Patents Represented by Attorney Harry H. Kline
  • Patent number: 4289903
    Abstract: There are provided certain p-phenylalkoxy phenylurea and thiourea compounds useful for the control of undesirable plants in the presence of agronomic crops and to methods for the preparation of said phenylalkoxy phenylurea and thiourea compounds.
    Type: Grant
    Filed: June 25, 1979
    Date of Patent: September 15, 1981
    Assignee: American Cyanamid Company
    Inventors: David M. Spatz, Barrington Cross
  • Patent number: 4284771
    Abstract: There is provided a novel, economical process for preparing melamine from cyanogen and ammonia in the vapor phase and in the absence of dehydrogenation catalysts.
    Type: Grant
    Filed: September 8, 1980
    Date of Patent: August 18, 1981
    Assignee: American Cyanamid Company
    Inventors: Hsuan L. Tien, Kenneth E. Olson
  • Patent number: 4267191
    Abstract: There are provided novel furfuryl thiourea compounds which are effective for enhancing the growth rate of meat-producing animals and for improving the efficiency of feed utilization thereby, when administered to said animals in effective amounts in or with their feed or by parenteral administration.
    Type: Grant
    Filed: May 21, 1980
    Date of Patent: May 12, 1981
    Assignee: American Cyanamid Company
    Inventors: Pamela K. Baker, Goro Asato, John Dusza
  • Patent number: 4262122
    Abstract: There is provided a novel process for preparing 5,5-dimethyl-2-hydrazino-1,4,5,6-tetrahydropyrimidine hydrohalide by causing neopentyldiamine to react with a guanidine hydrohalide and followed by treating the so-formed reaction product with hydrazine to yield the desired tetrahydropyrimidine hydrohalide. Alternatively, neopentyldiamine, guanidine hydrohalide and hydrazine can be admixed and reacted to yield the desired tetrahydropyrimidine hydrohalide.
    Type: Grant
    Filed: February 19, 1980
    Date of Patent: April 14, 1981
    Assignee: American Cyanamid Company
    Inventors: Robert G. Lees, Andrew S. Tomcufcik
  • Patent number: 4254268
    Abstract: There is provided an oxidation process using potassium permanganate as oxidizing agent, for the preparation of certain animal growth promoters, namely, N-(4,5,6,7-tetrahydro-7-oxobenzo[b]thien-4-yl)amides, 4,5,6,7-tetrahydro-7-oxobenzo[b]-thien-4-ylureas, N-(1,2,3,4-tetrahydro-4-oxo-1-naphthyl)amides and 1,2,3,4-tetrahydro-4-oxo-1-naphthylureas, said process affording such compounds in markedly improved yields, and being readily suitable for scale-up.
    Type: Grant
    Filed: June 22, 1978
    Date of Patent: March 3, 1981
    Assignee: American Cyanamid Company
    Inventor: Henry L. Strong
  • Patent number: 4245103
    Abstract: Processes for reacting arylvinyl oxides and alkoxyethylamines to provide novel N-substituted alkoxyethylamines; processes for reacting the novel N-substituted amines with nitriles to provide novel amidoamines; processes for preparing novel diamines from the amidoamines, together with the novel nitrogen-containing products so produced, such products being useful for the preparation of various imidazothiazoles including tetramisole.
    Type: Grant
    Filed: August 2, 1979
    Date of Patent: January 13, 1981
    Assignee: American Cyanamid Company
    Inventor: Sivaraman Raghu
  • Patent number: 4245102
    Abstract: Processes for reacting aryl vinyl compounds, nitriles, and halogens to provide imidoyl halides; processes for preparing amidine hydrohalides from the imidoyl compounds; processes for producing novel imidazolines from the amidine hydrohalides; processes for preparing novel amidoamines from the imidazolines; processes for preparing novel diamines from the amidoamines, together with novel nitrogen-containing products so produced, such products being useful for the production of various imidazothiazoles including tetramisole.
