Abstract: Methods, systems and business models are provided for an effective personal advisor service. According to one embodiment, a personal advisor service performs a method of identifying and notifying a subscriber of the personal advice service of information regarding potential transactions, potential transaction providers, or transactable information determined to address or alleviate a need of the subscriber. First, a computer system of a personal advice service receives information indicative of one or more needs of the subscriber of the advice service. The personal advice service then generates information regarding one or more offers for the subscriber by identifying and selecting among potential transactions, potential transaction providers, or transactable information that are determined to address or alleviate a need of the one or more needs.

Abstract: A system includes multiple slave devices implanted in a human body, wherein each slave device includes a communication module operable to receive transmitted communications and is associated with a permanent device identifier. The system further includes a master device including a communications module operable to address a first communication to a selected slave device using the permanent device identifier associated with the selected slave device, wherein the first communication includes a local identifier assigned to the selected slave device, the assigned local identifier does not match any other local identifier assigned to any other slave device implanted in the human body, and subsequent communications are addressed to the selected slave device using the assigned local identifier.

Abstract: Devices and methods for treating a damaged intervertebral disc to reduce or eliminate associated back pain. The present invention provides disc reinforcement therapy (DRT) which involves implanting one or more reinforcement members in and preferably around the annulus of the disc. The reinforcement members may be used to stabilize the annulus and/or compresses a portion of the annulus so as to reduce a bulge and/or close a fissure. The implantable devices and associated delivery tools may incorporate heating capabilities to thermally treat the annular tissue. Alternatively or in combination, other devices may be specifically employed for such thermal treatment.

Abstract: A biomimetic electrode material including a fibrous matrix including a conductive polymer and an ion conducting polymeric material is described. The biomimetic electrode material may be used in a number of body-implantable application including cardiac and neuro-stimulation applications. The biomimetic electrode material can be formed using electrospinning and other related processes. The biomimetic electrode may facilitate efficient charge transport from ionically conductive tissue to the electronically conductive electrode and may induce surrounding tissue to attach or interface directly to the implanted device, increasing the biocompatibility of the device.

Abstract: Bituminous paving mixtures containing lubricating agents or additives may be prepared at hot mix temperatures and cooled, paved and compacted at temperatures 10-55 Celsius degrees lower than the hot mix temperatures. The increased temperature range between the hot mix temperatures and the paving and compacting temperatures is facilitated by the improved compacting properties of the paving mixture when it includes the lubricating agents or additives.

Abstract: Methods and devices for interconnecting a medical lead conductor member and an electrode are provided. One device includes a medical lead having a shaft. The shaft has a conductor member extending therethrough and a ring electrode disposed along the shaft. The ring electrode has a fixation device disposed within the ring electrode, and the fixation device forms an interference fit with the conductor member, forming an electrical contact therebetween. Also provided are methods for forming an electrical interconnect between a ring electrode and a conductor member.

Abstract: Apparatus and method for detecting connectivity in a channel in an endoscope undergoing reprocessing using an automatic reprocessor, the apparatus including a source of pressurized fluid which may be a gas alone or gas and liquid and a back pressure detector connected to the channel or channels of interest in the endoscope, the method including providing a source of pressurized fluid, directing the pressurized fluid to a channel in an endoscope, monitoring the time for the back pressure in the pressurized fluid to decay to a predetermined level; and determining whether the channel is connected and open or disconnected by comparing the decay time of the actual back pressure to one or more predetermined values corresponding to the specific channel or channels and model of endoscope undergoing reprocessing.

Abstract: An implantable lead assembly includes a lead body extending from a proximal end to a distal end having an intermediate portion therebetween, where the lead body includes an insulating layer. A conductor is disposed within the insulating layer and the insulating layer surrounds the conductor. An electrode is coupled to the lead body, and the electrode is in electrical communication with the conductor. At least one conductive sleeve is disposed within the insulating layer. The at least one conductive sleeve surrounds the conductor and is electrically isolated from the electrode. The at least one conductive sleeve has a first impedance value in a first condition.

Abstract: An apparatus and method for making a compliant interconnect assembly adapted to electrically couple a first circuit member to a second circuit member. The first dielectric layer has a first major surface and a plurality of through openings. A plurality of electrical traces are positioned against the first major surface of the first dielectric layer. The electric traces include a plurality of conductive compliant members having first distal ends aligned with a plurality of the openings in the first dielectric layer. The first distal ends are adapted to electrically couple with the first circuit member. The second dielectric layer has a first major surface positioned against the electric traces and the first major surface of the first dielectric layer. The second dielectric layer has a plurality of through openings through which the electric traces electrically couple with the second circuit member.

