Abstract: Novel antimicrobial peptides from bovine and murine neutrophils are provided. The peptides, designated bovine granulocyte peptide A (BGP-A) and murine granulocyte peptide A (MGP-A) were purified to homogeneity from peripheral blood granulocytes. The amino acid and nucleotide sequence of BGP-A and MGP-A are also provided. A synthetic version of BGP-A and MGP-A is also provided. The purified BGP-A peptide is shown to have antimicrobial activity indistinguishable from that of natural BGP-A. Synthetic carboxamidated analogs of BGP-A (BGP-A-amide) and MGP-A (MGP-A-amide) are also provided.

Abstract: Systems and methods are described for a single self-aligned carbon nanofiber emitters within a dielectric well. A method, includes: providing a substrate; defining lithographically a catalyst particle, the catalyst particle coupled to the substrate; depositing a dielectric layer, the dielectric layer coupled to the substrate; depositing an extractor layer, the extractor layer coupled to the dielectric layer; forming an extractor aperture in the extractor layer; forming a dielectric well in the dielectric layer to uncover the catalyst particle; and then fabricating at a location of the catalyst particle and within the dielectric well a single self-aligned carbon containing tip i) having a base located substantially at the bottom of the dielectric well and ii) extending substantially away from the substrate using plasma enhanced chemical vapor deposition.

Abstract: The medium of a disk for CD-R is a pigmentation material so readout by a 650-nm laser diode (LD) is not possible. Since CD-R is becoming popular in the marketplace, there are demands for a DVD readout device that is capable of reading CD-R format disks. An integrated semiconductor laser element is created by forming a two-wavelength LD monolithically on a GaAs substrate, and that laser element emits a laser beam that is reflected by a 45° mirror incorporated in a flat package. If a three-part holographic element is used, and the light-receiving element and an amplification circuit are integrated on a silicon substrate, it is possible to implement a small, light-weight optical pickup with fewer components.

Abstract: The present invention provides a device for in-situ measurement and recording of various environmental parameters in a semiconductor fabrication process. The device includes sensors for detecting the parameters and converting them to sensor outputs and a data logger coupled to the sensors for receiving the sensor outputs and logging them in a file. The device may also include an analog to digital converter to convert the sensor outputs to digital data and a communication module to communicate the digital data with other devices. When applied to reticles used in a semiconductor fabrication process comprising a plurality of stages, the device may be used to monitor electrostatic field and electrostatic discharge activities on and around the reticle, convert the monitored parameters into data, and log the data along with a timestamp and an identification of each individual stage.

Abstract: An integrated element scale is provided that can replace an existing support structure within a piece of equipment to achieve a piece of equipment with the integrated scale. The integrated element scale may contain one or more load cells and be configured to replace a standard component used in the assembly of certain types of equipment. The integrated element may include a mechanism to align the load portion and support portion of the element with the load cell or load cells in between them. The integrated element may further include a mechanism for protecting the load cells from damage due to overload or under load as well as side impacts. When higher accuracy is required, the integrated element further may include a mechanism for decoupling the loads within each element from other load cells within the same element or other elements so that horizontal loading between the deflecting load cells does not occur.

Abstract: The present invention is to provide an integrated circuit, a macrocell and method of layout for an integrated circuit capable of reduction in chip area using an area in macrocells. The macrocell according to the invention has concavity-shaped, and an integration circuit of the present invention includes a concave macrocell. The layout method according to this invention comprises, inputting a target macrocell, searching for blank areas in the macrocell, replacing the macrocell with a macrocell that the blank area searched is removed; and layout the integrated circuit using the macrocell that the blank area searched is removed. A macrocell excluding the non-circuit areas be used efficiently so that reduction in chip area can be realized by using the integrated circuit including the macrocell according to this invention.

Abstract: A virtual distributed optical crossbar local area network configuration where the central switch or network controller has been eliminated. A virtual distributed optical crossbar allows a network to be fully scalable as the number of users increases. The virtual distributed optical crossbar is fully non-blocking and is reconfigurable. In addition the virtual distributed optical crossbar has zero latency across the network, employs vertical cavity surface emitting laser technology and smart pixel technology in conjunction with a resonant cavity enhanced (RCE) waveguide grating coupler (WGC). Optical signals are transmitted through fiber optic and/or waveguide or freespace interconnects implementing the switching functions. The waveguide technology provides the enabling mechanism to achieve a zero latency, fully non-blocking, performance. Address decoding functions between processors is divided, leaving only the true distance interconnect implemented by optical means.

Abstract: A dielectric-loaded antenna having a plurality of radiating elements and a loop element plated on the surface of a cylindrical ceramic core has balanced and single-ended modes of resonance which are coupled together so as to define an operating frequency band. The two modes of resonance are associated with different respective radio frequency current patterns in the radiating elements, and the input reactance component of the load represented by the antenna at its feedpoint is substantially zero within the operating frequency band only when the corresponding input resistance component is finite and substantially non-zero.

