Abstract: A microwave broadside coupled balun integral in a multi-layer printed wiring board formed by broadside coupled conductors embedded in the multi-layer printed wiring board. The balun may be used to form components which are integrated into the multi-layer printed wiring board, such as a microwave mixer formed by two of said broadside coupled baluns embedded in a multi-layer printed wiring board and connected to a diode ring quad.

Abstract: The present invention concerns novel methods for enhancing the mechanical performance of tissue adhesives and sealants which comprises employing a primer molecule in association with a tissue adhesive or sealant, wherein the primer molecule serves to enhance the strength of the interface between the tissue and the adhesive matrix. The primer molecules described herein function to interact with a protein present in the tissue, thereby altering its characteristics to make it more amenable to bonding with the adhesive matrix. Primer molecules may be applied to the tissue independently from the tissue adhesive or sealant or may be mixed with the tissue adhesive or sealant prior to application to the tissue.

Abstract: A transfer valve assembly (10) for use as a feed valve or a discharge valve includes a series of open-faced pockets (46) biased by leaf springs (48) off of a central hub (44) and an arcuate saddle piece (22) mounted at an opening (14) of a sterilizer vessel (12) for transferring containers from an infeed conveyor (34) onto an interior reel (18). The engagement of open-faced pockets (46) with saddle (22) creates a seal to prevent the escape of steam, but gaps are provided between pockets (46) which allow for a controlled escape of steam in a manner that allows the pressure within the sterilizer vessel to be maintained at a slightly elevated level.

Abstract: A canopy top for use with a vehicle having an open passenger compartment and carrying equipment. The canopy top has a frame adaptable for being secured to the vehicle and supported above the passenger compartment. A canopy overlies the frame. Means formed integral with the frame for securing equipment to the top is provided.

Abstract: The present invention provides for the selective covalent modification of nucleic acids with redox active moieties such as transition metal complexes. Electron donor and electron acceptor moieties are covalently bound to the ribose-phosphate backbone of a nucleic acid at predetermined positions. The resulting complexes represent a series of new derivatives that are bimolecular templates capable of transferring electrons over very large distances at extremely fast rates. These complexes possess unique structural features which enable the use of an entirely new class of bioconductors and photoactive probes.

Abstract: A novel structure and method are taught for fully discharging a capacitor and thereby reducing the capacitance needed to achieve a desired RC time constant. The invention overcomes the previously encountered problem of using a large and area-inefficient capacitor. The invention allows for conservation of integrated circuit space and is cost effective.

Abstract: There is disclosed an apparatus (1) for use in a suction blister technique of sampling fluid from the human or animal body. The apparatus (1) comprises a cup (2) defining a chamber and having a rim portion (3) defining an aperture (5) communicating with the chamber. An annular flange (6) extends outwardly from the rim portion (3) whereby in use the flange (6) is sealingly attached to the body such that an area of skin closes the aperture (5). A ducted portion (11) is connected to the cup (2) and defines duct (12) which communicates with the chamber. The cup (2) further comprises a roof (4) which merges with the rim portion (3) and is formed of a resiliently deformable material having a shape memory which urges the roof (4) into an expanded configuration in which the roof (4) is held clear of the aperture (5). The roof is however deformable to a collapsed configuration in which it is proximal to the aperture (5).

Abstract: Improved oral cyclosporin formulations which have high bioavailability and are capable of admiration in hard capsules are provided. In the subject formations, cyclosporin is delivered in an orally acceptable vehicle comprising at least one alkanol solvent of from 2 to 3 carbon atoms in combination with at least one non-ionic surfactant. The subject formalations may further comprise at least one cosolvent, where cosolvents of interest include fatty acids and diols. The subject formulations find use in immuno-suppressive therapy.

Abstract: Air conditioning system and method in which a refrigerant from a compressor is circulated through a cooling element within a hermetically sealed, thermally insulated cooling compartment to cool a fluid within the compartment, and transferring the cooled fluid out of the compartment for use in cooling a space. In one disclosed embodiment, the fluid which is cooled is air which is blown out of the compartment into the space to be cooled. In another disclosed embodiment, the fluid is a coolant which is contained within a vertically extending tube that extends both within the compartment and through a heat exchanger positioned beneath the compartment, with air being cooled by blowing it through the heat exchanger and then into the space to be cooled.

