Patents Represented by Attorney, Agent or Law Firm Incyte Genomics
  • Human serine carboxypeptidase
    Patent number: 6379913
    Abstract: The present invention provides a human serine carboxypeptidase (CPEPT) and polynucleotides which identify and encode CPEPT. The invention also provides expression vectors, host cells, agonists, antibodies, and antagonists. The invention also provides methods for treating disorders associated with expression of CPEPT.
    Type: Grant
    Filed: April 26, 1999
    Date of Patent: April 30, 2002
    Assignee: Incyte Genomics, Inc.
    Inventors: Olga Bandman, Phillip R. Hawkins, Jennifer L. Hillman, Preeti Lal, Surya K. Goli
  • Human S-adenosyl-L-methionine methyltransferase
    Patent number: 6379722
    Abstract: The invention provides a human S-adenosyl-L-methionine methyltransferase (SAM-MT) and polynucleotides which identify and encode SAM-MT. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of SAM-MT.
    Type: Grant
    Filed: September 8, 1998
    Date of Patent: April 30, 2002
    Assignee: Incyte Genomics, Inc.
    Inventors: Olga Bandman, Preeti Lal, Neil C. Corley, Purvi Shah
  • CAF1-related protein
    Patent number: 6376651
    Abstract: The invention provides a human CAF1-related protein (CAFRP) and polynucleotides which identify and encode CAFRP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of CAFRP.
    Type: Grant
    Filed: June 25, 1999
    Date of Patent: April 23, 2002
    Assignee: Incyte Genomics, Inc.
    Inventors: Jennifer L. Hillman, Neil C. Corley, Henry Yue
  • Mammalian toxicological response markers
    Patent number: 6372431
    Abstract: The present invention relates to mammalian nucleic acid and protein molecules comprising a plurality of nucleic acid and protein molecules. The mammalian nucleic acid molecules can be used as hybridizable array elements in a microarray in diagnostic and therapeutic applications including detecting metabolic and toxicological responses, and in monitoring drug mechanism of action. The protein molecules can be used in a pharmaceutical composition. The present invention also relates to methods for screening compounds and therapeutics for metabolic responses indicative of a toxic compound or molecule.
    Type: Grant
    Filed: November 19, 1999
    Date of Patent: April 16, 2002
    Assignee: Incyte Genomics, Inc.
    Inventors: Mary Jane Cunningham, Gary B. Zweiger, Matthew R. Kaser, Scott R. Panzer, Jeffrey J. Seilhamer, Henry Yue, Mariah R. Baughn, Yalda Azimzai, Preeti Lal
  • Glutathione S-transferase homolog
    Patent number: 6368810
    Abstract: The invention provides a human glutathione S-transferase (GSTH) and polynucleotides which identify and encode GSTH. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating and preventing disorders associated with expression of GSTH.
    Type: Grant
    Filed: April 16, 1999
    Date of Patent: April 9, 2002
    Assignee: Incyte Genomics, Inc.
    Inventors: Jennifer L. Hillman, Neil C. Corley, Purvi Shah
  • Detection of altered expression of genes regulating cell proliferation
    Patent number: 6368794
    Abstract: The present invention relates to polynucleotides comprising genes that regulate cell proliferation. The present invention also relates to a method for diagnosing or monitoring the treatment of a disease characterized by the altered expression of genes that regulate cell proliferation in a sample.
    Type: Grant
    Filed: January 15, 1999
    Date of Patent: April 9, 2002
    Assignee: Incyte Genomics, Inc.
    Inventors: Steven Daniel, James Gilmore, Susan G. Stuart, Laura L. Stuve
  • Translational regulator
    Patent number: 6365714
    Abstract: The invention provides a human translational regulator (TRANAC) and polynucleotides which identify and encode TRANAC. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of TRANAC.
    Type: Grant
    Filed: December 17, 1998
    Date of Patent: April 2, 2002
    Assignee: Incyte Genomics, Inc.
    Inventors: Jennifer L. Hillman, Phillip R. Hawkins
  • Ubiquitin-like conjugating protein
    Patent number: 6365358
    Abstract: The invention provides a human ubiquitin-like conjugating protein (UBCLE) and polynucleotides which identify and encode UBCLE. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of UBCLE.
    Type: Grant
    Filed: June 9, 1999
    Date of Patent: April 2, 2002
    Assignee: Incyte Genomics, Inc.
    Inventors: Jennifer L. Hillman, Purvi Shah, Neil C. Corley
  • Antibody to human testin and methods of making and using
    Patent number: 6358711
    Abstract: The invention provides a human testin (HTES) and polynucleotides which identify and encode HTES. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of HTES.
    Type: Grant
    Filed: May 16, 2000
    Date of Patent: March 19, 2002
    Assignee: Incyte Genomics, Inc.
    Inventors: Preeti Lal, Karl J. Guegler, Neil C. Corley
  • H-rev107-like protein
    Patent number: 6359123
    Abstract: The present invention provides a human H-rev107-like protein (HREVP) and polynucleotides which identify and encode HREVP. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding HREVP and a method for producing HREVP. The invention also provides for agonists, antibodies, or antagonists specifically binding HREVP, and their use, in the prevention and treatment of diseases associated with expression of HREVP. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding HREVP for the treatment of diseases associated with the expression of HREVP. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding HREVP.
    Type: Grant
    Filed: February 14, 1997
    Date of Patent: March 19, 2002
    Assignee: Incyte Genomics, Inc.
