Patents Represented by Attorney Joan Thierstein
  • Patent number: 5559080
    Abstract: Disclosed are certain 3-phenoxypyridazines, compositions thereof which are herbicidal and methods of using such compositions for controlling undesired plants. Intermediate compounds useful in preparing the phenoxypyridazines are also disclosed.
    Type: Grant
    Filed: October 11, 1994
    Date of Patent: September 24, 1996
    Assignee: Monsanto Company
    Inventors: Michael S. South, Michael J. Miller
  • Patent number: 5554617
    Abstract: A method for altering the immunoregulatory system of humans and animals by administering a compound of the formula: ##STR1## wherein X.sub.3 is equal to X, X.sub.4, or X.sub.5 wherein X.sub.4 is fluoro, chloro, bromo or iodo, and X.sub.5 is mono-, di- or trihalomethyl, mono-, di or trifluoroethyl, perfluoropropyl, and wherein X is alkyl of from 1 to 3 carbon atoms, inclusive, 2-propynyl and 2-propenyl, and X.sub.1 is as defined in the specification.
    Type: Grant
    Filed: April 7, 1995
    Date of Patent: September 10, 1996
    Assignee: The Upjohn Company
    Inventors: Dale A. Stringfellow, Patricia E. Fast
  • Patent number: 5514717
    Abstract: Novel 3,4,4-trifluorobutenoic acid derivatives of the formula ##STR1## wherein Q is --(C.dbd.W)--R.sub.2 wherein W is O or S, and R.sub.2 is an aliphatic or aromatic group when W.dbd.O; --OR.sub.50 ; --SR.sub.50 ; or --NR.sub.50 R.sub.60 wherein R.sub.60 is hydrogen or R.sub.50 ; NR.sub.7 R.sub.8 ; a heterocyclic group; phenyl substituted by alkyl; or any agronomically acceptable salt thereof having usefulness as nematocides, insecticides and acaricides.
    Type: Grant
    Filed: October 26, 1994
    Date of Patent: May 7, 1996
    Assignee: Monsanto Company
    Inventors: Dennis P. Phillion, Gopichand Yalamanchili, Peter G. Ruminski
  • Patent number: 5498624
    Abstract: Novel azolyl derivatives, ie 2'-(substituted)cycloalkyl carboxanilides, useful as fungicides, methods of using said compounds and mixtures containing them.
    Type: Grant
    Filed: May 3, 1995
    Date of Patent: March 12, 1996
    Assignee: Monsanto Company
    Inventors: Jim I. McLoughlin, Deborah A. Mischke, Marla J. Williams, Suzanne Metz
  • Patent number: 5498630
    Abstract: A method of controlling Take-All disease of plants by applying a fungicide of the formula ##STR1## wherein Z1 and Z2 are C and are part of an aromatic ring which is benzothiophene; andA is selected from --C(X)-amine wherein the amine is an unsubstituted, monosubstituted or disubstituted amino radical, --C(O)--SR.sub.3, --NH--C(X)R.sub.4, and --C(.dbd.NR.sub.3)--XR.sub.7 ;B is --W.sub.m --Q(R.sub.2).sub.3 or selected from O-tolyl, 1-naphthyl, 2-naphthyl, and 9-phenanthryl, each optionally substituted with halogen or R.sub.4 ;Q is C, Si, Ge, or Sn;W is --C(R.sub.3).sub.p H.sub.(2-p) --; or when Q is C, W is selected from --C(R.sub.3).sub.p H(.sub.2-p), --N(R.sub.3).sub.m H(.sub.1-m)--, --S(O)p--, and --O--;X is 0 or S;n is 0, 1, 2, or 3;m is 0 or 1;p is 0, 1, or 2;each R and R.sub.2 is independently defined herein;R.sub.3 is C.sub.1 -C.sub.4 alkyl;R.sub.4 is C.sub.1 -C.sub.4 alkyl, haloalkyl, alkoxy, alkylthio, alkylamino, or dialkylamino; andR.sub.7 is C.sub.1 -C.sub.
    Type: Grant
    Filed: November 16, 1994
    Date of Patent: March 12, 1996
    Assignee: Monsanto Company
    Inventors: Dennis P. Phillion, Diane S. Braccolino, Matthew J. Graneto, Wendell G. Phillips, Karey A. Van Sant, Daniel M. Walker, Sai C. Wong
  • Patent number: 5496956
    Abstract: The invention herein relates to certain substituted-arylpyrazole compounds, herbicidal compositions containing same, herbicidal methods of use and processes for preparing said compounds.
