Abstract: A compound which inhibits both of EGF receptor tyrosine kinase and HER2 tyrosine kinase is provided. A compound represented by the general formula (I): wherein RX is a group represented by the formula: wherein R1 is a hydrogen atom, optionally substituted alkyl, etc.; Z is —O—, —N(R10)—, etc.; R10 is a hydrogen atom, alkyl, etc.; R2 is a hydrogen atom, optionally substituted alkyl, etc.; R18 is a hydrogen atom, optionally substituted alkyl, etc.; R19 is optionally substituted alkyl, etc.; W1 is an optionally substituted non-aromatic nitrogen-containing group; R17 is a hydrogen atom, optionally substituted alkyl, etc.; R3 and R4 are independently a hydrogen atom, optionally substituted alkyl, etc.; X is —O—, —S—, or —N(R12)—, etc.; R12 is a hydrogen atom, alkyl, etc.; and A is phenyl optionally having a substituent, etc., its pharmaceutically acceptable salt, or a solvate thereof.
Abstract: A multi-directional sound emission system comprises a speaker body and sound emission devices coupled to both ends of the speaker body. The sound emission devices each include a sound emission means for directionally emitting sound towards multiple directions. The sound emission means includes a plurality of hollow mechanical sound conducting elements. Each hollow mechanical sound conducting element has an inner opening end and an exterior opening end opposite to the inner opening end. The exterior opening ends of the sound conducting elements are directed towards desired multiple directions, respectively. The sound emission means is configured for receiving sound signals from the speaker body and emitting sound along the desired multiple directions through the sound conducting elements.
Abstract: A grapple attachment for use with a drill pipe having a diameter, that may include first and second gripping members disposed on a rigid lateral member tiltable up to 40 degrees from the horizontal and preferably continuously rotatable, wherein each of the first and second gripping members has a first and second claw and a bracket having a concave contact surface, each claw having a concave gripping surface, wherein the surface of the bracket and the gripping surfaces of the first and second claws come in contact with the drill pipe when the gripping member is in the closed position.
Abstract: Method for applying a reinforced composite material, such as a fibre reinforced polymer (FRP) laminate or a steel reinforced polymer (SRP) laminate or a steel reinforced grout (SRG) composite, to a structural member. The method comprises the steps of: applying a curable adhesive to a surface of the structural member and/or a surface of the reinforced composite material, and bringing said surfaces into contact. A pre-stressing force, Pmax, is directly or indirectly applied to the reinforced composite material. The pre-stressing force, Pmax, to which a treatment length, LT, of the reinforced composite material is subjected is then decreased so that the reinforced composite material along the treatment length, LT, will be less pre-stressed than the reinforced composite material adjacent to the treatment length, LT, when the adhesive has cured.
June 27, 2008
Date of Patent:
January 8, 2013
Mohammad Al-Emrani, Robert Kliger, Reza Haghani
Abstract: A computing architecture and network topology definition module which provide the ability to tailor a hardware network topology to differing needs. Computing resources are interconnected into a network implementation using an optical wavelength division multiplexing (WDM) star/coupler approach. The overall topology for the network is defined by the network topology definition module, which is a removable device that defines the network topology and communication connectivity between the computing resources. Replacement of the network topology definition module with a different network topology definition module changes the network topology and communication connectivity, allowing the computing resources to be tailored to particular needs.
Abstract: A multi-directional sound emission means and a system having same are disclosed. The system comprises a speaker body and sound emission devices coupled to both ends of the speaker body. The sound emission devices each include a sound emission means for directionally emitting sound towards multiple directions. The sound emission means includes a base, a loudspeaker disposed on the base, and a plurality of hollow mechanical sound conducting elements. The loudspeaker has an opening where the sound is emitted. Each hollow mechanical sound conducting element has an inner opening end and an exterior opening end opposite to the inner opening end. The exterior opening ends are directed towards desired multiple directions, respectively. The inner opening ends are in sound communication with the opening of the loudspeaker such that sound from the loudspeaker is emitted along the desired multiple directions through the sound conducting elements.
Abstract: A multi-stage receiver comprises an input stage, an intermediate stage, and an output stage. The input stage is configured to provide a first signal and a second signal. The intermediate stage is coupled to the input stage and comprises a first amplifying circuit and a second amplifying circuit. Positive and negative input terminals of the first amplifying circuit receive the first signal and the second signal, respectively. Positive and negative input terminals of the second amplifying circuit receive the second signal and the first signal, respectively. The output stage is coupled to the intermediate stage and configured to generate low-skewed differential signals according to output signals of the intermediate stage.
Abstract: A safe area voltage and current interface is provided that includes an antenna and mode selection unit, an antenna tuner unit and an interface unit. The antenna and mode selection unit determines a frequency mode and an antenna mode for an output signal. The antenna tuner unit is directly connected to the antenna and mode selection unit and is configured to tune the output signal based on the frequency mode and the antenna mode determined by the antenna and mode selection unit. The interface unit is directly connected to the antenna tuner unit and is configured to ensure that a current and voltage level of the output signal does not exceed an intrinsically safe current and voltage level, while maintaining the peak current level of the output signal to a level sufficient to drive an electronic component disposed in an unsafe environment.