Abstract: The invention described herein comprises a method of treating a subject having a disorder characterized by the presence of one or more tumors comprising inserting a miniaturized concentrated neutron emitting source into said tumor(s) for a time sufficient to irradiate the cells of the tumor(s). The invention method can be employed in the treatment of both malignant and non-malignant tumors and is especially useful in the treatment of malignant tumors found in the brain, prostate, and other internal organs. A preferred neutron source is californium-252. The majority of the tumor can be surgically removed prior to insertion of the neutron emitting source. In a further embodiment of the invention, a neutron capture compound can be localized to the cells of the tumor prior to insertion of the miniaturized neutron emitting source in order to augment the effects of neutron therapy.

Abstract: The present invention features biarsenical molecules. Target sequences that specifically react with the biarsenical molecules are also included. The present invention also features kits that include biarsenical molecules and target sequences. Tetraarsenical molecules are also featured in the invention.

Abstract: A system and method for object inspection that includes an image recognition program stored on a tangible medium for classifying and subclassifying regions of interest on an image. The image recognition program can be used in an image inspection system to determine defects on objects such as printed wiring assemblies. The image recognition program is executable to collect raw image data, segment out rectangular regions of interest that can be component sites defined by CAD data, preprocess each region of interest by scaling, gain and offset correction, and gamma correction, generating a set of image spaces for each region of interest using a set of spatial image transforms, generating features on the image spaces, scoring the features, comparing the feature scores to a knowledge base of feature scores to make a class determination for the features, generating a presence/absence decision confidence for the features, calculating a class determination and decision confidence for each region of interest.

Abstract: This invention provides a novel wavelength-separating-routing (WSR) apparatus that uses a diffraction grating to separate a multi-wavelength optical signal by wavelength into multiple spectral channels, which are then focused onto an array of corresponding channel micromirrors. The channel micromirrors are individually controllable and continuously pivotable to reflect the spectral channels into selected output ports. As such, the inventive WSR apparatus is capable of routing the spectral channels on a channel-by-channel basis and coupling any spectral channel into any one of the output ports. The WSR apparatus of the present invention may be further equipped with servo-control and spectral power-management capabilities, thereby maintaining the coupling efficiencies of the spectral channels into the output ports at desired values.

Abstract: The present invention provides a system and method for optimizing a cache that substantially eliminates reduces the disadvantages of previously developed cache management systems. More particularly, embodiments of the present invention provide a system of optimizing a cache by polling cached assets with a frequency dependent of the relative activity of a cached asset. An embodiment of the method of the system includes the steps of: (i) polling a cached asset according to a first schedule to determine if the cached asset has been active within a first predefined period of time; (ii) if the cached asset has not been active, polling the cached asset according to a second schedule to determine if the cached asset has been inactive for at least a second predefined period of time; (iii) demoting the cached asset to less active status; and (iv) if the cached asset has been inactive for at least within the second predefined period of time, demoting the cached asset to inactive status.

Abstract: Methods for identifying a hyaluronidase 2 (HYAL2) specific inhibitor, which selectively inhibits HYAL2 activity, but does not substantially affect the activity of non-inflammatory hyaluronidases, are provided. Also provided are HYAL2 specific inhibitors obtained using such a method. In addition, methods for ameliorating an inflammatory disorder or vasculitis condition by specifically inhibiting HYAL2 is provided.

Abstract: The mass flow controller of the present invention includes a sensor. This sensor is used to detect a mass flow within a gas line. Additionally, this sensor provides an output to an electronic control system coupled to the sensor. The electronic control system will determine an expected mass flow based on the output of the sensor. The electronic control system will adjust a control valve with a control signal to regulate a first gas flow through the control valve.

Abstract: The present invention provides antibodies that bind to the growth differentiation factor-7.

Abstract: The invention dynamically compensates for differences in data rates. In one embodiment, the status of an input buffer is monitored and used to change the number of oversamples within a frame. In another embodiment, a high frequency clock in the system is used to stall the codec for one clock. In both ways, distortion due to differences in data rates is reduced.

Abstract: The present invention provides a system and method for eliminating hidden surfaces in 3D graphics that improves rendering performance by decreasing the size of the data stored to or retrieved from the depth buffer when the distance from the camera to the pixel on the surface of the primitive is further than the threshold distance. The threshold distance from the camera is defined such that for such pixels the precision of a linear or quazi-linear depth buffer with a decreased data size is the same as or higher than the precision of a non-linear depth buffer with an original data size. The invention improves the usefulness of linear and quasi-linear depth buffers for 3D applications optimized for non-linear depth buffers. The present invention additionally affords a method for selecting the size of data to be read from the depth buffer before new depth values are computed for the same pixels.