Patents Represented by Attorney, Agent or Law Firm Hamilton, Brook, Smith & Reynolds
  • Patent number: 8219353
    Abstract: A measurement apparatus calibrated to measure an absolute diameter of a part in a shop floor environment. The measurement apparatus includes a calibration that includes compensation factors for thermal expansion, shifting of measurement parts (arm, support tower, and related laser), and variances of these parts. The resulting measurements report an absolute diameter of a part to a higher degree of accuracy than previously possible. Also, the calculated compensation factor eliminate the need for an isolated, climate-controlled measurement room.
    Type: Grant
    Filed: January 28, 2010
    Date of Patent: July 10, 2012
    Assignee: Axiam, Inc.
    Inventors: Robert M. Lee, Robert E. Parsons
  • Patent number: 8218386
    Abstract: A dynamic random access memory (DRAM) having pairs of bitlines, each pair being connected to a first bit line sense amplifier, wordlines crossing the bitlines pairs forming an array, charge storage cells connected to the bitlines, each having an enable input connected to a wordline, the bit line sense amplifiers being connected in a two dimensional array, pairs of primary databuses being connected through first access transistors to plural corresponding bit line sense amplifiers in each row of the array, apparatus for enabling columns of the first access transistors, databus sense amplifiers each connected to a corresponding data bus pair, a secondary databus, the secondary databus being connected through second access transistors to the databus sense amplifiers, and apparatus for enabling the second access transistors, whereby each the primary databus pair may be shared by plural sense amplifiers in a corresponding row of the array and the secondary databus may be shared by plural primary databus pairs.
    Type: Grant
    Filed: November 23, 2010
    Date of Patent: July 10, 2012
    Assignee: MOSAID Technologies Incorporated
    Inventor: Richard C. Foss
  • Patent number: 8215446
    Abstract: A region of air is manipulated to reflect, absorb, or redirect sound energy to prevent the sound energy from reaching a listener separated from the sound source by the region of air. The region of air may be manipulated by directing ultrasonic sound waves with a sound pressure level of at least 140 decibels at the region of air.
    Type: Grant
    Filed: June 25, 2010
    Date of Patent: July 10, 2012
    Inventor: F. Joseph Pompei
  • Patent number: 8215479
    Abstract: A display for display articles such as coins or medallions including a generally planar plastic sheet having one or more retaining structures for capturing one or more display articles. The plastic sheet has opposite first and second generally planar sides. A first paper board sheet is bonded to the first side of the plastic sheet, and a second paper board sheet is bonded to the second side of the plastic sheet. The plastic sheet can have the same dimensions of at least one of the paper board sheets.
    Type: Grant
    Filed: August 14, 2009
    Date of Patent: July 10, 2012
    Assignee: Unicover Corporation
    Inventors: James A. Willms, Eric Delaplaine, Cheryl Mefford
  • Patent number: 8216797
    Abstract: The invention described herein provides methods for the detection of target particles, such as pathogens, soluble antigens, nucleic acids, toxins, chemicals, plant pathogens, blood borne pathogens, bacteria, viruses and the like. Also described is an emittor cell comprising a receptor, wherein the receptor can be an antibody or an Fc receptor, and an emittor molecule for the detection of a target particle in a sample wherein the target particle to be detected is bound by one or more receptors on the emittor cell. Also provided are optoelectronic sensor devices for detecting a target particle in a sample, including in a plurality of samples.
    Type: Grant
    Filed: November 30, 2006
    Date of Patent: July 10, 2012
    Assignee: Massachusetts Institute of Technology
    Inventors: Eric Schwoebel, James Harper, Martha S. Petrovick, Frances Nargi, Mark Hollis, Bernadette Johnson, Joseph Lacirignola, Richard Mathews, Kristine Hogan, Trina Vian, Allan Heff, Mark Hennessy, Songeeta Palchaudhuri, Todd Rider
  • Patent number: 8213240
    Abstract: In a nonvolatile memory, less than a full block maybe erased as one or more pages. A select voltage is applied through pass transistors to each of plural selected wordlines and an unselect voltage is applied through pass transistor to each of plural unselected wordlines of a selected block. A substrate voltage is applied to the substrate of the selected block. A common select voltage may be applied to each selected wordline and the common unselect voltage may be applied to each unselected wordline. Select and unselect voltages may be applied to any of the wordlines of a select block. A page erase verify operation may be applied to a block having plural erased pages and plural nonerased pages.
    Type: Grant
    Filed: June 27, 2011
    Date of Patent: July 3, 2012
    Assignee: Mosaid Technologies Incorporated
    Inventor: Jin-Ki Kim
  • Patent number: 8213561
    Abstract: A delay locked loop operates over a wide range of frequencies and has high accuracy, small silicon area usage, low power consumption and a short lock time. The DLL combines an analog domain and a digital domain. The digital domain is responsible for initial lock and operational point stability and is frozen after the lock is reached. The analog domain is responsible for normal operation after lock is reached and provides high accuracy using smaller silicon area and low power.
