Patents Represented by Attorney Gary D. Schnittgrund
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Patent number: 8336191Abstract: An electronics filter circuit includes an electromechanical resonator that is mounted directly to the surface of a silicon integrated circuit, rather than being a surface mounted or leaded filter can on a circuit board. This filter circuit allows the integrated circuit electronic package to be significantly smaller than a conventional electromechanical resonator package. The electromechanical resonator may be protected during processing and during use with a protective cover that is made of a material such as titanium. The protective cover is attached to the integrated circuit chip.Type: GrantFiled: August 3, 2007Date of Patent: December 25, 2012Assignee: Alfred E. Mann Foundation For Scientific ResearchInventors: Charles L. Byers, Joseph H. Schulman, Gary D. Schnittgrund
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Patent number: 8301266Abstract: A device configured for implantation beneath a patient's skin for the purpose of tissue, e.g., nerve or muscle, stimulation and/or parameter monitoring and/or data communication. Devices in accordance with the invention are comprised of a sealed housing, typically having an axial dimension of less than 60 mm and a lateral dimension of less than 6 mm, containing a power source for powering electronic circuitry within. A placement structure is shown for facilitating placement of the implantable device proximate to neural/muscular tissue.Type: GrantFiled: September 18, 2008Date of Patent: October 30, 2012Assignee: Alfred E. Mann Foundation For Scientific ResearchInventors: Yitzhak Zilberman, Ross Davis, Lee J. Mandell, Joseph H. Schulman
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Patent number: 8177116Abstract: A method of bonding a stainless steel part to a titanium part by heating a component assembly comprised of the titanium part, the stainless steel part, and a laminated titanium-nickel filler material placed between the two parts and heated at a temperature that is less than the melting point of either the stainless steel part or the titanium part. The component assembly is held in intimate contact at temperature in a non-reactive atmosphere for a sufficient time to develop a hermetic and strong bond between the stainless steel part and the titanium part. The bonded component assembly is optionally treated with acid to remove any residual free nickel and nickel salts, to assure a biocompatible component assembly, if implanted in living tissue.Type: GrantFiled: December 6, 2011Date of Patent: May 15, 2012Assignee: Alfred E. Mann Foundation for Scientific ResearchInventors: Guangqiang Jiang, Attila Antalfy
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Patent number: 8155745Abstract: The invention is a system and a method of enabling a person with one or two prosthetic legs to walk [i.e. be gait enabled] by using an implanted microstimulator that activates hip abduction, using a control unit, external coil, and a foot mounted foot switch.Type: GrantFiled: December 24, 2008Date of Patent: April 10, 2012Assignee: Alfred E. Mann Foundation For Scientific ResearchInventors: Daniel R. Merrill, David L. Hankin, Brian R. Dearden
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Patent number: 8140162Abstract: The invention is directed to an apparatus substantially eliminating destructive low-temperature, humidity-enhanced phase transformation of yttria-stabilized zirconia in general, as well as eliminating low-temperature degradation of yttria-stabilized tetragonal zirconia polycrystalline ceramic (Y-TZP). The martensitic-type phase transformation from tetragonal to monoclinic is accompanied by severe strength degradation in a moist environment at low-temperature, specifically at room temperature as well as at body temperature. This class of materials has been chosen as the packaging material for small implantable neural-muscular sensors and stimulators because of the high fracture toughness and high mechanical strength. This destructive phase transformation has been substantially eliminated, thus ensuring the safety of long-term implants, by subjecting the sintered components to post-machining hot isostatic pressing, such that the average grain size is less than about 0.5 microns.Type: GrantFiled: February 23, 2009Date of Patent: March 20, 2012Assignee: Alfred E. Mann Foundation For Scientific ResearchInventors: Guangqiang Jiang, Kate E. Purnell, Gary D. Schnittgrund
