Patents Represented by Attorney Edmunde D. Riedl
  • Patent number: 4160742
    Abstract: Use of copolymers of acrylamide and methylacrylamidopropyltrimethylammmonium chloride to deemulsify oil-in-water emulsions especially in waste streams prior to their discharge from petroleum refineries, industrial plants and the like.
    Type: Grant
    Filed: June 15, 1978
    Date of Patent: July 10, 1979
    Assignee: Calgon Corporation
    Inventor: Manjeri S. Raman
  • Patent number: 4159254
    Abstract: 1,3,5-s-Hexahydrotrisubstituted triazines exemplified by 1,3,5-tris(tetrahydrofurfuryl)-1,3,5-hexahydro-s-triazines are useful as antimicrobial agents particularly when employed as a component of metal-working compositions subject to fungal and bacterial attack.
    Type: Grant
    Filed: May 22, 1978
    Date of Patent: June 26, 1979
    Assignee: Merck & Co., Inc.
    Inventors: Nathaniel Grier, Bruce E. Witzel
  • Patent number: 4159253
    Abstract: 1,3,5-s-Hexahydrotrisubstituted triazines exemplified by 1,3,5-tris(furfuryl)-1,3,5-hexahydro-s-triazines are useful as antimicrobial agents particularly when employed as a component of metal-working compositions subject to fungal and bacterial attack.
    Type: Grant
    Filed: May 22, 1978
    Date of Patent: June 26, 1979
    Assignee: Merck & Co., Inc.
    Inventors: Nathaniel Grier, Bruce E. Witzei
  • Patent number: 4158643
    Abstract: A carbon supported catalyst used for carbon monoxide oxidation is chemically modified by treating the activated carbon support with an oxidizing agent and/or a hydrophobic compound prior to impregnation with the catalyst mixture. The thus treated catalytic carbon is capable of oxidizing carbon monoxide in an air stream containing sulfur dioxide over an extended period of time.
    Type: Grant
    Filed: September 9, 1977
    Date of Patent: June 19, 1979
    Assignee: Calgon Corporation
    Inventor: Rabindra K. Sinha
  • Patent number: 4156010
    Abstract: The isomer (R)-(-)-3-{[2-(p-hydroxyphenyl)-1-methylethyl]-aminomethyl}-3,4-dihydro-2H -1,5-benzodioxepin-3-ol and its non-toxic acid addition salts is unexpectedly more potent in the reduction of elevated interocular pressure in mammals than its enantiomorph or the racemate thereof.
    Type: Grant
    Filed: December 27, 1977
    Date of Patent: May 22, 1979
    Assignee: Merck & Co., Inc.
    Inventor: Ralph F. Hirschmann
  • Patent number: 4154750
    Abstract: Phospholipid-containing vegetable oils, especially soya oil, are treated by an improved refining method comprising the steps of degumming the crude vegatable oil, passing the degummed oil through a bed of granular activated carbon, and finally subjecting the treated vegetable oil to steam assisted vacuum distillation deodorization. The process yields a final product acceptable in taste, odor and color and storage stable for normal shelf life periods.
    Type: Grant
    Filed: May 22, 1978
    Date of Patent: May 15, 1979
    Assignee: Calgon Corporation
    Inventors: Hal E. Moore, James B. Yeates
  • Patent number: 4154845
    Abstract: Novel 6-methoxy and 6-thioalkyl-6-acylamido-penicillanic acids and their non-toxic pharmaceutically-acceptable salts, esters and amides which are useful as antibiotics. The products are prepared by treating an ester of 6-substituted-6-aminopenicillanic acid with an acylating agent followed by removal of the ester group. Also disclosed are novel intermediates.
    Type: Grant
    Filed: September 8, 1977
    Date of Patent: May 15, 1979
    Assignee: Merck & Co., Inc.
