Abstract: A spinal disc annulus repair stent for repair and reconstruction of the spinal disc wall (annulus) after surgical invasion or pathologic rupture, which may incorporate suture closure or other means of stent insertion and fixation, designed to reduce the failure rate of conventional surgical procedures on the spinal discs. In an illustrative embodiment, the design of the spinal disc annulus stent advantageously allows ingrowth of normal cells of healing in an enhanced fashion strengthening the normal reparative process.

Abstract: The present invention concerns methods and compositions of use for treatment of Alzheimer's Disease (AD). In certain embodiments, the methods concern preparation of phage-display single chain antibody libraries and screening against amyloid-beta (A?) protein or peptide. Anti-A? antibodies are selected and sequenced. In certain embodiments, synthetic A? binding peptides are designed and prepared, using portions of the anti-A? antibody sequences. The antibodies and peptides are of use for treatment of AF or for treatment of individuals at risk of developing AD. Compositions comprising anti-A? antibodies or A? binding peptides are also disclosed.

Abstract: Embodiments of methods for pipeline rehabilitation include deploying a tubular liner along an inside of a pipeline, deflating the tubular liner to form a trough, and injecting grout into the pipeline by injecting grout into the trough. Other embodiments include deploying a tubular liner along an inside of a pipeline, inserting a first swab into the front end of the pipeline, the first swab having a core hole, placing the tubular liner through the core hole, injecting grout into the pipeline between the tubular liner and the inside of the pipeline, and advancing a second swab through the tubular liner to distribute the grout between the tubular liner and the pipeline and to advance the first swab ahead of the second swab from the front end to the back end of the pipeline.

Abstract: An embodiment includes a main lead assembly having a proximal portion adapted for connection to a device and a distal portion adapted for placement in a coronary sinus, the distal portion terminating in a distal end for placement proximal a left ventricle. Additionally, the main lead assembly includes a left ventricular electrode located at its distal end which is adapted to deliver cardiac resynchronization therapy to reduce ventricular wall stress. The main lead assembly also includes a fat pad electrode disposed along the main lead assembly a distance from the distal end to position the fat pad electrode proximal to at least one parasympathetic ganglia located in a fat pad bounded by an inferior vena cava and a left atrium. The fat pad electrode is adapted to stimulate the parasympathetic ganglia to reduce ventricular wall stress.

Abstract: An adjustable reclining chair including a seat configured to support a user, a chair back, a base and a control mechanism mounted on the base. The control mechanism coupling the chair back to the seat with the chair back located generally adjacent to the user's back when the user is seated upon the seat. The control mechanism including a resistance adjustment mechanism for varying the control mechanism's resistance to a reclining force applied by the user to the chair back in order to move the chair back rearward from an upright position. The resistance adjustment mechanism activated by the weight of the user when seated in the chair, such that easy adjustment of the resistance is facilitated with the chair in an upright position. The resistance adjustment mechanism including a resilient member placed under a load during reclining of the chair to provide resistance to the reclining force.

Abstract: An integrated lead flexure for a disk drive head suspension and method for making the flexure. The flexure includes a spring metal layer, a dielectric layer over the spring metal layer, and a plurality of conductive leads on the dielectric layer. The spring metal layer has a first surface, and the dielectric layer has a first surface opposite the spring metal layer first surface, and a plurality of troughs in least a portion of the dielectric layer. At least some of the leads are disposed in a respective dielectric layer trough.

Abstract: This document discusses, among other things, a lead assembly including a lead body, at least one conductor extending through the lead body, and a covering having varied material properties. In an example, the covering is made by forming pieces of material having varied material properties. In another example, the covering is made by varying parameters such as heat or tension during wrapping of a piece of material onto a lead assembly.

Abstract: A method for manufacturing an integrated lead suspension component. One or more first conductive ground planes are formed on a stainless steel base layer. One or more second conductive ground planes, including portions on the surface of the first conductive ground planes, are formed at void portions and backed portions of the stainless steel base layer. The material of the second conductive ground planes is non-reactive to a first etchant. An insulating layer is formed on the second ground planes on the side opposite the stainless steel base layer and on the stainless steel base layer. Traces are formed on the insulating layer. Voids are formed in void portions of the stainless steel base layer using the first etchant and the second conductive ground planes at the void portions as etch stops.

Abstract: Head suspension offset structures and methods of manufacture. The offset structure includes an offset extending out of a plane of a surface on which it is formed and a plurality of elongated voids and elongated links surrounding the offset. The links extend between the offset and the surface in both radial and circumferential direction. At least a portion of the elongated links and voids extend out of the plane of the surface, minimizing stretching and thinning of the material on and around the offset, and enhancing the integrity of the structure. The offset structure can be formed using conventional manufacturing processes.

