Abstract: A two layered cleansing tablet for the self-acting cleansing of dentures. The layers of the tablet disintegrate at controlled rates so that denture cleansing action is made more efficient and effective compared to single layered tablet structures. The present tablet employs sulfonic acid in the tablet layer which disintegrates in a first stage cleansing step and further employs ethylene diamine tetraacetate in both tablet layers. Improved denture cleansing action is achieved even with no increase in the total amount of active agents employed in a tablet.
Type:
Grant
Filed:
April 3, 1979
Date of Patent:
March 17, 1981
Inventors:
Werner Krisp, Rainer Malkowski, Mira Reuss
Abstract: New 4-hydroxy-3-(substitutedmethyl)benzeneacetic acids have been prepared which are useful as starting materials in the preparation of cephalosporin and penicillin derivatives.
Abstract: A composition for detection of the presence of mercury or mercury vapor comprises a formulation of cuprous iodide or silver iodide in combination with powdered elemental sulfur.
Abstract: Novel halomethyl derivatives of amines of the following general structure ##STR1## wherein Y is FCH.sub.2 --, F.sub.2 CH-- or F.sub.3 C--; R is hydrogen, alkylcarbonyl wherein the alkyl moiety has from 1 to 4 carbon atoms and is straight or branched, alkoxycarbonyl wherein the alkoxy moiety has from 1 to 4 carbon atoms and is straight or branched or ##STR2## wherein R.sub.3 is hydrogen, a straight or branched lower alkyl group of from 1 to 4 carbon atoms, benzyl or p-hydroxybenzyl; each of R.sub.1 and R.sub.2 is hydrogen, or a straight or branched lower alkyl group of from 1 to 4 carbon atoms and may be the same or different or R.sub.1 is hydrogen and R.sub.2 is fluorine; and pharmaceutically acceptable salts and individual optical isomers thereof.
Abstract: This invention is to the compound 5-[2-[[3-(1,3-benzodioxol-5-yl)-1-methylpropyl]amino]-1-hydroxyethyl]-2-me thoxybenzamide having the formula, ##STR1## pharmaceutically acceptable salts and individual optical isomers thereof, pharmaceutical compositions comprising as the active ingredient the compound of Formula 1 or salts or isomers thereof and the use of said compound, or salt or isomer thereof or pharmaceutical composition comprising same in the treatment of hypertension.
Abstract: A fast-acting (3-5 min.) denture-cleansing tablet for use in aqueous solutions to automatically clean dentures is comprised of a mixture containing gas-forming materials, organic and inorganic calcium bonding materials, oxidizing materials, surfactant materials, carriers, lubricants and flavoring materials. Fast cleansing action and short decomposition times are obtained by including amidosulfonic acid, ethylene diamine tetraacetic acid, dialkyl thiourea, and a non-ionogenic fluorochemical material in an amount sufficient to achieve a pH in a 1% solution of such formulation in water of 6.3 to 6.5.
Abstract: Therapeutic antihypertensive compositions containing N-(2,6-dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine and N-(2-chloroethyl)-N-(1-methyl-2-phenoxyethyl)benzenemethanamine or their non-toxic, pharmaceutically acceptable salts are described as well as a method of reducing blood pressure in mammals.
Abstract: A spill of hydrofluoric acid is controlled and cleaned up by being treated with a composition comprising an aqueous solution of calcium acetate and applying to the resulting precipitate an activated composition of powdered magnesia and an appropriate normally solid pH indicator.
Abstract: This invention relates to a novel method for combatting heavy metal poisoning which comprises administering a compound of the formula: ##STR1## wherein Z is C.dbd.C, O, S, NH; R is hydrogen, methyl, ethyl, hydroxy, methoxy, ethoxy, chlorine, bromine, fluorine, iodine or trifluoromethyl; and n is 1, 2 or 3.
Type:
Grant
Filed:
March 2, 1979
Date of Patent:
July 1, 1980
Assignee:
Merrell Toraude et Compagnie
Inventors:
Eugene L. Giroux, Nellikunja J. Prakash, Paul J. Schechter
Abstract: This invention relates to a novel method for enhancing zinc serum and tissue concentrations which comprises administering a compound of the formula: ##STR1## wherein Z is C.dbd.C, O, S, NH; R is hydrogen, methyl, ethyl, hydroxy, methoxy, ethoxy, chlorine, bromine, fluorine, iodine or trifluoromethyl; and n is 1, 2 or 3.
Type:
Grant
Filed:
March 2, 1979
Date of Patent:
July 1, 1980
Assignee:
Merrell Toraude et Compagnie
Inventors:
Eugene L. Giroux, Nellikunja J. Prakash, Paul J. Schechter