Abstract: A new and useful process is disclosed for manufacturing a device for use in a bioprocess, comprising: (a) providing solid support means insoluble in water or organic solvent solutions; (b) coating said solid support means with organic-solvent based polymeric film means capable of applying one or more biomaterials; and (c) adsorbing or covalently bonding at least one functional biomaterial to said polymeric film means. The polymeric film means, for example, can be used to coat antigens, antibodies, haptens, enzymes, living bacteria, yeasts, etc. (i.e., biomaterials) to a glass (or other) support material, e.g., a glass tube, with surprising retention of the biomaterial's essential characteristic properties. The solid support means include but are not limited to those comprising glass, ceramics, metals, polymers and woods. The device of the invention is particularly useful in various immunoassays using a solid support for separation of phases.

Abstract: Segmented copolyesters/copolyethers in which the soft segment polyethers incorporate a thermally stable heterocyclic unit, e.g., hydantoin, are found to be useful as biomedical materials since the heterocyclic ring prevents crystallization of the soft segment, and further provides a chemically reactive site for incorporating other moieties to enhance certain properties, e.g., heparin for increasing the non-thrombogenicity of the biocompatible material.

Abstract: An effect yarn and process for manufacture thereof is disclosed when the effect comprises a slub that is formed after the yarn leaves the yarn package during later knitting or weaving operations. The effect yarn is particularly useful since it processes through such operations similar to conventional air-plied yarns.

Abstract: This disclosure relates to a process for preparing long-chain hydrocarbon substituted ureas by reacting a long chain fatty acid N-chloramide in isopropanol and/or tertiary butanol with an aliphatic or araliphatic primary or secondary amine in the presence of an alkali or alkaline earth hydroxide at a temperature of from 20.degree. to 100.degree. C. The process of this disclosure is particularly useful in preparing long-chain hydrocarbon substituted ureas wherein one of the aliphatic hydrocarbon substituents contains one or more hydroxyl and/or carboxyl groups, as well as the salts of such substituted ureas.

Abstract: A new and useful all plastic disposable thermometer is disclosed, which dispenses with the prior art employment of an aluminum or other metal-based substrate. The novel thermometer can either be employed with opaque indicator means or with heat-sensitive compositions of matter that change color with a change in phase, such as those enumerated in copending application Ser. No. 946,935, filed Sept. 28, 1978, now U.S. Pat. No. 4,232,552.

Abstract: A method for the demonstration and determination of an antigen or antibody in a test fluid, and to a test kit for the application of this method. The determination of the antigen or antibody is performed by utilizing two antibodies raised against the same antigen, but in different animal species. One of the antibodies is labeled. In order to separate the labeled-bound fraction from the labeled-free fraction, an insolubilized antibody directed against the unlabeled antibody is employed. For antigen determination, the unlabeled antibody is the antibody produced from the second animal species; for antibody determination, the unlabeled antibody can be either the antibody to be detected or determined or the antibody produced from the second animal species.

Abstract: Staple fibers made from crimped, in particular compression crimped, multicomponent filaments of the matrix/segment type, the cross section of which shows, in addition to the matrix, at least 6 peripheral wedge-shaped or lenticular segments, not completely covered by the matrix, are processed into a web, which is then mechanically bonded, preferably by needling. Subsequently, the fabric is subjected to a shrinkage process, by which its density is increased by more than 30%, the multicomponent fibers being completely or partly split up into their components. The difference in shrinkage between the components should be at least 10%. The liquids used for the shrinkage treatment are in particular organic liquids, such as methylene chloride, as well as other liquids producing a difference in shrinkage of at least 20%.

Abstract: Bis-N-chloramides of saturated aliphatic dicarboxylic acids are prepared by chlorinating a saturated aliphatic dicarboxylic diamide, the aliphatic residue of which has 4 to 40 carbon atoms, in an aqueous inorganic acid medium, at a temperature between 0.degree. and 40.degree. C.; the chlorination is advantageously carried out in presence of an inorganic salt.

Abstract: A low density matting structure of improved transverse strength obtained by vertically laying continuous melt-spun thermoplastic macrofilaments (diameter=0.1-1.5 mm) onto a horizontally moving profiled support in overlapping rows of irregularly looped filaments to form a peak and valley three-dimensional structure undulating in its longitudinal and/or transverse direction. The matting articles consist essentially of the melt-spun filaments which are self-bonded or fused at random points of intersection without using any bonding agent or reinforcing inserts, and the resulting matting is especially distinguished by a high transverse strength per unit of surface weight of at least 2 Nm/g and preferably 4 Nm/g.

Abstract: A process for the preparation of an organic peroxide master batch comprising about 20-60% by weight of an organic peroxide and about 40-80% by weight of a polymer capable of being cross-linked by the peroxide, is disclosed. The process comprises contacting particles of such a polymer, having a diameter from about 200 microns to about 20 millimeters, at a temperature from about 15.degree. C. to about 95.degree. C.

