Abstract: Artificial human skin is disclosed which is based on: (a) a microperforated membrane based on a hyaluronic acid derivative on which keratinocytes have been seeded and cultured; (b) an underlying non-woven tissue based on a hyaluronic acid derivative wherein fibroblasts have been seeded and left to proliferate.The artificial human skin may be used in medical, surgical, diagnostic and controlled release drug delivery applications. The artificial human skin may be safely frozen to -80.degree. C. or stored in liquid nitrogen in order to have a skin tissue bank.

Abstract: An analgesic controlled release dosage form containing: (a) 40-80 weight percent of an analgesic; (b) 10-30 weight percent of a pharmaceutically acceptable filler; and (c) 10-30 weight percent of a carrier base wherein the carrier base is formed from a high molecular weight hydroxypropyl methylcellulose, a water soluble binder and optionally a water insoluble binder.

Abstract: The invention provides a delayed-pulse controlled release pharmaceutical tablet having:(a) from 20 to 60 wt. % of a low molecular weight hydroxypropyl cellulose having a number average molecular weight of 70,000 to 90,000;(b) from 4 to 10 wt. % of a high molecular weight hydroxypropyl cellulose having a number average molecular weight of 1,100,000 to 1,200,000;(c) a pharmacologically acceptable amount of a medicament; and(d) an inert solid diluent.

Abstract: Threads (15) are handled in spiralling or covering machines with improved efficiency by replacing traditional bobbins (20) with double-coned bobbins (10) which include flanges (22) at both ends and by providing that the outside edges of the flanges do not project beyond the level of the unwinding thread.

Abstract: A three stages process for the preparation of solid thermoplastic compositions based on polyvinyl alcohol comprising the mixing in a mixer of a first charge, comprising the polyvinyl alcohol and solid plasticizers, with a second charge constituted by one or more hydroxylated organic compounds selected from glycols, glycol ethers and alkanolamines and at least a salt of an alkaline and/or alkaline earth metal, and a third charge containing at least one or more solid polyhydroxylated alcohols, glycols and glycolic ethers, liquid alkanolamines, organic or inorganic mineral acids, hydrated inorganic salts, polymers having a low molecular weight, stabilizers and possible mineral charges, is described.

Abstract: A controlled release antihyperglycemic tablet that does not contain an expanding polymer and comprising a core containing the antihyperglycemic drug, a semipermeable membrane coating the core and at least one passageway in the membrane.

Abstract: A controlled release pharmaceutical tablet containing antihyperglycemic drug and a hypoglycemic drug that does not contain an expanding or gelling polymer layer and comprising a core containing the antihyperglycemic drug and the hypoglycemic drug, a semipermeable coating membrane surrounding the core and at least one passageway in the membrane to allow the drugs to be released from the core.

Abstract: Composition whereby ceramic manufactured articles, obtained by molding pressing a ceramic mixture added with 1% to 10% TiO.sub.2 by wt., are colored in shades from yellow ocher to sienna, said composition being an aqueous or hydroalcoholic solution including tungsten and chromium inorganic compounds or organic derivatives, which is applied by controlled absorption to the surface of the ceramic material before firing.

Abstract: A pharmaceutical composition of omeprazole for oral administration is described which consists essentially of:(a) a pellet comprising an inert core component, a therapeutically effective amount of omeprazole, a surface active agent, a filler, a pharmaceutically acceptable alkaline agent and a binder; and(b) a single layer of coating on said pellet which comprises a layer of an enteric coating agent.

