Patents Represented by Attorney Irving Holtzman
  • Patent number: 4273721
    Abstract: Tertiary amine esters e.g. ##STR1## their acid addition salts and their quaternary ammonium compounds.
    Type: Grant
    Filed: September 21, 1977
    Date of Patent: June 16, 1981
    Assignee: Bristol-Myers Company
    Inventor: Ara Nersesian
  • Patent number: 4260596
    Abstract: An edible unit dosage form comprising an outer shell made of a material containing a major portion of mannitol and a liquid or gel center which may contain a therapeutically effective amount of a medicament. The shell is sealed to the atmosphere with a suitable sealing material. Method for preparing the unit dosage form is also disclosed.
    Type: Grant
    Filed: August 13, 1979
    Date of Patent: April 7, 1981
    Assignee: Bristol-Myers Company
    Inventor: Leonard Mackles
  • Patent number: 4248227
    Abstract: A flexible unit dispensing device for a fluid comprising a squeezable hollow bulb portion and a cylindrical nozzle. The internal diameter of the nozzle is no smaller than 0.120 inches and the length of nozzle being such as to reach to the area of the rectal columns when the device is inserted in the anal canal.
    Type: Grant
    Filed: May 14, 1979
    Date of Patent: February 3, 1981
    Assignee: Bristol-Myers Company
    Inventor: Ralph H. Thomas
  • Patent number: 4241048
    Abstract: A composition containing a therapeutically effective amount of powdered benzocaine suspended in an essentially anhydrous carrier and further containing a copolymer of a vinylpyrrolidone and an alpha-olefin as a crystal growth suppressing agent.
    Type: Grant
    Filed: May 1, 1979
    Date of Patent: December 23, 1980
    Assignee: Bristol-Myers Company
    Inventors: Taras Durbak, Ara Nersesian
  • Patent number: 4236015
    Abstract: A 1-(2-acylaminophenyl)imidazole of formula: ##STR1## wherein R.sup.5 is a cycloaliphatic, phenyl, substituted phenyl group bonded to the carbonyl carbon through a carbon-to-carbon linkage are intermediates for the preparation of 4-substituted imidazo[1,2-a]quinoxalines having anti-inflammatory, immunosuppressant and anti-fungal activity.
    Type: Grant
    Filed: May 7, 1979
    Date of Patent: November 25, 1980
    Assignee: Westwood Pharmaceuticals, Inc.
    Inventors: Paul L. Warner, Jr., Edward J. Luber, Jr.
  • Patent number: 4229452
    Abstract: A method for treating inflammatory disorders in mammals which comprises administering to said mammals having an inflammatory disorder a therapeutically effective amount of 4-trifluoromethylimidazo[1,2-a]quinoxaline.
    Type: Grant
    Filed: July 12, 1979
    Date of Patent: October 21, 1980
    Assignee: Westwood Pharmaceuticals, Inc.
    Inventors: Paul L. Warner, Jr., Edward J. Luber, Jr.
  • Patent number: 4229432
    Abstract: An antiperspirant stick composition in which the antiperspirant material is maintained substantially homogeneously distributed throughout the stick by virtue of the presence of certain waxy materials.
    Type: Grant
    Filed: April 19, 1978
    Date of Patent: October 21, 1980
    Assignee: Bristol-Myers Company
    Inventor: Navin Geria
  • Patent number: 4225724
    Abstract: 2(1-imidazolyl)phenylureylene compounds of the formula: ##STR1## wherein R.sup.2 is hydrogen or a radical bonded to the nitrogen by a carbon to nitrogen linkage and selected from the group consisting of aliphatic, cycloaliphatic, phenyl, substituted phenyl, fused bicyclic aryl, and monocyclic aryl substituted aliphatic groups are intermediates for the preparation of 4-substituted amino imidazo[1,2-a]quinoxalines having immunosuppressant activity.
    Type: Grant
    Filed: March 5, 1979
    Date of Patent: September 30, 1980
    Assignee: Westwood Pharmaceuticals, Inc.
    Inventors: Paul L. Warner, Jr., Edward J. Luber, Jr.
  • Patent number: 4200750
    Abstract: A 4-substituted imidazo [1,2-a]quinoxaline of formula: ##STR1## or a pharmaceutically acceptable salt thereof wherein R.sup.1 is bonded to a ring carbon through a carbon-to-carbon linkage and is an aliphatic, cycloaliphatic, substituted phenyl, fused bicyclic aryl; or a monocyclic aryl substituted aliphatic group.
    Type: Grant
    Filed: December 8, 1977
    Date of Patent: April 29, 1980
    Assignee: Westwood Pharmaceuticals Inc.
    Inventors: Paul L. Warner, Jr., Edward J. Luber, Jr.
