Patents Represented by Attorney, Agent or Law Firm Elias J Lambiris
  • Patent number: 8288144
    Abstract: The present invention relates to pectate lyase variants exhibiting alterations relative to a parent enzyme exhibiting pectate lyase activity as its major enzymatic activity; to a method of producing such enzymes; and to methods for using such enzymes in the textile, detergent and cellulose fiber processing industries. Compared to the parent enzyme, the pectate lyase variants of the present invention exhibit improved stability in detergents.
    Type: Grant
    Filed: June 10, 2009
    Date of Patent: October 16, 2012
    Assignee: Novozymes A/S
    Inventors: Sanne Schroder Glad, Carsten Andersen, Torben Vedel Borchert, Katja Salomon Johansen, Henrik Frisner, Mads Eskelund Bjornvad, Thomas Thisted
  • Patent number: 7893196
    Abstract: The present invention relates to isolated polypeptides having antimicrobial activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides.
    Type: Grant
    Filed: November 19, 2005
    Date of Patent: February 22, 2011
    Assignee: Novozymes Aderium Biotech A/S
    Inventors: Dorotea Raventos Segura, Per Holse Mygind, Mogens Trier Hansen, Marianne Vind Soerensen, Dorthe Sandvang
  • Patent number: 7892808
    Abstract: The invention relates to a novel 3D structure determined for a Nocardiopsis protease, as well as to variants of parent protease homologous to Nocardiopsis proteases, preferably of improved thermostability and/or with an altered temperature activity profile. The invention also relates to DNA sequences encoding such variants, their production in a recombinant host cell, as well as methods of using the variants, in particular within the field of animal feed and detergents. The invention further relates to methods of generating and preparing protease variants having different properties.
    Type: Grant
    Filed: October 8, 2004
    Date of Patent: February 22, 2011
    Assignee: Norozymes A/S
    Inventors: Leonardo De Maria, Carsten Andersen, Lars Lehmann Hylling Christensen, Soren Flensted Lassen, Peter Rahbek Ostergaard
  • Patent number: 7883711
    Abstract: The present invention relates to the use of polypeptides related to a Bacillus licheniformis polypeptide (amino acids 1-85 of SEQ ID NO: 2) as antimicrobial agents, for example in pharmaceutical applications, including veterinary applications, as well as for preservation, cleaning and disinfection of various surfaces, objects and substances. The polypeptides may in particular be used to treat textiles or laundry, e.g., in detergents, for reducing microbes on textile or laundry, and/or for odor reduction. The invention also relates to use of Bacillus strains producing these polypeptides as antimicrobial agents. Examples of microorganism inhibited by Lento are Gram positive bacterial strains, such as Bacillus cereus, and various species of Corynebacterium, Enterococcus, Micrococcus, Streptococcus, and Staphylococcus.
    Type: Grant
    Filed: March 20, 2007
    Date of Patent: February 8, 2011
    Assignee: Novozymes A/S
    Inventors: Erik Gormsen, Debbie Yaver
  • Patent number: 7871800
    Abstract: The present invention relates to polypeptides having glucoamylase activity and isolated polynucleotides encoding said polypeptides preferably derived from a strain of Peniphora rufomarginata. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides. The invention also relates to the composition comprising a glucoamylase of the invention as well as the use such compositions for starch conversion processes, brewing, including processes for producing fermentation products or syrups.
    Type: Grant
    Filed: April 13, 2007
    Date of Patent: January 18, 2011
    Assignees: Novozymes A/S, Novozymes North America, Inc.
    Inventors: Sara Landvik, Jiyin Liu, Carsten Horslev Hansen, Chee Leong Soong, Jeppe Wegener Tams
  • Patent number: 7867745
    Abstract: The present invention relates to isolated polypeptides having alpha-glucuronidase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.
    Type: Grant
    Filed: November 26, 2008
    Date of Patent: January 11, 2011
    Assignee: Novozymes A/S
    Inventors: Eva H. Hansen, Domique A. Skovland, Hanne R. Soerensen
  • Patent number: 7867744
    Abstract: The present invention relates to polypeptides having cellobiohydrolase II activity and polynucleotides having a nucleotide sequence which encodes for the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the nucleic acid constructs as well as methods for producing and using the polypeptides.
