Abstract: The present invention discloses the use of a mutant Leishmania as a suicidal vaccine wherein the mutant Leishmania is responsive to external signals to become porphyric and commit suicidal cytolysis. The mutant can be selected from natural Leishmania species or constructed by genetic engineering.

Abstract: A synthetic-resin-made linear slide fastener has a top end stop and a bottom end stop. A coil-like or zigzag-like linear fastener element row (3) of synthetic resin is mounted on a side edge of a fastener tape (4), and then a rod-like body (6) is inserted into a coupling space portion (13) in a rear side of coupling heads (10) of plural fastener elements at a terminal end of the fastener element row (3) and attached thereto. Alternatively, a curved sheet-like body (7) is attached such that the sheet-like body surrounds and covers surfaces of the coupling heads (10), leg portions (11) and connecting portions (12) and thereafter, the rod-like body or the sheet-like body is fused with fastener elements (3) by ultrasonic welding so as to form an end stop (14) as the top end stop (15) or the bottom stop end (16).

Abstract: In a motor drive injection unit and a motor drive injection method, which can obtain an injection speed suitable for a molding material having fast solidifying speed as well as can securely carry out pressure keeping for a predetermined period of time while making a position of an injection piston unmovable after injection and filling are completed, a molding material in a cylinder is injected into a metal mold by converting a rotational motion of an electric servo motor into a reciprocating motion of an injection piston in the cylinder through a plunger with a ball screw, a surge pressure control means is provided for placing the injection piston in the cylinder in an unmovable state when at least a predetermined amount of a load is applied to the injection piston by the molding material in the cylinder, the surge pressure control means includes a combination of rotation control means of the electric servo motor and an upward movement suppression mechanism of the injection piston, and further, an injection s

Abstract: A slider for a slide fastener comprises: a slide body (1) including an upper wing (15) and a pull tab (2) having a pintle (6); the slider body (1) comprising: a pull-tab-attaching yoke (18) mounted on the upper wing (15) in cantilevered manner, having an indentation (46) formed therein for receiving the pintle (6) directly or indirectly, and defining with the upper wing (15) a gap (47); and a closing member (20) movably mounted on the slider body (1) so as to close and open the gap (47). The pull tab (2) further includes a pull tab body (4) and a pair of opposed protuberant walls (5) provided on the lower side of the pull tab body (4). The pintle (6) extends between the opposed protuberant walls (5) to connect them. At least one of the ends of the opposed protuberant walls (5) is open to provide an open space (7).

Abstract: A slider having an automatic stopper capable of accommodating a drooping piece of a leaf spring in a front face of a guide post of the slider and protecting it. In a body of the slider, upper and lower blades are connected via the guide post, and a groove portion which is open continuously in a vertical direction is provided at the front face of the guide post is provided. The drooping piece formed by bending an end of the leaf spring of an automatic stop mechanism disposed on a top face of the upper blade is engaged and accommodated within the groove portion and a projecting portion projecting forward is provided at a bottom end of the groove portion. The projecting portion is located below the drooping piece to protect a front end of the drooping piece and formed into a shape preventing a pointed object from being inserted between the drooping piece and the projecting portion, thereby protecting the slider from being destroyed intentionally.

Abstract: A reverse-separating device for a slide fastener, comprises a retainer pin 5, a separable pin 6 both made of metal and a reverse-separating slider 3. Each of the retainer pin 5 and the separable pin 6 is of a U-shaped cross-section and has a slit 18 formed along its front edge. At the lower end of the slit 18, the retainer pin 5 projects rearward beyond the slit 18 to thus provide a loop-like stopper 22 for engagement with the flange 31 of the reverse-separating slider 3. Once the retainer pin 5 is inserted into the reverse-separating slider 3, the retainer pin 5 is firmly retained by three parts of the reverse-separating slider 3. The separable pin 6 has a projecting ledge 28 formed on the upper end the projecting fin 27 so as to project laterally therefrom. The projecting ledge 28 of the separable pin 6 is adapted to abut against the upper end of the projecting fin 25 of the retainer pin 5 and thus prevent the separable pin 6 from moving further into the reverse-separating slider 3.

Abstract: The present invention is directed to compositions and methods to modulate inflammatory and immune responses in a subject, which includes immune activation and inhibiting inflammatory responses, by modulating the regeneration and tolerance factor (RTF).

Abstract: This invention relates to a slider for a slide fastener with an automatic stopper comprising front and rear mounting pillars of a slider body and a pawl body open to the rear mounting pillar and having a concave portion for accommodating a shaft portion of a pull wherein a gap portion allowing the shaft portion to pass through is formed in the concave portion by disposing the rear mounting pillar in a fitting guide groove in the slider body slidably in back and forth directions, and the shaft portion is prevented from slipping out of the concave portion through the gap portion when a pull holding body for covering the slider body is engaged with the front and rear mounting pillars, whereby simplifying a slider body's structure, an attachment structure of the pull and manufacturing procedure, and reducing a manufacturing cost while securing a stable/excellent automatic stopper function.