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Patent number: 8091765Abstract: A method of bonding a stainless steel part to a titanium part by heating a component assembly comprised of the titanium part, the stainless steel part, and a laminated titanium-nickel filler material placed between the two parts and heated at a temperature that is less than the melting point of either the stainless steel part or the titanium part. The component assembly is held in intimate contact at temperature in a non-reactive atmosphere for a sufficient time to develop a hermetic and strong bond between the stainless steel part and the titanium part. The bonded component assembly is optionally treated with acid to remove any residual free nickel and nickel salts, to assure a biocompatible component assembly, if implanted in living tissue.Type: GrantFiled: January 20, 2006Date of Patent: January 10, 2012Assignee: Alfred E. Mann Foundation For Scientific ResearchInventors: Guangqiang Jiang, Atilla Antalfy
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Patent number: 8055336Abstract: A method of removing an implantable electronic microdevice by an integral removal loop or circumferential ring to facilitate removal of the implanted microdevice without additional surgery. The device is removed by pulling it along the surgically created implantation path. Optionally a radio-opaque tether provides a method of locating the implantable microdevice without additional surgery and attachment of one end of the tether to a radio-opaque marker provides a method of locating the end of the tether to facilitate removal of the implantable microdevice from living tissue.Type: GrantFiled: October 12, 2007Date of Patent: November 8, 2011Assignee: Alfred E. Mann Foundation For Scientific ResearchInventors: Joseph H. Schulman, Yitzhak Zilberman, Kate E. Purnell, Martin J. Vogel, Adam Vogel, legal representative
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Patent number: 8043454Abstract: The invention is a method of making a hermetic via in a ceramic substrate that is comprised of noble metal powder in a glass-free paste that contains an admixture of a particulate phase of niobium pentoxide. The electrically conductive platinum provides excellent electrical conductivity while the niobium pentoxide phase prevents shrinkage of the paste during thermal processing and binds to both the ceramic and the noble metal particulates in the via, thus maintaining a hermetic seal around the via.Type: GrantFiled: January 10, 2011Date of Patent: October 25, 2011Assignee: Alfred E. Mann Foundation For Scientific ResearchInventors: Guangqiang Jiang, Attila Antalfy, Gary D. Schnittgrund
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Patent number: 8024022Abstract: The electrode array is a device for making electrical contacts with cellular tissue or organs. The electrode array includes an assembly of electrically conductive electrodes arising from a substrate where the electrodes are hermetically bonded to the substrate. The electrodes also include an insulating layer which leaves at least one zone or at least one hole exposed for making focused electrical contact with the tissue. A hole passing completely or partially through the electrode may further provide an anchor to the living tissue, thereby stabilizing the array with respect to the tissue being examined. Also, a method of manufacture of an electrode array and associated circuitry is disclosed.Type: GrantFiled: April 28, 2006Date of Patent: September 20, 2011Assignee: Alfred E. Mann Foundation for Scientific ResearchInventors: Joseph H. Schulman, Guangqiang Jiang, Charles L. Byers
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Patent number: 8000803Abstract: The invention is a lead attachment suitable for implantation in living tissue that enables connection of a wire that is comprised of stainless steel to a tack that in turn is bonded to a titanium swage cup, preferably Ti-6Al-4V. The wire is attached by crimping inside a crimping tube, to assure electrical continuity from the wire to the crimping tube. The tack is bonded by swaging a thinned swage ring and is further sealed by welding to swage cup, which is bonded by brazing to ceramic case.Type: GrantFiled: April 6, 2006Date of Patent: August 16, 2011Assignee: Alfred E. Mann Foundation For Scientific ResearchInventor: Alfredo Araujo