Abstract: A pay phone box structure includes a casing having a first side wall and a second side wall, a first supporting plate fixedly mounted on the first side wall of the casing and containing a plurality of first locking slots, a second supporting plate fixedly mounted on the second side wall of the casing and containing a plurality of second locking slots, a suspension bar secured to the second supporting plate and having a plurality of first locking hooks each detachably received in thesecond locking slots, a pivot plate pivotally mounted on the suspension bar and having an upper end portion and a lower end portion, a cover pivotally mounted on the casing and having a first side wall, a second side wall secured to the pivot plate, a closed wall and an open wall, a sliding plate slidably mounted on the first side wall of the cover and having a plurality of second locking hooks each detachably received in thefirst locking slots, and a U-shaped pivot bar pivotally mounted on the closed wall of the cover and having a

Abstract: An improved self-wound roll of a pressure sensitive adhesive coated laminate comprising a substrate which becomes dimensionally-unstable under normal processing conditions, e.g., printing, at least one layer comprising a continuous film of a normally dimensionally stable polymer adhesively fixed to one or both sides of the substrate thereby stabilizing it during processing, a transparent flexible release layer of a resin on the outwardly facing surface of the laminate, and a layer of a modified pressure sensitive adhesive on the inwardly facing surface of the substrate. The laminate can be processed without distortion, wound into rolls, unwound and applied to a surface to be decorated without delamination or shrinkage and without distortion of printed indicia, and it ultimately can be stripped without damage to the surface.

Abstract: A system and method for binding documents wherein the binder is reusable and is easy to use, said binding system comprising interlocking pieces that combined form a secure and reusable document binder.

Abstract: A positively controlled raising cylinder raising machine, having a plurality of raising cylinders, circumferentially arranged on a rotary framework, a toothed driving belt for driving the raising cylinders being engaged with a portion of the toothed circular periphery of the raising cylinder, said toothed driving belt being driven by a transmission toothed pulley arranged around a central portion of a circumference defined by the circular periphery of the raising cylinders and operatively coupled to a driving motor, the raising cylinder driving belt being moreover engaged with a pair of switching pulleys holding the driving belt tensioned, the switching pulleys being arranged inside the circular periphery of the raising cylinders on opposite sides of said transmission toothed pulley and near the transmission toothed pulley.

Abstract: An illuminated keypad key and method of manufacture thereof, having a light-permeable resin key top, a film having a pattern formed in one side thereof, the film being fixed to the upper and side surfaces of the transparent resin key top, cutting away portions of the film that extend beyond the lower periphery of the key top, and upper surface of a key operating portion made from transparent rubber or thermoplastic elastomer, being fixed to the underside surface of the key top by means of a transparent adhesive. The above mentioned film has a thickness of 100 mm-200 mm.

Abstract: Articles of manufacture are provided with a low surface energy, permanently non-stick, non-fouling and ice-phobic surface by a system of coating comprising applying a primary coating having a surface energy of 22-28 dynes/cm.sup.2 comprising a novel polymeric material having non-stick and hardness properties and then applying a top coating having lower surface energy of from about 18-21 dynes/cm.sup.2 comprising a siliconic polymer and interdigitating means to make the top coating permanent, the means preferably comprising a bi- or polyfunctional organic compound adapted to wet the surface of the primary coating and chemically or physically bond thereto and to couple to the siliconic polymeric substance in the top coating. The coated substrates are resistant to marking by graffiti, to adherence by marine fouling organisms, and frozen ice on the surface is easily removed.

Abstract: A synthetic, crystalline, porous material is disclosed, together with the related preparation process. Such material of zeolitic nature containing oxides of silicon, titanium and gallium corresponds, in the calcined and anhydrous state, to the following empyrical formula:pHGaO.sub.2 .multidot.qTiO.sub.2 .multidot.SiO.sub.2,wherein p has a value greater than zero and smaller than or equal to 0.050, and q has a value greater than zero and smaller than or equal to 0.025, and the H.sup.+ of HGaO.sub.2 can be at least partially replaceable or replaced by cations.

Abstract: A book having a storage tube attached thereto for storage of manipulatives for use with enjoyment of the book is disclosed.

Abstract: A method for making a solid agglomerate, having a preset size and shape, including a plurality of inert material particles, comprises the steps of: rotating the inert material particles, applying to the surface of the rotating particle an at least one component reactive resin, supplying the particles into a vessel holding each of the particles in contact with the adjoining particles at least for a time necessary to carry out the chemical reaction of the reactive resin, to provide a solid agglomerate.The invention also relates to a system for carrying out the method and the product obtained thereby.