Abstract: An improved electrical socket for providing superior electrical and mechanical contact to a mating electrical pin. The socket includes an elongated metallic box which receives the pin contact. An elliptical spring is secured in the box by ear pairs projecting from the opposing ends of the elliptical spring. A pair of cantilevered beams, integral with the top of the box, are bent slightly downward and have their free ends in contact with the ends of the elliptical spring. The cantilevered beams thus form a pair of single leaf springs. The elliptical spring and the cantilevered beams cooperate with each other to provide a suitable force on the inserted pin over a wide range of deflections of the springs.

Abstract: A non-toxic liquid stabilizer comprising, (a) from about 5 to about 35 percent of zinc resinate, (b) from about 5 to about 35 percent of calcium resinate, (c) from about 10 to about 40 percent of non-toxic plasticizer, (d) from about 1 to about 10 percent of a non-toxic antioxidant, and (e) from about 25 to about 75 percent of a non-toxic phosphite, said stabilizer containing from about 0.1 to about 3.5 percent zinc, and from about 0.025 to about 2.28 percent calcium, all weights being based upon the total weight of the stabilizer, is disclosed. Also disclosed is a similar stabilizer which does not contain phosphite and contains from about 25 to about 90 percent of the plasticizer. A method for stabilizing halogenated hydrocarbon resins utilizing the stabilizers of the present invention is also disclosed.

Abstract: A novel temperature indicating device is disclosed comprising: (a) a flat or gradually curved heat-conducting carrier having one or more cavities, each substantially filled with a novel composition of matter (NTICM), as described herein; or in the alternative, with (1) a `classical` composition of matter which changes from opaque to transparent upon a corresponding change from solid to liquid on top of an (2) indicator means located at the bottom of the cavity; said composition of matter, whether novel or not, being substantially without impurities and containing a substantially spherical void space between the bottom of the cavity; and (b) a transparent cover sheet means in sealing engagement with the heat conducting carrier means overlying and above the cavity, which spherical void space acts to magnify the color change if the novel compositions of matter are present or the presence of an indicator means upon melting of the `classical` compositions of matter in the cavity.

Abstract: There is provided a telephone toll restrictor which is adapted to split the telephone line into two separate circuits for isolating the instrument from the central office during dialing. A dialing tone sensor provides signalling information to a programmed microprocessor which determines whether or not the number is permissible. A pair of filters separate the high and low frequencies of the tone and input this information to the microprocessor. If the dialing tones are permissible, then a generator regenerates the tones and passes the tones to the central office for completing the call. Furthermore, the telephone line is then recoupled and the call is permitted. If the call is not permitted, then a holding bridge, which holds the central office while the microprocessor examines the number, is opened by the microprocessor, causing the central office to time out, thus denying access to the caller.

Abstract: The invention relates to a process for the treatment on a circular knitting machine of multifilament yarns with a stream of gaseous fluid under superatmospheric pressure, more particularly air, in which treatment the yarns to be knitted are rendered more or less bulky by subjecting them to a blowing treatment in a zone between the point from which the starting yarns are supplied and the point at which they reach the knitting needles.

Abstract: New and pharmacologically useful tetracyclic compounds are disclosed of the formula (I): ##STR1## and pharmaceutically acceptable non-toxic salts therefor, wherein: (a) R is hydrogen, alkyl of one to six carbons, aralkyl of seven to ten carbons, or an acyl group of one to six carbons;(b) R.sub.1, R.sub.2, R.sub.3 and R.sub.4 each represent hydrogen, hydroxy, halogen, alkyl of one to six carbons, alkoxy of one to six carbons, alkythio of one to six carbons, or trifluromethyl; and(c) R.sub.5 represents hydrogen or an alkyl group of one to six carbons;as well as compositions containing these active compounds and methods of using same. The compounds of the instant invention have a remarkable pharmacological profile--one which clearly indicates the presence of anxiolytic properties with little or no sedative activity. The compounds according to the invention thus possess relatively specific anti-anxiety properties.

Abstract: A novel temperature indicator having a cover layer and including a backing strip with an embossed well stamped therein is provided (in the alternative, the cover layer may be embossed) to form a pocket. The well may contain a matrix carrier which is impregnated with a thermally responsive fusible chemical. The bottom of the well is painted a bright color. If employed, the impregnated matrix is placed over and substantially covers the colored bottom of the well. The top of the well is covered by a transparent film. At a temperature below a predetermined level, the colored bottom of the well is substantially invisible due to the impregnated matrix being opaque, and at temperatures above such predetermined level, the colored bottom of the well is clearly visible due to the transparency of the impregnated matrix upon melting of the chemical. The matrix may be eliminated if the backing strip and/or cover layer is air permeable and if the chemical entirely fills the pocket.

Abstract: Zinc chelates of terephthaloyl-terephthalic/oxalic copolyhydrazides, the oxalic dihydrazide and terephthalic dihydrazide units having a molar ratio in the range of 19:6 to 6:19, as well as the products aftertreated with an oxalic acid solution.