Abstract: A method for transferring a macromolecular complex to muscle cells by exsanguinating a region of the subject's microvasculature and delivering the complex to this region under high hydrostatic pressure. A balloon catheter having a balloon that extends substantially the full length of the cannula that is inserted into the subject is provided for use in the systemic delivery of macromolecular complex.

Abstract: In a stalk-type field probe, each of three resistive dipoles is formed with a resistive feedline on a common circuit board. Each circuit board comprises an elongated feedline section that extends through a cylindrical stalk, and a cross-arm that is disposed at a 54.7° angle relative to the elongation of the feedline section. The feedline sections are arranged to form an equilateral triangular prism, and the cross arms are arranged so that the dipole on each cross-arm is perpendicular to an imaginary plane to which the lines along which the elements of both of the other dipoles extend are parallel.

Abstract: In a timing chain drive, a hybrid driving sprocket, having roller-engaging teeth and side sprocket teeth, cooperates with a hybrid chain having rollers that mesh with the roller-engaging teeth and toothed link plates that mesh with the side sprocket teeth. A driven sprocket from which the chain travels toward the driving sprocket has a cyclically varying tooth pitch that compensates for tension variations due to cyclic variations in the rotational speed of the driving sprocket or to cyclic variations in the load applied to the driven sprocket. The driven sprocket can be a roller sprocket or a hybrid sprocket having roller-engaging teeth and side sprocket teeth for engagement with the teeth on the link plates of the chain.

Abstract: This invention provides CCI-779 cosolvent concentrates which are useful in preparing a parenteral formulation of rapamycin 42-ester with 3-hydroxy-2-(hydroxymethyl)-2-methylpropionic acid (CCI-779) following admixture with a diluent.

Abstract: Described herein are vaccines and the use of naked DNA and/or RNA encoding hemagglutinin (HA) from pandemic influenza, e.g., the 1918 H1N1 and/or the 1957 H2N2 and/or the 1968 H3N2 influenza A virus, as a vaccine component against present day and coming H1, H2, H3, H5, N1, N2 containing influenza A infections in humans and swine optionally with the naked DNA and/or RNA encoding Neuraminidase (NA) and/or matrix protein (M) and/or the nucleoprotein (NP) from pandemic influenza virus included. If the vaccine components are used as DNA or RNA vaccines with or without the corresponding protein, the codons can optionally be “humanized” using preferred codons from highly expressed mammalian genes and the administration of this DNA vaccine can be by saline or buffered saline injection of naked DNA or RNA, or injection of DNA plasmid or linear gene expressing DNA fragments coupled to particles. Addition of the matrix protein (M) and/or the nucleoprotein (NP) from the 1918 influenza strain is also disclosed.

Abstract: An oral methylphenidate powder which is reconstitutable into a final oral aqueous sustained release formulation containing at least about 50%, or at least about 80% by weight water based on the total weight of the suspension, is provided. The powder is a blend containing a combination of an uncoated methylphenidate-ion exchange resin complex, a barrier coated methylphenidate-ion exchange resin complex-matrix, and a water soluble buffering agent such that upon formed into an aqueous liquid formulation, the formulation has a pH in the range of about 3.5 to about 5, or about 4 to about 4.5. Following administration of a single dose of the oral aqueous methylphenidate suspension, a therapeutically effective amount of methylphenidate is reached in less than one hour and the composition provides a twelve-hour extended release profile.

Abstract: A process for preparing a formulation comprising a complex comprising an effective amount of ferrous iron bound to a pharmaceutically acceptable cationic resin and at least one pharmaceutically acceptable carrier is described. Such a formulation may optionally include other desirable dietary supplements including, e.g., vitamins, omega fatty acids, and/or fluoride. The formulation is particularly well adapted for pediatric use, but is also useful for use in adult populations.

Abstract: In a chain tensioner, an expansible ring is disposed in an internal groove formed in the inner wall of a plunger-accommodating hole near an open end thereof. The ring cooperates with grooves formed on the plunger to exert a ratchet action. The relationship between the angles of the surfaces of the internal groove and the grooves on the plunger allows the plunger to protrude, restricts retraction of the plunger on start-up of a chain transmission, but allows retraction when chain tension becomes excessive. In one embodiment, in which the ring is a C-ring, the tensioner housing can be formed with external threads for mounting in a threaded hole on a timing chain cover or other engine part. In other embodiments, the ring can have externally protruding levers for manipulation of the ring.

Abstract: The present invention relates to liposome formulations that are physically stable. In particular the present invention relates to steric stabilization of cationic liposomes by incorporating glycolipids into the liposomes. The stabilized liposomes can be used either as an adjuvant for antigenic components or as a drug delivery system. In particular the invention relates to vaccines with adjuvants in aqueous media for immunization, where the final product is stable.

Abstract: Provided is a method of manufacturing high-purity hafnium by using a hafnium sponge with reduced zirconium as the raw material in which the impurity content of Fe, Cr, and Ni, the impurity content of Ca, Na, and K, the impurity content of Al, Co, Cu, Ti, W, and Zn, the alpha dose, the impurity content of U and Th, the impurity content of Pb and Bi, and the content of C as a gas component contained in the hafnium are reduced. Based on this efficient and stable manufacturing technology, additionally provided are a high-purity hafnium material obtained from the foregoing high-purity hafnium, as well as a sputtering target, a gate insulation film and a metal gate thin film, which are formed from this material. This high-purity hafnium has a purity 6N or higher except Zr and gas components, wherein Fe, Cr and Ni are respectively 0.2 ppm or less, Ca, Na and K are respectively 0.1 ppm or less, and Al, Co, Cu, Ti, W and Zn are respectively 0.1 ppm or less.

