Patents Represented by Attorney Jill H. Krafte

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  • Adsorption of proteins from fluids
    Patent number: 4684530
    Abstract: Protein may be removed from fluids by adsorption onto inorganic oxide-silica cogels. Preferred cogels are silica alumina and silica magnesia activated so that the cogel surface is in acid form, with H.sub.0 values less than the pH of the protein-containing fluid which, in turn, is less than the isoelectric point of the protein. The method is particularly effective for removing haze-forming proteins from wine.
    Type: Grant
    Filed: October 4, 1985
    Date of Patent: August 4, 1987
    Assignee: W. R. Grace & Co.
    Inventors: William A. Welsh, Yves O. Parent, Stanley A. Mertz
  • Method for refining glyceride oils using amorphous silica
    Patent number: 4629588
    Abstract: Adsorbents comprising amorphous silicas with effective average pore diameters of about 60 to about 5000 Angstroms are useful in processes for the removal of trace contaminants, specifically phospholipids and associated metal ions, from glyceride oils.
    Type: Grant
    Filed: December 7, 1984
    Date of Patent: December 16, 1986
    Assignee: W. R. Grace & Co.
    Inventors: William A. Welsh, Yves O. Parent
  • Scale inhibiting composition
    Patent number: 4609483
    Abstract: A composition for inhibiting deposition of scale in aqueous systems is disclosed which comprises carboxymethylcellulose and gluconic acid or glucoheptonic acid or both, or their water soluble salts. The composition is incorporated in the aqueous system in concentrations sufficient to substantially completely prevent scale deposition.
    Type: Grant
    Filed: March 7, 1985
    Date of Patent: September 2, 1986
    Assignee: W. R. Grace & Co.
    Inventors: Dionisio G. Cuisia, Chih M. Hwa
  • Purification of L-phenylalanine
    Patent number: 4584399
    Abstract: A process is disclosed for the separation and recovery of L-phenylalanine from an impure aqueous solution by ultrafiltering and/or centrifuging to remove cellular material and large proteins, contacting the filtered solution with activated carbon to adsorb L-phenylalanine, eluting adsorbed L-phenylalanine, passing the eluate through an ion exchanger, and recovering substantially pure L-phenylalanine from the ion exchange eluate.
    Type: Grant
    Filed: November 27, 1984
    Date of Patent: April 22, 1986
    Assignee: W. R. Grace & Co.
    Inventors: Charles Portal, James F. Walter
  • Process for preparing L-aspartic acid
    Patent number: 4560653
    Abstract: A process for preparing L-aspartic acid by contacting fumarate ion-containing solution with aspartase or aspartase-producing microorganisms, adding maleic acid to insolubilize or precipitate the L-aspartic acid, isomerizing maleic acid in the supernatant liquid to form fumaric acid and recycling the fumaric acid into contact with the enzyme or microorganisms.
    Type: Grant
    Filed: June 6, 1983
    Date of Patent: December 24, 1985
    Assignee: W. R. Grace & Co.
    Inventors: Martin B. Sherwin, John J. Blouin
  • Carbon monoxide process for the production of alpha amino acids
    Patent number: 4547590
    Abstract: A process is disclosed for the synthesis of alpha-amino acid by first contacting the condensation product of an aldehyde or ketone and an amine or amide with a protic or Lewis acid solvent and carbon monoxide to form an intermediate reaction product, and then hydrolyzing the intermediate to yield a product comprising the alpha-amino acid. The reaction rate and product yield can be increased by the addition of a Group 1B metal oxide catalyst in the first step.
    Type: Grant
    Filed: July 6, 1984
    Date of Patent: October 15, 1985
    Assignee: W. R. Grace & Co.
    Inventors: Richard A. Love, Lee R. Zehner
  • Microorganism strains for the fermentative preparation of L-serine
    Patent number: 4528273
    Abstract: A method for improving a strain of microorganisms capable of converting glycine to L-serine by selecting for strain-improving mutations such that the improved strain is serine dehydratase negative and is resistant to at least one of the amino acid analogs serine hydroxamate, glycine hydroxamate or methionine hydroxamate.
    Type: Grant
    Filed: November 22, 1983
    Date of Patent: July 9, 1985
    Assignee: W. R. Grace & Co.
    Inventors: Gerald G. Lovinger, Susan A. Whitehead
  • Fermentative preparation of L-leucine
    Patent number: 4421854
    Abstract: L-leucine is prepared by cultivation of an analogue-resistant mutant of Arthrobacter citreus in an aqueous nutrient medium under aerobic conditions. The cultivation is preferably carried out at about 30.degree. C. and at a pH of 5 to 0.8. L-leucine is recovered from the fermentation broth. In a preferred embodiment the mutant is further mutated, and the second mutant is similarly fermented to prepare L-leucine.
    Type: Grant
    Filed: June 16, 1982
    Date of Patent: December 20, 1983
    Assignee: W. R. Grace & Co.
    Inventors: Mark H. Updike, Gary J. Calton
  • Fermentative preparation of L-leucine
    Patent number: 4421853
    Abstract: L-leucine is prepared by cultivation of an analogue-resistant mutant of Brevibacterium thiogenitalis in an aqueous nutrient medium under aerobic conditions. The cultivation is preferably carried out at about 30.degree. C. and at a pH of 5 to 8. L-leucine is recovered from the fermentation broth.
    Type: Grant
    Filed: June 16, 1982
    Date of Patent: December 20, 1983
    Assignee: W. R. Grace & Co.
    Inventors: Mark H. Updike, Gary J. Calton
  • Apple juice clarification by using silica hydrogels
    Patent number: H89
    Abstract: A process for removing turbidity from apple juices is disclosed; said process comprising treatment of said juices with silica hydrogel and filtering through a diatomaceous earth filtering medium.
    Type: Grant
    Filed: August 20, 1985
    Date of Patent: July 1, 1986
    Assignee: W. R. Grace & Co.
    Inventors: Cathy L. Harville, Thomas E. Williams