    Type: Grant
    Filed: December 18, 2007
    Date of Patent: January 11, 2011
    Assignee: Novozymes A/S
    Inventors: Wenping Wu, Lene Lange, Dominique Aubert Skovlund, Ye Liu
  • Patent number: 7833771
    Abstract: The present invention relates to polypeptides having alpha-amylase activity and polynucleotides having a nucleotide sequence which encodes for the polypeptides. The invention also relates to a polypeptide having carbohydrate-binding affinity and polynucleotides having a nucleotide sequence which encodes for the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the nucleic acid constructs as well as methods for producing and using the polypeptides.
    Type: Grant
    Filed: December 5, 2007
    Date of Patent: November 16, 2010
    Assignees: Novozymes A/S, Novozymes North America Inc
    Inventors: Tine Hoff, Carsten Andersen, Tina Spendler, Sven Pedersen, Anders Vikso-Nielsen, Thomas Schafer, Jiyin Liu
  • Patent number: 7833967
    Abstract: The present invention relates to polypeptides having antimicrobial activity and polynucleotides having a nucleotide sequence which encodes for the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the nucleic acid constructs as well as methods for producing and using the polypeptides.
    Type: Grant
    Filed: June 21, 2007
    Date of Patent: November 16, 2010
    Assignee: Novozymesadenium BioTech A/S
    Inventor: Hans-Henrik Kristensen Hogenhaug
  • Patent number: 7833772
    Abstract: The invention relates to a variant of a parent fungal glucoamylase, which exhibits improved thermal stability and/or increased specific activity using saccharide substrates.
    Type: Grant
    Filed: September 21, 2006
    Date of Patent: November 16, 2010
    Assignee: Novozymes A/S
    Inventors: Bjarne Roenfeldt Nielsen, Allan Svendsen, Henrik Pedersen, Jesper Vind, Hanne Vang Hendriksen, Torben Peter Frandsen
  • Patent number: 7829524
    Abstract: The present invention relates to polypeptides having antimicrobial activity and polynucleotides having a nucleotide sequence which encodes for the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the nucleic acid constructs as well as methods for producing and using the polypeptides.
    Type: Grant
    Filed: June 10, 2004
    Date of Patent: November 9, 2010
    Assignee: Novozymes Adenium Biotech A/S
    Inventors: Dorotea Raventos Segura, Per Holse Mygind, Hans-Henrik Kristensen Hoegenhaug, Alessandro Tossi
  • Patent number: 7727756
    Abstract: The present invention relates to methods for producing variants of a parent JP170 subtilase and of a parent BPN? subtilase and to JP170 and BPN? variants having altered properties as compared to the parent JP170/BPN? subtilase.
    Type: Grant
    Filed: March 22, 2004
    Date of Patent: June 1, 2010
    Assignee: Novozymes A/S
    Inventors: Allan Svendsen, Stefan Minning
  • Patent number: 7666650
    Abstract: The inventors have identified amylases in fungal strains of Valsaria and found that the amylase can increase the shelf life of baked products. Particularly, the novel amylase in combination with a maltogenic amylase further improves the softness of bread crumb without having detrimental effects on elasticity.
    Type: Grant
    Filed: December 22, 2004
    Date of Patent: February 23, 2010
    Assignee: NovoZymes A/S
    Inventors: Liu Ye, Tang Lan, Tina Spendler, Mary Ann Stringer
  • Patent number: 7622287
    Abstract: The present invention relates to a method of designing laccase mutants with increased oxidation potential and/or changed pH optimum and/or altered mediator pathway and/or altered O2/OH?-pathway, which method is based on the hitherto unknown three dimensional structure of laccases, wherein the parent laccase is a Myceliophthora thermophila, Polyporus pinsitus, or Coprinus cinereus laccase.
