Patents Represented by Attorney, Agent or Law Firm Grant Patent Services
  • Patent number: 6399097
    Abstract: An enteric coated pill for treating bacterial infections of the digestive tract, wherein the bacteria to be treated are selected from the group consisting of Listeria, Salmonella, E. coli, Campylobacter and combinations thereof, said pill comprising an effective amount of at least one lytic enzyme genetically coded by a bacteriophage specific for said bacteria of the digestive tract, whereby said enzyme has the ability to digest the cell wall of said bacteria; and a carrier for said enzyme.
    Type: Grant
    Filed: September 1, 2000
    Date of Patent: June 4, 2002
    Assignee: New Horizons Diagnostics Corporation
    Inventors: Vincent Fischetti, Lawrence Loomis
  • Patent number: 6399098
    Abstract: The present invention discloses a method for treating baterial dental caries caused by Streptococcus mutans, comprising administering a composition comprising an effective amount of at least one lytic enzyme produced by a bacteriophage specific for Streptococcus mutans, with the lytic enzyme having the ability to exclusively digest a cell wall of the Streptococcus mutans infecting all or part of a mouth or teeth, and a toothpaste for delivering the enzyme to the mouth and teeth.
    Type: Grant
    Filed: September 28, 2000
    Date of Patent: June 4, 2002
    Assignee: New Horizons Diagnostics Corp
    Inventors: Vincent Fischetti, Lawrence Loomis
  • Patent number: 6395504
    Abstract: A method for the use of a phage associated lysing enzyme for the detecting the presence and determining the quantity of bacteria present in or on a wide variety of substances is described. The total concentration of microbes is determined by adding or incorporating a phage associated lytic agent to a disposable test system device with the luminescent reagents luciferin and luciferase, and introducing the disposable test system into a luminometer that can read the luminescence. Other systems can be used with the lytic enzymes for the quantitative and qualitative determination for the presence of bacteria.
    Type: Grant
    Filed: September 1, 2000
    Date of Patent: May 28, 2002
    Assignee: New Horizons Diagnostics Corp.
    Inventor: David Trudil
  • Patent number: 6357183
    Abstract: The invention relates a water storage and storm water collection and detention system including at least one storage reservoir integrally attached to and extending along the edge of an extremity of a roof of a building structure; wherein the storage reservoir directly receives run-off from the roof. The system further includes at least one outlet, a supply line in communication with the outlet, an overflow outlet, and a float valve assembly connected to the supply line such that the reservoir communicates with a mechanism that allows for the water collected therein to be used with a water consumption apparatus or tap line on demand.
    Type: Grant
    Filed: April 16, 1997
    Date of Patent: March 19, 2002
    Inventor: Frank Smith
  • Patent number: 6326002
    Abstract: The present invention discloses a method for treating Streptococcal infections of the upper respiratory tract, comprising administering an effective amount of a lysin enzyme produced by group C Streptococcal bacteria infected with a C1 bacteriophage specific for the bacteria to a mouth, throat, or nasal passage of a mammal, the method providing a concentration of from about 100 to 500,000 active enzyme units per milliliter of fluid in the environment of said nasal or oral passages.
    Type: Grant
    Filed: September 28, 2000
    Date of Patent: December 4, 2001
    Assignee: New Horizons Diagnostics Corporation
    Inventors: Vincent Fischetti, Lawrence Loomis
  • Patent number: 6277399
    Abstract: A composition for treatment of bacterial infections of burns and wounds of the skin comprises an effective amount of at least one lytic enzyme produced by a bacteria infected with a bacteriophage specific for said bacteria, and a carrier for delivering said at least one lytic enzyme to the skin. The carrier may be, but is not limited to, a liquid solution applied to a bandage.
    Type: Grant
    Filed: September 28, 2000
    Date of Patent: August 21, 2001
    Assignee: New Horizon Diagnostics Corporation
    Inventors: Vincent Fischetti, Lawrence Loomis
  • Patent number: 6264945
    Abstract: The present invention discloses a method and composition for the treatment of bacterial infections by the parenteral introduction of at least one lytic enzyme produced by a bacteria infected with a bacteriophage specific for that bacteria and an appropriate carrier for delivering the lytic enzyme into a patient. The injection can be done intramuscularly, subcutaneously, or intravenously.
