Abstract: The present invention is directed to compounds of formula (I) and pharmaceutically acceptable salts, esters, and prodrugs thereof which are inhibitors of Factor Xa. The present invention is also directed to intermediates used in making such compounds, pharmaceutical compositions containing such a compound, methods to prevent or treat a number of conditions characterized by undesired thrombosis and methods of inhibiting the coagulation of a blood sample.

Abstract: A method of creating a backup copy of a plurality of files is provided. A block of memory having a predetermined memory size is allocated at a first device. A first header including an identifier of a file of the plurality of files received from a second device is defined. The first header is written to the allocated block of memory. A second header including the identifier of the file is defined. The second header and the file are written to the allocated block of memory. The process of defining the second header and writing the second header and the file to the allocated block of memory is repeated for each file of the plurality of files. The allocated block of memory is copied to a third device after processing each of the plurality of files.

Abstract: A method for using a network appliance to efficiently buffer and encrypt data for transmission includes: receiving, by an appliance via a connection, two or more SSL records comprising encrypted messages; decrypting the two or more messages; buffering, by the appliance, the two ore more decrypted messages; determining, by the appliance, that a transmittal condition has been satisfied; encrypting, by the appliance in response to the determination, the first decrypted message and a portion of the second decrypted message to produce a third SSL record; and transmitting, by the appliance via a second connection, the third record. Corresponding systems are also described.

Abstract: The present application is directed towards systems and methods of state migration in a multi-core system. An external process on a client or server may initiate a plurality of connections with the multi-core system, such that some cores have a plurality of connections and others have none. The present invention provides systems and methods for redirecting a connection or migrating the state of a connection from being associated with a first core with a plurality of connections to a second core with no connections.

Abstract: A system for facilitating virtualization of a heterogeneous processor pool includes a processor allocation component and a hypervisor, each executing on a host computer. The processor allocation component identifies a plurality of physical processors available for computing and determines a set of flags, each of the set of flags identifying a type of functionality provided by each of a subset of the plurality of physical processors. The hypervisor, in communication with the processor allocation component, allocates, to at least one virtual machine, access to one of the subset of the plurality of physical processors.

Abstract: The present invention relates to spectacles comprising a spectacle frame and a spectacle glass. The spectacle frame, in turn, comprises a frame which defines a receiving opening for the spectacle glass and essentially completely borders the spectacle glass. The spectacle glass is fixed in the receiving opening by means of a thread inserted between the frame defining the receiving opening and the edge of the spectacle glass.

Abstract: Methods and systems for improving resource utilization when remoting three dimensional graphics commands that are generated by an application executing on a local computing machine. An agent that executes on a local computing machine intercepts a first call to a drawing library. The application generates this first call to request information from the drawing library. The agent further transmits a first frame that is generated by the application, to a remote computing machine, and prevents a return of the first call to the requesting application until the agent receives a notification indicating either the first frame was transmitted to the remote computing device or the first frame was rendered. Upon receiving such a notification, the agent permits the return of the first call to the requesting application.

Abstract: A wiring board of the present invention comprises a plurality of device formation areas each for mounting a semiconductor chip thereon, and two or more slits formed in an area which comes into contact with a molding die when the wiring board is placed in a cavity of the molding die for forming a sealant to collectively cover the plurality of device formation areas.

Abstract: A method and system for assigning access control levels when granting access to resources includes a client node, a collection agent, and a policy engine. The client node requests access to a resource. The collection agent gathers information about the client node. The policy engine receives the gathered information and assigns one of a plurality of levels of access responsive to application of a policy to the received information and transmits the information.

Abstract: A semiconductor device includes a semiconductor chip, and an encapsulation resin which covers and encapsulates the semiconductor chip, the semiconductor chip having a recess formed in the surficial portion thereof; the recess having, on the deeper side than a predetermined portion thereof, a portion having a larger width than the predetermined portion has; and the encapsulation resin being anchored in the recess.

Abstract: The invention relates to a medicament which comprises a peptide extract of avocado and which can also comprise a composition containing D-mannoheptulose and/or perseitol, such as a water-soluble extract of avocado sugars, and/or a peptide extract of lupine. The inventive medicament is intended for the treatment and/or prevention of illnesses that are linked to an alteration in innate and/or acquired immunity, through an increase in the production of anti-microbial peptides, preferably hBD-2, without inducing inflammatory reactions, irritations or intolerances.