    Inventors: Olga Bandman, Surya K. Goli
  • Cell surface glycoproteins
    Patent number: 6358923
    Abstract: The invention provides human cell surface glycoproteins (CSGP) and polynucleotides which identify and encode CSGP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of CSGP.
    Type: Grant
    Filed: December 22, 1999
    Date of Patent: March 19, 2002
    Assignee: Incyte Genomics, Inc.
    Inventors: Henry Yue, Neil C. Corley, Karl J. Guegler, Gina A. Gorgone, Mariah R. Baughn
  • Tumor-associated antigen
    Patent number: 6350581
    Abstract: The present invention provides a human tumor-associated antigen (TUAN) and polynucleotides which identify and encode TUAN. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. In addition, the invention provides methods for producing TUAN and for treating or preventing disorders associated with expression of TUAN.
    Type: Grant
    Filed: January 8, 1999
    Date of Patent: February 26, 2002
    Assignee: Incyte Genomics, Inc.
    Inventors: Olga Bandman, Surya K. Goli, Purvi Shah, Neil C. Corley
  • Human prostate-associated protease
    Patent number: 6350448
    Abstract: The present invention provides a human prostate-associated protease (HUPAP) and polynucleotides which identify and encode HUPAP. The invention also provides expression vectors, host cells, antibodies, antagonists, and antisense molecules. The invention also provides methods for treating disorders associated with expression of HUPAP.
    Type: Grant
    Filed: January 7, 2000
    Date of Patent: February 26, 2002
    Assignee: Incyte Genomics, Inc.
    Inventors: Olga Bandman, Preeti Lal
  • Human cornichon molecule
    Patent number: 6348576
    Abstract: The invention provides a human cornichon protein (CORN) and polynucleotides which identify and encode CORN. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating and preventing disorders associated with expression of CORN.
    Type: Grant
    Filed: August 2, 1999
    Date of Patent: February 19, 2002
    Assignee: Incyte Genomics, Inc.
    Inventors: Jennifer L. Hillman, Neil C. Corley, Purvi Shah
  • SH3-containing proteins
    Patent number: 6326158
    Abstract: The invention provides a human SH3-containing protein (HS3C) and polynucleotides which identify and encode HS3C. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of HS3C.
    Type: Grant
    Filed: April 19, 1999
    Date of Patent: December 4, 2001
    Assignee: Incyte Genomics Inc.
    Inventors: Olga Bandman, Karl J. Guegler, Preeti Lal
  • Human sodium-dependent phosphate cotransporter
    Patent number: 6326207
    Abstract: The present invention provides a human sodium-dependent phosphate cotransporter (NAPTR) and polynucleotides which identify and encode NAPTR. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding NAPTR and a method for producing NAPTR. The invention also provides for agonists, antibodies, or antagonists specifically for NAPTR. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding NAPTR for the treatment of diseases associated with the expression of NAPTR. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding NAPTR. The invention also provides a method for treating disorders associated with decreased phosphate levels by administering NAPTR and a method for treating disorders associated with increased phosphate levels by administering antagonists to NAPTR.
    Type: Grant
    Filed: September 8, 1999
    Date of Patent: December 4, 2001
    Assignee: Incyte Genomics, Inc.
    Inventors: Preeti Lal, Olga Bandman
  • Tapasin-like protein
    Patent number: 6322977
    Abstract: The invention provides a mammalian nucleic acid sequence and fragments thereof. It also provides for the use of the nucleic acid sequence for the characterization, diagnosis, evaluation, treatment, or prevention of conditions, diseases and disorders associated with gene expression and for the production of a model system. The invention additionally provides expression vectors and host cells for the production of the protein encoded by the mammalian nucleic acid sequence.
    Type: Grant
    Filed: April 14, 1999
    Date of Patent: November 27, 2001
    Assignee: Incyte Genomics, Inc.
    Inventors: Preeti Lal, Matthew R. Kaser, Mariah R. Baughn
  • Human citrate synthase homolog
    Patent number: 6323328
    Abstract: The invention provides a human citrate synthase homolog (HUCS) and polynucleotides which identify and encode HUCS. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of HUCS.
    Type: Grant
    Filed: November 13, 1997
    Date of Patent: November 27, 2001
    Assignee: Incyte Genomics, Inc.
    Inventors: Jennifer L. Hillman, Preeti Lal, Neil C. Corley, Purvi Shah
  • Human lysophospholipase
    Patent number: 6319701
    Abstract: The present invention provides a human lysophospholipase (NHLP) and polynucleotides which identify and encode NHLP. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. In addition, the invention provides methods for producing NHLP and for treating or preventing disorders associated with expression of NHLP.
    Type: Grant
    Filed: December 15, 1998
    Date of Patent: November 20, 2001
    Assignee: Incyte Genomics, Inc.
    Inventors: Jennifer L. Hillman, Purvi Shah, Lynn E. Murry
  • Human selenium-binding protein
    Patent number: 6312895
    Abstract: The present invention provides a human selenium-binding protein (HSEBP) and polynucleotides which identify and encode HSEBP. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding HSEBP and a method for producing HSEBP. The invention also provides for agonists and antibodies specifically binding HSEBP, and their use in the prevention and treatment of diseases associated with expression of HSEBP. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding HSEBP for the treatment of diseases associated with the expression of HSEBP. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding HSEBP.
    Type: Grant
    Filed: June 2, 1998
    Date of Patent: November 6, 2001
    Assignee: Incyte Genomics, Inc.
    Inventors: Olga Bandman, Phillip R. Hawkins