Patents Represented by Attorney, Agent or Law Firm Grant Patent Services
  • Patent number: 8153444
    Abstract: A chromatographic specific binding assay strip device, comprising: a non-permeable platform strip; a permeable membrane testing strip positioned on top of said non-permeable platform strip, with the testing strip comprising at least one capture reagent site containing a capture reagent for at least one specific analyte, a sample receiving pad positioned on top of and at a proximal end of the non-permeable platform strip, with the sample receiving pad having contact with a proximal end of said permeable membrane testing strip, a reservoir pad positioned on top of and at a distal end of said non-permeable membrane testing strip, with the reservoir pad having contact with a proximal end of said permeable membrane test strip; a supporting strip attached to and extending from the proximal end of said non-permeable platform strip; and a conjugate pad positioned on said supporting strip, said conjugate pad comprising a semi-permeable membrane containing a colorant conjugate.
    Type: Grant
    Filed: March 18, 2009
    Date of Patent: April 10, 2012
    Assignee: Auric Enterprises, LLC
    Inventors: Leslie Kirkegaard, Glen Ford
  • Patent number: 7951227
    Abstract: This disclosure teaches a composition and process which makes it possible to remove floating particulates or prevent the dissemination or particulates, by the misting of a solution that readily captures any particulate material in the air. More specifically, the present disclosure teaches the composition and use of aromatic compounds that are semi-volatile organic compounds (SVOCs) or slow evaporators in water-based carriers with surfactants as the misting/fogging agent for dust suppression. The particulate material is lowered to surfaces and removed by vacuuming, damp-wiping or using a dry cloth with a cationic charge (static cloth). This method can be achieved with neutral air pressure differentials in the work areas.
    Type: Grant
    Filed: June 4, 2008
    Date of Patent: May 31, 2011
    Inventors: Greg Weatherman, Marcia Celusnek Cash
  • Patent number: 7910381
    Abstract: A chromatographic specific binding assay strip device, comprising: a non-permeable platform strip; a permeable membrane testing strip positioned on top of said non-permeable platform strip, with the testing strip comprising at least one capture reagent site containing a capture reagent for at least one specific analyte, a sample receiving pad positioned on top of and at a proximal end of the non-permeable platform strip, with the sample receiving pad having contact with a proximal end of said permeable membrane testing strip, a reservoir pad positioned on top of and at a distal end of said non-permeable membrane testing strip, with the reservoir pad having contact with a proximal end of said permeable membrane test strip; a supporting strip attached to and extending from the proximal end of said non-permeable platform strip; and a conjugate pad positioned on said supporting strip, said conjugate pad comprising a semi-permeable membrane containing a colorant conjugate.
    Type: Grant
    Filed: March 5, 2008
    Date of Patent: March 22, 2011
    Assignee: BioAssay Works
    Inventors: Glen Ford, Leslie Kirkegaard
  • Patent number: 7771955
    Abstract: Compositions and methods are taught for directing the orientation of an immobilized capture biomolecule on a hydrophobic membrane. The method comprises layering at least one tie layer on a hydrophobic membrane, adding an amine functional layer on top of at least one tie layer; and attaching an alignment biomolecule to the amine functional layer. The alignment biomolecule has the ability to either capture a target biomolecule itself and thus be considered a capture biomolecule, or bind and orient the immobilized capture biomolecule so as to maximize the binding activity of the immobilized capture biomolecule. In one embodiment, a nickel-coordinated amine functional layer binds with a histidine-tagged alignment biomolecule. In another embodiment, an amine functional layer reacts, via tyrosinase catalysis, with a tyrosine residue in an alignment biomolecule.
    Type: Grant
    Filed: June 6, 2006
    Date of Patent: August 10, 2010
    Assignee: University of Maryland
    Inventors: Timothy Alan Barbari, Sufi Rizwan Ahmed
  • Patent number: 7629127
    Abstract: This disclosure teaches a method and composition for detecting the presence of class specific antibodies reactive with analytes such as bacteria, allergens, autoimmune antigens, viral proteins, haptens, and carbohydrates by lateral flow techniques. In one embodiment of the disclosure, a test sample is added to the test strip, which then migrates to the site of the immobilized allergens, thereby forming a first antibody IgE-allergen complex. A chase release buffer is added upstream to or from the site of the labeled anti-IgE antibodies, which is itself upstream from the sample site. The anti-IgE antibodies migrate downstream to the site of immobilized first complex, thereby forming a second complex indicating the presence of class specific IgE antibodies in the test specimen. In another embodiment of the disclosure, a liquid form of the labeled anti-IgE antibodies can be added to the test strip after the first complex has been formed.
