Abstract: A compound of formula (I), or a pharmaceutically acceptable salt thereof: ##STR1## wherein R.sub.1 is hydroxy or amino;R.sub.2 is hydrogen or amino;R.sub.3 is hydrogen, hydroxymethyl or acyloxymethyl;R.sub.4 is hydrogen or (when R.sub.3 =H and Z is a bond or CH.sub.2) hydroxy, acyloxy, hydroxymethyl or acyloxymethyl;Z is a bond, or a group CHR.sub.8 wherein R.sub.8 is hydrogen, or (when R.sub.3 =R.sub.4 =H), R.sub.8 is hydroxy, acyloxy, hydroxymethyl or acyloxymethyl;R.sub.5 is a group of formula: ##STR2## wherein R.sub.6 and R.sub.7 are independently selected from hydrogen,C.sub.1-6 alkyl and optionally substituted phenyl.
Type:
Grant
Filed:
March 28, 1990
Date of Patent:
November 24, 1992
Assignee:
Beecham p.l.c.
Inventors:
Michael R. Harnden, David M. Duckworth, Halina T. Serafinowska
Abstract: Naval power cable comprises a plurality of insulated electrical conductors, at least a pair of strip cords, a water blocking layer, and a jacket layer. Each electrical conductor has a longitudinal extent and is helically intertwined with the other electrical conductors, to form a core conductor assembly having at least a pair of outer interstices adjacent to the insulated electrical conductors. Each strip cord is disposed in and extends along one of the outer interstices of the core conductor assembly. The water blocking layer is disposed about the core conductor assembly and the strip cords, and prevents passage of water along interstices about the electrical conductors. The jacket layer is disposed over and adjacent to the water blocking layer. To provide a power cable construction which has superior physical strength, toughness and resistance to damage, the water blocking layer and jacket layers, are formed from first and second cross-linkable materials, respectively.
Type:
Grant
Filed:
January 23, 1991
Date of Patent:
November 24, 1992
Assignee:
The Okonite Company
Inventors:
Howard C. Faust, Nicholas Adams, Wesley R. Kegerise, II
Abstract: A compound of formula (I) or a pharmaceutically acceptable salt thereof: ##STR1## in which one of X and Y represents hydrogen and the other represents Z, where Z is a group ##STR2## in which Q represents a 3-membered divalent residue completing a 5-membered aromatic ring and comprises one heteroatom selected from oxygen, nitrogen and sulphur or two heteroatoms selected from sulphur and nitrogen, any amino nitrogen being optionally substituted by a C.sub.1-2 alkyl, and at least one ring carbon atom being substituted by a group R.sub.1 ; or a group ##STR3## in which A.sub.1, A.sub.2 and A.sub.3 complete a 5-membered aromatic ring and A.sub.1 is oxygen or sulphur, A.sub.2 is CR.sub.2 and A.sub.3 is nitrogen or CH, or A.sub.2 is oxygen or sulphur, A.sub.1 is CH and A.sub.3 is CR.sub.2 ; and R.sub.1 and R.sub.2 are selected from, halogen, CN, OR.sub.4, SR.sub.4, N(R.sub.4).sub.2, NHCOR.sub.4, NHCOOCH.sub.3, NHCOOC.sub.2 H.sub.5, NHOR.sub.4 NHNH.sub.2, NO.sub.2, COR.sub.4, COR.sub.5, C.sub.2-4 alkenyl, C.sub.
Abstract: A construction element is disclosed for retaining a soil mass. In general, the construction element comprises a face panel and a plurality of protruding arms. The face panel has a forward wall, a rearward wall, side walls and a top and bottom wall. Such protruding arm extends from the rearward wall of the face panel, and each have an upper wall, lower wall, a back wall and side walls. The upper and lower walls of these protruding arms are each provided with engaging means for facilitating stacking of at least a portion of the protruding arm of one construction element, on top of at least a portion of the protruding arm of another construction element, and for preventing relative sliding movement therebetween. These construction elements can be used to construct a retaining wall and soil reinforcement subsystem, which comprises one or more free-standing retaining wall construction elements and at least one grid structure positioned behind each such construction element.
Abstract: Compounds of formula (II): ##STR1## wherein R.sub.4 ' is R.sub.4 whereinR.sub.4 is hydrogen, hydroxy, amino or OR.sub.5 whereinR.sub.5 is C.sub.1-6 alkyl, phenyl or phenyl C.sub.1-2 alkyl either of which phenyl moieties may be substituted by one or two halo, C.sub.1-4 alkyl or C.sub.1-4 alkoxy groups;or R.sub.4 ' is a group or atom convertible to R.sub.4 ; andR.sub.x is amino or protected amino;which are useful intermediates in the preparation of purine derivatives having antiviral activity.
Abstract: A laser based accelerometer system uses small motion induced shifts in frequency to measure the motion of an object without contact thereof. This technique is particularly useful for determining the vibratory and velocity characteristics of objects that are otherwise inaccessible for direct motion measurement by contact sensors.
