Patents Represented by Attorney Gary D. Schnittgrund
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Patent number: 7286883Abstract: Methods are utilized for connecting electrically conductive wire to a miniature, implantable sensor or stimulator device for detecting electrical signals or stimulating living tissue. The implantable device has an electrically conductive end on its case which is intimately connected to a doorknob electrode for communicating electrical signals between the living tissue and the device by a biocompatible wire. A spring clip removably attaches to the doorknob electrode so that the wire may be easily attached to the doorknob electrode during surgery. An insulating rubber boot, which may be silicone, surrounds the case end, doorknob electrode, and spring clip to isolate the living tissue from the conductive components. The components are all biocompatible materials.Type: GrantFiled: June 13, 2005Date of Patent: October 23, 2007Assignee: Alfred E. Mann Foundation For Scientific ResearchInventors: Joseph H. Schulman, Janusz Kuzma
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Patent number: 7271525Abstract: An electronics filter circuit includes an electromechanical resonator that is mounted directly to the surface of a silicon integrated circuit, rather than being a surface mounted or leaded filter can on a circuit board. This filter circuit allows the integrated circuit electronic package to be significantly smaller than a conventional electromechanical resonator package. The electromechanical resonator may be protected during processing and during use with a protective cover that is made of a material such as titanium. The protective cover is attached to the integrated circuit chip.Type: GrantFiled: April 20, 2005Date of Patent: September 18, 2007Assignee: Alfred E. Mann Foundation For Scientific ResearchInventors: Charles L. Byers, Joseph H. Schulman, Gary D. Schnittgrund
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Patent number: 7228624Abstract: The invention is a methods of connecting wire that is suitable to connect electrical devices implanted in a living body. The invention enables manipulation of a narrow wire and a crimping component that are on the order of a millimeter in size. The method utilizes a crimper having a slideably attached connector holder that moves relative to the crimper to position an open end of the crimp connector between the crimp die and the crimp anvil, and a slideably attached wire holder that allows the wire holder to be moved relative to the crimper to position a portion of the wire within the open end of the crimp connector. Small components are positioned with precision using a combination of the user's senses, not necessarily including vision. The method does not require stripping electrical insulation from the wires and is also useful for interconnection of miniaturized non-medical electrical devices.Type: GrantFiled: April 1, 2005Date of Patent: June 12, 2007Assignee: Alfred E. Mann Foundation for Scientific ResearchInventor: Gordon W. Culp
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Patent number: 7178710Abstract: A method of braze bonding a stainless steel part to a titanium part by heating a component assembly comprised of the titanium part, the stainless steel part, and a very thin substantially pure nickel foil filler material placed between the two parts and heated at a temperature that is greater than the temperature of the eutectic formed between the titanium part and the substantially pure nickel filler material, but that is less than the melting point of either the filler material, the stainless steel part, or the titanium part. The component assembly is held in intimate contact at temperature in a non-reactive atmosphere for a sufficient time to develop a hermetic and strong bond between the stainless steel part and the titanium part. The bonded component assembly is optionally treated with acid to remove any residual free nickel and nickel salts, to assure a biocompatible component assembly for implantation in living tissue.Type: GrantFiled: February 16, 2006Date of Patent: February 20, 2007Assignee: Alfred E. Mann Foundation for Scientific ResearchInventors: Guangqiang Jiang, Atilla Antalfy
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Patent number: 7181287Abstract: The invention is directed to an implantable device to enable delivery of drugs to the retina. The device minimizes stress to the retina by virtue of its softness and smooth shape that conform to the retina. Drugs are delivered by osmosis or by the device dissolving. It may be connected to an externally mounted pump and drug reservoir that control the amount of drug. It contains one or more holes that are positioned to deliver drugs to the desired location. Drugs may stimulate the retina to enable vision in blind patients. Drugs may be injected directly inside the eye by a trans-scleral pump and valve drug delivery device.Type: GrantFiled: July 24, 2002Date of Patent: February 20, 2007Assignee: Second Sight Medical Products, Inc.Inventor: Robert Greenberg
