Patents Represented by Attorney Holmes Roberts & Owen, LLP
  • Patent number: 8109995
    Abstract: A method of making a replacement heart valve device whereby a fragment of biocompatible tissue material is treated and soaked in one or more alcohol solutions and a solution of glutaraldehyde. The dried biocompatible tissue material is folded and rehydrated in such a way that forms a two- or three-leaflet/cusp valve without affixing of separate cusps or leaflets or cutting slits into the biocompatible tissue material to form the cusps or leaflets. After the biocompatible tissue material is folded, it is affixed at one or more points on the outer surface to the inner cavity or a stent.
    Type: Grant
    Filed: August 8, 2008
    Date of Patent: February 7, 2012
    Assignee: Colibri Heart Valve LLC
    Inventors: David Paniagua, Eduardo Induni, Carlos Mejia, Francisco Lopez-Jimenez, R. David Fish
  • Patent number: 8106272
    Abstract: A cotton cultivar, designated L-9009-6, is disclosed. The invention relates to the seeds of cotton cultivar L-9009-6, to the plants of cotton L-9009-6 and to methods for producing a cotton plant produced by crossing the cultivar L-9009-6 with itself or another cotton variety. The invention further relates to hybrid cotton seeds and plants produced by crossing the cultivar L-9009-6 with another cotton cultivar.
    Type: Grant
    Filed: December 22, 2010
    Date of Patent: January 31, 2012
    Assignee: House of Agriculture Spirou AEBE
    Inventor: Georgios Sp. Spyrou
  • Patent number: 8106271
    Abstract: A cotton cultivar, designated L-1000, is disclosed. The invention relates to the seeds of cotton cultivar L-1000, to the plants of cotton L-1000 and to methods for producing a cotton plant produced by crossing the cultivar L-1000 with itself or another cotton variety. The invention further relates to hybrid cotton seeds and plants produced by crossing the cultivar L-1000 with another cotton cultivar.
    Type: Grant
    Filed: December 22, 2010
    Date of Patent: January 31, 2012
    Assignee: House of Agriculture Spirou AEBE
    Inventor: Georgios Sp. Spyrou
  • Patent number: 8080389
    Abstract: Disclosed herein are a Pichia pastoris-derived auto-inducible NPS promoter; a recombinant expression vector carrying the promoter and a nucleotide sequence, the sequence being operably linked to the promoter and coding for a recombinant protein; a host cell transformed or transfected with the recombinant expression vector; and a method for producing a recombinant protein, comprising culturing the host cell to express the recombinant protein and isolating the protein. The NPS promoter allows a recombinant protein of interest to be produced on a large scale without the need of any inducer.
    Type: Grant
    Filed: August 7, 2006
    Date of Patent: December 20, 2011
    Assignee: Korea Research Insitute of Bioscience and Biotechnology
    Inventors: Hong Weon Lee, Jung Oh Ahn, Joon Ki Jung, Eui Sung Choi, Chun Suk Kim, Eun Gyo Lee, Ji Yeon Hong, Hyeok Won Lee, Myoung Soo Park
  • Patent number: 8067567
    Abstract: The present invention relates to a transcriptional regulatory sequence with enhanced tumor-specificity and strength and a recombinant vector comprising the transcriptional regulatory sequence. More particularly, the present invention relates to a transcriptional regulatory sequence comprising a human telomere reverse transcriptase (hTERT) promoter linked to a nucleotide sequence that comprises one or more c-Myc binding sites and/or one or more Sp1 binding sites, and a recombinant vector comprising a certain gene that is operably linked to the above transcriptional regulatory sequence.
    Type: Grant
    Filed: February 27, 2004
    Date of Patent: November 29, 2011
    Assignee: Industry-Academic Cooperation Foundation, Yonsei University
    Inventors: Chae-Ok Yun, Joo-Hang Kim, Jai-Myung Yang
  • Patent number: 8066969
    Abstract: This invention relates, in general, to a method of producing magnetic oxide nanoparticles or metal oxide nanoparticles and, more particularly, to a method of producing magnetic or metal oxide nanoparticles, which comprises (1) adding a magnetic or metal precursor to a surfactant or a solvent containing the surfactant to produce a mixed solution, (2) heating the mixed solution to 50-6001 C to decompose the magnetic or metal precursor by heating so as to form the magnetic or metal oxide nanoparticles, and (3) separating the magnetic or metal oxide nanoparticles. Since the method is achieved through a simple process without using an oxidizing agent or a reducing agent, it is possible to simply mass-produce uniform magnetic or metal oxide nanoparticles having desired sizes compared to the conventional method.
