface tension, roughness, profile, density, position and orientation. Also use of a plurality of energy beams as source energy: charged and neutral particle beams, gamma-, X-, micro-, optical and acoustic waves. The described apparatus determines the mean and standard deviation of a plurality of diameters of wool fibers, and includes a He-Ne laser (101), and a pinhole (102) which produce an expanding laser beam which passes through cell (105). Beam splitter (103) is operatively disposed to pinhole (102) and laser (101) to direct a portion of the laser beam to reference detector (109) which is electrically connected to processor (110) via line (111).
Type:
Grant
Filed:
March 2, 1994
Date of Patent:
June 25, 1996
Assignee:
Commonwealth Scientific and Industrial Research
Inventors:
Chistopher J. Cantrall, Timothy P. Dabbs, Monty Glass, William Humphries, Leslie J. Wills
Abstract: An emergency breathing device for use of evacuation in connection with fires, chemical accidents or the like, and which comprises a heat-resisting and gas-tight protective hood (1) which is adapted to surround the head (2) of a user, and wherein there are arranged an oxygen supply unit having a reservoir (12) for the supply of oxygen to the breathing air in the hood, and a CO.sub.2 absorber (14) for purifying the breathing air. The hood (1) has double walls (3, 4) for providing a closed breathing bag (5) which is separated from the surrounding atmosphere and which is provided with a suitable positioned mouthpiece (7) for use by the user. Further, the oxygen supply unit comprises a dosing means (40) which is arranged to inject oxygen in accordance with the breathing frequency of the user.
Abstract: A support beam for a storage rack has a tubular profile, which defines a ledge opening upwardly and inwardly, and which defines a generally flat, indicia-receiving surface facing outwardly and either downwardly or upwardly at an angle from about 20.degree. to about 70.degree. relative to a vertical plane. Alternatively, the tubular profile may define two such surfaces defining an obtuse angle relative to each other, namely an upper surface at an angle from about 20.degree. to about 45.degree. relative thereto and a lower surface at an angle from about 45.degree. to about 70.degree. relative thereto, or a generally arcuate, indicia-receiving surface having a suitable measurement. The indicia-receiving surface enables a person who is standing, or who is sitting on a lift truck, to have a generally perpendicular line of sight to such surface. The support beam may also be used in combination with a properly positioned fire extinguishing device to extinguish a fire in a supported load.
Abstract: An apparatus for filling containers including a pump housing having a pump chamber, a product inlet in communication with a supply of product under pressure, a product outlet and a piston positioned therein. The piston is movable by the supply of product under pressure between advancing and retracting positions where product is discharged from the chamber and through the outlet during the advancing stroke and the chamber is filled with product during the retracting stroke. A first valve is included to regulate the flow of product through the outlet and a second valve is included to regulate the flow of product between opposite sides of the piston. By controlling the opening and closing of the first and second valves, the pressure of the product enables movement of the piston to eject product and fill the chamber as desired.
Abstract: This invention is directed to a magnetic resonance imaging composition for imaging of an organ or organ system comprising an organic silicon compound. Preferably, the organ system is the gastrointestinal tract. The present invention is further directed to a method of diagnosis comprising administering to a mammal a contrast effective amount of an organic silicon compound suspended or dispersed in a physiologically tolerable carrier and generating a magnetic resonance image of said mammal. In a preferred embodiment, the organic silicon compound is a silane. In another preferred embodiment, the organic silicon compound is a siloxane. In yet another preferred embodiment, the organic silicon compound is a polysiloxane.