Abstract: A system and method for providing credit to a customer based on preliminary use of an account indicating that the customer is a good credit risk by providing to a customer an offer for a preliminary account associated with an action, facilitating a loan transaction between the customer and another party, receiving value from another party to initially fund the customer's preliminary account, providing the preliminary account to the customer, monitoring the preliminary account for the at least one predetermined action, repaying the another party the value received to initially fund the customer's preliminary account, and providing a credit account to the customer based on performance of the action.

Abstract: A method and system for collecting and transmitting data across or through a firewall using HTTP and/or XML between computer systems that do not otherwise grant access to each other. A method and system for preparing data reports using data and report generation modules using HTTP and/or XML between computer systems.

Abstract: The recoverable intra-uterine system comprises a housing capable of containing one or a plurality of elements selected from among the group comprising an embryo, male and/or female gametes, a fertilized oocyte, and unfertilized ovum and a combination of these elements, the housing having along an axis a distal end and a proximal end, and a device for holding the recoverable intra-uterine device in the uterus. The holding device is arranged at the proximal end of the housing and includes at least one holding arm in the uterine cavity capable of taking at least two positions: —one free position in which at least one holding arm is separated from the axis; and —a retracted position in which at least one holding arm is substantially parallel to the axis. Use in medically assisted reproduction techniques.

Abstract: Functional assays that detect the effect of a particular compound or compounds on the activation of at least one human T2R polypeptide are provided. These assays include e.g., assays which detect the effect of said compound on intracellular calcium, second messengers such as cAMP, cGMP, current e.g., by use of voltage-clamp or patch-clamp, techniques, fluorescence polarization or FRET assays, and the like. These assays are useful in identifying compounds that putatively elicit or modulate (inhibit or enhance) bitter taste in human subjects, e.g. bitter taste blockers. The effect of identified compounds on taste may be further evaluated in human or animal taste tests.

Abstract: A fluid reservoir for retaining a particular fluid against an environmental force is disclosed. The fluid reservoir includes a three dimensional porous body that has a plurality of reservoir capillaries formed therein and has a transport volume and effective capillarity in the force direction for the particular fluid when the porous body is oriented in a predetermined orientation. The fluid reservoir also includes at least one lateral indentation in a surface of the porous body. Each of the at least one lateral indentation defines opposing reservoir surfaces each having a lateral surface component orthogonal to the force direction. The at least one lateral indentation is configured so that at least a majority of the reservoir capillaries have a force-aligned length component that is less than the effective capillarity for the particular fluid.

Abstract: A method and system for collecting and managing feedback from account users via account statements by providing data for a user interface displaying a statement of financial transactions and one or more feedback mechanisms, receiving feedback information via a selected feedback mechanism, and storing the received feedback information and feedback information received from other users. Authorization information for a desired financial transaction that is dependent, at least in part, on the received feedback information, may also be provided.

Abstract: A method and associated vessel for transferring liquids from offshore tankers to an onshore storage facility. The system utilizes a flexible pipe that is heavier than the water it displaces, such that the flexible pipe sinks to the sea floor even when empty. The high weight and relatively small profile of the flexible pipe avoids the need for anchoring the pipe to the sea floor. The flexible pipe has a bending radius of no greater than five feet, such that it can be wound onto spools onboard the vessel, and can be rapidly deployed, retrieved, and reused in another location. The vessel containing the spools of flexible pipe is dynamic positioning capable, and contains the equipment required to establish a position onshore to receive the liquid being transferred; means to deploy, retrieve, and repair the flexible pipe; and means to receive liquid from a tanker vessel and pump that liquid through the flexible pipe to the onshore storage facility.

Abstract: An apparatus for extracting wave energy may include a watercraft, a pendulum and an energy converter. The watercraft may be configured to roll in response to wave action and may have roll characteristics that are tunable to characteristics of the wave action. The pendulum may be supported by the watercraft to enable the pendulum to swing in response to the wave action. An energy converter may be configured to convert the relative movement of the pendulum and watercraft into electrical energy. The pendulum may also be tunable to characteristics of the wave action.