    Type: Grant
    Filed: November 26, 2004
    Date of Patent: November 29, 2011
    Assignee: Industry-Academic Cooperation Foundation, Yonsei University
    Inventors: Jin-Woo Cheon, Jung-Wook Seo, Jae-Hyun Lee
  • Patent number: 8060217
    Abstract: The present invention relates to a neural device comprising wires transmitting and receiving electric signals. More specifically, the present invention relates to a structure of the neural device comprising wires which effectively obtain electric signals developed in nerve fibers and transmit electric stimuli to the nerve fibers. The neural device according to the present invention is connected to a processing module processing electric signals detected from nerve fibers, and the neural device is inserted in nerve fibers via nanowires to obtain electric signals from the nerve fibers, or inserted in the nerve fibers to transmit electric stimuli. The neural device may further provide with at least one through-hole and support. The neural device according to the present invention has an advantage that may obtain electric signals without killing nerve fibers or provide them with electric stimuli.
    Type: Grant
    Filed: February 18, 2008
    Date of Patent: November 15, 2011
    Assignee: Industry-Academic Cooperation Foundation, Yonsei University
    Inventors: Seung Han Park, Jong Il Hong, Jae Young Choi, Heon Jin Choi
  • Patent number: 8047850
    Abstract: A training tourniquet for use in training a user or another person, such as a medic, includes a non-functioning tensioning mechanism to model application of developing a tensile force in a strap of a tourniquet. The training tourniquet has particular application to training field personnel, such as medics and soldiers as to how to apply a tourniquet, without actually creating a compressive force that could damage a person's tissue during the training or practice sessions. In one embodiment, an inoperative windlass can be rotated to simulate the action necessary to create tension in a strap of a real tourniquet, however, the inoperative windlass spins around without actually tightening a strap of the training tourniquet.
    Type: Grant
    Filed: June 27, 2008
    Date of Patent: November 1, 2011
    Assignee: Phil Durango, LLC
    Inventors: Mark Esposito, Jonathan Bennett
  • Patent number: 8021399
    Abstract: A rod extension for extending a fusion construct allows a surgeon to connect a stabilization rod implant to at least a portion of a patient's spine, and also to connect the stabilization rod implant to an existing implant that has been previously installed in the patient. The existing fusion implant typically includes at least one existing pedicle screw, at least one existing rod, and at least one existing connector interconnecting the existing pedicle screw to the existing rod. The extension implant comprises a rod, an offset beam connected to the rod, and a clamp interconnected to the offset beam, wherein the clamp can be secured to the existing rod, thereby extending the fusion construct.
    Type: Grant
    Filed: July 19, 2006
    Date of Patent: September 20, 2011
    Inventor: Stephen Ritland
  • Patent number: 8011457
    Abstract: A drill bit assembly comprises a bit body intermediate a shank and a working face. The shank is adapted for connection to a drill string. The drill string comprising a fluid passage at least partially disposed within the body. A hammer assembly is movably disposed within the fluid passage along it central axis, the hammer assembly comprises a proximal end stabilized by a centralized upper bearing and a distal end stabilized by centralized a lower bearing. The distal end protrudes out of the working face and the hammer assembly comprises a carrier between the upper and lower bearings. Wherein, under normal drilling operations the carrier is adapted to resist a fluid pressure within the fluid passageway such that the fluid pressure will further extend the distal end of the hammer assembly from the working face by pushing on the carrier.
    Type: Grant
    Filed: February 26, 2008
    Date of Patent: September 6, 2011
    Assignee: Schlumberger Technology Corporation
    Inventors: David R. Hall, John Bailey, Scott Dahlgren
  • Patent number: 8007571
    Abstract: Produced natural gas containing carbon dioxide is dehydrated and chilled to liquefy the carbon dioxide and then fractionated to produce a waste stream of liquid carbon dioxide and hydrogen sulfide. Natural gas liquids may be first separated and removed before fractionation. After fractionation, the waste stream is pressurized and transmitted to a remote injection well for injection either for disposal of the waste stream and preferably to urge hydrocarbons toward the producing well. A hydrocarbon stream proceeds from fractionation to a methanol absorber system which removes carbon dioxide gas. The hydrocarbon stream is thereafter separated into at least hydrocarbon gas, nitrogen and helium. Some of the nitrogen is reintroduced into a fractionation tower to enhance the recovery of hydrocarbons. A methanol recovery system is provided to recover and reuse the methanol. The hydrocarbons are sold as natural gas and the helium is recovered and sold. Excess nitrogen is vented.
    Type: Grant
    Filed: August 22, 2008
    Date of Patent: August 30, 2011
    Inventor: Donald Leo Stinson
  • Patent number: 8007051
    Abstract: In one aspect of the invention, a pick comprises a carbide bolster disposed intermediate an impact tip and a shank assembly. The impact tip comprises a superhard material bonded to a carbide substrate, and the tip is bonded to the bolster opposing a base of the bolster. The shank assembly comprises a central axis, a first end that protrudes into a cavity formed in the base of the bolster, and also an inducible attachment mechanism disposed proximate the first end. The inducible attachment mechanism is adapted to attach the shank assembly to the carbide bolster and restrict movement of the shank assembly with respect to the carbide bolster. The attachment mechanism may restrict movement of the shank assembly in a direction parallel to the central axis.
