Patents Represented by Attorney, Agent or Law Firm Foley, Hoag & Eliot LLP
  • Patent number: 6393043
    Abstract: In a tiltable arc furnace in which a furnace vessel (2) and a portal (4) for an electrode lifting and pivoting apparatus are arranged on a platform (1 and 3) of a furnace cradle which is tiltable by a tilting apparatus and which includes two mutually spaced cradle runner skids (16) which each run on a respective support path (17), wherein the furnace vessel (2) is arranged on a first platform region which is between the cradle runner skids (16) and the portal (4) is arranged on a second platform region which is outside the cradle runner skids (16) the two platform regions are in the form of separate platform portions (1, 3) which are connected together by a hinge pivot (13), the portal platform portion (3) carrying the portal (4) is supported by way of a further cradle runner skid (20) on a further rolling path (21) and is tiltable by the tilting apparatus synchronously with the vessel platform portion (1) carrying the furnace vessel (2).
    Type: Grant
    Filed: February 8, 2001
    Date of Patent: May 21, 2002
    Assignee: Arcmet Technologie GmbH
    Inventor: Gerhard Fuchs
  • Patent number: 6386046
    Abstract: A method for determining the pulsatile flow characteristics in fluid flow driven by a periodic pressure disturbance includes the step of evaluating the spectrum of a signal representative of the vortices generated by a vortex flowmeter. Because of the periodic pressure disturbance, the signal is an FM signal in which a carrier, having a frequency corresponding to the vortex-shedding frequency in the absence of pulsating flow, is modulated by the periodic pressure disturbance. The pulsation frequency and amplitude are then estimated on the basis of the separation between adjacent sidebands of the spectrum of the FM signal and the relative amplitudes of the sidebands.
    Type: Grant
    Filed: September 28, 1999
    Date of Patent: May 14, 2002
    Assignee: The Foxboro Company
    Inventor: Wade Mattar
  • Patent number: 6388052
    Abstract: The invention provides novel polypeptides which are associated with the transcription complex NF-AT, polynucleotides encoding such polypeptides, antibodies which are reactive with such polypeptides, polynucleotide hybridization probes and PCR amplification probes for detecting polynucleotides which encode such polypeptides, transgenes which encode such polypeptides, homologous targeting constructs that encode such polypeptides and/or homologously integrate in or near endogenous genes encoding such polypeptides, nonhuman transgenic animals which comprise functionally disrupted endogenous genes that normally encode such polypeptides, and transgenic nonhuman animals which comprise transgenes encoding such polypeptides.
    Type: Grant
    Filed: March 9, 1998
    Date of Patent: May 14, 2002
    Assignee: Board of Trustees of the Leland Stanford Junior University
    Inventors: Gerald R. Crabtree, Jeffrey P. Northrop, Steffan N. Ho
  • Patent number: 6383775
    Abstract: The invention provides a method for engineering and selecting an active protease able to cleave a user-defined target amino acid sequence. The method is useful for designing proteases for medical therapeutics and industrial applications.
    Type: Grant
    Filed: March 11, 1999
    Date of Patent: May 7, 2002
    Assignee: Interleukin Genetics, Inc.
    Inventors: Gordon W. Duff, Jon R. Sayers, Srdjan Vitovski
  • Patent number: 6380815
    Abstract: The invention relates to a microwave pulse generator for generating microwave pulses with a pulse duration in the nanosecond range. The microwave pulse generator includes a pulse generator for generating control pulses of a constant pulse duration and a microwave oscillator generating microwave oscillations. The microwave oscillator includes a transistor amplifier, to which a frequency-determining resonant circuit and an ohmic device for reducing the resonant Q-value are connected in such a way that a control pulse of the pulse generator applied to an input terminal of the transistor amplifier causes the microwave oscillator to produce a microwave oscillation that can be tapped at an output terminal of the microwave oscillator, wherein the microwave oscillation follows at least approximately the temporal course of the control pulse.
    Type: Grant
    Filed: November 2, 2000
    Date of Patent: April 30, 2002
    Assignee: Vega Grieshaber KG
    Inventors: Josef Fehrenbach, Gregor Storz, Daniel Schultheiss
  • Patent number: 6376549
    Abstract: Compositions and methods using same for the treatment of diabetes its sequelae and pre-diabetic conditions are provided. Invention compositions include the anti-diabetic agent metformin, and bioavailable sources of one or more of chromium, vanadium and magnesium. Also provided are pharmaceutical agents containing invention compositions and methods for administering such agents.