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Patent number: 7967869Abstract: Permanent magnets or electromagnets or a combination of such magnets are provided as a method to retain a prosthetic device on an extremity, such as an arm. The prosthesis utilizes the opposing forces, which are developed by virtue of like magnetic poles being in proximity to each other, to urge the prosthesis to remain attached to the extremity. The prosthesis is prevented from rotation by virtue of a centering force that is provided by an attachment magnet in the prosthesis being placed between two implanted magnets. A removable mounting ring is placed over the prosthesis straps to maintain them in proximity to the extremity.Type: GrantFiled: May 23, 2006Date of Patent: June 28, 2011Assignee: Alfred E. Mann Foundation For Scientific ResearchInventors: Joseph H. Schulman, Charles L. Byers
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Patent number: 7908014Abstract: The invention is an antenna for use with an implantable microdevice, such as a microstimulator or microsensor, having a dipole antenna that is formed by ceramic processes on the inner or outer surface of the ceramic case of the microdevice. The antenna receives data transmitted from an external device, and transmits data to an external device. A dipole antenna may be formed from two radiating elements separated by an insulating material. A tuning circuit comprising capacitors and/or inductors is used to obtain resonance in the dipole antenna. In a preferred embodiment, the antenna is formed of a biocompatible material by applying a metal-containing paste to the ceramic case of the microdevice and thermally processing it.Type: GrantFiled: May 5, 2006Date of Patent: March 15, 2011Assignee: Alfred E. Mann Foundation For Scientific ResearchInventors: Joseph H. Schulman, Howard H. Stover, Brian J. Lasater
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Patent number: 7901761Abstract: The invention is a hermetic via in a ceramic substrate that is comprised of noble metal powder in a glass-free paste that contains an admixture of a particulate phase of niobium pentoxide. The electrically conductive platinum provides excellent electrical conductivity while the niobium pentoxide phase prevents shrinkage of the paste during thermal processing and binds to both the ceramic and the noble metal particulates in the via, thus maintaining a hermetic seal around the via.Type: GrantFiled: March 30, 2007Date of Patent: March 8, 2011Assignee: Alfred E. Mann Foundation For Scientific ResearchInventors: Guangqiang Jiang, Attila Antalfy, Gary D. Schnittgrund
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Patent number: 7563279Abstract: A system and method that minimizes plaque accumulation on a stent and thereby restenosis that could require a subsequent invasive medical procedure following stent implantation. The stent, essentially an expandable wire mesh tube comprised of a plurality of integral lattice portions, configured for expansion within a blood vessel of a patient, is formed with an electrically-controlled, biocompatible device as one of its integral lattice portions. In a first implementation, the biocompatible device is under control of an externally-positioned controller which causes the device to emit an ultrasonic wave at a frequency corresponding to the mechanical resonance of the stent and thereby minimize accumulation of plaque. In a second or supplemental implementation, the device is or other portions of the stent are coated with a drug that can be controllably eluted by passing a current through the coating under control of the biocompatible device and the externally-positioned controller.Type: GrantFiled: June 20, 2005Date of Patent: July 21, 2009Assignee: Alfred E. Mann Foundation for Scientific ResearchInventor: Brian J. Lasater
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Patent number: 7519419Abstract: The invention is directed to a material and a method of substantially eliminating destructive low-temperature, humidity-enhanced phase transformation of yttria-stabilized zirconia in general, as well as eliminating low-temperature degradation of yttria-stabilized tetragonal zirconia polycrystalline ceramic (Y-TZP). The martensitic-type phase transformation from tetragonal to monoclinic is accompanied by severe strength degradation in a moist environment at low-temperature, specifically at room temperature as well as at body temperature. This class of materials has been chosen as the packaging material for small implantable neural-muscular sensors and stimulators because of the high fracture toughness and high mechanical strength. This destructive phase transformation has been substantially eliminated, thus ensuring the safety of long-term implants, by subjecting the sintered components to post-machining hot isostatic pressing, such that the average grain size is less than about 0.5 microns.Type: GrantFiled: July 28, 2003Date of Patent: April 14, 2009Assignee: Alfred E. Mann Foundation for Scientific ResearchInventors: Guangqiang Jiang, Kate E. Purnell, Gary D. Schnittgrund
