Abstract: The invention covers the combination of utilizing the selectivity of an adsorbent to remove species from a liquid containing mixtures of ions and then subjecting the loaded resin to a chromatographic displacement utilizing the most selectively adsorbed species to displace the undesired co-adsorbing impurities. The technique can be used even when the most selectively adsorbed species is present as a minor constituent in the feed solution.
Abstract: (Problems) To provide a therapeutic agent for infections comprising granulysin as an active ingredient which has little side effect and no cytotoxicity and to which bacteria can hardly acquire resistance, and a treatment method using the same. (Means for Solving Problems) The present invention provides a therapeutic agent for infections comprising as active ingredient: 15K granulysin, a combination of 15K granulysin and 15K granulysin in vivo expression vector, a combination of 15K granulysin and at least one interleukin selected from IL-6, IL-23 or IL-27, a combination of 15K granulysin in vivo expression vector and at least one interleukin selected from IL-6, IL-23 or IL-27, or a combination of 15K granulysin in vivo expression vector and HSP65DNA and IL-12DNA in vivo expression vector, which enhances killing effects on bacteria and has less side effect, and to which bacteria can hardly acquire resistance, and a treatment method using the same.
Type:
Grant
Filed:
April 24, 2009
Date of Patent:
October 16, 2012
Assignees:
National Hospital Organization Kinki-chuo Chest Medical center, AZBIO Corporation
Abstract: The support system and method enables exact and preferably machine assisted manual location and height placement of a vacuum operated hold down with rigid pre-set support on a conventional working table. A height adjustable jack screw support with angularly flexible hold down enables a holding support engaging the bottom of a work piece even where a lower surface of the work piece has an irregular shape due to the ability of the upper cup support to passively tilt to engage the work piece.