    Type: Grant
    Filed: July 19, 2011
    Date of Patent: July 3, 2012
    Assignee: Mosaid Technologies Incorporated
    Inventors: Peter Vlasenko, Dieter Haerle
  • Patent number: 8214235
    Abstract: A method of enterprise risk management includes defining a hierarchical organizational model to represent an enterprise. The model has a master level and one or more levels subordinate to the master level. The master level has plural materiality grades and plural probability grades, each subordinate level including one or more entities have a reporting relationship to one of the entities in the preceding level, each entity having plural materiality grades. Risk information is collected which includes risk items, each associated with a particular entity in the hierarchical organizational model and having a materiality measure and a probability measure. Selected portions of the collected risk information is output in an output view that for each selected risk item relates the probability measure to the plural probability grades and the materiality measure to either the plural master level materiality grades or the plural entity level materiality grades depending on a selected level.
    Type: Grant
    Filed: June 20, 2006
    Date of Patent: July 3, 2012
    Assignees: Core Systems Group, LLC
    Inventors: Andrew M. Tait, Daniel E. Garlewicz
  • Patent number: 8214228
    Abstract: A substance abuse surveillance system comprising a source of respondent responses to a self-administered virtual interview and a data collector coupled to receive from the source multiple respondent responses and analyzing the same in near real-time to form current substance abuse data, the data collector allowing access to the current substance abuse data by third parties. The data collector is coupled to the source in a manner enabling delay-free, continuous feed of the respondent responses.
    Type: Grant
    Filed: December 27, 2006
    Date of Patent: July 3, 2012
    Assignee: Inflexxion, Inc.
    Inventors: Stephen F. Butler, Simon H. Budman, Nathaniel Paul Katz, Albert J. Villapiano
  • Patent number: 8213340
    Abstract: A telecommunication network includes a communication ring having a plurality of nodes. The communication ring includes a plurality of links wherein each link interconnects one node to another node. Each node includes one or more network elements. Management functions for the nodes, the communication ring, the links, and the network elements are provided by a manager. The manager can discover and define the nodes, the links, and the communication ring and establish more than one network element at a node. The manager provides a coherent view of the telecommunication network despite a node being supported by more than one network element.
    Type: Grant
    Filed: August 15, 2005
    Date of Patent: July 3, 2012
    Assignee: Tellabs Operations, Inc.
    Inventors: Barry Glicklich, David Allabaugh, Philippe Wilson
  • Patent number: 8214356
    Abstract: A database management system implemented in a cloud computing environment. Operational nodes are assigned as groups of controller-nodes, compute-nodes or storage-nodes. Queries specify one or more tables for an associated database operation, with each table being assigned to respective storage nodegroup(s). The number of nodes executing a given query may change, by (a) changing the compute-nodes associated with a connection, or (b) adding or removing nodes associated with a connection; and/or distributing data to a storage nodegroup based on a Distribution Method which may be either data dependent or data independent. A controller node further executes a Dynamic Query Planner (DQP) process that develops a query plan.
    Type: Grant
    Filed: March 5, 2012
    Date of Patent: July 3, 2012
    Assignee: ParElastic Corporation
    Inventor: Mrithyunjaya Annapragada
  • Patent number: 8212207
    Abstract: The invention uses liquid chromatography-mass spectrometry to verify the presence or absence of the extractables introduced into a biopharmaceutical product during manufacture, filtration or storage at above a certain concentration. The method disclosed herein can be used to detect the presence of extractables in the actual biopharmaceutical product rather than a surrogate solvent system. Detection of the extractables in the actual drug product provides an accurate description of the leachables profile likely to be introduced to the human or animal patient. In one embodiment, the extractable are introduced by filtration of the bio-pharmaceutical product.
    Type: Grant
    Filed: August 22, 2008
    Date of Patent: July 3, 2012
    Assignee: EMD Millipore Corporation
    Inventors: Tongbo Jiang, Cheryl Follo, Maurice G. Phelan
  • Patent number: 8210571
    Abstract: A book cover (10) having a spine (26) and end covers (32) on either side of the spine (26) wherein the spine and end covers (32) are all formed from a single, folded blank (12) and the end covers (32) comprise at least two adhered layers of the folded blank.
    Type: Grant
    Filed: March 3, 2006
    Date of Patent: July 3, 2012
    Assignee: Roylebind Pty Ltd.
