Abstract: Sampler apparatus and method are provided and include both closed and open tube samplers, and selector valve operable to select therebetween for sample supply to automated sample analysis apparatus. A shear valve divides the samples into separate sample quantities for independent sample quantity analysis by multi-channel sample analysis apparatus. A pressure equilibration chamber prevents vacuum build-up in the closed tube sampler to insure the supply of consistent sample quantities therefrom. A source of a pressurized rinse solution is provided; and is operatively connected to the sampler apparatus in such manner as to insure the particularly thorough rinsing and cleansing of all relevant sampler components to remove sample residue therefrom between sampling operations, thereby reducing sample carryover to levels below those of clinical significance.

Abstract: The apparatus comprise a generally tubular outer element, a generally cylindrical inner element disposed therewithin and sized relative thereto to provide a generally annular operating space therebetween. An intermediate element is disposed in said operating space and is dimensioned relative thereto to create interference fits with said outer and inner elements and prevent relative movement therebetween. Means are provided to introduce pressurized fluid to the respective element interfaces to expand the outer element within the elastic limit thereof to an extent sufficient to release the interference fits and enable relative outer-inner element movement. Re-locking of the outer and inner elements occurs automatically upon depressurization of the fluid and attendant return of the outer element to its unexpanded configuration. Actuating means to effect relative outer and inner element movement upon apparatus unlocking are also provided, and include means to pressurize the fluid.

Abstract: Dual liquid dispenser package is provided and is operable to supply liquids from liquid supply chambers to liquid reservoirs through liquid supply channels by centrifugal force-induced liquid displacement and flow attendant dispenser package rotation. The supply channels include means to greatly inhibit, if not totally prevent, liquid foaming attendant liquid flow from the supply chambers to the reservoirs. Vents are included to vent the liquid supply chambers to atmosphere to prevent vacuum build-up therein, and include means preventing spillage of the liquids from the dispenser package through the vents. The dispenser package is particularly adapted for use in the supply of two reagent liquids to automated sample liquid analysis systems.

Abstract: Apparatus and method are provided for the exchange of substances between substance carrier and recovery fluids in predetermined carrier/recovery fluid volumetric ratios, and operate through the vaporization of the carrier fluid in a separation chamber to separate the substance therefrom at a separation zone therein and effect the deposition and accumulation of the substance in a relatively narrow band, and the subsequent recovery of the substance band form the separation chamber by the substance recovery fluid. Correlation of the carrier fluid flow rate into the separation chamber, and the separation chamber temperature, is effective to determine the location of the substance band in the separation chamber. Segmentation of the substance carrier and recovery fluids materially increases the efficiency of the separation and recovery processes. The apparatus and method are particularly adapted for high operational rate operation on an automated basis; and are adapted for operation on a batch basis.

Abstract: New and improved microsample cup is provided, and comprises an outer cup body member, and an inner sample liquid vessel disposed and supported therewithin. An integral sample liquid overflow reservoir is provided to surround the inner sample liquid vessel to facilitate the precise filling of the same to a predetermined level coincident with the maximum sample liquid capacity thereof by enabling the overflow from the sample liquid vessel of any sample liquid in excess of the maximum sample liquid vessel capacity into the sample liquid overflow reservoir.

Abstract: Sampler apparatus and method are provided and include both closed and open tube samplers, and selector valve operable to select therebetween for sample supply to automated sample analysis apparatus. A shear valve divides the samples into separate sample quantities for independent sample quantity analysis by multi-channel sample analysis apparatus. A pressure equilibration chamber prevents vacuum bulid-up in the closed tube sampler to insure the supply of consistent sample quantities therefrom. A source of a pressurized rinse solution is provided; and is operatively connected to the sampler apparatus in such manner as to insure the particularly thorough rinsing and cleansing of all relevant sample components to remove sample residue therefrom between sampling operations, thereby reducing sample carryover to levels below those of clinical significance.