    Inventors: Burton G. Christensen, Lovji D. Cama
  • Patent number: 4150045
    Abstract: A novel impregnated activated carbon, containing from about 1.0 percent to about 15.0 percent by weight of MgO, has been found to be useful in a method of decolorizing a crude vegetable oil or a degummed vegetable oil, and removing organic acids therefrom, as well as in a process for making a refined edible vegetable oil wherein a crude vegetable oil is degummed, passed through the impregnated activated carbon, and subjected to steam distillation at reduced pressure. A novel method of preparing the MgO impregnated activated carbon has also been discovered.
    Type: Grant
    Filed: April 24, 1978
    Date of Patent: April 17, 1979
    Assignee: Calgon Corporation
    Inventor: Rabindra K. Sinha
  • Patent number: 4149983
    Abstract: Compositions of 1,3,5-tris-(furfuryl)hexahydro-s-triazine are useful as antimicrobial agents particularly when added to metal-working compositions subject to fungal and bacterial attack.
    Type: Grant
    Filed: April 3, 1978
    Date of Patent: April 17, 1979
    Assignee: Merck & Co., Inc.
    Inventors: Nathaniel Grier, Bruce E. Witzel
  • Patent number: 4145346
    Abstract: A process for preparing 3.beta.-hydroxy-27-norcholest-5-ene-25-one, a useful intermediate in the synthesis of 25-acetoxy vitamin D.sub.3, novel intermediates, and preparation thereof are disclosed.
    Type: Grant
    Filed: October 3, 1977
    Date of Patent: March 20, 1979
    Assignee: Merck & Co., Inc.
    Inventors: Howard Jones, Robert A. Frankshun
  • Patent number: 4145426
    Abstract: Compounds of the structure: ##STR1## where A is either ##STR2## where R.sub.1 to R.sub.4 are various substituents are active as antibacterials and antifungals.
    Type: Grant
    Filed: July 18, 1977
    Date of Patent: March 20, 1979
    Assignee: Merck & Co., Inc.
    Inventors: Nathaniel Grier, Richard A. Dybas, Bruce E. Witzel
  • Patent number: 4139559
    Abstract: A process for preparing 1-[1,5-di-(3,3-dimethylnorborn-2-yl)-3-pentyl]-1,5,9-triazanonane from 1,5-di-(3,3-dimethylnorborn-2-yl)-3-pentanone by reaction with ammonia to form, after reduction, 3-amino-[1,5-di-(3,3-dimethylnorborn-2-yl)pentane]. This latter compound is reacted with acrylonitrile, reduced, and the diamine product again reacted with acrylonitrile and again reduced. Alternative routes wherein the ketone is reduced to the novel alcohol and optionally the novel halide and either then reacted with 3,3'-iminobispropylamine to form the desired polyamine are also shown.
    Type: Grant
    Filed: January 16, 1978
    Date of Patent: February 13, 1979
    Assignee: Merck & Co., Inc.
    Inventors: Nathaniel Grier, Richard A. Dybas, Robert A. Strelitz
  • Patent number: 4134214
    Abstract: The purified Group A polysaccharide antigen isolated from N. meningitidis for vaccination against this type of bacterial meningitidis is prepared from an isotonic ratio of aqueous sodium chloride solution freeze-dried at temperatures of from -20.degree. C. to -30.degree. C. This low temperature lyophilization dries the sodium chloride polysaccharide menstrum without loss of molecular weight, i.e., potency.
    Type: Grant
    Filed: August 5, 1977
    Date of Patent: January 16, 1979
    Assignee: Merck & Co., Inc.
    Inventors: Glen D. Graham, William A. Sklarz
  • Patent number: 4127584
    Abstract: 2-R.sup.1 -Substituted-3-amino-R.sup.2 -substituted-1,2,5-thiadiazolium salts have broad spectrum antibacterial and antifungal activity. They are useful for cleansing inanimate surfaces as well as agents for agriculture.
    Type: Grant
    Filed: November 11, 1977
    Date of Patent: November 28, 1978
    Assignee: Merck & Co., Inc.
