Patents Represented by Attorney Hultquist IP
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Patent number: 8138071Abstract: An isotopically-enriched, boron-containing compound comprising two or more boron atoms and at least one fluorine atom, wherein at least one of the boron atoms contains a desired isotope of boron in a concentration or ratio greater than a natural abundance concentration or ratio thereof. The compound may have a chemical formula of B2F4. Synthesis methods for such compounds, and ion implantation methods using such compounds, are described, as well as storage and dispensing vessels in which the isotopically-enriched, boron-containing compound is advantageously contained for subsequent dispensing use.Type: GrantFiled: October 27, 2010Date of Patent: March 20, 2012Assignee: Advanced Technology Materials, Inc.Inventors: Robert Kaim, Joseph D. Sweeney, Oleg Byl, Sharad N. Yedave, Edward E. Jones, Peng Zou, Ying Tang, Barry Lewis Chambers, Richard S. Ray
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Patent number: 8101355Abstract: A method for cloning and expressing a target gene by homologous recombination, and more particularly a method for cloning and expressing a target gene by homologous recombination, wherein a host cell transformed with a recombinant vector and a plasmid containing a recombinase system is introduced with a linear DNA fragment comprising a target gene and a sequence having homology to the recombinant vector. Because complicated genetic engineering steps, such as the restriction enzyme treatment and ligation of a vector and a target gene, are not required, the cloning of a gene can be performed without needing a high degree of skill, and enzyme cost can be reduced. The inventive method can be effectively used for the massive, high-speed cloning and protein expression of genes, and the disclosed pRMT-iTGR system can be used as an analytical means for improving high-efficiency recombinase.Type: GrantFiled: September 14, 2009Date of Patent: January 24, 2012Assignee: Korea Research Institute of Bioscience and BiotechnologyInventors: Seung-Goo Lee, Jae-Jun Song, Jeong-Min Lee, Jae-Seok Ha
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Patent number: 8097607Abstract: The invention features low-dosage rifalazil compositions which are useful for the treatment of bacterial infections.Type: GrantFiled: September 23, 2003Date of Patent: January 17, 2012Inventors: Bernard E. Cabana, Arthur F. Michaelis, Gary P. Magnant, Chalom B. Sayada
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Patent number: 8093140Abstract: Germanium, tellurium, and/or antimony precursors are usefully employed to form germanium-, tellurium- and/or antimony-containing films, such as films of GeTe, GST, and thermoelectric germanium-containing films. Processes for using these precursors to form amorphous films are also described. Further described is the use of [{nBuC(iPrN)2}2Ge] or Ge butyl amidinate to form GeTe smooth amorphous films for phase change memory applications.Type: GrantFiled: October 31, 2008Date of Patent: January 10, 2012Assignee: Advanced Technology Materials, Inc.Inventors: Philip S. H. Chen, William Hunks, Tianniu Chen, Matthias Stender, Chongying Xu, Jeffrey F. Roeder, Weimin Li
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Patent number: 8084078Abstract: A multi-spectral imaging process, comprising: selecting colors for presentation in a target visualization regime; determining correspondence of said colors in the target visualization regime to colors in a source visualization regime; and fabricating a product in the source visualization regime having a coloration that produces a predetermined visual presentation of the object in the target visualization regime. Such process can be utilized to fabricate articles having coloration including a blaze orange coloration in a source visualization regime involving a human observer and a camouflage pattern in a target visualization regime involving an animal observer.Type: GrantFiled: April 17, 2007Date of Patent: December 27, 2011Inventor: Jeff Burrell
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Patent number: 8065745Abstract: A funereal garment for use in providing a full and healthy appearance to a corpse lacking tissue necessary for such appearance. The garment includes a main garment body with compartments positioned to receive shaped inserts, wherein the compartments and shaped inserts are provided in sufficient number and location to provide a supplementary mass and enhanced physiological conformation to a corpse dressed in such garment, simulative of a full and healthy appearance of the corpse in relation to the corpse without such garment. The inserts may be inflatable articles or forms of predetermined shape, adapted for placement and retention in the compartments of the garment, so that the funereal garment provides the corpse with an aesthetic appearance for viewing and funeral/internment ceremonies.Type: GrantFiled: June 26, 2009Date of Patent: November 29, 2011Inventor: Melvin Huell