Abstract: A plurality of power supply circuits Z1? are provided according to a load capacity. The power supply circuits Z1? have sides connected in parallel on the side of a direct current input Vi and have sides connected in series on the sides of alternating current outputs Ao. A rectifying circuit DC1 is connected via a resonance circuit Z2 across a combined output of the serially connected sides of the power supply circuits Z1? on the sides of the alternating current outputs Ao. Switching frequencies are simultaneously controlled by a single control signal outputted from a control circuit S1 based on a direct current output voltage detected from the rectifying circuit DC1 through a detection resistor R5.
Abstract: Systems and processes for compressing, translating and storing solid-state model data for a plurality of parts that form a solid-state model is provided. Compressing, translating and storing solid-state model data includes extracting the solid-state model data. Compressing, translating and storing solid-state model data also includes translating the sorted solid-state model data into one or more assembly components, a plurality of part components and a plurality of surface components. The process further requires storing each of the one or more assembly components, each of the plurality of part components and each of the plurality of surface components into a single file.
Abstract: An infant swaddle blanket that includes a torso wrap section with wings and a leg pouch for the infant's legs. The torso wrap section is designed to wrap around the infant's torso for swaddling. The swaddle includes various hook and loop fasteners which facilitates swaddling and makes the swaddle easier to use, as well as making the swaddle safer to use by providing a more secure, adjustable fit. External hold-down straps augment hook and loop closures on the wings. The leg pouch permits the infant's diaper to be changed without unwrapping the torso wrap section, thereby facilitating diaper changes.
Abstract: In a recording medium including stacked recording layers, management data requiring reliability is recorded in the recording layer far from the surface of the recording medium and data bodies are recorded in the recording layer close to the surface of the recording medium. Thus a data file can be read even if defects such as fingerprints and scratches occur on the surface of the recording medium.
Abstract: A rotor (21) is an interior permanent magnet rotor formed of a rotor core (24) in which a plurality of permanent magnets (25) are embedded at predetermined intervals. First protruding portions (26) and second protruding portions (27) are formed on an outer peripheral face of the rotor, the first protruding portions (26) each opposing the vicinity of a central portion of each of the permanent magnets and having a substantially arc-shaped cross section protruding outward and the second protruding portions (27) each opposing the vicinity of an end portion of each of the permanent magnets and protruding outward. One first protruding portion and two second protruding portions correspond to one permanent magnet. The formation of the first and second protruding portions as described above on the outer peripheral face of the rotor makes it possible to sufficiently reduce the torque ripple and the noise caused by the distortion of air-gap magnetic flux distribution.
Abstract: An inexpensive biosensor is provided that can realize an electrochemical analysis and perform measurement with high accuracy or convenience. The biosensor is an immunological sensor that enables measurement anywhere at anytime by anyone while keeping convenience. The biosensor includes: an electrode sensor unit 4 in which an electric conductive layer 2 is provided on an electrode-unit forming substrate 1 having an insulating property and an electrode portion 3 for detecting an electrochemical signal is formed on the electrode-unit forming substrate 1; and a chromatographic sensor unit 10 in which an extended layer 7 including a porous film for extending a specimen solution is provided on an extended-portion forming substrate 6, wherein the electrode sensor unit 4 and the chromatographic sensor unit 10 are stacked with the extended-portion forming substrate 6 interposed between the electrode sensor unit 4 and the chromatographic sensor unit 10.
Abstract: The present invention discloses a polarization-maintaining reflector arrangement comprising a reflector group including at least one polarizing reflector and at least one compensating reflector, wherein the incident plane for the polarizing reflectors is perpendicular to the incident plane for the compensating reflectors, and the product of s-wave reflectance of all the polarizing reflectors and p-wave reflectance of all the compensating reflectors is equal to the product of s-wave reflectance of all the compensating reflectors and p-wave reflectance of all the polarizing reflectors. One or more reflector groups can be used in the light path. The invention can conveniently and effectively eliminate the polarization caused by reflection.
Abstract: Multi-functional container for electric and/or electronic apparatuses comprising a front face, with a first compartment, to house at least one component (16) of the electric and/or electronic apparatus. The container comprises an opposite rear face having first attachment means (34) suitable to attach the container on guide means of a standardized type (36) in a first installation configuration. The multi-functional container also comprises second attachment means (42), suitable to attach the container in a second installation configuration inserted, at least partly, in a housing seating with the front face disposed toward the inside of the housing seating, and a second compartment, suitable to house the component (16) and disposed on the rear face.
Abstract: Systems and techniques for regulating the security of information flow can include multiple information receiving/transmitting domains where a device failure in one or more domains would not comprise the security of the systems. The systems and techniques may be implemented using a multi-domain checking approach in which the respective device operation status in each receiving/transmitting domain is independently monitored. The systems and techniques can advantageously prevent sensitive information from being inadvertently transferred to an untrusted or unauthorized entity.
Abstract: The invention discloses an Ochrobactrum sp. for degrading TBBPA and its application in environmental remediation. An Ochrobactrum sp. for degrading TBBPA was isolated from the sludge in a high risk area of electronic waste in the invention. The strain is named as Ochrobactrum sp. T, which has been deposited in China Center for Type Culture Collection (CCTCC) on Oct. 28, 2009 with an accession number of CCTCC M209246. Ochrobactrum sp. T obtained in the invention has high degradation capability to TBBPA in environment. The degradation efficiency of the strain achieves 96.2%. The strain could be applied to degrading TBBPA in environmental remediation.
December 30, 2009
Date of Patent:
January 1, 2013
Guangzhou Institute of Geochemistry, Chinese Academy of Science