Abstract: Desmycinosyl derivatives of 12,13-desepoxy-12,13-dehydro antibiotic AR-5 component 1 and 12,13-desepoxy-12,13-dehydro antibiotic AR-5 component 2 are useful antibacterial agents and may be converted to other such agents by processes analogous to those generally known in the art.

Abstract: The Antiboitic AR-5 complex is elaborated by a novel species of the Micromonospora; namely, Micromonospora polytrota. The microorganism also elaborates a number of minor components including the gentamicin complex and a complex of anthroquinone antibiotics.

Abstract: A telescoping electric hair curling iron includes a molded hollow handle of plastic material having front and rear openings and a longitudinally extending thumb-operated cantilever spring element integrally molded as part of the handle wall. The forward end of the cantilever spring element is downwardly bent to form a depressible thumb button immediately adjacent the front handle opening for operating a spring-biased elongated hair gripping clip pivotally mounted on an electrically heated hair curling rod arranged for slidable telescopic movement through the front opening between a retracted storage position within the handle and an extended operative position outside the handle when the curling rod is in the operative position. The curling rod as heated by a PTC heating element therein. A swivel cord connector is mounted on the inner end of the curling rod and is slidable therewith within the handle and in the retracted position of the curling rod extends out the rear handle opening.

Abstract: Novel macrolide antibacterial derivatives of the components of the Antibiotic AR-5-complex are disclosed herein. The invention specifically relates to compounds wherein the macrolide ring and/or the two attached sugars are derivatized. Also disclosed are methods for the preparation of the derivatives and methods for the use thereof.

Abstract: Disclosed herein are certain imidazo[1,5-a]pyridines, and pharmaceutical compositions containing them as the active ingredient for treatment and promotion of healing of peptic ulcer disease by virtue of their antisecretory and cytoprotective properties.

Abstract: Described are D-(threo)-1-aryl-2-acylamido-3-fluoro-1-propanol esters and salts thereof, methods for their preparation, and methods for their use as antibacterial agents.

Abstract: This invention relates to 5-phenyl-1,3-alkano-1,2,3,4,4a,9b-hexahydropyrido [4,3-b]indoles which are antidepressants useful in the treatment of mental depression.

Abstract: A microorganism of the genus Acetinoplanes produces a novel complex of polyene antibiotics herein designated collectively Antibiotic 67-121 (and sometimes referred to as the Antibiotic 67-121 complex). The individual components are designated Antibiotic 67-121A, Antibiotic 67-121B, Antibiotic 67-121C and Antibiotic 67-121D. The individual components have ultraviolet spectra characteristic of heptaenes. Further, they are orally active against a variety of strains of Candida albicans including many clinical isolates thereof.

Abstract: There are disclosed herein certain 1,2,4-triazolo-[4,3-a]pyridine compounds which are useful in the treatment of peptic ulcer diseases.

Abstract: There are disclosed herein certain 1,3,4-triazolo[1,5-a]pyridine compounds which are useful in the treatment of peptic ulcer diseases.

Abstract: The AR-5-3 Complex consisting of four macrolide antibiotics is elaborated by a mutant strain of Micromonospora polytrota. The antibiotics exhibit substantial activity against gram positive bacteria in vitro and in vivo.

Abstract: This invention relates to esters of 7 halo-substituted 8-hydroxy-3 methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines, processes for the preparation thereof, and pharmaceutical compositions containing them. The novel compounds of this invention show neuroleptic, antidepressive and antiaggressive activity.

Abstract: The microorganisms Micromonospora inyoensis 1550F-1G and M. purpurea strain 1124 each microbiologically convert tobramycin, kanamycin A, kanamycin B and dibekacin to their respective 3"-N-methyl and 3"-N-methyl-4"-C-methyl derivatives. The derivatives exhibit significant activity against representative gram positive and gram negative bacteria and may also be converted to other derivatives which have significant antibacterial activity.

Abstract: Described is a novel process for the preparation of penems and carbapenems useful as antibacterial agents which comprises the reaction of an appropriate 4-substituted-azetidine-2-one with an acid halide in the presence of a tertiary amine and an alkaline earth metal carbonate, followed by reaction of the thereby formed 1-imido-4-substituted-azetidine-2-one with a trialkyl phosphite.Also described are novel penems useful as antibacterials which are prepared by the described process.

Abstract: There is disclosed an electrical connector system for a device powered by high current comprising a plug with two high current female contacts and one low current female contact, a socket in the device having two high current male contacts and one low current male contact. The high current contacts are longer than the low current contact so that when the plug is inserted, the high current contacts make connection before the low current contact and when the plug is removed the low current contact is disconnected first, breaking the circuit and preventing arcing. The high current contacts in the socket are electrically connected to the electrical device by a solid-state switch wherein the control gate is operated by the low current contact.

Abstract: There is disclosed an electric cord mechanical interlock system which prevents the user from removing or inserting the cord of an electric appliance when the appliance is switched on thus preventing arcing across the contacts. Arcing is prevented by providing an extension as part of the on-off switch control which, when the switch is off, engages and raises a flexible arm containing a pin, allowing the plug to be inserted or removed.

Abstract: Disclosed herein are certain 1-substituted-4-aryl-1,2,5,6-tetrahydro and hexahydro triazolo pyridines which are useful as analgesics.

Abstract: Described are transition metal salt complexes of available neighboring amino and hydroxyl group pairs in polyamino organic compounds, their preparation, and use as intermediates in the preparation of selectively N-blocked polyamino organic compounds.