Patents Represented by Attorney Edwards Wildman Palmer LLP
  • Patent number: 8338150
    Abstract: Disclosed is a method for parallel delivery of agents to and/or into a cell structure, wherein at least two electrolyte-filled tubes are provided together with a counter electrode, the tubes being connected to a voltage or current generator, said agents being introduced into the electrolyte solution contained in the tubes, which are placed close to the cell structure, whereupon the agents are transported through the tubes to said cell structure and into the said structure through pores which have been formed by application of an electric field focused on the cell structure, resulting in electroporation of the cell structure. Also different applications of the method is disclosed, e.g. use of the method in order to transfer cell-impermeant solutes, such as drugs or genes, into the cell structure or out of the cell structure.
    Type: Grant
    Filed: June 9, 2008
    Date of Patent: December 25, 2012
    Assignee: Cellectricon AB
    Inventors: Owe Orwar, Mattias Karlsson, Kerstein Nolkrantz, Cecilia Farre
  • Patent number: 8338708
    Abstract: An electric junction box is provided having a receiving portion enabling a joint to be securely press-fitted into a joint, even if the outer diameter of the joint varies within a wide range. An electric junction box is comprised of a joint having electrical conduits that are electrically connected to each other at their terminals, and a cap disposed on the terminals, and a receiving portion which the joint is press-fitted into. The receiving portion comprises a recess having an inner surface facing an outer surface of the joint, and a rib projection disposed on the inner surface of the recess. The rib projection has a tapered portion inclined toward the bottom of the recess thus approximating the center portion of the bottom.
    Type: Grant
    Filed: October 27, 2009
    Date of Patent: December 25, 2012
    Assignee: Yazaki Corporation
    Inventors: Akemi Maebashi, Shigeharu Tsukui
  • Patent number: 8340717
    Abstract: In an embodiment, a mobile device is provided comprising a network interface and download controller. In an embodiment, the download controller is configured to check if a file to be downloaded can be handled by the mobile device and to transmit a download request to a further device if the mobile device cannot handle the file.
    Type: Grant
    Filed: December 4, 2008
    Date of Patent: December 25, 2012
    Assignee: Sony Ericsson Mobile Communications AB
    Inventor: Eskil Gunnar Ahlin
  • Patent number: 8338077
    Abstract: This invention relates to new photoacid generator compounds and photoresist compositions that comprise such compounds. In particular, the invention relates to photoacid generator compounds that comprise a multi cyclic lactone moiety.
    Type: Grant
    Filed: June 22, 2010
    Date of Patent: December 25, 2012
    Assignee: Rohm and Haas Electronic Materials LLC
    Inventors: Mingqi Li, Cheng-Bai Xu, Emad Aqad, Cong Liu
  • Patent number: 8338613
    Abstract: The invention relates to a process for the preparation of bidentate Schiff base catalysts containing a salicylaldimine-type ligand.
    Type: Grant
    Filed: September 17, 2009
    Date of Patent: December 25, 2012
    Assignee: RIMTEC Corporation
    Inventors: Renata Drozdzak, Naoki Nishioka
  • Patent number: 8338035
    Abstract: The present invention preferably provides a separator for a fuel cell, in which a strength reinforcing means is integrally formed in a region, which is not supported by a gasket, over the region from manifolds, through which reactant gases and coolant are supplied, to a reaction flow field, in which a reaction takes place, thus suitably preventing local deformation of the separator.