Abstract: Described herein are semiconductor device packages with EMI shielding and related methods. In one embodiment, a semiconductor device package includes: (1) a substrate unit including a grounding element disposed adjacent to a periphery of the substrate unit; (2) a semiconductor device disposed adjacent to an upper surface of the substrate unit; (3) a package body disposed adjacent to the upper surface and covering the semiconductor device; and (4) an EMI shield disposed adjacent to exterior surfaces of the package body and electrically connected to a connection surface of the grounding element. A lateral surface of the package body is substantially aligned with a lateral surface of the substrate unit, and the connection surface of the grounding element is electrically exposed adjacent to the lateral surface of the substrate unit. The grounding element corresponds to a remnant of a grounding via, and provides an electrical pathway to ground electromagnetic emissions incident upon the EMI shield.

Abstract: A packet communication device autonomously selects an appropriate operation mode according to a connection environment to an external device before a service of the device is started. When the device is connected to the external buses, connection interface units notify an external device discrimination unit of connection of the device. The external device discrimination unit issues a polling packet to the connected device, discriminates the connected external device on the basis of the response packet, and notifies an operation mode switching unit. The operation mode switching unit selects an operation mode conforming to a connection environment of the packet communication device to the external device and switches the operation mode of the device to the mode.

Abstract: A dynamic spine plate is formed with only a single row of bone screw bores that extend along a generally superior/inferior axis of the spine plate, providing a single-sided dynamic spine plate. The single-sided dynamic spine plate is formed from a plurality of spine plate components that are coupled dynamically to one another. This provides a modular, single-sided dynamic spine plate. The spine plate components are coupled dynamically to one another via socket and projection interfaces, the socket and projections interfaces incorporating resilient coupling and retention structures that allow limited movement of the spine plate components relative to one another. This provides for dynamic extension of the spine plate components relative to one another. The resilient coupling structure connects the spine plate components, providing a self-biased, snap fit coupling of spine plate components.

Abstract: A paper sheet counting apparatus includes a hopper; a transport mechanism that feeds the paper sheets to a transport path one by one, and transports the paper sheets along the transport path; a sensing unit including a counting sensor for counting the paper sheets; and a stacker. The transport mechanism includes a drive roller constituting an inside of a turn portion for changing a direction of the transport path; pinch rollers that biases the paper sheet against the drive roller; and a turn guide plate arranged between the pinch rollers to guide the paper sheet along an outer periphery of the drive roller. The turn guide plate is formed such that a front edge of the paper sheet transported to the turn portion is guided to a contact portion between a pinch roller arranged on a downstream side and the drive roller.

Abstract: The invention inter alia relates to a method of fabricating a layer assembly comprising the steps of: arranging a first layer on top of a carrier; arranging a second layer on top of the first layer; locally modifying the material of the buried first layer and providing at least one modified section in the first layer, wherein the modified material changes or induces mechanical strain in a portion of the second layer which is arranged above the at least one modified section; after locally modifying the material of the buried first layer, depositing a third material on top of the second layer, at least one characteristic of the third material being sensitive to the local mechanical strain in the second layer.

Abstract: This invention enables information on a connection wiring with a substrate of a mounted component to be accurately and easily inputted in an X-ray examination apparatus. In teaching of a substrate examination, when a user inputs a two-dimensional region of a component to be examined with respect to a visible light image of the substrate, three-dimensional data is generated for the relevant region, which data is then analyzed to acquire a center coordinate, the number, the number of rows, and the number of columns on a ball terminal connecting the component to the substrate. Results such as the center coordinate acquired in such a manner may be displayed. The visible light image for the substrate is displayed in a display field of a screen.

Abstract: The object of the present invention is to provide a mouse model for allergic diseases such as atopic dermatitis, and a dermatitis mouse model with impaired skin-barrier function. The present inventors found out that a mouse that has been caused to completely lose the function of expressing profilaggrin protein and filaggrin protein by entirely or partially disrupting the endogenous gene encoding filaggrin by a genetic mutation such as deletion or replacement, can be used as a mouse model for allergic diseases or atopic dermatitis wherein the skin-barrier function has been impaired.