Abstract: Apparatus and method to mitigate the spread of infectious material caused by coughing or sneezing are disclosed. The apparatus includes a bottom, a peripheral first duct and a peripheral second duct, and a top. The bottom has a first side and an opposing second side. The peripheral first duct is disposed on the first side of the bottom and around a portion of the periphery of the bottom. The peripheral second duct is disposed on the first side of the bottom and around a second portion of the periphery of the bottom. The peripheral first duct has a first cavity and the peripheral second duct has a second cavity. The top includes at least one opening configured to receive a nose and mouth of a user. The top is disposed above the first side of the bottom and is recessed below the peripheral first duct and the peripheral second duct. The bottom, the top, the peripheral first duct and the peripheral second duct define a third cavity.

Abstract: The present invention describes a method for the synthesis of enantiomerically pure 3-amidinophenylalanine derivatives, which are used as pharmaceutically effective urokinase inhibitors, by starting from 3-cyanophenylalanine derivatives. The methods of manufacture comprising only one synthesis step lead to new intermediates, namely 3-hydroxyamidino- and 3-amidrazonophenylalanine derivatives. These intermediates or their acetyl derivatives can be reduced into the desired 3-amidino-phenylalanine derivatives under gentle conditions (H2 or ammonium formiate, Pd/C (approx. 10%), ethanol/water, room temperature, normal pressure or also H2, Pd/C, AcOH or HCl/ethanol, 1-3 bar) in excellent yields and in an enantiomeric excess of up to 99.9%.

Abstract: The invention relates to isolated nucleic acid molecules comprising the sequence of a human cytomegalovirus microRNA. In another embodiment, the invention relates to single stranded DNA virus microRNA molecules comprising the sequence of a human cytomegalovirus microRNA. The invention also relates to the anti-DNA virus microRNA molecules.

Abstract: The invention concerns a process for the production of an electrically conductive structure on a carrier substrate comprising at least two conductor track portions spaced in a region of a width b over the entire width b at between 500 ?m and 1 ?m and a multi-layer film body. A conductive layer in the form of the conductor track portions is produced on the surface of the carrier substrate. A metallic coating forming the electrically conductive structure is deposited on the conductive layer by application of a flow of current in an electrolyte which contains a dissolved coating metal. In the production of the conductive layer the conductive layer is additionally produced in the form of conductor track extensions which are arranged on both sides of the conductor track portions and which are convexly curved away from the oppositely disposed conductor track portion.

Abstract: The application relates to a device in accordance with fluid technology (1), having at least one connecting body (2), through which at least one fluid-carrying conduit (5) extends and to which an elastic fluid-carrying hose (3) can be connected by means of a connecting arrangement (16). The connecting arrangement (16) contains a holding slide (25), which is displaceably seated on the connecting body (2) and through which a pass-through opening (32) extends, which has an insertion section (33) and a holding section (34), which is narrower than the latter. The connected fluid-carrying hose (3) itself has been directly inserted through the pass-through opening (32) of the holding slide (25) into the fluid-carrying conduit (5).

Abstract: The present invention is related to a composition capable of inhibiting the growth of tumoral cells of different histological origins and of activated endothelial cells. The components of said compositions are polypeptide fragments of the serralisins, corresponding to the C-terminal fragment, from the internal metionine trough the end of the molecule, which could be combined among them and optionally with the prodigiosins that potentiate the antitumoral effect of the composition. The prodigiosins in the composition could be at a concentration of 0.1-100 nM. The anti-proliferative action of this composition is mediated by apoptotic mechanism. It's “in vivo” administration has antitumoral, antiangiogenic and protective effect against malignant tumors.