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Patent number: 7157150Abstract: A method of bonding a stainless steel part to a titanium part by heating a component assembly comprised of the titanium part, the stainless steel part, and a compact titanium-nickel filler material placed between the two parts and heated at a temperature that is less than the melting point of either the stainless steel part or the titanium part. The compact filler material is made of particles, preferably spheres, of discrete layers of nickel and titanium metal that react with each other and with the stainless and titanium parts to form a strong assembly when thermally processed. The component assembly is held in intimate contact at temperature in a non-reactive atmosphere for a sufficient time to develop a hermetic and strong bond between the stainless steel part and the titanium part.Type: GrantFiled: April 14, 2004Date of Patent: January 2, 2007Assignee: Alfred E. Mann Foundation for Scientific ResearchInventors: Guangqiang Jiang, Attila Antalfy, Gary D. Schnittgrund
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Patent number: 7132754Abstract: A flip chip stack of integrated circuits for minimum volume packaging with interconnected chips attached to one or two sides of a flexible circuit board where stacking arrangements for two, five and six chips are disclosed.Type: GrantFiled: December 16, 2005Date of Patent: November 7, 2006Assignee: Alfred E. Mann Foundation for Scientific ResearchInventor: Siegmar Schmidt
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Patent number: 7071546Abstract: An apparatus and packaging method for stacking a plurality of integrated circuit substrates, i.e., substrates having integrated circuits formed as integral portions of the substrates, which provides interconnection paths through the substrates to simplify electrical connections between the integrated circuits while facilitating minimization of the volume and customization of the three dimensional package size to conform to the available internal space within a housing, e.g., one used in an implantabie device where package volume is at a premium. Furthermore, an internal cavity can be created by the stacked formation that is suitable for mounting of a surface mount device, e.g., a crystal or the like.Type: GrantFiled: March 12, 2003Date of Patent: July 4, 2006Assignee: Alfred E. Mann Foundation for Scientific ResearchInventors: Kate E. Fey, Charles L. Byers, Lee J. Mandell
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Patent number: 7037603Abstract: The invention is directed to a material and a method of producing the material that is unaffected by the low-temperature degradation, humidity-enhanced phase transformation typical of yttria-stabilized zirconia in general, as well as of yttria-stabilized tetragonal zirconia polycrystalline ceramic (Y-TZP). Because of the high fracture toughness and high mechanical strength, this class of materials is widely used, including as implants, such as for the packaging material for small implantable neural-muscular sensors and stimulators. The destructive phase transformation is eliminated by converting the surface to stable cubic or T-prime zirconia by post-densification thermal treatment in a cation-rich milieu.Type: GrantFiled: May 25, 2004Date of Patent: May 2, 2006Assignee: Alfred E. Mann Foundation for Scientific ResearchInventor: Brian J. Lasater
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Patent number: 7022415Abstract: The invention is a method of bonding a ceramic part (6) to a metal part (4) by heating a component assembly (2) comprised of the metal part (4), the ceramic part (6), and a thin laminated interlayer material (8) placed between the two parts and heated at a temperature that is greater than the temperature of the eutectic formed within the laminated interlayer material (8) or between the metal part (4) and the laminated interlayer material (8), but that is less than the melting point of the ceramic part (6) or of the metal part (4). The component assembly (2) is held in intimate contact at temperature in a non-reactive atmosphere for a sufficient time to develop a strong bond between the ceramic part (6) and the metal part (4). The compact interlayer material (8?) may be further comprised of two or more sets of metal alloy spheres (16, 16?) each having distinct compositions.Type: GrantFiled: March 3, 2004Date of Patent: April 4, 2006Assignee: Alfred E. Mann Foundation for Scientific ResearchInventor: Gary D. Schnittgrund