Abstract: Provided is a roll unit for use in a surface treatment of a copper foil, wherein shaft sleeves are fitted to a roll shaft of a roll so that the roll shaft is rotatably supported by a bearing via the shaft sleeves. Additionally provided is a roll unit wherein the shaft sleeves consist of two sleeves, namely a roll-side sleeve arranged on a roll main body side and a tapered sleeve arranged on a shaft end side, an oil seal is arranged between the roll-side sleeve and a bearing box, and the tapered sleeve is supported by a bearing disposed in the bearing box.

Abstract: Provided is an amorphous film substantially comprised of indium, tin, calcium and oxygen, wherein tin is contained at a ratio of 5 to 15% based on an atomicity ratio of Sn/(In+Sn+Ca) and calcium is contained at a ratio of 0.1 to 2.0% based on an atomicity ratio of Ca/(In+Sn+Ca), and remnant is indium and oxygen. The film can be further crystallized by annealing at a temperature of 260° C. or lower in which resistivity of the film will be 0.4 m?cm or less. An ITO thin film for use as a display electrode or the like in a flat panel display can be made into an amorphous ITO film by way of sputter deposition without heating the substrate or adding water during deposition. This ITO film is characterized in that it will crystallize by annealing at a temperature of 260° C. or less, which is not such a high temperature, and have low resistivity after being crystallized. Thus, the present invention aims to provide a method of producing such a film and a sintered compact for producing such a film.

Abstract: A controlled combustion synthesis apparatus comprises an ignition system, a pressure sensor for detecting internal pressure, a nitrogen supply, a gas pressure control valve for feeding nitrogen and exhausting reaction gas, means for detecting the internal temperature of the reaction container, a water cooled jacket, and a cooling plate. A temperature control system controls the temperature of the reaction container by controlling the flow of cooling water supplied to the jacket and the cooling plate in response to the detected temperature. By combustion synthesizing, while controlling the internal pressure and temperature, the apparatus can synthesize a silicon alloy including 30-70 wt. % silicon, 10-45 wt. % nitrogen, 1-40 wt. % aluminum, and 1-40 wt % oxygen.

Abstract: A hafnium alloy target containing either or both of Zr and Ti in a gross amount of 100 wtppm-10 wt % in Hf, wherein the average crystal grain size is 1-100 ?m, the impurities of Fe, Cr and Ni are respectively 1 wtppm or less, and the habit plane ratio of the plane {002} and three planes {103}, {014} and {015} lying within 35° from {002} is 55% or greater, and the variation in the total sum of the intensity ratios of these four planes depending on locations is 20% or less. As a result, obtained is a hafnium alloy target having favorable deposition property and deposition speed, which generates few particles, and which is suitable for forming a high dielectric gate insulation film such as HfO or HfON film, and the manufacturing method thereof.

Abstract: The papermaking felt 10 of the present invention comprises a base body 20, a wet paper web side batt fiber layer 31, and a backside batt fiber layer 32, in which the wet paper web side batt fiber layer 31 is contained in high molecular weight elastic material and the backside batt fiber layer 32 includes a melting fiber.

Abstract: A wet paper web transfer belt 10 comprises a wet paper web side layer 20 having hydrophilic fibers 41 and a machine side layer 23. The machine side layer 23 is a batt layer having a core-sheath conjugate fiber comprising a core member made of nylon with a high melting point and a sheath member made of nylon with a lower melting point than the core member, and said machine side layer has a fused layer of the sheath member on the surface thereof.

Abstract: The present invention provides a papermaking felt which exhibits a good dewatering capability (water permeability) and resistance to flattening in a papermaking machine, and which is capable of improving surface smoothness of a wet paper web and has improved anti-dehairing property. A papermaking felt using a woven fabric in which at least one of an MD yarn and a CMD yarn arranged on a wet paper web side of a base body is a multifilament yarn which is a bundle of a plurality of filaments with fineness of 100 dtex or less and which is substantially without twisting or only loosely twisted and hence almost without twisting.

Abstract: The invention relates to compositions and methods that are useful in etching a metal surface. In particular, the invention relates to novel acid compositions and methods of using such compositions in etching a metal surface, preferably an aluminum surface prior to anodizing to dissolve impurities, imperfections, scale, and oxide. The compositions are effective in maintaining their etching capacity and in removing smut produced by the etching of a surface as well as in general cleaning.

Abstract: A rolled copper or copper alloy foil having a roughened surface formed of fine copper particles is obtained by subjecting a rolled foil to roughening plating with a plating bath containing copper sulfate (Cu equivalent of 1 to 50 g/L), 1 to 150 g/L of sulfuric acid, and one or more additives selected among sodium octyl sulfate, sodium decyl sulfate, and sodium dodecyl sulfate under the conditions of temperature of 20 to 50° C. and current density of 10 to 100 A/dm2. The foil has reduced craters, which are defects unique to rolled foils having a roughened surface, has high strength, adhesive strength with the resin layer, acid resistance and anti-tin plating solution properties, high peel strength, favorable etching properties and gloss level, and is suitable for producing a flexible printed wiring board capable of bearing a fine wiring pattern. A method of roughening the rolled foil is also provided.

Abstract: An electrolytic copper plating method characterized in employing a phosphorous copper anode having a crystal grain size of 1,500 ?m (or more) to 20,000 ?m in an electrolytic copper plating method employing a phosphorous copper anode. Upon performing electrolytic copper plating, an object is to provide an electrolytic copper plating method of a semiconductor wafer for preventing the adhesion of particles, which arise at the anode side in the plating bath, to the plating object such as a semiconductor wafer, a phosphorous copper anode for electrolytic copper plating, and a semiconductor wafer having low particle adhesion plated with such method and anode.