Abstract: The present invention provides a physiologically compatible conductive agent comprising (a) a long chain water-soluble ionic polymeric thickening agent selected from the group consisting of a copolymer of methyl vinyl ether and maleic anhydride, carboxy polymethylene polymer, and mixtures thereof, present in an amount from about 0.05 wt. % to about 10 wt. %; (b) an unbranched or branched alcohol having from 1 to about 4 carbon atoms present in an amount up to about 70 wt. %; and (c) the balance water. The present invention also provides a physiologically compatible conductive agent comprising long chain water-soluble ionic polymeric thickening agent selected from the group consisting of a copolymer of methyl vinyl ether and maleic anhydride, carboxy polymethylene polymer, and mixtures thereof, present in an amount from about 0.05 wt. % to about 10 wt. %; (b) a surface tension reducing amount of a surfactant; and (c) the balance water.

Abstract: According to aspects illustrated herein, there are provided systems for conveying a sheet article into an intended pathway. The multi-way gate system for diverting sheets into multiple pathways in a sheet conveying device includes at least three pathways for directing the sheet from the sheet conveying member in a particular direction. A single gate plate is between the sheet conveying member and the pathways. The single gate plate is rotatable about a single axis to direct the sheet exiting the sheet conveying member toward one of the pathways.

Abstract: A method and an apparatus for monitoring the maximum distance between two objects, in particular between a child and its guardian, with the aid of two transceivers, the first of which periodically transmits status messages of a particular transmission power to the second, wherein an alarm is triggered in the second transceiver if the reception of the status messages decrease, and wherein a statement of the transmission power is concomitantly transmitted in each status message, are distinguished by the fact that the transmission power to be used for the next status message is determined by comparing the reception power with the transmission power stated in a status message and is transmitted back to the first transceiver in a confirmation message.

Abstract: An apparatus for transporting processed sheets within a printing device. The apparatus includes a compiler including a slot for receiving the processed sheets. The slot is defined at least in part by a paper guide. An elevator is in operative communication with the compiler. The elevator includes a stop for supporting the processed sheets and a drive mechanism for moving the stop and processed sheets supported thereby between a plurality of positions. The stop has a first position for initially receiving the processed sheets. The stop is movable from the first position in a generally upward direction to a second position for breaking adhesion between a processed sheet and the paper guide. The stop is movable in a generally downward direction from the second position to a third position.

Abstract: A preform production apparatus for precision press molding, which is downsized but can produce preforms at a lower cost, and a production method thereof using the apparatus are provided. The production method of a preform for precision press molding includes forming a molten glass body C by way of receiving and cutting molten glass A, being flowed continuously from a discharge nozzle 2, by a support member 1 or by way of allowing molten glass to fall in drops from a discharge nozzle 2 and receiving thereof by a support member 1, and transferring the molten glass body C from the support member 1 to a mold 5 by way of displacing the support member to near the mold 5, disposed not to be beneath the discharge nozzle 2, while increasing the viscosity of the molten glass body C on the support member 1.

Abstract: An electronic control device for a piezo-ceramic bending transducer designed as a trimorph, wherein a first voltage divider consisting of two resistor branches and powered by a first voltage source (Ust1) is provided, whose first resistor branch connects the first piezo-ceramic plate of the trimorph to its spacer layer. In addition, a second voltage divider is provided that consists of two resistor branches and the first resistor branch thereof connects the second piezo-ceramic plate of the trimorph to its spacer layer. The second resistor branch of the first voltage divider also forms the second resistor branch of the second voltage divider. Thus, by means of one voltage source, the one piezo-ceramic plate has an applied tensile stress and the other piezo-ceramic plate has an applied compressive stress, so that the flexural motion is reinforced by the two piezo-ceramic plates and thus only a small voltage has to be applied.

Abstract: A method of treating acne in a human in need thereof comprising administering systemically to said human a tetracycline compound in an amount that is effective to treat acne but has substantially no antibiotic activity, without administering a bisphosphonate compound.

Abstract: The present invention relates to free cholesterol analogs bearing a boron dipyrromethene difluoro (BODIPY) fluorophore in the side chain and methods of preparation. The compounds of the present invention can be used in fluorescence spectroscopy and fluorescence microscopy to visualize the exchange, distribution, and trafficking of free cholesterol between living cells and to monitor the movement of free cholesterol between ordered and disordered lipid domains in membranes.