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Patent number: 6997071Abstract: The invention is a method of qualifying an implantable ceramic component made of high-purity dense yttria tetragonal zirconium oxide polycrystal (Y-TZP) by application of non-destructive tests. Specifically, a qualified Y-TZP ceramic component or witness sample is examined by X-ray diffraction to determine the initial monoclinic phase content. The component or witness sample is exposed to steam at 127° C. for a predetermined period of time, preferably six hours. The monoclinic phase content is determined for the post-exposure sample. The absolute difference between the initial monoclinic phase content and the post-exposure monoclinic phase content is calculated by difference. If the difference is less than 2.1% the sample is accepted. In an alternate embodiment, the components that pass the screening test are examined by ultrasonic testing to evaluate soundness of the ceramic component. Any component that presents a flaw of greater than three microns is rejected.Type: GrantFiled: August 29, 2003Date of Patent: February 14, 2006Assignee: Alfred E. Mann Foundation for Scientific ResearchInventors: Guangqiang Jiang, Kate E. Purnell, Gary D. Schnittgrund, Joseph H. Schulman
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Patent number: 6986453Abstract: The invention is a method of bonding a ceramic part to a metal part by heating a component assembly comprised of the metal part, the ceramic part, and a very thin essentially pure interlayer material of a compatible interlayer material placed between the two parts and heated at a temperature that is greater than the temperature of the eutectic formed between the metal part and the metal interlayer material, but that is less than the melting point of either the interlayer material, the ceramic part or the metal part. The component assembly is held in intimate contact at temperature in a non-reactive atmosphere for a sufficient time to develop a hermetic and strong bond between the ceramic part and the metal part. The bonded component assembly is optionally treated with acid to remove any residual free nickel and nickel salts, to assure a biocompatible component assembly for implantation in living tissue.Type: GrantFiled: November 13, 2003Date of Patent: January 17, 2006Assignee: Alfred E. Mann Foundation for Scientific ResearchInventors: Guangqiang Jiang, Kate E. Purnell, Gary D. Schnittgrund
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Patent number: 6949253Abstract: An implantable biocompatible microchip drug delivery substrate is coated with a thin film of ultra-nanocrystalline diamond; assuring that the device is biocompatible and impermeably sealed, to prevent the substrate from being dissolved by the living tissue and to protect the drugs from premature release or undesired reaction with the body fluids. The coating is selectively patterned by doping to create electrically conductive areas that can be used as an electrically activated release mechanism for drug delivery. The conformal ultra-nanocrystalline diamond coating uniformly covers the device, providing relief from sharp edges and producing a strong, uniformly thick impermeable coating around sharp edges and on high aspect-ratio parts. The ultra-nanocrystalline diamond coating provides a conformal coating on the biocompatible device, which is of approximately uniform thickness around sharp corners and on high aspect-ratio parts.Type: GrantFiled: August 5, 2003Date of Patent: September 27, 2005Assignee: Second Sight Medical Products, Inc.Inventors: Robert J. Greenberg, Brian V. Mech
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Patent number: 6947782Abstract: The invention discloses apparatus for connecting electrically conductive wire to a miniature, implantable sensor or stimulator device for detecting electrical signals or stimulating living tissue. The implantable device has an electrically conductive end on its case which is intimately connected to a doorknob electrode for communicating electrical signals between the living tissue and the device by a biocompatible wire. A spring clip removably attaches to the doorknob electrode so that the wire may be easily attached to the doorknob electrode during surgery. An insulating rubber boot, which may be silicone, surrounds the case end, doorknob electrode, and spring clip to isolate the living tissue from the conductive components. The components are all biocompatible materials.Type: GrantFiled: October 4, 2001Date of Patent: September 20, 2005Assignee: Alfred E. Mann Foundation for Scientific ResearchInventors: Joseph H. Schulman, Janusz Kuzma