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Patent number: 7450998Abstract: A method for facilitating placement of an implantable device configured for implantation beneath a patient's skin for the purpose of tissue, e.g., nerve or muscle, stimulation and/or parameter monitoring and/or data communication. A placement structure is shown for facilitating placement of the implantable device proximate to neural/muscular tissue.Type: GrantFiled: November 21, 2003Date of Patent: November 11, 2008Assignee: Alfred E. Mann Foundation For Scientific ResearchInventors: Yitzhak Zilberman, Ross Davis, Lee J. Mandell, Joseph H. Schulman
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Patent number: 7435443Abstract: The invention is directed to a method of producing the material that is unaffected by the low-temperature degradation, humidity-enhanced phase transformation typical of yttria-stabilized zirconia, as well as of yttria-stabilized tetragonal zirconia polycrystalline ceramic (Y-TZP). Because of the high fracture toughness and high mechanical strength, this class of materials is widely used, including as implants, such as for the packaging material for small implantable neural-muscular sensors and stimulators. The destructive phase transformation rate is dramatically reduced by coating the surface of the Y-TZP component with dense alumina by a physical vapor deposition process, preferably ion beam assisted deposition.Type: GrantFiled: December 8, 2005Date of Patent: October 14, 2008Assignee: Alfred E. Mann Foundation for Scientific ResearchInventor: Guangqiang Jiang
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Patent number: 7343204Abstract: Apparatus connect electrically conductive wire to a miniature, implantable sensor or stimulator device for detecting electrical signals or stimulating living tissue. The implantable device has an electrically conductive end on its case which is intimately connected to a doorknob electrode for communicating electrical signals between the living tissue and the device by a biocompatible wire. A spring clip removably attaches to the doorknob electrode so that the wire may be easily attached to the doorknob electrode during surgery. An insulating rubber boot, which may be silicone, surrounds the case end, doorknob electrode, and spring clip to isolate the living tissue from the conductive components. The components are biocompatible materials.Type: GrantFiled: June 13, 2005Date of Patent: March 11, 2008Assignee: Alfred E. Mann Foundation For Scientific ResearchInventors: Joseph H. Schulman, Janusz Kuzma
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Patent number: 7331499Abstract: A method of bonding a ceramic part to a metal part by heating a component assembly including the metal part, the ceramic part, and a thin essentially pure interlayer material placed between the two parts heated at a temperature that is greater than the temperature of the eutectic formed between the metal part and the interlayer material, but that is less than the melting point of the interlayer material, the ceramic part or the metal part is disclosed. The component assembly is held in intimate contact at temperature in a non-reactive atmosphere for a sufficient time to develop a hermetic and strong bond between the ceramic part and the metal part. The bonded assembly is optionally treated with acid to remove any residual free nickel and nickel salts to assure a biocompatible assembly for implantation in living tissue.Type: GrantFiled: August 27, 2005Date of Patent: February 19, 2008Assignee: Alfred E. Mann Foundation For Scientific ResearchInventors: Guangqiang Jiang, Kate E. Purnell, Gary D. Schnittgrund
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Patent number: 7297420Abstract: The invention is directed to a material that is unaffected by the low-temperature degradation, humidity-enhanced phase transformation typical of yttria-stabilized zirconia, as well as of yttria-stabilized tetragonal zirconia polyorystalline ceramic (Y-TZP). Because of the high fracture toughness and high mechanical strength, this class of materials is widely used, including as implants, such as for the packaging material for small implantable neural-muscular sensors and stimulators. The destructive phase transformation rate is dramatically reduced by coating the surface of the Y-TZP component with dense alumina by a physical vapor deposition process, preferably ion beam assisted deposition.Type: GrantFiled: August 27, 2004Date of Patent: November 20, 2007Assignee: Alfred E. Mann Foundation For Scientific ResearchInventor: Guangqiang Jiang