Abstract: A medical electrical lead and body implantable electrode suitable for a variety of medical applications are disclosed. In general, the electrode includes a composite material having particles of pseudo-capacitive material, such as iridium oxide, dispersed within a polymer matrix including a polyelectrolyte. The polymer matrix can also include a conductive polymer doped with an excess of the polyelectrolyte. The composite may used to form the electrode itself or an electrode coating. The presence of a pseudo-capacitive material within the composite may increase the charge-storage capacity of the electrode and may allow for safe deliveries of charge densities within an electrochemical window suitable for pacing a patient's heart.

Abstract: Layered interface materials described herein include at least one pulse-plated thermally conductive material, such as an interconnect material, and at least one heat spreader component coupled to the at least one pulse-plated thermally conductive material. A plated layered interface material having a migration component is also described herein and includes at least one pulse-plated thermally conductive material; and at least one heat spreader component, wherein the migration component of the plated layered interface material is reduced by at least 51% as compared to the migration component of a reference layered interface material. Another layered interface material described herein includes: a) a thermal conductor; b) a protective layer; c) a layer of material to accept solder and prevent the formation of oxides; and d) a layer of solder material.

Abstract: The present invention concerns methods, compositions and apparatus for neutralizing bioagents, wherein bioagents comprise biowarfare agents, biohazardous agents, biological agents and/or infectious agents. The methods comprise exposing the bioagent to an organic semiconductor and exposing the bioagent and organic semiconductor to a source of energy. Although any source of energy is contemplated, in some embodiments the energy comprises visible light, ultraviolet, infrared, radiofrequency, microwave, laser radiation, pulsed corona discharge or electron beam radiation. Exemplary organic semiconductors include DAT and DALM. In certain embodiments, the organic semiconductor may be attached to one or more binding moieties, such as an antibody, antibody fragment, or nucleic acid ligand. Preferably, the binding moiety has a binding affinity for one or more bioagents to be neutralized. Other embodiments concern an apparatus comprising an organic semiconductor and an energy source.

Abstract: A method for stringing a first elongate element through a second elongate element is provided by placing the first elongate element in a channel and injecting compressed gas into the channel to propel the first elongate element therethrough. The channel has a first open end, and the second elongate element is sealed around the first open end. Compressed gas is injected into the channel towards the second elongate element, propelling the first elongate element through the second elongate element. Also disclosed is a system for performing such a method, including a source of compressed gas and a housing having a channel with a first end and a second open end. The first end is in fluid communication with the source of compressed gas. The channel has a tapered portion adjacent the open end of the channel, and the channel defines a straight longitudinal axis between the first end and the second open end.

Abstract: Electrodes for tissue stimulation and sensing can comprise a support with nanostructures disposed on the support. Pairs of the electrodes can be placed in close proximity to one another. When electrical energy is supplied to the electrodes, an electrical field (and possibly an electrical current) can be established between the nanostructures on the electrodes. The nanostructures may have cells disposed thereon, for example myocardial cells, myocardial progenitor cells, neural cells and/or stem cells. In addition, the electrodes can be arranged in arrays.

Abstract: A computer-based method that allows automated measurement of a number of metrics that likely reflect the quality of a colonoscopic procedure. The method is based on analysis of a digitized video file created during colonoscopy, and produces information regarding insertion time, withdrawal time, images at the time of maximal intubation, the time and ratio of clear versus blurred or non-informative images, and a first estimate of effort performed by the endoscopist. As these metrics can be obtained automatically, the method allows future quality control in the day-to-day medical practice setting on a large scale. In addition, the method can be adapted to other healthcare procedures. The method may be useful to assess progress during colonoscopy training, or as part of endoscopic skills assessment evaluations.

Abstract: Apparatus and method for quickly disconnecting a wetted parts subassembly from a paint spray gun wherein the wetted parts subassembly includes a spray tip, pump cylinder and piston and paint cup components including a pump housing cylinder support carrying the pump cylinder and having a pair of protrusions formed on a pump housing cylinder support, a frame having a pair of slots aligned to receive the protrusions when the pump housing cylinder support is received in the frame, a locking lever pivotably attached to the frame adjacent at least one of the slots and movable between a latched position wherein the pump housing cylinder support is retained to the frame, and an unlatched position wherein the pump housing cylinder support is removable from the frame. A passive retention feature frictionally engages the wetted parts subassembly with the frame when the wetted parts subassembly is received in the frame.