Patents Represented by Attorney Geoffrey G. Dellenbaugh

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  • Fungicidal 1-(-2-aryl-4,5-disubstituted-1,3-dioxolan-2-ylmethyl)-1H-imidazoles and 1H-1,2,4-triazoles
    Patent number: 4602010
    Abstract: Novel 1-(1,3-dioxolan-2-ylmethyl)-1H-imidazoles and 1H-1,2,4-triazoles wherein the 1,3-dioxolane ring is substituted in the 4- and in the 5-positions, said compounds having useful antimicrobial properties.
    Type: Grant
    Filed: November 7, 1983
    Date of Patent: July 22, 1986
    Assignee: Janssen Pharmaceutica, N.V.
    Inventors: Jan Heeres, Leo Backx, Willy Van Laerhoven, Elmar Sturm
  • Substituted 2-amino-4(1H)pyridones, 7-pyrrolo[1,2-a]pyridinones, 2-quinolizinones, 7-thiazolo[3,2-a]pyridinones and 2-pyrido[1,2-a]azepinones as vasodilators and bronchodilators
    Patent number: 4602013
    Abstract: Substituted 2-amino-4(1H)pyridones are provided which are renal vasodilators and bronchodilators.
    Type: Grant
    Filed: February 8, 1984
    Date of Patent: July 22, 1986
    Assignee: Ortho Pharmaceutical Corporation
    Inventor: Jack B. Jiang
  • Fungicidal 1-(2-aryl-2-R-ethyl)-1H-1,2,4-triazoles
    Patent number: 4598085
    Abstract: Novel compounds of the class of 1-(2-aryl-2-R-ethyl)-1H-1,2,4-triazoles having fungicidal and plant-growth regulating properties.
    Type: Grant
    Filed: January 21, 1982
    Date of Patent: July 1, 1986
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Jan Heeres, Leo J. J. Backx, Joseph A. Mostmans
  • Substituted dioxopyridopyrimidines
    Patent number: 4596805
    Abstract: Substituted dioxopyridopyrimidines are provided which are useful as calcium antagonists and anti-hypertensive agents.
    Type: Grant
    Filed: June 13, 1984
    Date of Patent: June 24, 1986
    Assignee: Ortho Pharmaceutical Corporation
    Inventor: Jack B. Jiang
  • N-(4-piperidinyl) bicyclic condensed 2-imidazolamine derivatives
    Patent number: 4588722
    Abstract: Novel N-(4-piperidinyl) bicyclic condensed 2-imidazolamine derivatives having antihistaminic properties which compounds are useful in the treatment of allergic diseases.
    Type: Grant
    Filed: October 15, 1984
    Date of Patent: May 13, 1986
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Frans E. Janssens, Joseph L. G. Torremans, Jozef F. Hens, Theophilus T. J. M. Van Offenwert
  • Bursopoietin
    Patent number: 4584284
    Abstract: A synthetic peptide which possesses the ability to specifically induce the differentiation of precursor B cells into mature B-cells capable of producing antibody.
    Type: Grant
    Filed: January 31, 1985
    Date of Patent: April 22, 1986
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Tapan Audhya, Daniel J. Kroon, George Heavner, Gideon Goldstein
  • Aiding the regression of neoplastic disease with 2,3,5,6-tetrahydro-6-phenylimidazo[2,1-b]thiazole
    Patent number: 4584305
    Abstract: Process of aiding regression and palliation of neoplastic disease in animal and human hosts comprising systemic administration to phenylimidazo[2,1-b]thiazole or a nontoxic acid addition salt thereof. Preferably the active ingredient is administered in a sufficient amount to provide dosages over the range from about 1 mg to about 5 mg/kg of body weight of the host.
    Type: Grant
    Filed: February 2, 1981
    Date of Patent: April 22, 1986
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Josephus Brugmans, William Pollack, Paul A. J. Janssen, Daniel Tripodi
  • [[Bis(aryl)methylene]-1-piperidinyl]alkyl-pyrimidinones useful for treating psychotropic disorders
    Patent number: 4581171
    Abstract: Novel [[bis(aryl)methylene]-1-piperidinyl]alkyl-pyrimidinones, wherein the pyrimidinone-ring is embraced within a bicyclic system, being useful compounds in the treatment of psychosomatic disorders.
    Type: Grant
    Filed: September 27, 1984
    Date of Patent: April 8, 1986
    Assignee: Janssen Pharmaceutica, N.V.
    Inventors: Ludo E. J. Kennis, Jan Vandenberk, Josephus C. Mertens
  • N-(Bicyclic heterocyclyl)-4-piperidinamines
    Patent number: 4556660
    Abstract: Novel N-(bicyclic heterocyclyl)-4-piperidinamines having antihistaminic and serotonin-antagonistic properties which are useful in the treatment of allergic diseases.
    Type: Grant
    Filed: April 22, 1983
    Date of Patent: December 3, 1985
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Frans E. Janssens, Joseph L. G. Torremans, Jozef F. Hens, Theophilus T. J. M. Van Offenwert
  • 1H-Indol-3-yl containing 1,3-dimethyl-1H-purine-2,6-diones
    Patent number: 4548939
    Abstract: 1H-Indol-3-yl containing 1,3-dimethyl-1H-purine-2,6-diones having psychotropic activity.
    Type: Grant
    Filed: October 1, 1984
    Date of Patent: October 22, 1985
    Assignee: Janssen Pharmaceutica N. V.