    Inventors: Joshua Rokach, Edward J. Cragoe, Jr, Clarence S. Rooney, Grant W. Reader
  • Patent number: 4125482
    Abstract: A novel impregnated activated carbon, containing from about 1.0 percent to about 15.0 percent by weight of MgO, has been found to be useful in a method of decolorizing a crude vegetable oil or a degummed vegetable oil, and removing organic acids therefrom, as well as in a process for making a refined edible vegetable oil wherein a crude vegetable oil is degummed, passed through the impregnated activated carbon, and subjected to steam distillation at reduced pressure. A novel method of preparing the MgO impregnated activated carbon has also been discovered.
    Type: Grant
    Filed: March 22, 1977
    Date of Patent: November 14, 1978
    Assignee: Merck & Co., Inc.
    Inventor: Rabindra K. Sinha
  • Patent number: 4125719
    Abstract: 1,3,5-s-Hexahydrotrisubstituted triazines exemplified by 1,3,5-tris(furfuryl)-1,3,5-hexahydro-s-triazines are useful as antimicrobial agents particularly when employed as a component of metal-working compositions subject to fungal and bacterial attack.
    Type: Grant
    Filed: August 1, 1977
    Date of Patent: November 14, 1978
    Assignee: Merck & Co., Inc.
    Inventors: Nathaniel Grier, Bruce E. Witzel
  • Patent number: 4123520
    Abstract: A vaccine against Group C meningococcal meningitis consisting of a polysaccharide of which at least 80% by weight has a molecular weight in excess of 1,000,000 daltons is prepared. The polysaccharide was isolated from Group C hexadecyl trimethylammonium bromide cell paste with 1.0M CaCl.sub.2 extraction and purified by phenol extraction, ultracentrifugation at 100,000 g. and ethanol fractionation (30%-45% v/v in ethanol).
    Type: Grant
    Filed: August 1, 1977
    Date of Patent: October 31, 1978
    Assignee: Merck & Co., Inc.
    Inventors: Arpi Hagopian, Dennis J. Carlo, Thomas H. Stoudt
  • Patent number: 4119779
    Abstract: 1,3,5-s-Hexahydrotrisubstituted triazines exemplified by 1,3,5-tris(tetrahydrofurfuryl)-1,3,5-hexahydro-s-triazines are useful as antimicrobial agents particularly when employed as a component of metal-working compositions subject to fungal and bacterial attack.
    Type: Grant
    Filed: May 11, 1977
    Date of Patent: October 10, 1978
    Assignee: Merck & Co., Inc.
    Inventors: Nathaniel Grier, Bruce E. Witzel
  • Patent number: 4100193
    Abstract: Novel dibicyclo [2.2.2] octyl dibicyclo [2.2.2] octenyl polyamines are useful antimicrobial agents, as well as algae inhibitors. They are especially useful as hard surface disinfectants and as additives to oil well drilling muds, injection brines and industrial water where bacterial control is desired.
    Type: Grant
    Filed: June 10, 1976
    Date of Patent: July 11, 1978
    Assignee: Merck & Co., Inc.
    Inventors: Nathaniel Grier, Richard A. Dybas, Robert A. Strelitz
  • Patent number: 4098726
    Abstract: Novel polymers having a linear backbone which is free from both branching and cross-linking, comprising quaternized nitrogen atoms linked to each other through trimethylene groups. By the term "linear backbone" is meant that the polymer has only acyclic groups, i. e. trimethylene, linking the nitrogen atoms in a single continuous chain; the polymer is free from "branching" when it has no repeating monomer units extending from the polymer backbone; and it is free from "cross-linking" when there is no joining of two linear backbones. These polymers are useful as antimicrobials, flocculating agents, antistatic agents, electroconductive agents for coating paper, chelating agents and bile acid binding agents, as well as in similar applications where their high charge to weight ratio and fully accessible nitrogen atoms can be employed. The polymers are obtained by the polymerization of dihydro-oxazine, reductive alkylation of the resulting polymer, followed by quaternization.
    Type: Grant
    Filed: April 1, 1977
    Date of Patent: July 4, 1978
    Assignee: Merck & Co., Inc.
    Inventors: Arthur F. Wagner, Nathaniel Grier, Tsung-Ying Shen