Patents Represented by Attorney Irving Holtzman
  • Patent number: 4172947
    Abstract: A 1-(2-acylaminophenyl)imidazole of formula: ##STR1## wherein R.sup.5 is hydrogen or an aliphatic, cycloaliphatic, phenyl, substituted phenyl, fused bicyclic aryl or monocyclic aryl substituted aliphatic group bonded to the carbonyl carbon through a carbon-to-carbon linkage. The compounds are useful as intermediates in the preparation of 4-substituted imidazo[1,2-a]quinoxalines.
    Type: Grant
    Filed: December 8, 1977
    Date of Patent: October 30, 1979
    Assignee: Westwood Pharmaceuticals, Inc.
    Inventors: Paul L. Warner, Jr., Edward J. Luber, Jr.
  • Patent number: 4172149
    Abstract: Treats living skin in which sebum secretion is excessive with certain triglycerides to reduce the level of sebum secretion.
    Type: Grant
    Filed: January 30, 1978
    Date of Patent: October 23, 1979
    Assignee: Westwood Pharmaceuticals, Inc.
    Inventors: Jeffrey S. Pinto, Sung L. Hsia, Paul L. Warner, Jr.
  • Patent number: 4147750
    Abstract: Prepares a wax-based applicator stick by pouring a melt of said wax-based material into a dispenser container, allowing said material to cool to a semi-solid state, inserting a tubular probe into the center of said mass, withdrawing the same to form a cavity and then flaming the mass to eliminate the cavity so formed.
    Type: Grant
    Filed: July 24, 1978
    Date of Patent: April 3, 1979
    Assignee: Bristol-Myers Company
    Inventors: Navin Geria, George Shaleesh
  • Patent number: 4135524
    Abstract: A process for treating hair to reduce its critical surface tension and/or coefficient of friction by applying to said hair a composition comprising a fluoropolymer containing as monomers at least: ##STR1## wherein n is a number of about 7 to 11 inclusive; and ##STR2## in which n' is a number of about 2 to 4 inclusive and R.sup.1 and R.sup.2 are lower alkyl, preferably having 1-4 carbon atoms or its N-oxides or salts.
    Type: Grant
    Filed: March 30, 1977
    Date of Patent: January 23, 1979
    Assignee: Clairol Incorporated
    Inventors: Ira E. Rosenberg, John A. Ferguson, Norman P. Loveless
  • Patent number: 4119399
    Abstract: A composition for coloring hair comprising a liquid vehicle, an oxidizing agent and at least one di-long chain aliphatic hydrocarbon quaternary amine compound and a method for coloring hair using this composition.
    Type: Grant
    Filed: May 11, 1977
    Date of Patent: October 10, 1978
    Assignee: Clairol Incorporated
    Inventors: Raymond Feinland, Stanley Pohl, Michael Hnatchenko
  • Patent number: 4111567
    Abstract: A liquid applicator which comprises a liquid storage container fitted with a shaped applicator means that is made of a non-flexible, non-deformable, sintered, porous synthetic plastic resin having a controlled porosity and having omni-directional interconnecting pores.
    Type: Grant
    Filed: January 13, 1977
    Date of Patent: September 5, 1978
    Assignee: Bristol-Myers Company
    Inventors: Walter G. Berghahn, Jack Weinstein
  • Patent number: 4109785
    Abstract: A child resistant package is provided which comprises a container body and removable cap. The cap is only removable by applying pressure to the underside of the cap. Access to the underside of the cap is had through a channel which is longer than the length of the finger of an average child but not longer than the length of the finger of an adult.
    Type: Grant
    Filed: November 21, 1977
    Date of Patent: August 29, 1978
    Assignee: Bristol-Myers Company
    Inventors: Walter G. Berghahn, Martha L. Berghahn
  • Patent number: 4102995
    Abstract: A tar formulation used in the treatment of skin disorders containing tar, propylene glycol, ethyl alcohol and a gelling agent e.g. Carbopol 940.
    Type: Grant
    Filed: May 13, 1976
    Date of Patent: July 25, 1978
    Assignee: Westwood Pharmaceuticals Inc.
    Inventor: Peter Hebborn
  • Patent number: 4097606
    Abstract: APAP tablet containing from about 190 to 1000 milligrams of APAP, from 25 to 100 milligrams of an alkali metal salt of a low substituted carboxymethyl starch such as sodium or potassium, and preferably sodium and, optionally, a non-toxic pharmaceutically acceptable binder in a quantity equal to or less than the amount of APAP in the tablet. Several methods are described for preparing these tablets.
    Type: Grant
    Filed: October 8, 1975
    Date of Patent: June 27, 1978
    Assignee: Bristol-Myers Company
    Inventors: Leonard Chavkin, F. Henry Merkle
  • Patent number: 4096243
    Abstract: A composition for lightening hair comprising a liquid vehicle, an oxidizing agent and at least one di-long chain aliphatic hydrocarbon quaternary amine compound and a method for lightening hair using this composition.
    Type: Grant
    Filed: February 9, 1976
    Date of Patent: June 20, 1978
    Assignee: Clairol Incorporated
    Inventors: Raymond Feinland, Stanley Pohl, Michael Hnatchenko
  • Patent number: 4092102
    Abstract: Oxidation dye compositions particularly useful for dyeing human hair containing as the meta component compounds of the formula: ##STR1## or their non-toxic salts, wherein R is alkyl, hydroxyalkyl, phenylalkyl, phenylsulfonyls, alkylsulfonyls or cyanoalkyl.