    Type: Grant
    Filed: August 2, 1979
    Date of Patent: January 13, 1981
    Assignee: American Cyanamid Company
    Inventor: Sivaraman Raghu
  • Patent number: 4240822
    Abstract: The invention is a method for the control of undesirable broadleaf weeds and grass weeds. More particularly, the invention relates to a method for controlling undesirable weeds by applying to the foliage thereof or to soil containing seeds of the undesirable weeds, a herbicidally effective amount of a 1H-benzotriazole or 2H-benzotriazole compound.
    Type: Grant
    Filed: December 4, 1978
    Date of Patent: December 23, 1980
    Assignee: American Cyanamid Company
    Inventors: Robert E. Diehl, Roger V. Kendall
  • Patent number: 4239708
    Abstract: There are provided substituted p-phenylene bis[imino(thiocarbonyl)] diphosphoramidic acid esters, a method for the preparation of said esters and unsubstituted derivatives thereof and a method for controlling helminths in warm-blooded animals by administering to said animals an anthelmintically effective amount of said unsubstituted or substituted p-phenylene bis[imino(thiocarbonyl)] diphosphoramidic acid ester.
    Type: Grant
    Filed: March 1, 1979
    Date of Patent: December 16, 1980
    Assignee: American Cyanamid Company
    Inventors: Goro Asato, John A. Pankavich
  • Patent number: 4230860
    Abstract: Processes for separating racemic trans-1,2-cyclic dicarboxylic acids by dissolving the racemic acid and a resolving agent such as cinchonidine in a solvent and cooling the solvent to form crystals rich in d-trans-1,2-cyclobutane dicarboxylic acid, the d-trans acid being recovered for use in preparing optically active materials.
    Type: Grant
    Filed: November 6, 1978
    Date of Patent: October 28, 1980
    Assignee: American Cyanamid Company
    Inventor: Sivaraman Raghu
  • Patent number: 4229383
    Abstract: There is provided a process for the preparation of a diphosphoramidate involving the reaction of a chlorophosphate with an alkali metal thiocyanate or ammonium thiocyanate in a water-immiscible solvent to form a cyanatidate, which is then reacted with an aqueous mixture of a phenylenediamine to yield said diphosphoramidate.
    Type: Grant
    Filed: June 11, 1979
    Date of Patent: October 21, 1980
    Assignee: American Cyanamid Company
    Inventor: Goro Asato
  • Patent number: 4224052
    Abstract: There are provided polysubstituted butanoic acids, esters and derivatives thereof, methods for preparing the same and herbicidal compositions employing said polysubstituted butanoic acids, esters and derivatives.
    Type: Grant
    Filed: May 5, 1978
    Date of Patent: September 23, 1980
    Assignee: American Cyanamid Company
    Inventor: Stephen S. Szucs
  • Patent number: 4221817
    Abstract: There is provided a method for the control of phytopathogenic fungi either by contacting the same with a phenylalkoxyphenylurea compound, or by applying said urea to the foliage of a plant susceptible to attack by fungi.
    Type: Grant
    Filed: April 16, 1979
    Date of Patent: September 9, 1980
    Assignee: American Cyanamid Company
    Inventor: Frank D. Tenne
  • Patent number: 4221816
    Abstract: A method is provided for the control of fungi attacking agronomic crops, either by contacting said fungi with a fungicidally effective amount of an alkoxyalkylurea compound, or by applying said urea to the foliage of a plant susceptible to attack by said fungi.
    Type: Grant
    Filed: April 16, 1979
    Date of Patent: September 9, 1980
    Assignee: American Cyanamid Company
    Inventor: Frank D. Tenne
  • Patent number: 4216149
    Abstract: This invention relates to novel derivatives of 4,5,6,7-tetrahydro-7-oxo(oxy)benzo[b]thiophen-4-amine which are useful as animal growth regulants, and a process for the preparation thereof. The above-identified compounds of this invention are also useful as intermediates for the preparation of 4,5,6,7-tetrahydro-7-oxo(oxy)benzo[b]thien-4-ylurea compounds.