    Type: Grant
    Filed: April 4, 1995
    Date of Patent: March 5, 1996
    Assignee: Monsanto Company
    Inventors: Scott S. Woodard, Bruce C. Hamper, Kurt Moedritzer, Michael D. Rogers, Deborah A. Mischke, Gerard A. Dutra
  • Patent number: 5489571
    Abstract: The invention herein relates to certain substituted-arylpyrazole compounds, herbicidal compositions containing same, herbicidal methods of use and processes for preparing said compounds.
    Type: Grant
    Filed: November 2, 1993
    Date of Patent: February 6, 1996
    Assignee: Monsanto Company
    Inventors: Scott S. Woodard, Bruce C. Hamper, Kurt Moedritzer, Michael D. Rogers, Deborah A. Mischke, Gerard A. Dutra
  • Patent number: 5486621
    Abstract: This invention relates to 4,5-dimethyl-N-2-propenyl-2-(trimethylsilyl)-3-thiophenecarboxamide, a method for the control of Take-All disease (Gaeumannomyces species) in plants by the use of this compound, and to fungicidal compostions for carrying out the method.
    Type: Grant
    Filed: December 15, 1994
    Date of Patent: January 23, 1996
    Assignee: Monsanto Company
    Inventors: Dennis Phillion, Sai C. Wong, Barry Shortt
  • Patent number: 5484761
    Abstract: Disclosed are certain 5-methoxypyridinyloxypyridazines, compositions thereof which are herbicidal and methods of using such compositions for controlling undesired plants.Intermediates useful in preparing the pyridinyloxypyridazines are also disclosed.
    Type: Grant
    Filed: October 11, 1994
    Date of Patent: January 16, 1996
    Assignee: Monsanto Company
    Inventor: Michael S. South
  • Patent number: 5482974
    Abstract: A compound for controlling Take-all disease of plants by applying, preferably to the seed prior to planting, a fungicide of the formula ##STR1## wherein R.sup.2 is ethyl, iso-propyl, propyl or allyl; A is N(CH.sub.3).sub.1-n H.sub.n R.sup.5 or OR.sup.6 wherein n is 0 or 1, R.sup.5 is (CH.sub.3).sub.m (CH.sub.3 CH.sub.2).sub.3-m C, 1-methylcyclopentyl, 1-methylcyclohexyl or 2,3-dimethyl-2-butyl wherein m is 0, 1, 2 or 3 and R.sup.6 is independently R.sup.5 or 2,3,3-trimethyl-2-butyl;R.sup.3 is H or independently R.sup.4 ; andR.sup.4 is halo or CH.sub.3 ;with the proviso that when A is N(CH.sub.3).sub.1-n H.sub.n R.sup.5, if R.sup.3 is H and R.sup.5 is 1-methyl-1-cyclohexyl or (CH.sub.3).sub.m (CH.sub.2 CH.sub.3).sub.3-m C, where m is 0 or 3, or if R.sup.3 is halo and R.sup.5 is (CH.sub.3).sub.m (CH.sub.3 CH.sub.2).sub.3-m C, where m is 3, then R.sup.2 cannot be ethyl;and with the proviso that when A is OR.sup.6 then m is equal to or less than 2, and if R.sup.3 is H or halo and R.sup.
    Type: Grant
    Filed: March 8, 1994
    Date of Patent: January 9, 1996
    Assignee: Monsanto Company
    Inventors: Dennis P. Phillion, Karey A. Van Sant, Daniel M. Walker
  • Patent number: 5474767
    Abstract: Cross-linked controlled density polyamines which are water-insoluble and swell at pH values up to about 8 are shown. These polyamines are useful in site-specific drug delivery systems.
    Type: Grant
    Filed: January 15, 1993
    Date of Patent: December 12, 1995
    Assignee: Monsanto Company
    Inventor: Samuel J. Tremont
  • Patent number: 5473092
    Abstract: The present invention relates to catalytic asymmetric hydrogenation of phosphorus analogs of itaconic acid to synthesize novel optically active phosphono succinates.
    Type: Grant
    Filed: March 1, 1995
    Date of Patent: December 5, 1995
    Assignee: Monsanto Company
    Inventor: John J. Talley
  • Patent number: 5457134
    Abstract: Fluorinated alkene compounds useful for and methods of controlling nematodes, insects, and acarids that prey on agricultural crops. Polar compounds, for example, 3,4,4-trifluoro-3-butene-1-amine or 3,4,4-trifluoro-3-butenoic acid, are particularly useful for systemic control of pests. Novel method and intermediates for the preparation of 3,4,4-trifluoro-3-butene-1-amine are also provided.