    Type: Grant
    Filed: November 20, 2009
    Date of Patent: December 25, 2012
    Assignees: Hyundai Motor Company, Kia Motors Corporation
    Inventors: Sang Mun Chin, Sae Hoon Kim, Yoo Chang Yang, Chul Ho Yim, Suk Min Baeck, Seong Il Heo
  • Patent number: 8337656
    Abstract: To provide a pressure-sensitive adhesive sheet which protects a ground, thin, fragile adherend from “warping” and which can be removed from the fragile adherend after the completion of backgrinding without damaging and contaminating the fragile adherend. The pressure-sensitive adhesive sheet 5 includes a base layer A, a pressure-sensitive adhesive layer A, a base layer B, and a pressure-sensitive adhesive layer B arranged in this order, in which: the base layer A has a product of its Young's modulus at 25° C. and its thickness of 1.0×105 to 4.0×105 N/m and a product of its Young's modulus at 80° C. and its thickness of 2.8×105 N/m or less; the pressure-sensitive adhesive layer A has a shear modulus at 80° C. of 0.2 MPa or less; the base layer B has a product of its Young's modulus at 25° C. and its thickness of smaller than that of the base layer A and has, upon 80° C.
    Type: Grant
    Filed: May 1, 2009
    Date of Patent: December 25, 2012
    Assignee: Nitto Denko Corporation
    Inventors: Akinori Nishio, Kazuyuki Kiuchi
  • Patent number: 8337797
    Abstract: According to the method for producing bis(fluorosulfonyl)imide of the present invention, first, an unreacted mixed liquid is prepared by mixing a first fluorosulfonic acid with urea in a condition free of a chemical reaction between the first fluorosulfonic acid and urea. Then, the unreacted mixed liquid is dripped into a heated second fluorosulfonic acid or a heated bis(fluorosulfonyl)imide, allowing a chemical reaction between fluorosulfonic acid and urea to proceed. In this method, generation of carbon dioxide gas and heat during the chemical reaction can be controlled.
    Type: Grant
    Filed: March 31, 2010
    Date of Patent: December 25, 2012
    Assignees: Mitsubishi Materials Corporation, Mitsubishi Materials Electronic Chemicals Co., Ltd.
    Inventors: Tsunetoshi Honda, Takeshi Kamiya
  • Patent number: 8338462
    Abstract: The present invention provides a compound having a superior acid secretion inhibitory effect and showing an antiulcer activity and the like. The present invention provides a compound represented by the formula (I) wherein R1 is a nitrogen-containing monocyclic heterocyclic group optionally condensed with a benzene ring or a heterocycle, the nitrogen-containing monocyclic heterocyclic group optionally condensed with a benzene ring or a heterocycle optionally has substituent(s), R2 is an optionally substituted C6-14 aryl group, an optionally substituted thienyl group or an optionally substituted pyridyl group, R3 and R4 are each a hydrogen atom, or one of R3 and R4 is a hydrogen atom and the other is an optionally substituted lower alkyl pup, an acyl group, a halogen atom, a cyano group or a nitro group, and R5 is an alkyl group or a salt thereof.
    Type: Grant
    Filed: June 8, 2011
    Date of Patent: December 25, 2012
    Assignee: Takeda Pharmaceuticals Company Limited
    Inventors: Masahiro Kajino, Atsushi Hasuoka, Haruyuki Nishida
  • Patent number: 8338591
    Abstract: The present invention provides compounds of Formula (I) or (II) salt form or prodrug thereof, wherein variables are defined herein, that are modulators of metalloproteases such as matrix metalloproteases (MMPs) and ADAMs. The compounds or compositions described herein can be used to treat diseases associated with metalloprotease activity including, for example, arthritis, cancer, cardiovascular disorders, skin disorders, inflammation or allergic conditions.
    Type: Grant
    Filed: May 6, 2005
    Date of Patent: December 25, 2012
    Assignee: Novartis International Pharmaceutical Ltd.
    Inventors: Taeyoung Yoon, Jun Yuan, Kyungae Lee, George D. Maynard, Nian Liu
  • Patent number: 8337606
    Abstract: Described is a new a solution comprising a phosphorous compound and a solderability-enhancing compound and its use in a process for increasing the solderability and corrosion resistance of a metal or metal alloy surface.