    Type: Grant
    Filed: January 21, 2005
    Date of Patent: December 8, 2009
    Assignee: Dexall Biomedical Labs, Inc.
    Inventor: Thomas T. Hubscher
  • Patent number: 7427076
    Abstract: A base tool caddy for janitorial cleaning supplies is disclosed. The tool caddy has an inner circular element which can be in the shape of a cylinder. This inner circular element fits around the base of a standard commercial trash barrel. The inner circular element has an inwardly disposed lip that is designed to fit between the bottom of a commercial trash barrel and the top of the trash barrel's standard commercial wheeled dolly thereby securing the tool caddy to the trash barrel, dolly combination. The inner circular element has one or more outwardly disposed compartments designed to hold janitorial tools and supplies. These outwardly disposed compartments may be configured to serve as a bumper, thereby protecting walls and other surfaces from being marked by the trash barrel. The outwardly disposed compartments may incorporate a stabilizing edge to prevent the trash barrel from rolling when laid on its side.
    Type: Grant
    Filed: March 20, 2006
    Date of Patent: September 23, 2008
    Inventor: David Christopher Gwin
  • Patent number: 7232576
    Abstract: A lozenge for the treatment of Streptococcus Group A infections of the mouth, throat, and nasal passage is disclosed which comprises a lytic enzyme composition specific for Streptococcus Group A and a lozenge carrier for delivering the lytic enzyme.
    Type: Grant
    Filed: November 25, 2003
    Date of Patent: June 19, 2007
    Assignees: New Horizons Diagnostics Corp, Rockefeller University
    Inventors: Vincent Fischetti, Lawrence Loomis
  • Patent number: 7169408
    Abstract: The present invention discloses a composition for dermatological infections by the use of a lytic enzyme in a carrier suitable for topical application to dermal tissues. The method for the treatment of dermatological infections comprises administering a composition comprising effective amount of a therapeutic agent, with the therapeutic agent comprising a lytic enzyme produced by infecting a bacteria with phage specific for that bacteria.
    Type: Grant
    Filed: June 20, 2003
    Date of Patent: January 30, 2007
    Assignees: New Horizons Diagnostics Corp., Rockefeller University
    Inventors: Vincent Fischetti, Lawrence Loomis
  • Patent number: 7141241
    Abstract: The present invention relates to an oral delivery system containing a bacteriophage associated lysin enzyme for the treatment of [Streptococcus pneumoniae and] Hemophilus influenzae sinus/nasal infections.
    Type: Grant
    Filed: February 8, 2002
    Date of Patent: November 28, 2006
    Assignees: New Horizons Diagnostics Corp, Rockefeller University
    Inventors: Vincent Fischetti, Lawrence Loomis
  • Patent number: 7140946
    Abstract: The present invention discloses a retractable coiled toy, made of a material having a memory, which has a handle integral with the coil or body of the toy. The slinger is preferably made out of polyurethane, a coiled steel, other plastics or some other material which has memory. The present invention discloses a number of methods for using the coiled toy. The Slinger can be used to wrap around the wrist, like a bracelet. In another use, the slinger may be used as a lasso.
    Type: Grant
    Filed: November 3, 2000
    Date of Patent: November 28, 2006
    Inventor: Michael F Marlin
  • Patent number: 7063837
    Abstract: The present invention discloses a method and composition for the treatment of bacterial infections by the parenteral introduction of at least one lytic enzyme produced by a bacteria infected with a bacteriophage specific for that bacteria and an appropriate carrier for delivering the lytic enzyme into a patient. The injection can be done intramuscularly, subcutaneously, or intravenously.