Abstract: A compound of formula (I) or a pharmaceutically acceptable salt thereof: ##STR1## in which Z is a heterocyclic group ##STR2## in which Q represents a 3-membered divalent residue completing a 5-membered aromatic ring and comprises one or two heteroatoms selected from oxygen, nitrogen and sulphur, or three nitrogen atoms, any amino nitrogen being substituted by a C.sub.1-2 alkyl, cyclopropyl or propargyl group, and any ring carbon atom being optionally substituted by a group R.sub.1 ; or a group ##STR3## in which A.sub.1, A.sub.2 and A.sub.3 complete a 5-membered aromatic ring and A.sub.1 is oxygen or sulphur, one of A.sub.2 and A.sub.3 is CR.sub.2 and the other is nitrogen or CR.sub.3, or A.sub.2 is oxygen or sulphur, one of A.sub.1 and A.sub.3 is CR.sub.2 and the other is CR.sub.3 ; and R.sub.1, R.sub.2 and R.sub.3 are independently selected from hydrogen, halogen, CN, OR.sub.4, SR.sub.4, N(R.sub.4).sub.2, NHCOR.sub.4, NHCOOCH.sub.3, NHCOOC.sub.2 H.sub.5, NHOR.sub.4, NHNH.sub.2, NO.sub.2, COR.sub.4, COR.sub.
Abstract: A compound of the general formula (I): ##STR1## or a pharmaceutically acceptable ester thereof; or a pharmaceutically acceptable salt thereof, wherein,R.sup.o represents a substituted or unsubstituted aryl group or a substituted or unsubstituted benzofuranyl group,X represents a bond or --O--CH.sub.2 --,R.sup.1 represents a hydrogen atom or a moiety ##STR2## wherein R.sup.o and X are as defined above; R.sup.2 and R.sup.3 independently represent a hydrogen atom or an alkyl group,n represents an integer 1 or 2,Y represents a bond or a moiety --CH.sub.2 --O--, moiety A represents an aryl group,R.sup.4 represents a linking group, andR.sup.5 represents a substituted or unsubstituted, monocyclic or fused ring heterocyclic group, having up to four heteroatoms in each ring selected from, oxygen, nitrogen and sulphur; provided that R.sup.
Abstract: There is disclosed a metallurgical vessel, such as a steelworks converter, having a refractory brick lining and a probe opening passing a wall of the vessel for introducing a measuring and/or sampling probe. In order that the probe opening will get obstructed only minimally, if at all, and possible deposits of slag will be removed easily and quickly, the probe opening is provided with a lining of graphite or a graphite/alumina mixture.
Abstract: An improved apparatus for mounting artificial tree branches to an artificial tree trunk. A series of bracket guideways, each bridged by a horizontal pin, are adapted for pivotal engagement each with a branch member for movement between stowed and operative positions. Each branch mounts a hinge piece adjacent to one end adapted for pivotal engagement with the horizontal pin as the branch moves between stowed and operative positions, the hinge piece suspending the branch radially from the tree trunk when in an operative position. Snaps secure the branch in a groove on the hinge piece to restrict movement of the branch about the bracket when in either a stowed or an operative position. Extended bracket guideways and a hinge piece back stop also assist in securing the branch to the hinge piece and restricting radial movement of the branch about the bracket.
Abstract: An apparatus having a vacuum track, and a vacuum pallet for use therewith. The apparatus comprises a vacuum duct having a single vacuum pump and a plurality of ports which individually open when said vacuum pallet passes thereover. The pallet has a shoe which fits snugly over the port to facilitate evacuation of the pallet, and has small holes in the article-supporting surface through which the vacuum acts to hold an article in place thereon.
Abstract: An exercise float platform is formed of specifically dimensioned buoyant sections connected by flexing hinges to permit a user to perform an exercise routine in an aquatic environment. The buoyancy of the individual sections can be selectively adjusted depending on the weight distribution of the individual, or the exercise routine intensity. The exercise float permits the user to perform exercise routines in the water focused on the back, hips and stomach muscle groups along with allowing flexible upper and lower body workouts while either sitting below the water level or reclined above the water level. Separate elastic straps are applied to increase the level of resistance during exercise.
Abstract: A specific, illustrative modular stem system for lighting apparatus comprising hollow stems, each having first and second ends; a connector plug mounted at the first end; an in-line connector mounted inside the stem adjacent to the second end, the connector being configured for receiving the plug of another stem so as to permit connection of the stems end to end; a flexible joint so as to permit flexure of the stem upon the application of lateral forces to the stem system, means for dually securing the connector to the stem and the plug to the connector so as to facilitate connection of the stems end to end; and a lamp adjacent to the second end of the lowermost stem.
Type:
Grant
Filed:
March 2, 1992
Date of Patent:
September 22, 1992
Assignee:
Lightolier Division of The Genlyte Group, Inc.
Inventors:
Anthony C. Donato, Albert L. Newman, Alejandro Mier-Langner
Abstract: This invention provides an instant, dry powdered yogurt formulation which can be reconstituted into either a yogurt meal or a yogurt drink, and a process for making same. The formulation of this invention includes hydrocolloid gums, preferably a combination of xanthan gum and locust bean gum, and may include other gel systems such as a combination of carrageenan and diary protein, active protein, or certain type of maltodextrins. The powder can be reconstituted into a yogurt product of the desired thickness virtually instantaneously with agitation using a household blender, agitating by hand requires slightly longer times, but still under a minute. The composition is also useful for making a frozen or chilled yogurt product.
Abstract: This invention provides an instant, dry powdered yogurt formulation which can be reconstituted into either a yogurt meal or a yogurt drink, and a process for making same. The formulation of this invention includes a hydrocolloid gum, preferably a combination of xanthan gum and locust beam gum. This ingredient is important in making the formulation suitable to produce either a high quality meal or drink. A Lactobacillus culture and whey or another suitable dairy product are also included in the formulation. A process for preparing the formulation is described.