Abstract: The invention concerns antiidiotypic antibodies comprising human constant regions, and murine variable regions bearing the internal image of human high molecular weight-melanoma associated antigen which have the specificity of said antibody. These antiidiotypic monoclonal antibodies have immune-regulatory functions and can therefore be used for diagnostic and therapeutic purposes, such as the treatment of melanoma.

Abstract: The present invention relates to oxime ethers of general formula (I) and to their isomers and isomer mixtures which are possible in which (a) X is an N atom and Y is an oxygen atom or NH, or (b) X is CH and Y is an oxygen atom, in which furthermore R.sub.1 is C.sub.1 -C.sub.4 alkyl; R.sub.2 is hydrogen, C.sub.1 -C.sub.4 alkyl cyclopropyl or cyano; R.sub.3 is cyano, substituted or unsubstituted C.sub.1 -C.sub.6 alkoxycarbonyl, substituted or unsubstituted di(C.sub.1 -C.sub.6 alkyl)aminocarbonyl, substituted or unsubstituted C.sub.1 -C.sub.6 alkyl-S(O).sub.n, substituted or unsubstituted aryl-S(O).sub.n, substituted or unsubstituted heteroaryl, substituted or unsubstituted heterocyclyl or substituted or unsubstituted heterocyclylcarbonyl; and R.sub.4 is C.sub.1 -C.sub.6 alkyl; C.sub.1 -C.sub.6 haloalkyl having 1 to 5 halogen atoms; C.sub.1 -C.sub.4 alkoxy-C.sub.1 -C.sub.2 alkyl; C.sub.2 -C.sub.6 alkenyl which is unsubstituted or substituted by 1 to 3 halogen atoms; C.sub.3 -C.sub.6 alkynyl; C.sub.3 -C.sub.

Abstract: Wood-penetrating fungi of the classes Ascomycotina and Deuteromycotina may be used very effectively to degrade pitch in wood forms used in the making of cellulosic products. Such fungi include but are not limited to the blue stain fungi. The process of Ascospore selection may be used to provide fungi which exhibit good growth on wood substrate while having little or no effects on substrate brightness, or even a positive effect on brightness. The treatment positively influences strength properties of ultimate products such as paper. In one embodiment the pulpwood or pulp is treated with a pitch degrading fungus of the genus Ophiostoma.

Abstract: There are described compounds of formula I*, ##STR1## wherein R.sub.1 is lower alkoxycarbonyl,R.sub.2 is secondary or tertiary lower alkyl or lower alkylthio-lower alkyl,R.sub.3 is phenyl that is unsubstituted or substituted by one or more lower alkoxy radicals, or C.sub.4 -C.sub.8 cycloalkyl,R.sub.4 is phenyl or cyclohexyl each substituted in the 4-position by unsaturated heterocyclyl that is bonded by way of a ring carbon atom, has from 5 to 8 ring atoms, contains from 1 to 4 hetero atoms selected from nitrogen, oxygen, sulfur, sulfinyl (--SO--) and sulfonyl (--SO.sub.2 --) and is unsubstituted or substituted by lower alkyl or by phenyl-lower alkyl,R.sub.5, independently of R.sub.2, has one of the meanings mentioned for R.sub.2, andR.sub.6, independently of R.sub.1, is lower alkoxycarbonyl,or salts thereof, provided that at least one salt-forming group is present.The compounds are inhibitors of retroviral aspartate protease and can be used, for example, in the treatment of AIDS.

Abstract: Unlike (4-cyclopropyl-6-methyl-pyrimidin-2-yl)-phenyl-amine of the known crystal modification A, (4-cyclopropyl-6-methyl-pyrimidin-2-yl)-phenyl-amine of crystal modification B of high eutectic purity (content at least 98%) and having a melting point of from 73.degree. C. to 75.degree. C., as a fungicidal active ingredient in plant-protection compositions, does not have a tendency to crystal growth. Such compositions have a high degree of storage stability and retain their original good suspensibility and dispersibility.

Abstract: The present invention relates to benzisoxazole compounds, pesticidal compositions containing them, and their preparations thereof.

Abstract: Aqueous, dispersant-containing wax- and polysiloxane-dispersions (P) containingas wax(A) at least one oxidized hydrocarbon wax of needle-penetration (according to ASTM D-1321).ltoreq.4 dim and optionally(B) at least one non-oxidized hydrocarbeon waxand as polydiorganosiloxane(C) at least one optionally amino-modified and/or non-ionically modified polydiorganosiloxane with a nitrogen-content<0.6% by weightand suitably a dispersant system which is(D) a non-ionogenic, cationic or amphoteric dispersant system,are suitable as finishing agents, in particular as highly permanent softeners and sewability improving agents, especially for textile white goods.

Abstract: Compositions of water insoluble U.V. absorbers can be improved by the addition of a non-ionic surfactant which is an addition product of ethylene oxide or propylene oxide or both ethylene oxide and propylene oxide, and a mixture of fatty alcohols, fatty acids or fatty esters having 7-20 carbon atoms, preferably 14-18 carbon atoms or either tristyrylphenol or distyrylphenol. Such compositions have a good storage stability and excellent shear stability when the substrate to be dyed is a yarn which is in packed form.

Abstract: The bacteria Pseudomonas fluorescens, Pantoea (Enterobacter) agglomerans, Bacillus cereus, and Xanthomonas campestris are useful in reducing the pitch content of pulps and pulpwoods used in making cellulosic products. Such bacteria are also useful in reducing the color staining by staining fungi of structural wood by inoculating the structural wood or log sources from which it is to be cut.