    Type: Grant
    Filed: September 17, 1998
    Date of Patent: April 23, 2002
    Assignee: Akesis Pharmaceuticals, Inc.
    Inventors: Stuart A. Fine, Kevin J. Kinsella
  • Patent number: 6376644
    Abstract: Biodegradable polymers are described comprising the recurring monomeric units shown in formula I or II: wherein X is —O— or —NR′—, where R′ is H or alkyl; L is a branched or straight chain aliphatic group having from 1-20 carbon atoms; M1 and M2 are each independently (1) a branched or straight chain aliphatic group having from 1-20 carbon atoms; or (2) a branched or straight chain, oxy-, carboxy- or amino-aliphatic group having from 1-20 carbon atoms; Y is —O—, —S— or —NR′—, where R′ is H or alkyl; R is H, alkyl, alkoxy, aryl, aryloxy, heterocyclic or heterocycloxy; the molar ratio of x:y is about 1; the molar ratio n:(x or y) is between about 200:1 and 1:200; and the molar ratio q:r is between about 1:99 and 99:1; wherein said biodegradable polymer is biocompatible before and upon biodegradat.
    Type: Grant
    Filed: September 1, 2000
    Date of Patent: April 23, 2002
    Assignees: Guilford Pharmaceuticals, Inc., Johns Hopkins University School of Medicine
    Inventors: Hai-Quan Mao, Kam W. Leong, Zhong Zhao, James P. English
  • Patent number: 6376670
    Abstract: The present invention provides methods and pharmaceutical preparations that inhibit the growth of bacterial microorganisms, via a non-lytic mechanism. Additionally, the present invention provides methods and pharmaceutical preparations that kill bacterial microorganisms, via a non-lytic mechanism.
    Type: Grant
    Filed: September 8, 2000
    Date of Patent: April 23, 2002
    Assignee: Sepracor Inc.
    Inventors: Gregory D. Cuny, James R. Hauske, Michael Z. Hoemann, Ian Chopra
  • Patent number: 6377054
    Abstract: A test device is described for testing an electromagnetic quantity, such as a voltage or a magnetic field. The test device includes a housing, a sensor arranged in the housing and sensing the electromagnetic quantity, a processing circuit for processing to signals received from the sensor, display elements for displaying the signals processed by the processing unit, a galvanic element for supplying power to the test device, an illuminator for illuminating an area to be tested, and a switch for activating the illuminator. The test device has a small footprint and does not require an external light source even under difficult lighting conditions.
    Type: Grant
    Filed: July 20, 1999
    Date of Patent: April 23, 2002
    Assignee: Ch. Beha GmbH
    Inventor: Christian Beha
  • Patent number: 6376532
    Abstract: The present invention provides bicyclic metabotropic glutamate receptor ligands, as well as compositions comprising such ligands, and and methods for their use.
    Type: Grant
    Filed: January 25, 2001
    Date of Patent: April 23, 2002
    Assignee: Georgetown University
    Inventors: Alan P. Kozikowski, Darryl Hugh Steensma, Werner Tueckmantel, Gian Luca Araldi
  • Patent number: 6369943
    Abstract: A projection screen, having a projection surface formed of at least two segments, of which at least two segments are sound radiating segments capable of radiating sound waves from the projection surface and designed to reproduce different frequency ranges.
    Type: Grant
    Filed: December 22, 2000
    Date of Patent: April 9, 2002
    Assignee: Harman Audio Electronic Systems GmbH
    Inventors: Wolfgang Bachmann, Gerhard Krump, Hans-Jürgen Regl
  • Patent number: 6370335
    Abstract: A flash unit comprising a flash light source (2) and a projector lens (8) positioned to project light from the flash source onto a subject. In a preferred embodiment there are two flash light sources for projecting patterned and unpatterned light respectively on to the subject, and a circuit is provided to trigger the two flash sources with a predetermined time interval therebetween.
    Type: Grant
    Filed: December 20, 1999
    Date of Patent: April 9, 2002
    Assignee: C3D Limited
    Inventors: Timothy Bryan Niblett, Paul William Cockshott
  • Patent number: 6370525
    Abstract: A method for processing a search query uses the results of a search performed on a high quality, controlled database to assess the relevance of documents retrieved from a search of an uncontrolled public database having documents of highly variable quality. The method includes the steps of parsing the search query and then searching the authoritative database to generate authoritative database results. The search query is also used to search the public database, thereby generating public database results. The quality or relevance of the public database results are then quantified on the basis of the authoritative database results, thereby generating a quality index. The results from both the authoritative and the public databases are then ranked on the basis of this quality index.