Abstract: The present invention provides immunostimulatory combinations. Generally, the immunostimulatory combinations include a TLR agonist and a TNF/R agonist. Certain immunostimulatory combinations also may include an antigen.

Abstract: The present invention is directed to therapeutic methods using IL-6 antagonists such as an Ab1 antibody or antibody fragment having binding specificity for IL-6 to prevent or treat disease or to improve survivability or quality of life of a patient in need thereof. In preferred embodiments these patients will comprise those exhibiting (or at risk of developing) an elevated serum C-reactive protein level, reduced serum albumin level, elevated D-dimer or other coagulation cascade related protein(s), cachexia, fever, weakness and/or fatigue prior to treatment. The subject therapies also may include the administration of other actives such as chemotherapeutics, anti-coagulants, statins, and others.

Abstract: The present invention relates to the discovery that the T1R receptors assemble to form functional taste receptors. Particularly, it has been discovered that co-expression of T1R1 and T1R3 results in a taste receptor that responds to umami taste stimuli, including monosodium glutamate. Also, it has been discovered that co-expression of the T1R2 and T1R3 receptors results in a taste receptor that responds to sweet taste stimuli including naturally occurring and artificial sweeteners. Also the present invention relates to the use of hetero-oligomeric taste receptors comprising T1R1/T1R3 and T1R2/T1R3 in assays to identify compounds that respectively respond to umami taste stimuli and sweet taste stimuli. Further, the invention relates to the constitutive of cell lines that stably or transiently co-express a combination of T1R1 and T1R3; or T1R2 and T1R3; under constitutive or inducible conditions.

Abstract: The present invention relates to the discovery that specific human taste receptors in the T2R taste receptor family respond to particular bitter compounds, i.e., chlorogenic lactone compounds that contribute at least partially to the bitter taste of many coffee beverages. The present invention further relates to the use of these receptors in assays for identifying ligands that modulate the activation of these taste receptors by chlorogenic lactones and related compounds and which may be used as additives and/or removed from foods, beverages and medicinals in order to modify (block) T2R-associated bitter taste. A preferred embodiment is the use of the identified compounds as additives in coffee and coffee-flavored foods, beverages and medicinals.

Abstract: MHC Class I-restricted peptides derived from the tumor associated antigen, survivin, which peptides are capable of binding to Class I HLA molecules at a high affinity, capable of eliciting INF-?-producing cells in a PBL population of a cancer patient and capable of in situ detection of cytotoxic T cells in a tumor tissue, therapeutic and diagnostic composition comprising the peptide and uses thereof.

Abstract: The invention provides an external in-line device (“Subnet Box”) placed between a network and an access point to achieve secure Wi-Fi communications without needing to modify the access point. The Subnet Box comprises an embedded token and will authenticate users based on pre-stored access rights. In at least one embodiment of the invention, the Subnet Box comprises: a first communications port for intercepting data packets communicated to and from a wired communications network; a second communications port for intercepting data packets communicated to and from a wireless access point, wherein the wireless access point is an edge device of the wired communications network; a database comprising a number of serial numbers each associated with a client token and a secret cryptographic key; and a processor for determining whether a computing device having a client token can access the wired communications network via the wireless access point.

Abstract: Newly identified mammalian taste-cell-specific G protein-coupled receptors, and the genes and cDNA encoding said receptors are described. Specifically, T1R G protein-coupled receptors active in taste signaling, and the genes and cDNA encoding the same, are described, along with methods for isolating such genes and for isolating and expressing such receptors. Methods for representing taste perception of a particular tastant in a mammal are also described, as are methods for generating novel molecules or combinations of molecules that elicit a predetermined taste perception in a mammal, and methods for simulating one or more tastes. Further, methods for stimulating or blocking taste perception in a mammal are also disclosed.

Abstract: The present invention includes compositions and methods for delivering one or more unit dosage units by modifying the release profile of an optionally coated drug-resin complex suspended in an ionic salt solution, wherein the optionally coated drug-resin complex includes one or more active agents loaded on to one or more ion-exchange resin particles, and wherein the release of the one or more active agents is modulated by the one or more ionic salts in solution.