    Inventors: Ludo E. J. Kennis, Jan Vandenberk, Jozef M. Boey
  • 5-H-1,3,4-thiadiazolo[3,2-a]pyrimidin-5-one compounds
    Patent number: 4548938
    Abstract: Novel 5H-thiazolo- and 5H-1,3,4-thiadiazolo[3,2-a]pyrimidin-5-one and 3,4-dihydro-2H,6H-pyrimido[2,1-b] [1,3]-thiazin-6-one derivatives, which compounds are useful psychotropic agents.
    Type: Grant
    Filed: February 19, 1985
    Date of Patent: October 22, 1985
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Ludo E. J. Kennis, Josephus C. Mertens
  • Conformationally restricted thymopentin-like compounds
    Patent number: 4547489
    Abstract: Immunoregulating peptides are disclosed which are cyclic peptides similar to thymopentin. These peptides are useful for their effects on the immune system, especially the treatment of thymic deficiencies.
    Type: Grant
    Filed: June 11, 1984
    Date of Patent: October 15, 1985
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Gideon Goldstein, George Heavner, Tapan Audhya, Foe-Siong Tjoeng
  • Process for the protection of wood and coatings against deterioration by microorganisms
    Patent number: 4542146
    Abstract: The agents protect wood and coatings against deterioration by microorganisms. The agents contain at least one compound of the formula ##STR1## wherein X is nitrogen or a CH group and R.sub.1 is a radical of the formula ##STR2## wherein Ar, R and Z are as defined in claim 1, or an acid addition salt thereof.
    Type: Grant
    Filed: November 2, 1983
    Date of Patent: September 17, 1985
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Josef Van Gestel, Benedikt Duytschaever, Rene Muntwyler, Max Scharer
  • 1-(2-Aryl-2-halo-1-ethenyl)-1H-azoles, and anticonvulsant use thereof
    Patent number: 4539325
    Abstract: 1-(2-Aryl-2-halo-1-ethenyl)-1H-azoles having anticonvulsant properties which are particularly useful in the treatment of generalized forms of epilepsy.
    Type: Grant
    Filed: July 12, 1984
    Date of Patent: September 3, 1985
    Assignee: Janssen Pharmaceutica N.V.
    Inventor: Jan Heeres
  • [[Bis(aryl)methylene]-1-piperidinyl]alkyl-pyrimidinones
    Patent number: 4533665
    Abstract: Novel [[bis(aryl)methylene]-1-piperidinyl]alkyl-pyrimidinones, wherein the pyrimidinone-ring is embraced within a bicyclic system, being useful compounds in the treatment of psychosomatic disorders.
    Type: Grant
    Filed: September 27, 1984
    Date of Patent: August 6, 1985
    Assignee: Janssen Pharmaceutica
    Inventors: Ludo E. J. Kennis, Jan Vandenberk, Josephus C. Mertens
  • Heterocyclic derivatives of (4-aryloxymethyl-1,3-dioxolan-2-yl)methyl-1H-imidazoles and 1H-1,2,4-triazoles
    Patent number: 4533550
    Abstract: Novel heterocyclic derivatives of (4-aryloxymethyl-1,3-dioxolan-2-yl)methyl-1H-imidazoles and 1H-1,2,4-triazoles, useful as antifungal and antibacterial agents.
    Type: Grant
    Filed: August 27, 1981
    Date of Patent: August 6, 1985
    Assignee: Janssen Pharmaceutica, N.V.
    Inventors: Jan Heeres, Joseph H. Mostmans
  • Pyrimido[2,1-b][1,3]-thiazines
    Patent number: 4529727
    Abstract: Novel 5H-thiazolo- and 5H-1,3,4-thiadiazolo[3,2-a]-pyrimidin-5-one and 3,4-dihydro-2H,6H-pyrimido[2,1-b][1,3]-thiazin-6-one derivatives, which compounds are useful psychotropic agents.
    Type: Grant
    Filed: February 2, 1984
    Date of Patent: July 16, 1985
    Assignee: Janssen Pharmaceutical, N.V.
    Inventors: Ludo E. J. Kennis, Josephus C. Mertens
  • Antimicrobial imidazole derivatives
    Patent number: 4524110
    Abstract: The invention is concerned with novel dithioketal derivatives of 1-(2-aryl-2-oxoethyl)-1H-imidazoles and sulfones and sulfoxides derived therefrom, said compounds being useful as antimicrobial agents.
    Type: Grant
    Filed: September 28, 1984
    Date of Patent: June 18, 1985
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Jan Heeres, Leo J. J. Backx, Joseph H. Mostmans
  • (Piperidinylalkyl) quinazoline derivatives
    Patent number: 4522945
    Abstract: Novel quinazoline derivatives, comprising in the heterocyclic part of their quinazoline nucleus at least one carbonyl or thiocarbonyl group and a particularly substituted piperidinyl-alkyl side chain, said compounds being potent serotonin-antagonists.
    Type: Grant
    Filed: March 26, 1982
    Date of Patent: June 11, 1985
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Jan Vandenberk, Ludo Kennis, Marcel Van der Aa, Albert Van Heertum
  • Hybrid cell line for producing monoclonal antibody to human helper T cells
    Patent number: 4515895
    Abstract: Hybrid cell line for production of monoclonal antibody to an antigen found on all normal human helper T cells. The hybrid is formed by fusing splenocytes from immunized CAF.sub.1 mice with P3X63Ag8U1 myeloma cells. Diagnostic and therapeutic uses of the monoclonal antibody are also disclosed.
    Type: Grant
    Filed: October 4, 1982
    Date of Patent: May 7, 1985
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Patrick C. Kung, Gideon Goldstein