    Type: Grant
    Filed: October 12, 1994
    Date of Patent: October 10, 1995
    Assignee: Monsanto Company
    Inventor: Peter G. Ruminski
  • Patent number: 5434157
    Abstract: 6-Aryl pyrimidinol compounds, also can be named 6-aryl pyrimidinone or 6-aryl-isocytosine novel compounds, also novel and old compounds useful for treating viral infections and inducing interferon production. Dosage forms and method of treatment are disclosed.
    Type: Grant
    Filed: January 21, 1993
    Date of Patent: July 18, 1995
    Assignee: The Upjohn Company
    Inventors: Wendell Wierenga, Harvey I. Skulnick, Dale A. Stringfellow
  • Patent number: 5389680
    Abstract: Fluorinated alkene compounds useful for and methods of controlling nematodes, insects, and acarids that prey on agricultural crops. Polar compounds, for example, 3,4,4-trifluoro-3-butene-1-amine or 3,4,4-trifluoro-3-butenoic acid, are particularly useful for systemic control of pests. Novel method and intermediates for the preparation of 3,4,4-trifluoro-3-butene-1-amine are also provided.
    Type: Grant
    Filed: October 18, 1993
    Date of Patent: February 14, 1995
    Assignee: Monsanto Company
    Inventor: Peter G. Ruminski
  • Patent number: 5380738
    Abstract: 2-Substituted-4-(4-fluorophenyl)-5-(4-(methylsulfonyl)phenyl)oxazoles or 2-substituted-5-(4-fluorophenyl)-4-(4-(methylsulfonyl)phenyl)oxazoles and derivatives thereof are found to posses significant antiinflammatory activity, especially useful for the treatment of arthritis without deleterious side effects.
    Type: Grant
    Filed: May 21, 1993
    Date of Patent: January 10, 1995
    Assignee: Monsanto Company
    Inventors: Bryan H. Norman, Len F. Lee, Jaime L. Masferrer, John J. Talley
  • Patent number: 5321153
    Abstract: This invention is selected novel chiral (essentially pure) alpha-amino phosphonates, process for the preparation which is a catalytic asymmetric hydrogenation of olefins and novel intermediates therefor. The alpha-amino phosphonates are useful as antibiotics and/or as intermediates in the preparation of phosphorus-containing analogs of peptides, i.e., phosphonopeptides or pseudopeptides having known uses, such as in antibiotics, antibiotic enhancers, or enzyme inhibitors.
    Type: Grant
    Filed: June 15, 1992
    Date of Patent: June 14, 1994
    Assignee: Monsanto Company
    Inventor: John J. Talley
  • Patent number: 5298479
    Abstract: The present invention provides novel herbicidal pyridines characterized by having in the 3- or 5-position an aliphatic or aromatic 1-ketone.
    Type: Grant
    Filed: May 17, 1993
    Date of Patent: March 29, 1994
    Assignee: Monsanto Company
    Inventors: Len F. Lee, Yuen-Lung L. Sing, Sai C. Wong
  • Patent number: 5284974
    Abstract: An improved process for the reaction of acetonitrile and hydrogen sulfide to produce thioacetamide, wherein a polymer-supported amine catalyst is used. Examples of the polymer-supported amine catalyst are polymeric dimethylaminopyridine resins, poly(4-vinylpyridine) cross-linked with divinylbenzene, and cross-linked polymer-supported 4-(N-benzyl-N-methylamino)pyridine.
    Type: Grant
    Filed: August 11, 1992
    Date of Patent: February 8, 1994
    Assignee: Monsanto Company
    Inventor: Eric L. Williams
  • Patent number: 5256680
    Abstract: The present invention is novel compounds which are 3,5-di-tertiary-butyl-4-hydroxyphenyl substituted 1,2,4- and 1,3,4-thiadazoles and oxadiazoles, and 1,2,4-triazoles, and pharmaceutically acceptable additions and base salts thereof, pharmaceutical compositions and methods of use therefor. The invention compounds are now found to have activity as inhibitors of 5-lipoxygenase and/or cyclooxygenase providing treatment of conditions advantageously affected by such inhibition including inflammation, arthritis, pain, fever, and the like.
    Type: Grant
    Filed: June 29, 1992
    Date of Patent: October 26, 1993
    Assignee: Warner-Lambert Company
    Inventors: David T. Connor, Daniel L. Flynn, Catherine R. Kostlan, Michael D. Mullican, Gary P. Shrum, Paul C. Unangst, Michael W. Wilson