    Type: Grant
    Filed: November 29, 2007
    Date of Patent: August 30, 2011
    Assignee: Schlumberger Technology Corporation
    Inventors: David R. Hall, Ronald B. Crockett, Jeff Jepson, Tyson J. Wilde, Jad Mills, Scott Dahlgren, Jonathan Marshall
  • Patent number: 7997661
    Abstract: In one aspect of the present invention, a high impact resistant excavation pick having a super hard material is bonded to a cemented metal carbide substrate at a non-planar interface. The cemented metal carbide substrate is bonded to a front end of a cemented metal carbide frustum. A tapered bore is formed in the base end of the carbide frustum opposite the front end and a steel shank with a tapered interface is fitted into the tapered bore.
    Type: Grant
    Filed: July 3, 2007
    Date of Patent: August 16, 2011
    Assignee: Schlumberger Technology Corporation
    Inventors: David R. Hall, Scott Dahlgren, Joe Fox
  • Patent number: 7994148
    Abstract: The present invention relates to a transmembrane delivery peptide derived from human in which a target protein may be easily delivered into cells, and a recombinant vector comprising a nucleic acid coding the peptide. More specifically, the present invention relates to the transmembrane delivery peptide having an amino acid sequence described in SEQ ID No. 1 including 11 amino acids of specific sites in amino acid sequences of human G protein alpha 12, and a recombinant vector comprising a nucleic acid coding the same, a transformant prepared by introducing said recombinant vector, and the like. Since transmembrane delivery peptides of the present invention can be efficiently delivered into cells, they may be usefully used for the purposes of delivering various target materials, including proteins, nucleic acid, drugs and the like.
    Type: Grant
    Filed: August 2, 2007
    Date of Patent: August 9, 2011
    Assignee: Industry-Academic Cooperation Foundation, Yonsei University
    Inventors: Ji-Hyung Chung, Yang-Soo Jang
  • Patent number: 7994791
    Abstract: A downhole induction resistivity assembly that comprises a downhole tool string component. The tool string component comprises an induction transmitter. The transmitter is adapted to induce an induction field in the surrounding formation. A first induction receiver is spaced apart from the transmitter and is adapted to measure the induction field. A magnetic field generating mechanism is disposed adjacent on either or both sides of the transmitter and adapted to guide the transmitter's signal into the formation. A second induction receiver is disposed in close proximity to the magnetic field generating mechanism and is adapted to measure the magnetic field generated by the mechanism.
    Type: Grant
    Filed: December 22, 2008
    Date of Patent: August 9, 2011
    Assignee: Schlumberger Technology Corporation
    Inventors: David R. Hall, Paula Turner, Harold L. Snyder, Clint Cook, Katie George
  • Patent number: D645360
    Type: Grant
    Filed: September 17, 2010
    Date of Patent: September 20, 2011
    Assignee: Simpel, LLC
    Inventors: Nathan C. Kiser, Ladd J. Marshall
  • Patent number: D646329
    Type: Grant
    Filed: September 24, 2010
    Date of Patent: October 4, 2011
    Assignee: Group Publishing, Inc.
    Inventors: Richard Allen Lawrence, Amy L. W. Nappa, Joan Louise Schultz, Jeffrey Scott White, Christine C. Yount Jones
  • Patent number: D647165
    Type: Grant
    Filed: January 18, 2011
    Date of Patent: October 18, 2011
    Assignee: Aquamira Technologies, Inc.
    Inventors: Dennis B. Brown, Richard O. Evans, Gary Cruikshank
  • Patent number: D650814
    Type: Grant
    Filed: January 19, 2011
    Date of Patent: December 20, 2011
    Assignee: Aquamira Technologies, Inc.
    Inventors: Dennis B. Brown, Richard O. Evans, Gary A. Cruikshank
  • Patent number: RE43251
    Abstract: A frame is formed of side walls that are extruded from vinyl. The side walls have interior channels. The side walls may be formed to effect a female-male connection between the ends of two adjoining side walls. Alternatively a locking member is provided that is sized to frictionally engage a selected channel. The side walls have a concrete retention fin positioned to extend away from the outer wall of the side wall to interconnect with the concrete as the and after the concrete cures. The frame may be formed into door jambs, doors, and the like. The frame may also be a window buck that may be formed into selected geometric shapes. Window bucks of different dimensions may be assembled on site by sawing.
    Type: Grant
    Filed: June 6, 2002
    Date of Patent: March 20, 2012
    Inventors: Justin J. Anderson, Bruce Anderson, Thayne Anderson, Audrey E. Anderson