Patents Represented by Attorney, Agent or Law Firm Incyte Pharmaceuticals, Inc.
  • Patent number: 6277572
    Abstract: The present invention provides a human NADH-D protein subunit (NDS) and polynucleotides which encode NDS. The invention also provides expression vectors, host cells, agonists, antisense molecules, antibodies, or antagonists. The invention also provides methods for treating disorders associated with expression of NDS.
    Type: Grant
    Filed: December 9, 1998
    Date of Patent: August 21, 2001
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Jennifer L. Hillman, Purvi Shah, Preeti Lal
  • Patent number: 6242214
    Abstract: The invention provides human GTPase-associated proteins (GPAP) and polynucleotides which identify and encode GPAP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of GPAP.
    Type: Grant
    Filed: April 21, 1998
    Date of Patent: June 5, 2001
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Olga Bandman, Preeti Lal, Karl J. Guegler, Neil C. Corley, Chandra Patterson
  • Patent number: 6242179
    Abstract: The invention provides human phosphatases (HPA) and polynucleotides which identify and encode HPA. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating disorders associated with expression of HPA.
    Type: Grant
    Filed: December 17, 1997
    Date of Patent: June 5, 2001
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Purvi Shah, Jennifer L. Hillman, Neil C. Corley, Preeti Lal
  • Patent number: 6197512
    Abstract: The invention provides human myosin heavy chain-like proteins (MHCP) and polynucleotides which identify and encode MHCP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating disorders associated with expression of MHCP.
    Type: Grant
    Filed: December 17, 1998
    Date of Patent: March 6, 2001
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Olga Bandman, Henry Yue, Neil C. Corley, Purvi Shah
  • Patent number: 6194186
    Abstract: The invention provides a human protein kinase (PK) and kinase inhibitors (PKI) and polynucleotides which identify and encode PK and PKI. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of PK and PKI.
    Type: Grant
    Filed: November 25, 1997
    Date of Patent: February 27, 2001
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Preeti Lal, Jennifer L. Hillman, Olga Bandman, Neil C. Corley, Purvi Shah
  • Patent number: 6184357
    Abstract: The present invention provides a human prostate-specific kallikrein (HPSK) and polynucleotides which identify and encode HPSK. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding HPSK and a method for producing HPSK. The invention also provides for agonists, antibodies, or antagonists specifically binding HPSK, and their use, in the prevention and treatment of diseases associated with the expression of HPSK. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding HPSK for the treatment of diseases associated with the expression of HPSK. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding HPSK.
    Type: Grant
    Filed: March 3, 1999
    Date of Patent: February 6, 2001
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Olga Bandman, Surya K. Goli
  • Patent number: 6180342
    Abstract: The invention provides human vacuolar proton ATPase subunits (VATPS) and polynucleotides which identify and encode VATPS. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of VATPS.
    Type: Grant
    Filed: June 17, 1998
    Date of Patent: January 30, 2001
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Olga Bandman, Y. Tom Tang, Preeti Lal, Neil C. Corley, Karl J. Guegler, Chandra Patterson
  • Patent number: 6177546
    Abstract: The invention provides a human glutathione-S-transferase (HGST) and polynucleotides which identify and encode HGST. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of HGST.
    Type: Grant
    Filed: December 22, 1999
    Date of Patent: January 23, 2001
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Henry Yue, Neil C. Corley, Purvi Shah
  • Patent number: 6174702
    Abstract: The invention provides a human PINCH protein homolog (PINCH-PH) and polynucleotides which identify and encode PINCH-PH. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of PINCH-PH.
    Type: Grant
    Filed: January 16, 1998
    Date of Patent: January 16, 2001
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Preeti Lal, Karl J. Guegler, Neil C. Corley
  • Patent number: 6171843
    Abstract: The invention provides human peptidyl-prolyl isomerases (HPPIP) and polynucleotides which identify and encode HPPIP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of HPPIP.
    Type: Grant
    Filed: June 1, 1998
    Date of Patent: January 9, 2001
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Olga Bandman, Preeti Lal, Neil C. Corley, Chandra Patterson, Mariah R. Baughn
  • Patent number: 6165767
    Abstract: The invention provides human protein phosphatase-related molecules (PPRM) and polynucleotides which identify and encode PPRM. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of PPRM.