Abstract: The invention relates to methods for targeting an exogenous polynucleotide or exogenous complementary polynucleotide pair to a predetermined endogenous DNA target sequence in a eukaryotic cell by homologous pairing, particularly for altering an endogenous DNA sequence, such as a chromosomal DNA sequence, typically by targeted homologous recombination. In certain embodiments, the invention relates to methods for targeting an exogenous polynucleotide having a linked chemical substituent to a predetermined endogenous DNA sequence in a metabolically active eukaryotic cell, generating a DNA sequence-specific targeting of one or more chemical substituents in an intact nucleus of a metabolically active eukaryotic cell, generally for purposes of altering a predetermined endogenous DNA sequence in the cell.

Abstract: The invention provides novel DNA polymerases of the &bgr;-family, called &bgr;-type DNA polymerases. Nucleic acids encoding &bgr;-type DNA polymerases are provided, as well as expression vectors and host cells containing the nucleic acid encoding the &bgr;-type DNA polymerases. The invention further relates to methods for synthesizing nucleic acid using &bgr;-type DNA polymerases.

Abstract: The invention provides antibodies directed against a G protein-activated, inward rectifying KGA potassium channel polypeptide.

Abstract: There is provided a monitor and method for monitoring the condition of a photoresist film on a wafer in which the phase of high frequency ultrasonic pulses reflected from the wafer/photoresist interface provides an indication of the condition of the photoresist film.

Abstract: A method for forming a valve-like mechanism in a body of a mammal having an esophagus extending through a lower esophageal sphincter to a stomach and formed by a wall having a muscle layer and a mucosal layer. The method comprises the step of forming at least one implant in the muscle layer of the wall in the vicinity of the lower esophageal sphincter. The at least one implant inhibits opening of esophagus at the lower esophageal sphincter and causes the mucosal layer to appose in the vicinity of the implants.

Abstract: A method for treating a gastrointestinal tract in a body of a mammal. At least one nonaqueous solution is introduced into the wall. A nonbiodegradable solid is formed in the wall from the at least one nonaqueous solution to treat the wall. A kit for use in the procedure is provided.

Abstract: Chromatographic material having the general formula S-B-X-Y-L where S is a solid support, B is a binding group, X is a substantially non-ionic hydrophilic organic spacer, Y is a coupling group and L is an affinity ligand. The chromatographic material is substantially free of non-specific adsorption and is stable at high pH.

Abstract: The fault system includes an interface for accessing first data fault representative of faults in the reported by users of mobile stations of the network, an interface for accessing second fault, data representative of faults in the network determined by a network analysis system, and pattern matching device for allocating the first and second fault data to fault patterns, representative of faults having at least one common characteristic. The common characteristics is geographic location and fault type. The fault system further includes pattern generation device for generating the fault pattern using respective fault templates to allocate the fault data to the fault patterns.

Abstract: A system and method for efficient coupling between optical elements comprises a memory containing an alignment module configured to align a light beam with an optical element to maximize coupling efficiency, and a processor coupled to the memory to control the alignment module. A position sensitive device indirectly senses a position of the light beam on the optical element and sends the position to the processor. The alignment module directly measures coupling efficiency where the light beam contacts the optical element. The alignment module identifies a direction of increasing coupling efficiency and aligns the light beam with the optical element along that direction until maximum coupling efficiency is achieved.

Abstract: Ultrasound apparatus for examining tissue in a region of interest in a body comprising a housing having a viewing aperture. An ultrasonic transducer is provided comprised of an array of ultrasonic elements disposed in the viewing aperture. Electrical pulses are supplied to the transducer for transducer excitation to introduce ultrasonic signals into the body for reflection from the tissue in the region of interest. The transducer is capable of converting ultrasonic signals reflected from the tissue within the body to the transducer to provide electrical signals. The electrical signals are gain corrected in accordance with time. In-phase and out-of-phase components of the electrical signals are provided and then digitized. The digitized electrical signals are collected to form one image for a single frame of the tissue in the region of interest in the body from transducer excitations less than thirty-three in number which is then displayed.

Abstract: A GPS system and method for generating precise position determinations. The GPS system includes a ground based GPS reference system which receives with a reference receiver GPS signals and makes phase measurements for the carrier components of the GPS signals. The GPS reference system then generates and broadcasts an initialization signal having a carrier component and a data link signal having a data component. The data component of the data link signal contains data representing the phase measurements made by the reference receiver. The GPS system also includes a GPS mobile system which receives with a mobile position receiver the same GPS signals as were received by the reference system. In addition, the GPS position receiver receives the data link and initialization signals broadcast by the reference system.