Abstract: Apparatus and method are provided for the exchange of substances between substance carrier and recovery fluids in predetermined carrier/recovery fluid volumetric ratios, and operate through the vaporization of the carrier fluid in a separation chamber to separate the substance therefrom at a separation zone therein and effect the deposition and accumulation of the substance in a relatively narrow band, and the subsequent recovery of the substance band from the separation chamber by the substance recovery fluid. Correlation of the carrier fluid flow rate into the separation chamber, and the separation chamber temperature, is effective to determine the location of the substance band in the separation chamber. Segmentation of the substance carrier and recovery fluids materially increases the efficiency of the separation and recovery processes. The apparatus and method are particularly adapted for high operational rate operation on an automated basis; and are adapted for operation on a batch basis.

Abstract: Apparatus and method are provided for the precisely controlled and coordinated supply of sample and sheath stream fluids to a sheath stream flow cell, and comprise the use of positive displacement differential pumping means which are operable to insure consistent sample and sheath stream fluid diameters, velocity and volume flow conditions within the flow cell, thereby maximizing the accuracy and reproducibility of successive analyses.

Abstract: An apparatus and method are provided for the precisely controlled and coordinated, concomitant supply at optimal flow rates, by differential pumping, of selected sample and sheath liquids from respective pluralities of different sources thereof, to the same sheath stream flow cell for successive different types of sample analyses, thereby maximizing sample analysis accuracy and reproducibility, and reducing apparatus complexity and costs. The apparatus and method are particularly useful in high-speed automated biomedical analytical systems.

Abstract: A new and improved isolation liquid layer retention device is provided, and comprises a porous member operatively associated with the interior of a container which contains a quantity of an aqueous liquid having a layer of a generally immiscible isolation liquid which is generally of greater density disposed thereon. The porous member is operable to cause the aqueous liquid to form a generally convex meniscus to strongly support the generally denser isolation liquid layer thereon to prevent the sinking of the isolation liquid into the aqueous liquid; and is operable to act as a moderating control by virtue of a "source and sink" action vis-a-vis the isolation liquid to maintain a uniform and readily reproducible configuration for the isolation liquid layer on a container-to-container basis with regard to each of a plurality of the containers. The device is particularly adapted for use with a plurality of containers of aqueous sample and reagent liquids in contemporary automated sample liquid analysis systems.

Abstract: New and improved connector is provided for the zero dead volume connection of separate, like diameter flexible tubing lengths by direct tubing length end abutment and connection under controlled conditions. The connector is particularly adapted for use with tubing lengths of fluorocarbon or like materials in contemporary biomedical sample liquid analysis systems which utilize an immiscible isolation liquid or "oil" to minimize sample liquid carryover and maximize the accuracy of sample liquid analysis results.

Abstract: A lens for utilization in the radiation energy exit port of a radiation energy integrating sphere is provided, and functions to prevent instrumental specular radiation energy reflections from striking the interior wall surfaces of the sphere and being collected thereby. The instrumental specular radiation energy reflections include those from the lens, per se, and those from instrumentation disposed without the integrating sphere.

Abstract: A board game is provided and includes a checker-like game board having a plurality of rows of differently colored playing spaces. Differently colored playing pieces, both of a single color, and two colors, are positionable on the playing spaces in accordance with playing space-playing piece color coincidence. For adult play, movement of the playing pieces to like-colored playing spaces on the opponent's side of the game board is accomplished by playing piece movement, and jumping of the opponent's playing pieces; with the single colored playing pieces having greater freedom of movement in the manner of "kings" in checkers. For play by children, movement of the playing pieces to like-colored playing spaces on the opponent's side of the game board is accomplished by playing piece movement in accordance with sequential "throws" of multi-colored cubes.