    Type: Grant
    Filed: July 10, 2008
    Date of Patent: December 25, 2012
    Assignee: Atotech Deutschland GmbH
    Inventor: Peter Kuhlkamp
  • Patent number: 8338425
    Abstract: This invention relates to novel 2-{6-[4-(2-hydroxy-ethyl)-piperazin-1-yl]-2-methyl-pyrimidin-4-ylamino}-thiazole-5-carboxylic acid (2-chloro-6-methyl-phenyl)-amide derivatives, and pharmaceutically acceptable acid addition salts thereof. The invention also provides compositions comprising a compound of this invention and the use of such compositions in methods of treating diseases and conditions beneficially treated by the inhibition of kinases including Src-kinase and Bcr-Abl kinase.
    Type: Grant
    Filed: December 9, 2008
    Date of Patent: December 25, 2012
    Assignee: Concert Pharmaceuticals, Inc.
    Inventor: Roger Tung
  • Patent number: 8338595
    Abstract: This invention relates to pyrrozolotriazine compounds, pharmaceutical compositions containing such compounds and the use of those compounds and compositions for the prevention and/or treatment of hyper-proliferative disorders and diseases associated with angiogenesis.
    Type: Grant
    Filed: July 20, 2009
    Date of Patent: December 25, 2012
    Assignee: Bayer HealthCare LLC
    Inventors: Julie A. Dixon, Catherine Brennan, Karl Miranda, Brent Chandler, Barton Phillips, Jianmei Fan, Michael Brands, Andrea McClure, Benjamin D. Jones, Wenlang Fu, Donald Bierer, Steven Magnuson, Harold C. E. Kluender
  • Patent number: 8340368
    Abstract: The present invention relates to a face detection system for a vehicle. At least one first lighting unit is configured to radiate infrared light onto a left side of a driver's face. At least one second lighting unit is configured to radiate infrared light onto a right side of the driver's face. An image capturing unit separately captures the driver's face onto which the infrared light is radiated from the first and second lighting units. A control unit acquires left and right images of the face from the image capturing unit, and obtains a difference image between the acquired left and right images, thus determining whether the driver is inattentive in looking ahead. The system stably performs the face detection function with no or less effect by external optical environments as well as reduced computational load.
    Type: Grant
    Filed: December 29, 2008
    Date of Patent: December 25, 2012
    Assignees: Hyundai Motor Company, Kia Motors Corporation
    Inventors: Byoung Joon Lee, Eui Yoon Chung
  • Patent number: 8337860
    Abstract: The invention is related to a dengue virus or chimeric dengue virus that contains a mutation in the 3? untranslated region (3?-UTR) comprising a ?30 mutation that removes the TL-2 homologous structure in each of the dengue virus serotypes 1, 2, 3, and 4, and nucleotides additional to the ?30 mutation deleted from the 3?-UTR that removes sequence in the 5? direction as far as the 5? boundary of the TL-3 homologous structure in each of the dengue virus serotypes 1, 2, 3, and 4, or a replacement of the 3?-UTR of a dengue virus of a first serotype with the 3?-UTR of a dengue virus of a second serotype, optionally containing the ?30 mutation and nucleotides additional to the ?30 mutation deleted from the 3?-UTR; and immunogenic compositions, methods of inducing an immune response, and methods of producing a dengue virus or chimeric dengue virus.
    Type: Grant
    Filed: August 15, 2007
    Date of Patent: December 25, 2012
    Assignee: The United States of America, as represented by the Secretary of the Department of Health & Human Services
    Inventors: Stephen S. Whitehead, Joseph E. Blaney, Brian R. Murphy
  • Patent number: 8338461
    Abstract: The present invention provides a compound having a superior acid secretion inhibitory effect and showing an antiulcer activity and the like. The present invention provides a compound represented by the formula (I) wherein R1 is a nitrogen-containing monocyclic heterocyclic group optionally condensed with a benzene ring or a heterocycle, the nitrogen-containing monocyclic heterocyclic group optionally condensed with a benzene ring or a heterocycle optionally has substituent(s), R2 is an optionally substituted C6-14 aryl group, an optionally substituted thienyl group or an optionally substituted pyridyl group, R3 and R4 are each a hydrogen atom, or one of R3 and R4 is a hydrogen atom and the other is an optionally substituted lower alkyl group, an acyl group, a halogen atom, a cyano group or a nitro group, and R5 is an alkyl group or a salt thereof.