    Type: Grant
    Filed: January 14, 2000
    Date of Patent: July 24, 2001
    Inventors: Vincent A Fischetti, Lawrence Loomis
  • Patent number: 6254866
    Abstract: A method for treatment of bacterial infections of the digestive tract is disclosed which comprises administering a lytic enzyme specific for the infecting bacteria. The lytic enzyme is preferably in a carrier for delivering said lytic enzyme. The bacteria to be treated is selected from the group consisting of Listeria, Salmonella, E. coli, Campylobacter, and combinations thereof. The carrier for delivering at least one lytic enzyme to the digestive tract is selected from the group consisting of suppository enemas, syrups, or enteric coated pills.
    Type: Grant
    Filed: September 1, 2000
    Date of Patent: July 3, 2001
    Assignee: New Horizons Diagnostics Corporation
    Inventors: Vincent Fischetti, Lawrence Loomis
  • Patent number: 6248324
    Abstract: The present invention discloses a composition for dermatological infections by the use of a lytic enzyme in a carrier suitable for topical application to dermal tissues. The method for the treatment of dermatological infections comprises administering a composition comprising effective amount of a therapeutic agent, with the therapeutic agent comprising a lytic enzyme produced by infecting a bacteria with phage specific for that bacteria.
    Type: Grant
    Filed: September 28, 2000
    Date of Patent: June 19, 2001
    Inventors: Vincent Fischetti, Lawrence Loomis
  • Patent number: 6238661
    Abstract: Compositions and methods for the prophylactic and therapeutic treatment of bacterial infections are disclosed which comprise administering to an individual an effective amount of a composition comprising an effective amount of lytic enzyme and a carrier for delivering the lytic enzyme. This method and composition can be used for the treatment of upper respiratory infections, skin infections, wounds, burns, vaginal infections, eye infections, intestinal disorders and dental problems.
    Type: Grant
    Filed: April 18, 2000
    Date of Patent: May 29, 2001
    Assignee: New Horizons Diagnostics Corp.
    Inventors: Vincent Fischetti, Lawrence Loomis
  • Patent number: 6218808
    Abstract: An apparatus and method for fast battery charging are provided. A fast battery charger applies high charging current to a battery to minimize charging time. Micropeak detection of the battery voltage prevents overcharging of the battery cells, thereby preventing degradation of battery capacity over time. Noise reduction throughout the system as well as improved detection resolution allows for micropeak detection. A linear power supply eliminates switch noise. The sampling frequency is synchronized with the power supply, eliminating error due to power supply variation. Sleeping sampling is performed to overcome noise due to operation of the CPU. Improved measurement resolution is obtained via a 10-bit analog to digital converter. A subtraction technique maintains the high measurement resolution.
    Type: Grant
    Filed: March 24, 2000
    Date of Patent: April 17, 2001
    Assignee: Model Rectifier Corporation
    Inventor: Zhiping Lin
  • Patent number: 6206747
    Abstract: The invention discloses a colorful wind indicator toy, suitable for use by children, which will both educate and entertain them. The wind indicator toy comprises a tail section for catching the wind, a front section for indicating the direction of the wind, a tail mounting section for mounting the tail section, a joinder for joining the tail mounting section with the front section, and a pole upon which the assembly rotates.
    Type: Grant
    Filed: September 27, 1999
    Date of Patent: March 27, 2001
    Assignee: Go Fly A Kite
    Inventor: Mark Leslie Skwarek
  • Patent number: 6176836
    Abstract: The present invention discloses a biological sample collection kit which can be utilized to collect samples of biological origin for use in any recovery and identification method. The biological sample collection kit comprises a sterile device for collecting a sample, a collection and dispersing device for depositing and holding the sample, a device for transferring the sample, and a container for storing the sample to be tested. There may also be a labeling system for identifying the sample and for diluting the sample. The biological sample collection kit preferably contains an outer bag which holds, in a sterile environment, all of the items used in the testing procedures. Additionally, a container of collection fluid is preferably included in the sample collection kit.
    Type: Grant
    Filed: September 25, 1998
    Date of Patent: January 23, 2001
    Inventors: David Trudil, Lawrence Loomis
  • Patent number: 6146591
    Abstract: This device discloses a portable sequential contaminant detection system which can test samples for contaminants at predetermined timed intervals. The detection system has a motor to advance a matrix, a motor to raise and lower syringes holding liquefied samples of air to be tested, and a motor to raise and lower plungers within the syringes to draw up fluids or expel fluids into reservoir wells of the matrix to test air or other samples for contaminants. The system relies upon a "matrix" which will hold reagents with which the air samples will be mixed. The matrix is stepped to move into precise registration with the "read" module where the relative reflectance of each capture membrane reads statically by a fixed LED, silicon photodiode and amplifier associated with each channel.