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Patent number: 6935897Abstract: A connector (1) and method of making electrical connection between an electrical conductor (7, 11) and a removable electrical device (2). The connector (7, 11) is an elastic material, such as silicone, that is both compatible with the environment and is an electrical insulator. It forces contact between the electrical device (2) and integral contacts (10, 13) in the connector (1) by virtue of its elasticity. The electrodes (4, 6) and the electrical connections are protected from the environment to avoid electrical leakage or corrosion of the electrodes (4, 6).Type: GrantFiled: January 16, 2004Date of Patent: August 30, 2005Assignee: Alfred E. Mann Foundation for Scientific ResearchInventors: David L. Canfield, Charles L. Byers, Gary D. Schnittgrund
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Patent number: 6829508Abstract: An electrically sensing and stimulating outer sheath for ensuring accurate surgical placement of a microsensor or a microstimulator near a nerve in living tissue is disclosed. The electrically sensing outer sheath may also be used to verify the function of the microstimulator or microsensor during surgical placement but before the outer sheath is removed. In the event that the microstimulator is not optimally placed near the nerve, or if the microstimulator is malfunctioning, this can be determined prior to removal of the outer sheath, thus reducing the possibility of nerve or tissue damage that might be incurred during a separate operation to remove the microstimulator.Type: GrantFiled: April 4, 2002Date of Patent: December 7, 2004Assignee: Alfred E. Mann Foundation for Scientific ResearchInventors: Joseph H. Schulman, Ralph M. Weisner, David L. Canfield, Kate E. Fey, Charles L. Byers
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Patent number: 6821154Abstract: A connector and method of making electrical connection between an electrical conductor and a removable electrical device. The connector is an elastic material, such as silicone, that is both compatible with the environment and is an electrical insulator. It forces contact between the electrical device and integral contacts in the connector by virtue of its elasticity. The electrodes and the connections are protected from the environment to avoid electrical leakage or corrosion of the electrodes.Type: GrantFiled: October 3, 2003Date of Patent: November 23, 2004Assignee: Alfred E. Mann Foundation for Scientific ResearchInventors: David L. Canfield, Charles L. Byers
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Patent number: 6792314Abstract: An implantable miniature eyelid electrode apparatus that causes a paralyzed eyelid to close or open by passing an electrical stimulating current to a nerve or muscle, is comprised of a longitudinally flexible, nonconductive body containing electrodes that pass an electrical signal to the nearby nerve or muscle, which closes or opens the eyelid. The apparatus is electrically actuated by a source that may be located remotely from the apparatus. The electrical signal passes along wires from the source to the apparatus. The apparatus is biocompatible with the environment in the living tissue and is electrically insulated from the surrounding tissue, except where the electrodes contact the living tissue. The apparatus is very small and is not obvious to visual inspection when implanted.Type: GrantFiled: May 31, 2002Date of Patent: September 14, 2004Assignee: Alfred E. Mann Foundation for Scientific ResearchInventors: Charles L. Byers, Kate E. Fey, Ralph M. Weisner, Gary D. Schnittgrund
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Patent number: 6738672Abstract: The invention discloses methods of making electrical connections in living tissue between an electrically conductive wire and an implantable miniature device. The device may either stimulate muscles or nerves in the body or detect signals and transmit these signals outside the body or transmit the signals for use at another location within the body. The device is comprised of an electrically insulating or electrically conductive case with at least one electrode for transmitting electrical signals. The electrodes and the wire-electrode connections are protected from the aggressive environment within the body to avoid corrosion of the electrode and to avoid damage to the living tissue surrounding the device.Type: GrantFiled: October 4, 2001Date of Patent: May 18, 2004Assignee: The Alfred E. Mann Foundation for Scientific ResearchInventors: Joseph H. Schulman, Kate E. Fey, Charles L. Byers, Yitzhak Zilberman, Robert D. Dell
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Patent number: 6467214Abstract: The invention is a fishing float and method of using the same that permits a positive attachment to a fishing line and that provides secure, easy and rapid attachment of the fishing line to the float and that allows the weight of the float to be readily changed thereby controlling the casting and float characteristics of the float.Type: GrantFiled: March 28, 2001Date of Patent: October 22, 2002Inventor: Guy DeFrisco