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Patent number: 8067341Abstract: Carbon nanotube (CNT) films, patterns and biochips and methods of making the same are provided. Such a biochip comprises a bio-receptor attached by means of an exposed chemical functional group on a surface of a high density CNT film or pattern produced by repeated lamination of CNTs on a substrate with exposed amine groups. Various types of CNT-biochips may be fabricated by bonding of bio-receptors to a CNT pattern (or film) containing exposed carboxyl groups or modified by various chemical functional groups. Further, the CNT-biochip may be used to measure an electrical or electrochemical signal using both conductor and semiconductor properties of the CNT, thereby not needing labeling. Upon fluorescent measurement of DNA hybridization using such a CNT-DNA chip it is possible to show more distinct signals useful for genotyping, mutation detection, pathogen identification and the like.Type: GrantFiled: March 19, 2004Date of Patent: November 29, 2011Inventors: Hee Tae Jung, Sang Yup Lee, Dae Hwan Jung, Byung Hun Kim, Young Koan Ko
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Patent number: 8067552Abstract: The present invention relates to a method for separating and purifying a target protein, a method for preparing a target protein, and a method for bioconversion by a whole cell enzyme or a partially purified enzyme. According to the present invention, when the sHSPs are added in cultivation, separation and purification processes for preparing a target protein, the target protein can be obtained at high yields by preventing the loss of protein by proteases. Also, when sIISPs are added in a reaction process using a whole cell enzyme or a partially purified enzyme, the yield of bioconversion using enzyme can be increased by preventing the loss of enzyme by proteases.Type: GrantFiled: May 23, 2005Date of Patent: November 29, 2011Assignee: Korea Advanced Institute of Science and TechnologyInventors: Sang Yup Lee, Mee Jung Han
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Patent number: 8062965Abstract: An isotopically-enriched, boron-containing compound comprising two or more boron atoms and at least one fluorine atom, wherein at least one of the boron atoms contains a desired isotope of boron in a concentration or ratio greater than a natural abundance concentration or ratio thereof. The compound may have a chemical formula of B2F4. Synthesis methods for such compounds, and ion implantation methods using such compounds, are described, as well as storage and dispensing vessels in which the isotopically-enriched, boron-containing compound is advantageously contained for subsequent dispensing use.Type: GrantFiled: March 15, 2011Date of Patent: November 22, 2011Assignee: Advanced Technology Materials, Inc.Inventors: Robert Kaim, Joseph D. Sweeney, Oleg Byl, Sharad N. Yedave, Edward E. Jones, Peng Zou, Ying Tang, Barry Lewis Chambers, Richard S. Ray
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Patent number: 8057597Abstract: The present invention consists in obtaining, with the capsule described, a vertical gradient favorable for diamond growth that prevails over any radial gradient by means of heating discs placed at the ends of the heating area, which implies a considerable control over the growth conditions. More specifically, in regard to the rate of growth, it allows for a better control of the quality of large crystals. Another important novelty is to use a source of carbon with a special design formed by cylindrical and conical hollows (graphite, amorphous carbon, diamond or other) with a solvent metal with a number of gases that are introduced in the capsule. Also, a nitrogen scavenger is used to avoid the formation of nitrides, carbides and oxides that are harmful for the growth and that as a significant novelty is placed outside the reaction area.Type: GrantFiled: August 16, 2005Date of Patent: November 15, 2011Assignee: Instituto de Monocristales, S.L.Inventors: Ramon Martin Parrondo, Dmitri Bagriantsev
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Patent number: 8052903Abstract: A defect-free vitreous carbon material having a three-dimensional (x,y,z) size in which each of the x, y and z dimensions exceeds twelve millimeters. A process of making such vitreous carbon material employs a three-dimensional fiber mesh that vaporizes at elevated temperature, in which the mesh is impregnated with a polymerizable resin and thereafter the resin is cured. During the initial stage(s) of pyrolysis, the mesh volatilizes to yield a residual network of passages in the cured resin body that thereafter allows gases to escape during pyrolysis of the cured resin material to form the vitreous carbon product. As a result, it is possible to form defect-free vitreous carbon material of large size, suitable for use in structural composites, and product articles such as sealing members, brake linings, electric motor brushes, and bearing members.Type: GrantFiled: December 25, 2006Date of Patent: November 8, 2011Inventor: Christopher Whitmarsh
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Patent number: 8053571Abstract: This invention relates to methods, compositions, and apparatuses for producing macrocyclic compounds. First, one or more reactants are provided in a reaction medium, which are capable of forming the macrocyclic compound through a desired reaction pathway that includes at least cyclization, and which are further capable of forming undesired oligomers through a undesired reaction pathway that includes undesirable oligomerization. Oligomerization of such reactions in the reaction medium is modulated to reduce formation of undesired oligomers and/or to reduce separation of the undesired oligomers from the reaction medium, relative to a corresponding unmodulated oligomerization reaction, thereby maximizing yields of the macrocyclic compound. The macrocyclic compound so formed is then recovered from the reaction medium. Preferably, the macrocyclic compound spontaneously separates from the reaction medium via phase separation.Type: GrantFiled: May 3, 2010Date of Patent: November 8, 2011Inventors: Thomas E. Johnson, Billy T. Fowler