    Type: Grant
    Filed: July 19, 2001
    Date of Patent: June 20, 2006
    Assignees: New Horizons Diagnostics Corp, Rockefeller University
    Inventors: Vincent Fischetti, Lawrence Loomis
  • Patent number: 7014850
    Abstract: A nasal spray for treating a streptococcal infection is disclosed. The spray comprises an effective amount of a lysin enzyme genetically coded for by a C1 bacteriophage capable of infecting a group C Streptococcal bacteria, and a nasal spray carrier for delivering said lysin enzyme to a mouth, throat, or nasal passage.
    Type: Grant
    Filed: February 8, 2002
    Date of Patent: March 21, 2006
    Assignees: New Horizons Diagnostics Corp, Rockefeller University
    Inventors: Vincent Fischetti, Lawrence Loomis
  • Patent number: 6936244
    Abstract: A composition for treatment of bacterial infections of the eye is disclosed which comprises a lytic enzyme composition specific for the infecting bacteria, and a carrier for delivering said lytic enzyme. The carrier for delivering at least one lytic enzyme to the eye may be but is not limited to the use of an isotonic solution.
    Type: Grant
    Filed: May 14, 2002
    Date of Patent: August 30, 2005
    Assignees: New Horizons Diagnostics Corp, Rockefeller University
    Inventors: Vincent Fiochetti, Lawrence Loomie
  • Patent number: 6899874
    Abstract: A composition for treatment of bacterial infections of the eye is disclosed which comprises a lytic enzyme composition specific for the infecting bacteria, and a carrier for delivering said lytic enzyme. The carrier for delivering at least one lytic enzyme to the eye may be but is not limited to the use of an isotonic solution.
    Type: Grant
    Filed: May 1, 2002
    Date of Patent: May 31, 2005
    Assignees: New Horizons Diagnostics Corporation, Rockefeller University
    Inventors: Vincent Fischetti, Lawrence Loomis
  • Patent number: 6893635
    Abstract: A method for treating a streptococcal infection is disclosed using a nasal spray. The spray comprises an effective amount of a lysin enzyme genetically coded for by a C1 bacteriophage capable of infecting a group C Streptococcal bacteria, and a nasal spray carrier for delivering said lysin enzyme to a mouth, throat, or nasal passage.
    Type: Grant
    Filed: February 8, 2002
    Date of Patent: May 17, 2005
    Assignees: New Horizons Diagnostics Corp, Rockefeller University
    Inventors: Vincent Fischetti, Lawrence Loomis
  • Patent number: 6881403
    Abstract: A tampon for treatment of Streptococcus Group B infections of the vagina is disclosed which comprises a lytic enzyme composition specific for the infecting bacteria, and a carrier for delivering the lytic enzyme.
    Type: Grant
    Filed: March 25, 2002
    Date of Patent: April 19, 2005
    Assignees: New Horizons Diagnostic, Corp, Rockefeller University
    Inventors: Vincent Fischetti, Lawrence Loomis
  • Patent number: 6876786
    Abstract: An optical fiber sensor system comprising of an optical fiber including plurality of sensitive elements, each sensitive element has characteristic spectral band which in normal undisturbed condition lies in a first wavelength range and, under an influence of some specified condition to be detected, shifts to a second wavelength range; first and second wavelength ranges do not overlap. Means for probing an optical transmission or reflection of the fiber operate within second wavelength range to monitor the changes of the transparency or reflectivity of the fiber caused by the shift of characteristic spectral band into the second wavelength range. The invention provides means for distributed monitoring of equipment or construction structures and detection of specified conditions and can provide alarm signal when the specified conditions become effective.
    Type: Grant
    Filed: October 2, 2002
    Date of Patent: April 5, 2005
    Assignee: Cicese-Centro de Investigation
    Inventors: Mikhail Chliaguine, Vassili Spirine, Serguei Miridonov, Francisco Javier Mendieta Jimenez, Enrique Mitrani Abenchuchan
  • Patent number: D650866
    Type: Grant
    Filed: July 23, 2010
    Date of Patent: December 20, 2011
    Inventor: Peer Clahsen
  • Patent number: D664215
    Type: Grant
    Filed: August 17, 2011
    Date of Patent: July 24, 2012
    Inventor: Peer Clahsen
  • Patent number: D666865
    Type: Grant
    Filed: April 26, 2011
    Date of Patent: September 11, 2012
    Assignee: Base Brands
    Inventors: Patrick Spivey, Kenneth Kreafle