Abstract: The invention is related to compounds of formula (I) ##STR1## their salts and mixtures thereof wherein the symbols are as defined in the specification are useful as fibre-reactive dyestuffs for dyeing or printing hydroxy-group-containing or nitrogen-containing organic substrates.

Abstract: The compounds of the s-triazine series of formula I ##STR1## wherein the symbols R.sub.1, R.sub.2, R.sub.3, X and n possess the significances given in claim 1, are eminently suitable, when applied to textile material, as UV-absorbers, as resist agents for anionic dyes, and as stain blockers.

Abstract: There is described a process for the preparation of a compound of formula I ##STR1## in which process: a) a compound of formula II ##STR2## is reacted with an organolithium compound of formula IIILi--R.sub.7 (III)b) the resulting lithium complex is reacted with a compound of formula IVY.sub.1 --CO--CO--Y.sub.1 IVto form a compound of formula V ##STR3## c) that compound is, in either order, c1) oximated with O-methylhydroxylamine; or oximated with hydroxylamine and then methylated or fluoromethylated or difluoromethylated;c2) reacted with a chloroformic acid ester.X, m, Y, R.sub.1 to R.sub.3 and R.sub.7 are as defined in the description.

Abstract: A combination of a pharmacologically active compound and a water soluble monoester of a saturated or unsaturated (C.sub.6-18) fatty acid and a polyol, especially a saccharide, particularly as a solid solution of the active compound in the monoester.The solid solution is especially suitable for substantially water insoluble active compounds, particularly such polypeptides, e.g. ciclosporins and is in all desirable weight ratios miscible with water.The invention also, in particular, provides pharmaceutical compositions comprising a cyclosporin as active ingredient together with a fatty acid saccharide monoester.

Abstract: Finishing agent for the finishing treatment of textile fiber materials of natural origin and/or of regenerated cellulose and/or of synthetic fibers, containing i) a fine-grained, inorganic abrasive, ii) an anionic or non-ionic, low-foaming wetting agent, and iii) a non-ionic carrier, and the use of this finishing agent in the finishing treatment of textile fiber materials, whereby special surface effects are obtained.

Abstract: The invention provides a pharmaceutical composition containing a somatostatin analogue, and its use in the treatment of breast cancer. The pharmaceutical composition preferably contains lactic acid in addition to the somatostatin analogue and is better tolerated when administered by injection.

Abstract: A process of dyeing natural or synthetic polyamide fibres in an aqueous exhaustion dyebath comprising an anionic dyestuff, comprising the steps of1. immersing the fibres to be dyed in the aqueous dyebath which has a temperature of from 20.degree.-50.degree. C. and a pH of 7-11 (7-8.5 when the polyamide is wool); and2. raising the temperature to 110.degree. C. maximum and maintaining it there until exhaustion is substantially complete;there being added to the dyebath, either prior to the commencement of temperature raising or after an alkaline migration period at the boil, an ester of a C.sub.2 -C.sub.3 hydroxycarboxylic acid with a C.sub.2 -C.sub.6 glycol and up to 30% by weight of the ester of a tertiary amine which is essentially non-volatile under the process conditions.

Abstract: Compounds of formula I ##STR1## and possible isomers and isomeric mixtures thereof, wherein a)X is CH.sub.2 F or CHF.sub.2 ;Y is CH andZ is OMe, orb)X is CH.sub.2 F or CHF.sub.2 ;Y is a nitrogen atom andZ is OMe or NHCH.sub.3,and wherein alsom is 0, 1, 2, 3, 4 or 5 andU represents identical or different substituents selected from halogen, cyano, nitro, C.sub.1 -C.sub.12 alkyl, C.sub.3 -C.sub.8 cycloalkyl, C.sub.3 -C.sub.6 alkenyl, C.sub.3 -C.sub.6 alkenyloxyiminomethyl, C.sub.1 -C.sub.4 alkoxy, C.sub.1 -C.sub.4 alkoxyiminomethyl, C.sub.1 -C.sub.2 haloalkyl, C.sub.1 -C.sub.2 haloalkoxy, unsubstituted or substituted phenyl, unsubstituted or substituted phenoxy and unsubstituted or substituted benzyl or represents substituents at two adjacent positions of the phenyl ring of formula I that define a fused hydrocarbon bridge so as to form a larger hydrocarbon ring having up to 14 carbon atoms, are suitable for controlling and preventing microorganisms, insects and Acarina on plants.

Abstract: The present invention relates to the use of certain fungi in the reduction of the pitch and/or lignin content of cellulosic materials. In particular, the white rot fungi Schizophyllum commune, Trichaptum biforme and Phanerochaete gigantea are useful in reducing pitch and/or lignin, or both, which saves electrical energy during the mechanical refining of pulps and pulpwoods used in making cellulosic products.

Abstract: Fiber-reactive disazo dyes correspond to formula I, ##STR1## and they are present as free acids or in salt form. They are used as reactive dyes for dyeing or printing hydroxy-group-containing or nitrogen-containing organic substrates, especially leather or fibrous material, which consists of or contains natural or synthetic polyamides or natural or regenerated cellulose. The dyeings obtained have high fixation values and good light fastness.

Abstract: This invention relates to a method of obtaining a fungus of the species Ophiostoma piliferum by selective mating of strains of the fungus and selecting for an ascospore offspring which grows white or colorless, and has the ability to reduce pitch in Southern Yellow Pine wood chips.