    Inventor: Clifford Royle
  • Patent number: 8206910
    Abstract: The invention is directed to methods of diagnosing breast cancer, susceptibility to breast cancer, nodal metastasis of a breast cancer and screening for breast cancer in an individual in need thereof comprising detecting the presence of a loss of heterozygosity/allelic imbalance (LOH/AI) at one or more specific loci (markers) in the genome of the individual, wherein the presence of the LOH/AI at the one or more specific loci in the genome of the individual is indicative of a diagnosis of breast cancer in the individual.
    Type: Grant
    Filed: December 8, 2009
    Date of Patent: June 26, 2012
    Assignee: The Cleveland Clinic Foundation
    Inventor: Charis Eng
  • Patent number: 8207315
    Abstract: This invention provides isolated nucleic acid and amino acid sequences encoding VG5Q, a novel angiogenic growth factor protein with pro-angiogenic activity, a forkhead-associated domain, a G-patch domain; characteristic subcellular localization in an in vitro Matrigel model of angiogenesis: towards the cell periphery in early stages of tubulogenesis, between cells in newly formed endothelial tubes, and no nuclear staining after 24 hours; is expressed in endothelial cells; is secreted during angiogenesis; and interacts with TWEAK. The invention also provides for expression vectors containing nucleic acid sequences encoding VG5Q protein, and host cells containing one or more expression vectors for the recombinant expression of VG5Q. The invention also provides for methods of using VG5Q for the diagnosis and treatment of angiogenesis-mediated diseases or disorders.
    Type: Grant
    Filed: August 20, 2004
    Date of Patent: June 26, 2012
    Assignee: The Cleveland Clinic Foundation
    Inventors: Qing K. Wang, Xiao-Li Tian, Rajkumar Kadaba
  • Patent number: 8209515
    Abstract: The systems and methods described herein include among other things, systems for providing a block level data storage service. More particularly, the systems and methods of the invention provide a block level data storage service that provides differentiated pools of storage on a single storage device. To this end, the systems and methods described herein leverage the different performance characteristics across the logical block name (LBN) space of the storage device (or devices). These different performance characteristics may be exploited to support two or more classes of storage on a single device.
    Type: Grant
    Filed: May 2, 2011
    Date of Patent: June 26, 2012
    Assignee: Dell Products LP
    Inventor: Eric R. Schott
  • Patent number: 8206717
    Abstract: The invention provides the antibody 2C3 and target binding members based on 2C3 which binds interleukin-25. These are useful in therapy, e.g. the treatment of asthma.
    Type: Grant
    Filed: April 17, 2008
    Date of Patent: June 26, 2012
    Assignee: Medical Research Council
    Inventors: Andrew Neil James McKenzie, Sarah Ballantyne
  • Patent number: 8206331
    Abstract: An ultrafiltration device adapted to be worn on a portion of the body of a patient includes a blood inlet tube leading from a first blood vessel, a blood pump, an anticoagulant reservoir for infusing anticoagulants into the blood, a blood filter including a substrate through which the blood is circulated and filtered, a fluid bag for storing the excess fluid and a blood outlet tube leading to a second blood vessel.
    Type: Grant
    Filed: December 11, 2009
    Date of Patent: June 26, 2012
    Assignee: Fresenius Medical Care Holdings, Inc.
    Inventors: Victor Gura, Edmond Rambod
  • Patent number: 8206922
    Abstract: Methods are described for screening a subject for risk of Charcot-Marie-Tooth Disease Type 2A or for diagnosing Charcot-Marie-Tooth disease or a predisposition for developing Charcot-Marie-Tooth disease in a subject, by detecting the presence or absence of a mutation in the mitofusin gene in a biological sample collected from the subject. Methods are also described for detecting the presence of a genetic polymorphism associated with Charcot-Marie-Tooth Disease Type 2A in a sample of patient nucleic acid, by amplifying a mitofusin gene sequence in the patient nucleic acid to produce an amplification product; and identifying the presence of a Charcot-Marie-Tooth Disease Type 2A associated polymorphism in the amplification product.
    Type: Grant
    Filed: March 25, 2010
    Date of Patent: June 26, 2012
    Assignee: Duke University
    Inventors: Jeffery M. Vance, Stephan Zuchner, Margaret A. Pericak-Vance
  • Patent number: 8206921
    Abstract: This invention relates to the use of genetic probes for detection of the presence of the SCCmec cassette in Staphylococcus aureus. In one aspect, the invention allows specific detection and identification of methicillin-resistant S. aureus (MRSA) in a clinical sample without interference from the presence of other non-S. aureus methicillin-resistant staphylococci. In another aspect, the invention allows specific detection and identification of methicillin-resistant coagulase negative staphylococci (MRCNS) originating from a clinical sample without interference from the presence of methicillin-resistant S. aureus.
    Type: Grant
    Filed: November 17, 2009
    Date of Patent: June 26, 2012
    Assignee: AdvanDx, Inc.
    Inventors: Henrik Stender, Anne Karin Ildor Rasmussen, Mark J. Fiandaca