Abstract: An autocatalytic process for the synthesis of chiral propargylic alcohols.

Abstract: The present invention provides a process for making an edible film having a substantially uniform distribution of components, which includes the steps of combining a water-based film polymer solution and a slurry-type mixture comprising a water-active component and a solvent; mixing the polymer solution and slurry-type mixture for about 10 minutes or less; dispensing the mixed solution and slurry-type mixture to form a film; and drying the film to evaporate the water and solvent. Films made by the process are also provided.

Abstract: Provided is a method of detecting the presence and quantitating the amount of glycogen from a biological sample. This method employs PAS staining with detection in the infrared range.

Abstract: The present invention is related to the development of peptides derived from the sequence HYRIKPTFRRLKWKYKGKFW (SEQ ID NO.: 13), showing amino acid substitutions, these peptides unable to bind to the lipopolysaccharides and bearing anti-tumoral and immunomodulatory capacities. These peptides alone or in combination are useful to treat cancer, and also in synergy with conventional therapies.

Abstract: To provide a substrate for information recording medium having various properties, in particular higher fracture toughness, required for application of the substrate for information recording medium of the next generation such as perpendicular magnetic recording system, etc. and a material with excellent workability for such purpose. A crystallized glass substrate for information recording medium, consisting of a crystallized glass which comprises one or more selected from RAl2O4 and R2TiO4 as a main crystal phase, in which R is one or more selected from Zn, Mg and Fe, and in which the main crystal phase has a crystal grain size in a range of from 0.5 nm to 20 nm, a degree of crystallinity of 15% or less, and a specific gravity of 3.00 or less.

Abstract: A composition of matter suitable for use in identifying chemical compounds that bind to voltage-dependent ion channel proteins, the composition comprising a screening protein that comprises an ion channel voltage sensor domain of the ion channel protein immobilized on a solid support.

Abstract: A system is provided herein which includes a closet flange insert and at least one spacer to be positioned between the closet flange insert and an installed closet flange. The closet flange insert includes a toilet connecting flange which extends radially outwardly from a through pipe. The through pipe is sized to be inserted into a pipe section of a closet flange. Each spacer includes spaced apart first and second faces, and spaced apart inner and outer edges extending between the first and second faces. The inner edge defines an opening extending through the body, the opening sized to permit passage therethrough of the through pipe of the closet flange insert but not the toilet connecting flange of the closet flange insert. With the subject invention, a system is provided which allows the closet flange insert to be mounted atop an installed closet flange flush with surrounding finished flooring.

Abstract: A frequency manipulator comprises a frequency transformer and a frequency retransformer. The frequency transformer receives each of at least one signal in a known band from at least one transmitter, transforms the known band of each signal into a predetermined band and forwards each signal in the predetermined band to a channel device. The frequency retransformer receives each signal from the channel device, retransforms the predetermined band of each signal to the known band and forwards each signal in the known band to at least one receiver.

Abstract: The packing according to the invention comprises: a container for holding said at least one object to be sterilized, having an inlet opening and a discharge opening via which said at least one object may pass into and out of said container, said container comprising a rigid part which comprises a peripheral wall bored with a multitude of small holes having dimensions smaller than those of the said at least one object, and a non-rigid part in a material porous to the sterilization fluid and non-porous to microbial contamination, this non-rigid part being able to contain said rigid part and to be sealed thereon; and at least one envelope made in a flexible and airtight material, which is vacuum sealing fitted on said container.

Abstract: A method for fast and accurate recognition of species contained in trace amounts in complex mixtures such as ambient air or biological fluids is taught based on the use in tandem of one or several differential mobility analyzers (DMAs) and possibly also a mass spectrometer (MS), all arranged in series. The two DMAs operate in different regions of the ion drag versus drift velocity curve (for instance, linear versus nonlinear regions), hence separating according to more than one independently discriminating parameters of the ion. Very high discrimination can be achieved even with a single stage of mass spectrometric separation by selecting a narrow range of ions with the DMA, and analyzing them in the MS, first without fragmentation, and then with fragmentation. This process does not require necessarily a tandem MS when fragmentation takes place in the inlet region of the MS.

Abstract: Disclosed is a resin composition having an excellent balance between shortness of curing time and longness of pot life. The resin composition contains (A) an organopolysiloxane having an alkenyl group, (B) an organopolysiloxane having a silicon atom-bonded hydrogen atom, (C) a hydrosilylation catalyst, (D) a silane coupling agent and (E) an unsaturated dicarboxylic acid ester. The component (B) contains (B-1) an organopolysiloxane having a molecular weight of not less than 5,000 but not more than 50,000 and (B-2) an organopolysiloxane having a molecular weight of not less than 100 but not more than 5,000, and the ratio of (B-2) to (B-1) is preferably not less than 0.01% by mass but not more than 20% by mass.

Abstract: The present invention relates to FTY720 analogs bearing a boron dipyrromethene difluoro (BODIPY) fluorophore in the alkyl side chain and methods of preparation. The compounds of the present invention can be used in fluorescence spectroscopy and fluorescence microscopy and in chromatography using fluorescence detection.