    Type: Grant
    Filed: March 1, 2011
    Date of Patent: December 25, 2012
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Masahiro Kajino, Atsushi Hasuoka, Haruyuki Nishida
  • Patent number: 8336604
    Abstract: This manufacturing apparatus for a multi-channel tube having a plurality of parallel channels includes: a crucible; and a die set for forming the multi-channel tube from molten copper supplied from the crucible, the die set including: a hollow portion having an inner surface shaped like the profile of the multi-channel tube; punches which are inserted into the hollow portion from an inlet end of the hollow portion to define a space between the inner surface of the hollow portion and each of the punches; and a feed passage which is disposed between the crucible and the space, and configured to feed the molten copper from the crucible to the space, the molten copper being supplied from the crucible to the space within the die set through the feed passage to solidify as it passes through the hollow portion.
    Type: Grant
    Filed: December 14, 2007
    Date of Patent: December 25, 2012
    Assignees: CTA Technology (Proprietary) Limited, Mitsubishi Materials Corporation
    Inventors: David Machet, Antonio Rodrigues Da Cruz, Vladimir Shoilovich Ziserman, Kenichi Takagi
  • Patent number: 8337854
    Abstract: The present invention relates to a variant of a parent polypeptide comprising an Fc region, which variant binds an Fc gamma receptor (Fc?R) with lower affinity than the parent polypeptide and comprises a deletion of at least one amino acid in about position 100 to about position 150 in the Fc region and related nucleic acids, vectors, host cells and methods of producing the variant and methods for preventing or treating a disorder in a mammal.
    Type: Grant
    Filed: April 3, 2008
    Date of Patent: December 25, 2012
    Assignee: The United States of America, as represented by the Secretary, Department of Health & Human Services
    Inventors: Ana P. Goncalvez, Robert H. Purcell, Ching-Juh Lai
  • Patent number: 8339397
    Abstract: Appropriate shadowing processing is performed even if coordinate conversion calculation values of polygons have errors. A calculation section 5 performs hidden surface removal processing on normal polygons based on visual-point coordinates and depth values from a visual-point coordinate conversion processing unit 1, and updates a pixel memory 6 and a Z-buffer memory 7. Further, based on a comparison result of obtained depth values of each polygon and Z values stored in the Z-buffer memory 7, shadowing is performed only on a coordinate region positioned in front of back-facing shadow polygons and behind front-facing shadow polygons when seen from a visual point, and the pixel memory 6 is updated. As a result, even if coordinate conversion calculation values in graphic data on polygons have errors, an edge portion of the shadow polygons which is not intended to be shadowed is not shadowed.
    Type: Grant
    Filed: March 9, 2004
    Date of Patent: December 25, 2012
    Assignee: Sharp Kabushiki Kaisha
    Inventor: Yasuyuki Kii
  • Patent number: 8341670
    Abstract: A method and a system for providing application service are disclosed. The method of providing application service in a digital data broadcasting system coupled to at least one broadcasting terminal through a network includes generating a preview contents by using first data combined with an application for data broadcasting service, wherein the preview contents has second data provided when a user requests the application service, and transmitting the generated preview contents to the broadcasting terminal. Here, the broadcasting terminal outputs the preview contents before data broadcasting standby time. Accordingly, useful information may be provided to the user before the application is executed.
    Type: Grant
    Filed: September 10, 2008
    Date of Patent: December 25, 2012
    Assignee: Alticast Corporation
    Inventors: Jin-Won Kim, Hwan-Hyo Park