    Type: Grant
    Filed: August 23, 1978
    Date of Patent: August 5, 1980
    Assignee: American Cyanamid Company
    Inventor: Goro Asato
  • Patent number: 4210760
    Abstract: Dehydrogenation processes comprising contacting 1-(2-alkoxyalkyl)-4-aryl-2-imidazolidone with catalysts comprising a noble metal adsorbed on a carrier to produce 1-(2-alkoxyalkyl)-4-aryl-4-imidazolin-2-ones, the dehydrogenation products being useful for synthesis with prochiral catalysts to provide enantiomerically enhanced imidazolidones.
    Type: Grant
    Filed: November 6, 1978
    Date of Patent: July 1, 1980
    Assignee: American Cyanamid Company
    Inventors: Sivaraman Raghu, Arthur K. Hoffmann
  • Patent number: 4199510
    Abstract: There is provided a process for the preparation of an amido or an ureido derivative of certain 4,5,6,7-tetrahydro-7-oxobenzo[b]thiophenes or certain 1,2,3,4-tetrahydro-4-oxonaphthalenes which can be employed as an animal growth regulant. The process comprises: oxidizing in the presence of a cobaltic carboxylate reactant and in the absence or presence of air, a compound having the formula: ##STR1## wherein R.sub.1 and R.sub.2 are each a substituent selected from the group consisting of alkanoyl C.sub.1 -C.sub.7, halogen-substituted alkanoyl C.sub.1 -C.sub.7, carboalkoxy C.sub.1 -C.sub.4, ##STR2## and ##STR3## R.sub.3 is selected from the group consisting of hydrogen and alkyl C.sub.1 -C.sub.4 ; R.sub.4 is selected from the group consisting of hydrogen, alkyl C.sub.1 -C.sub.8, alkanoyl C.sub.2 -C.sub.4, halogen-substituted alkanoyl (C.sub.2 -C.sub.
    Type: Grant
    Filed: April 4, 1978
    Date of Patent: April 22, 1980
    Assignee: American Cyanamid Company
    Inventors: Arnold Zweig, Robert G. Fischer, Jr.
  • Patent number: 4196297
    Abstract: Processes for the separation of enantiomers, such as those of 1-(2-methoxyethyl)-4-phenyl-2-imidazolidone, which comprises crystallizing a racemic mixture from a solution of the enriched enantiomer in a selective solvent.
    Type: Grant
    Filed: November 6, 1978
    Date of Patent: April 1, 1980
    Assignee: American Cyanamid Company
    Inventors: Nancy S. Kurose, Arnold Zweig
  • Patent number: 4196142
    Abstract: There are provided the compounds: 2-chloro-N-isopropyl-3',5'-dimethylacetanilide, 2-chloro-N-isopropyl-3',5'-diethylacetanilide, 2-chloro-N-isopropyl-3'-ethyl-5'-methylacetanilide, 2-chloro-N-isopropyl-3',4',5'-trimethylacetanilide, and 2-chloro-N-isopropyl-3',5'-dimethyl-4'-ethylacetanilide; a method for preparing the same; and a method for controlling undesirable plant species therewith.
    Type: Grant
    Filed: February 6, 1978
    Date of Patent: April 1, 1980
    Assignee: American Cyanamid Company
    Inventors: Albert W. Lutz, Robert E. Diehl
  • Patent number: 4191768
    Abstract: There are provided insecticidal pentadienone hydrazones and methods of preparation thereof. There is further provided a method for using the aforesaid compounds for the control of insects, especially Lepidopterous insects, and for the control of ants, Family Formicidae, especially fire ants.
    Type: Grant
    Filed: August 17, 1978
    Date of Patent: March 4, 1980
    Assignee: American Cyanamid Company
    Inventors: Thomas W. Drabb, Jr., James B. Lovell