    Type: Grant
    Filed: March 20, 1998
    Date of Patent: December 26, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Preeti Lal, Henry Yue, Neil C. Corley, Karl J. Guegler, Mariah Baughn
  • Patent number: 6156523
    Abstract: The invention provides human serine/threonine protein kinases (HSTK) and polynucleotides which identify and encode HSTK. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of HSTK.
    Type: Grant
    Filed: September 16, 1998
    Date of Patent: December 5, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Olga Bandman, Y. Tom Tang, Surya K. Goli, Neil C. Corley, Karl J. Guegler, Gina A. Gorgone, Jennifer L. Hillman
  • Patent number: 6143544
    Abstract: The invention provides a new human lysophospholipase (JHLP) and polynucleotides which identify and encode IHLP. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating inflammation and disorders associated with expression of IHLP.
    Type: Grant
    Filed: June 19, 1997
    Date of Patent: November 7, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Jennifer L. Hillman, Purvi Shah, Neil C. Corley, Lynn E. Murry
  • Patent number: 6143870
    Abstract: The present invention provides nucleotide and amino acid sequences that identify and encode a novel thrombin receptor homolog (TRH) expressed in human liver. The present invention also provides for antisense molecules to the nucleotide sequences which encode TRH, diagnostic tests based on TRH encoding nucleic acid molecules, expression vectors for the production of purified TRH, antibodies capable of binding specifically to TRH, hybridization probes or oligonucleotides for the detection of TRH-encoding nucleotide sequences, genetically engineered host cells for the expression of TRH, and antagonists, antibodies and inhibitors with specific binding activity for the polypeptide TRH.
    Type: Grant
    Filed: December 21, 1998
    Date of Patent: November 7, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Roger Coleman, Janice Au-Young, Olga Bandman, Jeffrey J. Seilhamer
  • Patent number: 6139837
    Abstract: The invention provides a human ATP-dependent RNA helicase (ADRH-1) and polynucleotides which identify and encode ADRH-1. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of ADRH-1.
    Type: Grant
    Filed: September 9, 1998
    Date of Patent: October 31, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Olga Bandman, Karl J. Guegler, Neil C. Corley, Purvi Shah
  • Patent number: 6136314
    Abstract: The present invention provides a human histone fusion protein (HFP) and polynucleotides which identify and encode HFP. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. In addition, the invention also provides methods for producing HFP and for treating or preventing disorders associated with expression of HFP.
    Type: Grant
    Filed: July 14, 1999
    Date of Patent: October 24, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Jennifer L. Hillman, Surya K. Goli
  • Patent number: 6135941
    Abstract: The invention provides human immune system associated proteins (HISAP) and polynucleotides which identify and encode HISAP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of HISAP.
    Type: Grant
    Filed: March 27, 1998
    Date of Patent: October 24, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Jennifer L. Hillman, Preeti Lal, Y. Tom Tang, Henry Yue, Janice Au-Young, Neil C. Corley, Karl J. Guegler, Mariah R. Baughn
  • Patent number: 6136955
    Abstract: The present invention provides a human SMT3-like protein (HSMTH) and polynucleotides which identify and encode HSMTH. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. In addition, the invention provides methods for producing HSMTH and for treating or preventing disorders associated with expression of HSMTH.
    Type: Grant
    Filed: October 14, 1998
    Date of Patent: October 24, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Jennifer L. Hillman, Purvi Shah
  • Patent number: 6132714
    Abstract: The invention provides a human growth-associated methyltransferase (GAMT) and polynucleotides which identify and encode GAMT. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of GAMT.
    Type: Grant
    Filed: August 24, 1999
    Date of Patent: October 17, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Y. Tom Tang, Henry Yue, Karl J. Guegler, Purvi Shah
  • Patent number: 6132973
    Abstract: The invention provides human regulatory molecules and polynucleotides (collectively designated HRM) which identify and encode them. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention further provides methods for diagnosing, preventing, and treating disorders associated with expression of human regulatory molecules.
    Type: Grant
    Filed: January 20, 1999
    Date of Patent: October 17, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Preeti Lal, Jennifer L. Hillman, Olga Bandman, Purvi Shah, Janice Au-Young, Henry Yue, Karl J. Guegler, Neil C. Corley