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Patent number: 8053375Abstract: An ultra low k dielectric film, including a silicon film containing porosity deriving from a porogen, as formed from a precursor silane and a porogen, wherein the precursor silane has a water content below 10 ppm, based on total weight of the precursor silane, and/or the porogen has a water content below 10 ppm, based on total weight of the porogen. In one implementation, the precursor silane is diethoxymethylsilane, and the porogen is bicyclo[2.2.1]-hepta-2,5-diene having a trace water content below 10 ppm, based on total weight of said bicyclo[2.2.1]-hepta-2,5-diene. These super-dry reagents are unexpectedly polymerization-resistant during their delivery and deposition in the formation of ultra low k films, and are advantageously employed to produce ultra low k films of superior character.Type: GrantFiled: October 27, 2007Date of Patent: November 8, 2011Assignee: Advanced Technology Materials, Inc.Inventors: Chongying Xu, Jeffrey F. Roeder, Thomas H. Baum, Steven M. Bilodeau, Scott Battle, William Hunks, Tianniu Chen
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Patent number: 8048413Abstract: Compositions which deliver adsorbents, alone or in combination with active drug “degrading molecules,” in a site-specific manner to the intestine, and which eliminate or at least lower the concentration of residual unwanted material within the intestine, are disclosed. Methods of treatment using the compositions are also disclosed. The material to be eliminated can include residual active antibiotics, metabolites, bacterial or other toxins, and drugs which cause side effects in the gastrointestinal tract. The adsorbents can be formulated in capsules, tablets or any acceptable pharmaceutical composition, and are ideally designed to specifically release the adsorbents in a programmed manner at a specific site of the intestinal tract. The programmed delivery prevents adsorbents from interfering with the normal absorption process of a given molecule after oral absorption, until it reaches the lower part of the small intestine.Type: GrantFiled: May 17, 2007Date of Patent: November 1, 2011Inventors: Helene Huguet, Antoine Andremont, Nicolas Tsapis, Elias Fattal
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Patent number: 8048584Abstract: The present invention relates to microfibrous fuel cell sub-bundle structures, fuel cell bundles and fuel cell assemblies formed by such fuel cell sub-bundles and bundles. Specifically, a fuel cell sub-bundle is provided, which comprises multiple microfibrous fuel cells. Each microfibrous fuel cell comprises: (a) a hollow microfibrous membrane separator comprising an electrolyte medium, (b) an inner electrocatalyst layer in contact with an inner surface of such membrane separator, (c) an outer electrocatalyst layer in contact with an outer surface of such membrane separator, and (d) an individual current collector in electrical contact with the inner surface of such membrane separator. Each of such multiple microfibrous fuel cells is in electrical contact with a common current collector at the outer surface of its membrane separator.Type: GrantFiled: May 18, 2007Date of Patent: November 1, 2011Assignee: Microcell CorporationInventors: Ray R. Eshraghi, Michael W. Riley
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Patent number: 8034407Abstract: A multi-step method for depositing ruthenium thin films having high conductivity and superior adherence to the substrate is described. The method includes the deposition of a ruthenium nucleation layer followed by the deposition of a highly conductive ruthenium upper layer. Both layers are deposited using chemical vapor deposition (CVD) employing low deposition rates.Type: GrantFiled: May 17, 2007Date of Patent: October 11, 2011Assignee: Advanced Technology Materials, Inc.Inventors: Bryan C. Hendrix, James J. Welch, Steven M. Bilodeau, Jeffrey F. Roeder, Chongying Xu, Thomas H. Baum
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Patent number: 8030064Abstract: The present invention relates to a method for expressing a target protein on an exosporium forming the outermost surface of bacterial spores. More particularly, the present invention relates to a method for expressing a target protein on the surface of cells and spores using an exosporium as a matrix for surface expression, and methods for the production of a protein array, the production of antibodies, the separation of a certain substance from a mixture, bioconversion, and the improvement of a target protein, which are characterized by using the cells or spores having the target protein that was expressed on the surface by the above expression method.Type: GrantFiled: December 30, 2003Date of Patent: October 4, 2011Assignees: Korea Advanced Institute of Science and Technology, Genofocus, Inc.Inventors: Sang Yup Lee, Tae Jung Park, Jong Pil Park, Seok Jae Lee, Jae-Gu Pan, Heung-Chae Jung, Soo-Keun Choi
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Patent number: D648150Type: GrantFiled: July 9, 2010Date of Patent: November 8, 2011Inventor: Taku Kumazawa
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Patent number: D648858Type: GrantFiled: January 27, 2010Date of Patent: November 15, 2011Inventors: Paul Hayton, Christopher Althorpe
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Patent number: D649652Type: GrantFiled: January 15, 2010Date of Patent: November 29, 2011Inventors: Paul Hayton, Christopher Althorpe