    Type: Grant
    Filed: November 13, 2000
    Date of Patent: April 9, 2002
    Assignee: KCSL, Inc.
    Inventor: Ilia Kaufman
  • Patent number: 6369237
    Abstract: The present invention pertains to novel inhibitors of DNA glycosylases. The invention is based at least in part on the observation that specific substituted pyrrolidines, and analogs thereof, are capable of specifically inhibiting DNA glycosylases, e.g., as transition state analogs, and consequently are useful for modulation of DNA repair. Such compounds can, for example, be used for treating subjects having a disorder associated with excessive cell proliferation, such as in the treatment of various cancers. Furthermore, these glycosylase inhibitors can be used as anti-bacterial, anti-viral and anti-fungal agents.
    Type: Grant
    Filed: March 7, 1997
    Date of Patent: April 9, 2002
    Assignee: President and Fellows of Harvard College
    Inventors: Gregory L. Verdine, Li Deng
  • Patent number: 6369223
    Abstract: The present invention relates to a process for stereoselective cycloaddition reactions which generally comprises a cycloaddition reaction between a pair of substrates, each either chiral or prochiral, that contain reactive &pgr;-systems, in the presence of a non-racemic chiral catalyst, to produce a stereoisomerically enriched product. The present invention also relates to novel asymmetric catalyst complexes comprising a metal and an asymmetric tridentate ligand.
    Type: Grant
    Filed: January 4, 2001
    Date of Patent: April 9, 2002
    Assignee: President and Fellows of Harvard College
    Inventors: Eric N. Jacobsen, Scott E. Schaus, Alexander G. Dossetter, Timothy F. Jamison
  • Patent number: 6370289
    Abstract: The invention is directed to an apparatus and a method for reducing noise, in particular RIN noise, in optical sensors, in particular fiber-optic sensors. The optical sensor produces a sensor output signal representing a physical quantity to be measured and also contains a first noise component, which is detected by a first detector. A separate detector detects an input light noise component of the input light source of the optical sensor and produces a second noise component. The second noise component is electronically processed and time-delayed or phase shifted by a time delay which substantially correspond to the time delay experienced by the sensor input light traversing the optical sensor. The time-delayed processed signal is then subtracted from the sensor output signal to produce a reduced noise optical sensor signal corresponding to the measured physical quantity.
    Type: Grant
    Filed: January 12, 2000
    Date of Patent: April 9, 2002
    Assignee: KVH Industries, Inc.
    Inventor: Sidney M. Bennett
  • Patent number: 6365881
    Abstract: A self-protecting heating system comprises an electrically conductive medium, an alternating current source and at least two electrodes. The alternating current source is in contact with at least one electrode at each pole, and the electrodes are in electrical contact with the electrically conductive medium. The electrodes are made of passive metals or passive alloys. The electrically conductive medium may be an aqueous solution or water. The system is preferably provided with a thermostat that disconnects the electrical power from the electrodes once a desired temperature has been reached.
    Type: Grant
    Filed: April 12, 1999
    Date of Patent: April 2, 2002
    Inventor: David Itzhak
  • Patent number: 6361299
    Abstract: A spoolable composite member having a sensor and an energy conductor embedded in the composite member. The spoolable composite member is capable of being spooled onto a reel for storage and for use in oil field applications. The spoolable tube exhibits unique anistropic characteristics that provide improved burst and collapse pressures, increased tensile strength, compression strength, and load carrying capacity, while still remaining sufficiently bendable to be spooled onto a reel in an open bore configuration. The spoolable composite tube can include an inner protective layer, an inner pressure barrier layer, an interface layer, fiber composite layers, an outer pressure barrier layer, and an outer protective layer.
    Type: Grant
    Filed: November 2, 1999
    Date of Patent: March 26, 2002
    Assignee: Fiberspar Corporation
    Inventors: Peter A. Quigley, Stephen C. Nolet
  • Patent number: D457667
    Type: Grant
    Filed: March 21, 2001
    Date of Patent: May 21, 2002
    Assignee: Color Kinetics, Inc.
    Inventors: Colin Piepgras, Ralph Osterhout
  • Patent number: D457669
    Type: Grant
    Filed: August 1, 2001
    Date of Patent: May 21, 2002
    Assignee: Color Kinetics, Inc.
    Inventors: Colin Piepgras, Ralph Osterhout