Abstract: A fiber-made surface fastener having on its back a covering of soft fiber yarns excellent in softness and in a function and durability as a surface fastener and including a multiplicity of engaging elements woven or knitted simultaneously with weaving or knitting of a substrate woven or knitted fabric (10) and projecting from a surface of the same woven or knitted fabric (10). Warp yarns (11 to 17, 111, 114) of the substrate woven or knitted fabric (10) contain finished yarns (15, 114) partially. The finished yarns (15, 114) are woven or knitted into the substrate woven or knitted fabric (10) such that the yarn floating from a rear surface of the same substrate woven or knitted fabric (10) and a substantially entire surface of the rear surface of the substrate woven or knitted fabric (10, 110) is covered with the same finished yarns (15, 114). Preferably, these finished yarns (15, 114) are bulky finished yarns composed of multifilaments.

Abstract: The fastening member removing force measuring device according to the present invention includes a holding unit (300) for holding and pressing a fabric (953) around a snap member (921), a restricting unit for restricting the snap member (921), and a tensile force measuring unit for pulling the restricting unit away from the fabric (953) and measuring a tensile force. The holding unit (300) includes a die (420) for mounting thereon the fabric 953, and a fabric presser unit (500) for holding the fabric (953) placed on the die (420) together with the die (420).

Abstract: A buckle including a pair of members (4, 5) coupled to or separated from each other. The buckle includes a socket (10) and a plug (30) capable of being inserted into the socket and hooked in the socket in the state where the plug is inserted into a prespecified position. The socket is attached to a one member (5) in the pair. The plug has a pull section (33) in the direction intersectional to the plug inserting direction, and a mounting section (37) with the other member mounted thereon is provided on the pull section (33).

Abstract: There are provided left and right gripper devices for holding left and right tip side portions of a slide fastener chain, transferring the fastener chain in a longitudinal direction (an X-axis direction) and opening and closing the left and right tip side portions in a Y-axis direction orthogonal to the X-axis direction based on a command sent from operation control means. There is provided an electric motor for controllably driving the left and right gripper devices in the X-Y axis direction based on a command sent from a numeric control section of the operation control means in the X-Y axis direction of the gripper devices. A slider can be automatically inserted by only a specified operation using a single device without preparing a special device for all types of fastener chains and sliders and requiring a time for a considerable reconstruction.

Abstract: A sheet attaching instrument (10) that includes an instrument body (11) and an attachment member (12), in which at least one engaging hole (50) is provided with a fall-stop (58) that can hold an attachment projection (30) in an area between an inserting section (51) and a holding section (52), and at least one peripheral edge of a pair of lateral side areas extending from the inserting section (51) to the holding section (52) through the fall-stop (58) is provided with a bridge (54) of which middle section is elastically deformable.

Abstract: An object of the invention is to provide a blade preferable for being mounted on various kinds of work machines, particularly work machines for digging, carrying of soil and leveling, in which increase in a quantity of soil per tractional force is achieved with a simple structure to reduce consumption horsepower and increase fuel consumption efficiency thereby leading to low cost. A blade comprises a central front face section having a linear first cutting edge at a bottom end thereof, a jointed front face section having a second cutting edge which continues from the first cutting edge and extends backward in an expanding manner at a predetermined angle, and an end front face section having a third cutting edge which continues from the second cutting edge and extended forward in an expanding manner at a predetermined angle.

Abstract: A top end stop of a slide fastener is attached to fastener stringers on a box pin side, and has a first side face opposing a guide column of a slider and a second side face on an opposite side. The first side face has first and second opposing side faces intersecting at an angle of 140° to 150°, and an interval A between the first opposing side face and the second side face being larger than a width C of an element aisle of the slider. An interval B between the second opposing side face and the second side face being equal to or smaller than the width C. A cut-out is provided as a stopper at a position on the second side face at a width E from the first opposing side face.

Abstract: The invention relates to a support structure comprising a support assembly that is supported by legs. The support assembly can be pivoted around a pivoting axis (4) relative to the legs from a position of use to a rest position and can be blocked from pivoting in the position of use by a fixing member. In an advantageous improvement of such a structure, the captivation member is configured as a latch (5) that engages, in the position of use, with a wedge-type blocking surface (8) by means of a spring force, thereby forcing it against a blocking shoulder (9,9?).

Abstract: The present invention provides a balloon anchor including a spool having opposing sides, a pair of flanges, one flange extending from each opposing side of the spool, at least one of the flanges having a cutout section, the cutout section having a first side and a second side; and a hook extending from the second side of the cutout section.

Abstract: An operation unit is provided with an engine operation box storing a control operation portion controlling an opening degree of a throttle valve and a start switch terminal connected to a start motor; a throttle operating lever for controlling the opening degree from an idle position to a full-open position; and a start switch connecting and disconnecting the start switch terminal, wherein the throttle operating lever has a switch shielding portion which enables to operate the start switch without an interference between the throttle operating lever and an operating portion of the start switch when the throttle operating lever is at an idle position, and disables to operate the start switch by shielding at least a part of the operating portion of the start switch by means of a part of the throttle operating lever when the throttle operating lever is operated to be apart from the idle position.