    Type: Grant
    Filed: May 1, 1998
    Date of Patent: November 14, 2000
    Inventor: C David Miller
  • Patent number: 6123221
    Abstract: The present invention discloses a method for dispensing scented coupons in a way that activates the scents as they are removed from a coupon dispenser. Individual scented coupons have a folded end, with a light adhesive allowing for the On one side of As individual, folded scented coupons are removed from the dispenser box, The dispenser comprises walls defining a cavity adapted to receive the stack of sheets, a rectangular flat top wall having an opening through which the sheets may be individually dispensed, a flat bottom wall having approximately the same dimensions as the flat top wall, with the flat bottom wall being approximately parallel to the flat top wall, and resilient means to push the stack of said sheets to the opening in the top wall of the dispenser.
    Type: Grant
    Filed: August 6, 1998
    Date of Patent: September 26, 2000
    Assignee: Premium Promotions
    Inventor: Raymond Simpson
  • Patent number: 6084201
    Abstract: A method is provided for forming a molten oxide ceramic electrode for a plasma arc ignited between first and second electrodes within a plasma arc chamber, wherein the conductivity the oxide ceramic is a function of temperature alone. Following ignition of the plasma arc, a mixture is formed of a small quantity of molten oxide ceramic and a sufficiently high concentration of a volatile contaminant to render the mixture electrically conductive. The plasma arc is then transferred from one of the electrodes to the mixture. The temperature of the mixture is raised sufficiently to render the oxide ceramic electrically conductive. Finally, the volatile contaminant is progressively removed from the mixture so as to leave an electrode composed of substantially pure molten oxide ceramic.
    Type: Grant
    Filed: October 27, 1999
    Date of Patent: July 4, 2000
    Inventors: Ian Turner, Tony Addona, Richard Munz
  • Patent number: 6060680
    Abstract: A method is provided for forming a molten oxide ceramic electrode for a plasma arc ignited between first and second electrodes within a plasma arc chamber, wherein the conductivity the oxide ceramic is a function of temperature alone. Following ignition of the plasma arc, a mixture is formed of a small quantity of molten oxide ceramic and a sufficiently high concentration of a volatile contaminant to render the mixture electrically conductive. The plasma arc is then transferred from one of the electrodes to the mixture. The temperature of the mixture is raised sufficiently to render the oxide ceramic electrically conductive. Finally, the volatile contaminant is progressively removed from the mixture so as to leave an electrode composed of substantially pure molten oxide ceramic.
    Type: Grant
    Filed: August 6, 1998
    Date of Patent: May 9, 2000
    Inventors: Ian Turner, Tony Addona, Richard Munz
  • Patent number: 6056955
    Abstract: The present invention discloses a method and composition for the topical treatment of streptococcal infections by the use of a lysin enzyme blended with a carrier suitable for topical application to dermal tissues. The method for the treatment of dermatological streptococcal infections comprises administering a composition comprising effective amount of a therapeutic agent, with the therapeutic agent comprising a lysin enzyme produced by group C streptococcal bacteria infected with a C1 bacteriophage. The therapeutic agent can be in a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: September 14, 1999
    Date of Patent: May 2, 2000
    Inventors: Vincent Fischetti, Lawrence Loomis
  • Patent number: 6056868
    Abstract: The present invention discloses the doping of rare earth elements into porous silicon, resulting in enhancement of luminescence. The doping is an electro-chemical process using constant voltage bias across the two electrodes in which the anode is porous silicon and the cathode is platinum. The doping process involves a well-defined solution of electrolytes that controls the conductivity of the solution, and set values of constant voltages that selectively allow the desired rare earth elements being doped into porous silicon.
    Type: Grant
    Filed: May 22, 1998
    Date of Patent: May 2, 2000
    Inventors: Kok Wei Cheah, Wai Kwok Wong, Meng Lian Gong, Wan Han Zheng
  • Patent number: 6053570
    Abstract: The present invention is for a flexible device attachable to the underside of theater seats, allowing for the storage of personal items. The invention comprises an expandable storage structure, having a bottom section, a top section, a front section, a back section, and side sections, the side sections positioned between the top section and the bottom section and the front section and the back section, said expandable structure having an elasticized opening at the top section, and at least one strap attached to each of the two sides of the expandable structure with each distal end of said at least one strap having a closure mechanism, which is complementary with the other said closure mechanism, thereby allowing the distal ends of said straps to be removably connected.
    Type: Grant
    Filed: May 21, 1998
    Date of Patent: April 25, 2000
    Inventors: Cindy Jane Stern, Jesse Philip Stern