Abstract: A cleaning composition for removing soils includes an alkyl vinyl ether-maleic acid copolymer and at least one component selected from the group consisting of sodium carbonate and sodium hydroxide. The composition contains less than about 10% by weight of at least one component selected from the group consisting of phosphorous-containing components and aminocarboxylates.

Abstract: The present invention provides methods and devices for annulus disc repair with and without the use of a patch or stent. The methods and devices are particularly suited to the repair and/or reconstruction of the spinal disc wall (annulus) after surgical invasion or pathologic rupture, with reduced failure rate as compared to conventional surgical procedures.

Abstract: An apparatus for performing a minimally-invasive surgical procedure in the vagus nerve region includes a cannula, an endoscopic dissection tool and a cradle assembly slideably disposed in a cannula lumen. The cradle assembly includes a C-ring, an electrode cuff disposed over an exterior surface of the C-ring, and a deployment device. The electrode cuff is adapted to wrap around the target nerve region or nerve branch to be stimulated when deployed from the C-ring using the deployment device. A method of performing a minimally invasive surgical procedure is also described.

Abstract: A cardiac constraint jacket is formed of flexible material defining a volume between an open upper end and a lower end. The jacket is dimensioned for an apex of a patient's heart to be inserted into the volume through the open upper end and for the jacket to be slipped over the heart. A delivery device is used to place the jacket on the heart. The delivery device includes a plurality of attachment locations. Each of the attachment locations is releasably secured to separate positions surrounding a periphery of the open upper end of the jacket. The delivery device also includes a control arrangement which is selectively movable between an open position and a closed position. The control arrangement is connected to the attachment locations such that the attachment locations are in a compact array urging the open upper end of the jacket into a collapsed configuration when the control member is in the closed position.

Abstract: The present invention is directed to kit or assembly of hand-held jewelry tools. The kit includes a least one pair of handles and one or more pairs of interchangeable jaws. Each set of jaws when attached to the pair of handles is adapted to perform a particular jewelry task. Because the kit includes a variety of interchangeable sets of jaws, it is possible to perform many different jewelry making tasks using the present kit.

Abstract: A lower back orthosis bandage includes a middle piece having a first flat end and a second flat end, a first end piece having a mouth-like end and a second end piece having a mouth-like end. The first end piece is releasably connected to the first flat end of the middle piece by the mouth-like end of the first end piece. The second end piece is releasably connected to the second flat end of the middle piece by the mouth-like end of the second end piece. The first end piece and the second end piece are connectable to each other to close the bandage.

Abstract: The present invention provides a functionally dry warm mix asphalt binder composition modified with lubricating agents or additives that can be mixed with aggregate and compacted at temperatures substantially below asphalt binder compositions that do not contain the disclosed lubricating additives.

Abstract: A medical system includes an implantable sensor; and a medical device having a communication link with the sensor. The medical device further including a controller, wherein operating parameters for controlling sampling of a physiological characteristic or other parameter by the implantable sensor are calculated by the controller and communicated to the sensor dynamically.

Abstract: An integrated lead head suspension flexure including a plurality of integrated leads each including at least one lead portion unbacked by the flexure spring metal layer and configured to be substantially inline with the general plane of the spring metal layer. The leads are disposed on a dielectric layer including an unbacked dielectric layer portion having a surface positioned between the major surfaces of the spring metal layer.

Abstract: An integrated lead head suspension flexure including a spring metal base layer, an insulating layer on the base layer and traces on the insulating layer. The traces include first and second adjacent and co-planar write traces and first and second shield traces. The shielding traces are on opposite sides of the write traces, electrically interconnected and generally co-planar with the write traces. Portions of the stainless steel layer below the traces include windows. The shield traces can be connected to ground and/or to the spring metal base layer.

Abstract: A method for constructing a dual fluoroscopy system according to embodiments of the present invention includes providing a first c-arm and a second c-arm, each of which include an x-ray generator and an imaging device, synchronizing exposure timing of the two x-ray generators, decoupling the x-ray generators from the imaging devices and mounting them on a gantry system, aligning one x-ray generator with an imaging device and aligning the other x-ray generator with the other imaging device, and performing a calibration test to determine the dual fluoroscopy system configuration, and attaching a triggering and visualization device. An imaging system of the imaging device may be upgraded to permit faster data capture rates, according to embodiments of the present invention.