    Type: Grant
    Filed: August 20, 1976
    Date of Patent: May 30, 1978
    Assignee: Clairol Incorporated
    Inventors: Alexander Halasz, David Cohen
  • Patent number: 4087529
    Abstract: N-mono(alkoxymethyl)phenobarbitals wherein the alkoxy group has 1 to 4 carbon atoms are disclosed. The compounds are prepared by reacting the dialkali metal salt of thiophenobarbital with chloromethyl alkyl ether followed by treating the resultant N,S-bis(alkoxymethyl)thiophenobarbital with an oxidizing agent. The compounds are useful as anti-convulsant agents.
    Type: Grant
    Filed: March 24, 1977
    Date of Patent: May 2, 1978
    Assignee: Bristol-Myers Company
    Inventor: Julius A. Vida
  • Patent number: 4059688
    Abstract: Hair fixation with fluorine containing acrylate or methacrylate terpolymers or with mixtures thereof with known non-fluorine containing hair fixing polymers.
    Type: Grant
    Filed: June 29, 1976
    Date of Patent: November 22, 1977
    Assignee: Clairol Incorporated
    Inventors: Ira E. Rosenberg, John A. Ferguson, Norman P. Loveless
  • Patent number: 4054565
    Abstract: N-mono (alkoxymethyl)phenobarbitals wherein the alkoxy group has 1 to 4 carbon atoms are disclosed. The compounds are prepared by reacting the dialkali metal salt of thiophenobarbital with chloromethyl alkyl ether followed by treating the resultant N,S-bis(alkoxymethyl)thiophenobarbital with an oxidizing agent. The compounds are useful as anticonvulsant agents.
    Type: Grant
    Filed: September 24, 1975
    Date of Patent: October 18, 1977
    Assignee: Bristol-Myers Company
    Inventors: Julius A. Vida, Carlos M. Samour
  • Patent number: 4054413
    Abstract: An autoxidizable hair preparation capable of coloring hair when applied thereto and exposed to the atmosphere comprising N,N-bis(2-hydroxyethyl)-p-phenylenediamine or an acid addition salt thereof and a triol selected from the group consisting of 1,2,4-benzenetriol and 2,4,5-trihydroxytoluene. The preparation is applied at multiple spaced intervals of time until the desired color build-up is attained. Also prepares the composition by preforming a solution of the triol by storing the corresponding triacetate in acid solution for a period of time then adding the N,N-bis(2-hydroxyethyl)-p-phenylenediamine.
    Type: Grant
    Filed: April 23, 1975
    Date of Patent: October 18, 1977
    Assignee: Clairol Incorporated
    Inventors: Raymond Feinland, Sigmund Iscowitz, Milos S. Bil
  • Patent number: 4050826
    Abstract: A liquid applicator which comprises a liquid storage container fitted with a shaped applicator means that is made of a non-flexible, non-deformable, sintered, porous synthetic plastic resin having a controlled porosity and having omni-directional interconnecting pores.
    Type: Grant
    Filed: February 11, 1976
    Date of Patent: September 27, 1977
    Assignee: Bristol-Myers Company
    Inventors: Walter G. Berghahn, Jack Weinstein
  • Patent number: 4046894
    Abstract: Various derivatives of barbituric acid and of diphenylhydantoin are described in which alkoxymethyl or benzyloxymethyl groups are attached to the nitrogen atoms of the rings. Therapeutic compositions containing these compounds and their use as anticonvulsant agents are described.
    Type: Grant
    Filed: March 18, 1971
    Date of Patent: September 6, 1977
    Assignee: Bristol-Myers Company
    Inventors: Carlos M. Samour, Julius A. Vida
  • Patent number: 4029662
    Abstract: There is disclosed an improved process for the preparation of 1,3-bis(alkoxyalkyl)- and 1,3-bis(benzyloxyalkyl)-5,5-disubstituted barbituric acid derivatives, such as 1,3-bis(methoxymethyl)phenobarbital, by reacting e.g., phenobarbital, preferably, a multiple molar excess of dimethoxymethane and an at least equimolar amount of anhydrous stannic chloride based on the amount of phenobarbital.
    Type: Grant
    Filed: April 30, 1976
    Date of Patent: June 14, 1977
    Assignee: Bristol-Myers Company
    Inventor: Julius A. Vida
  • Patent number: 4021125
    Abstract: A ball type roll-on liquid dispenser provided with a generally spherical ball and relatively small supporting nibs supporting the ball for rotation. A restricted passageway is provided between the ball and neck of the container to meter the liquid contents of the container. A thin retaining ring for retaining the ball is also provided as well as a closure liner adapted to apply variable pressure to the thin retaining ring to control the flow of liquid from the container and to completely seal the container from the atmosphere.
    Type: Grant
    Filed: October 17, 1975
    Date of Patent: May 3, 1977
    Assignee: Bristol-Myers Company
    Inventors: Walter G. Berghahn, Jack Weinstein
  • Patent number: RE29653
    Abstract: The specification discloses 4-N,N-bis-(2-hydroxyethyl)aminoacylphenones which are useful as sunscreening agents for absorbing intermediate range radiation. The acyl moiety is derived from the group of alkanoic acids having from 2 to about 16 carbon atoms.
    Type: Grant
    Filed: August 16, 1976
    Date of Patent: May 30, 1978
    Assignee: Westwood Pharmaceuticals, Inc.
    Inventor: Paul L. Warner, Jr.