    Type: Grant
    Filed: December 7, 2000
    Date of Patent: November 24, 2009
    Assignee: Novozymes A/S
    Inventors: Allan Svendsen, Feng Xu
  • Patent number: 7588926
    Abstract: The invention relates to a novel class of serine proteases of peptidase family S2A or S1E that are stable in the presence of copper (Cu2+) and/or inhibited by copper only to a limited extent. Structural features of potential relevance for this effect are also disclosed. This class of proteases includes proteases derived from Brachysporiella gayana, Nocardiopsis dassonvillei subsp. dassonvillei, Nocardiopsis prasina, and Nocardiopsis alba. The invention also relates to DNA encoding such proteases and the expression thereof in a host cell, animal and plant cells, as well as to the use thereof in animal feed and in detergents. In particular, the invention relates to animal feed and animal feed additives, such as premix, incorporating these proteases together with 1-500 ppm Cu (in-feed-concentration).
    Type: Grant
    Filed: February 9, 2004
    Date of Patent: September 15, 2009
    Assignee: Novozymes A/S
    Inventors: Peter Rahbek Oestergaard, Leonardo De Maria
  • Patent number: 7582458
    Abstract: The present invention provides improved fermentation processes, including for use in an ethanol production process. The improved fermentation processes include applying at least one fatty acid oxidizing enzyme (especially a lipoxygenase) in a fermentation process. The improved fermentation process may also involve the addition of various additional enzymes and growth stimulators for the fermenting microorganisms, including vitamins and mineral.
    Type: Grant
    Filed: December 9, 2005
    Date of Patent: September 1, 2009
    Assignee: Novozymes North America, Inc.
    Inventor: Varvara Grichko
  • Patent number: 7575769
    Abstract: The present invention is directed to mold control and extended shelf life methods and compositions for preparing edible dough-based products, such as, for example, breads, by treating the surface of the dough used to prepare the edible product with at least one preservative and at least one pH adjusting agent prior to or during baking. The present invention is also directed to methods and compositions for preparing edible dough-based products, such as, for example, breads, by treating the surface of the dough used to prepare the edible product with a at least one pH adjusting agent prior to or during baking.
    Type: Grant
    Filed: September 15, 2004
    Date of Patent: August 18, 2009
    Assignees: Innovative Cereal System LLC, Bakery Technology Center BV, Novozymes A/S, Novozymes North America, Inc.
    Inventors: Paul David de Levita, Marcellus Gerardus Sturkenboom, Antonius Adrianus Gerardus van Duijnhoven, Gregory Reigh Worthington, Hans Peder Heldt-Hansen, John Slade
  • Patent number: 7537922
    Abstract: The present invention relates to isolated proteases of the RP-II type and variants of RP-II proteases exhibiting improved properties in comparison to the parent RP-II protease, DNA constructs and vectors coding for the expression of said proteases and variants, host cells capable of expressing the proteases and variants from the DNA constructs, as well as a method of producing them by cultivating said host cells. The proteases may advantageously be used as constituents in detergent compositions and additives, optionally in combination with other enzymes such as proteases, lipases, cellulases, amylases, peroxidases or oxidases.
    Type: Grant
    Filed: February 27, 2007
    Date of Patent: May 26, 2009
    Assignee: Novozymes A/S
    Inventors: Mads Norregaard-Madsen, Peter Rahbek Østergaard, Claus Bo Voge Christensen, Søren Flensted Lassen
  • Patent number: 7507569
    Abstract: Novel subtilases having an improved wash performance on egg stains are disclosed. These subtilases are useful exhibiting excellent or improved wash performance on egg stains when used in e.g. cleaning or detergent compositions, such as laundry detergent compositions and dish wash compositions, including automatic dish wash compositions.
    Type: Grant
    Filed: May 6, 2004
    Date of Patent: March 24, 2009
    Assignees: Novozymes A/S, Maxygen Inc.
    Inventors: Stefan Minning, Jurgen Carsten Franz Knotzel, Niels Henrik Sorensen, Jon E. Ness, Mark D. Welch, Lorraine J. Giver, Joel Cherry, Torben Vedel Borchert, Jeremy Minshull
  • Patent number: 7504375
    Abstract: The present invention relates to polypeptides having antimicrobial activity and polynucleotides having a nucleotide sequence which encodes for the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the nucleic acid constructs as well as methods for producing and using the polypeptides.
    Type: Grant
    Filed: August 22, 2006
    Date of Patent: March 17, 2009
    Assignee: Novozymes A/S
    Inventors: Hans-Henrik Kristensen Hogenhaug, Per Holse Mygind, Dorotea Raventos Segura, Olivier Taboureau, Carsten Peter Sonksen