  • Patent number: 4198508
    Abstract: Preparation of 4-substituted imidazo[1,2-a]quinoxalines by cyclizing a compound of the formula: ##STR1## with phosphorous oxychloride wherein X.sup.2 is a group --R.sup.5 or --NHR.sup.2 where R.sup.5 and R.sup.2 are hydrogen or various organo groups.
    Type: Grant
    Filed: December 8, 1977
    Date of Patent: April 15, 1980
    Assignee: Westwood Pharmaceuticals Inc.
    Inventors: Paul L. Warner, Jr., Edward J. Luber, Jr.
  • Patent number: 4197403
    Abstract: A 4-substituted imidazo[1,2-a]quinoxaline of formula: ##STR1## or a pharmaceutically acceptable salt thereof wherein R.sup.2 is hydrogen or a radical bonded to the nitrogen by a carbon to nitrogen linkage and selected from the group consisting of aliphatic, cycloaliphatic, phenyl, substituted phenyl, fused bicyclic aryl, and monocyclic aryl substituted aliphatic group.
    Type: Grant
    Filed: December 8, 1977
    Date of Patent: April 8, 1980
    Assignee: Westwood Pharmaceuticals Inc.
    Inventors: Paul L. Warner, Jr., Edward J. Luber, Jr.
  • Patent number: 4196145
    Abstract: Oxidation dye compositions particularly useful for dyeing human hair containing as the meta component compounds of the formula: ##STR1## or their non-toxic salts, wherein R is alkyl, hydroxyalkyl, phenylalkyl, phenylsulfonyls, alkylsulfonyls or cyanoalkyl.
    Type: Grant
    Filed: January 9, 1978
    Date of Patent: April 1, 1980
    Assignee: Clairol Incorporated
    Inventors: Alexander Halasz, David Cohen
  • Patent number: 4191767
    Abstract: A method for treating a fungal infection in mammals which comprises administering to said mammals having a fungal infection a therapeutically effective amount of a 4-(substituted phenyl)imidazo[1,2-a]quinoxaline.
    Type: Grant
    Filed: December 8, 1977
    Date of Patent: March 4, 1980
    Assignee: Westwood Pharmaceuticals, Inc.
    Inventors: Paul L. Warner, Jr., Edward J. Luber, Jr.
  • Patent number: 4191766
    Abstract: A method for reducing the immunological response in mammals by the administration of certain substituted phenyl or substituted anilino imidazo[1,2-a]quinoxalines.
    Type: Grant
    Filed: December 8, 1977
    Date of Patent: March 4, 1980
    Assignee: Westwood Pharmaceuticals, Inc.
    Inventors: Paul L. Warner, Jr., Edward J. Luber, Jr.
  • Patent number: 4189066
    Abstract: A container provided with a dispensing closure comprising a cavity-containing ball rotatable in the neck of the container, a resilient retaining ring holding the ball in contact with the neck, and a locking ring thereover threadable on the neck.
    Type: Grant
    Filed: December 4, 1978
    Date of Patent: February 19, 1980
    Assignee: Bristol-Myers Company
    Inventor: Walter G. Berghahn
  • Patent number: 4177939
    Abstract: In a squeeze bottle including a container having an upstanding neck portion and a spray unit in the neck portion through which product is dispensed from the container, the improvement comprising bellowed portions in the walls of the container and a compressible shroud surrounding the container walls. The shroud is formed of two sections, which are joined by a mating groove and bead arrangement on their edges and which substantially overlap each other when a squeezing pressure is applied to the shroud and a predetermined resistance of the groove and bead arrangement is overcome, so that the shroud sections compress the bellowed container walls and product is dispensed.
    Type: Grant
    Filed: July 22, 1977
    Date of Patent: December 11, 1979
    Assignee: Bristol-Myers Company
    Inventor: Ralph H. Thomas
  • Patent number: D253394
    Type: Grant
    Filed: October 19, 1977
    Date of Patent: November 13, 1979
    Assignee: Bristol-Myers Company
    Inventors: Walter G. Berghahn, Jack Weinstein
  • Patent number: D255654
    Type: Grant
    Filed: October 11, 1977
    Date of Patent: July 1, 1980
    Assignee: Bristol-Myers Company
    Inventor: Stephen H. Goss
  • Patent number: D258199
    Type: Grant
    Filed: September 1, 1978
    Date of Patent: February 10, 1981
    Assignee: Bristol-Myers Company
    Inventor: Albert H. Torongo, Jr.
  • Patent number: D259816
    Type: Grant
    Filed: August 20, 1979
    Date of Patent: July 7, 1981
    Assignee: Clairol Incorporated
    Inventor: Larry C. Sledge