Abstract: Security gate apparatus for securing building openings in the nature of window and door openings are disclosed; and comprise a security gate including gate-carried locking means which, while of particularly sturdy construction and effective to render it extremely difficult if not impossible as a practical matter to open the security gate from without the building opening, are nonetheless virtually foolproof in operation, and which are very readily and conveniently openable from within the building, even by those of somewhat limited mental and/or physical capacities, in readily apparent manner to thereby insure virtually immediate exit from the building through the building opening for the building occupants in emergency situations.

Abstract: New and improved, mechanically self-resonant apparatus and method for the non-invasive mixing of materials are disclosed, and comprise vibrator means including container means for the materials to be mixed, and drive means to drivingly vibrate the vibrator means. Sensor means are operatively associated with the vibrator means and the drive means, and are operable to sense the frequency of vibration of the vibrator means and maintain that frequency at or near the resonant frequency of the vibrator means. This promotes thorough mixing of the materials, and minimizes the energy input required for vibrational mixing of the materials. Control means are provided to control the amplitude of vibration of the vibrator means at or near the resonant frequency to avoid damage to the materials attendant mixing. The container means may take the form of a conduit through which the materials to be mixed are flowing attendant vibrational mixing.

Abstract: New and improved, liquid level adjusting and filtering device is provided, and is operable upon insertion into a container to automatically adjust the level of a liquid as contained in the container to a predetermined, precisely repeatable location, and to filter the thusly level-adjusted liquid. The device is particularly adapted for use in conjunction with test tube-like devices, in the nature of those marketed under the Trademark "Vacutainer" by the Becton-Dickinson Company of East Rutherford, NJ, containing whole blood samples which have been separated as by centrifugation into respective blood cell, buffy and blood serum layers; and is operable in that context to present blood serum samples to automated sample analysis systems at the same predetermined and precisely repeatable location relative to the aspirating probe means of such systems.

Abstract: Automatic skin packaging apparatus are provided and comprise concomitantly operable substrate feeder means, film heater means, film pressure forming means, film cooling means, film and substrate die cutting means, and skin packaged article-substrate finishing and collection means. Conveyor and film supply means are intermittently operable, from constantly operable drive motor means, to intermittently advance article-bearing substrates to the above specified components, in turn, and to intermittently supply film thereover at said film heater means. Stop means insure precise conveyor means operation, and interrelated control means are provided to precisely control the time and duration of operation of all apparatus components.

Abstract: The apparatus comprise a generally tubular outer element, a generally cylindrical inner element disposed therewithin and sized relative thereto to provide a generally annular operating space therebetween. An intermediate element is disposed in said operating space and is dimensioned relative thereto to create interference fits with said outer and inner elements and prevent relative movement therebetween. Means are provided to introduce pressurized fluid to the respective element interfaces to expand the outer element wherein the elastic limit thereof to an extent sufficient to release the interference fits and enable relative outer-inner element movement. Re-locking of the outer and inner elements occur automatically upon depressurization of the fluid and attendant return of the outer element to its unexpanded configuration. Actuating means to effect relative outer and inner element movement upon apparatus unlocking are also provided, and include means to pressurize the fluid.

Abstract: New and improved ram drive chuck is provided and comprises workpiece driving means which are moveable between an extended position thereof relative to an appropriately positioned workpiece wherein the workpiece driving means are operable to drivingly engage, support and rotate the workpiece, and a retracted workpiece driving means position relative to the appropriately positioned workpiece wherein the workpiece driving means are disengaged from the workpiece. Means to positively disengage the workpiece driving means from the workpiece upon movement of the former into the retracted position thereof are operable attendant the drive of a specified form of workpiece.

Abstract: A new and improved preparation for the care and conditioning of the feet is provided and comprises magnesium sulphate, natural sea and land salts, a papaya enzyme and salicylic acid which, when mixed to form a powder and dissolved in warm or hot water, provides a soothing and comforting soak for the feet, and one which is particularly conducive to the subsequent removal of dead tissue in the nature of callouses and the like therefrom through softening of that dead tissue.