Abstract: Multiple component polymer compositions for fabrication into articles. In particular, polymeric compositions comprising a heat resistant polymer; a radio frequency (“RF”) susceptible polymer; and a compatibilizing polymer.

Abstract: A multilayered film (220) suitable for medical uses is coextruded in a machine direction and comprises a first layer (222) defining a pair of peripheral edges (225,227) extending in a direction parallel to the machine direction. The film has a second layer (224) adhered to the first layer (222). The second layer (224) is positioned within the peripheral edges (225,227) defining a stripe (223).

Abstract: The present invention provides a multiple layer structure (10) for fabricating medical products. The layer structure (10) has a core layer (14) of an ethylene vinyl alcohol copolymer having an ethylene content of about 25-45 mole percent, a solution contact layer of a polyolefin positioned on a first side of the core layer, an outer layer (12) positioned on a second side of the core layer opposite the solution contact layer (16), the outer layer (12) being selected from the group consisting of polyamides, polyesters and polyolefins; two tie layers (18)—one of each adhered to the first and second sides of the core layer (14) and positioned between the solution contact layer (16) and the core layer (14) and between the outer layer (12) and the core layer (14), and wherein the structure (10) is produced in a cast coextrusion process.

Abstract: The present invention provides a method for using medical tubing for infusing therapeutic fluids to a patient comprising the steps of: providing a medical tubing having a sidewall of a polymeric blend, the blend having a polymeric material in an amount by weight within the range of 99.999%-90.0%, and an additive in an amount by weight within the range of 0.001%-10%, the tubing having been oriented along a longitudinal axis of the tubing to define a oriented diameter that is less than a diameter of the tubing before orienting; and providing fluid under pressure through the tubing to the patient.

Abstract: A protein-compatible polymer blend made from a water-soluble polymer and a matrix polymer. The glass transition temperature of either the water-soluble polymer or the matrix polymer is greater than the application temperature, i.e., the temperature at which the protein-compatible polymer blend is being used.

Abstract: A steam sterilizable monolayer medical tubing comprising a blend of a melt strength enhancing agent of a homopolymer or copolymer of polypropylene having free-end long chain branches of propylene units, a melt flow index of greater than 10 and in an amount of 1-10% by weight and a second component selected from the group of (i) a selectively hydrogenated block copolymer of a vinyl aromatic hydrocarbon and a conjugated diene and (ii) a selectively hydrogenated block copolymer of a vinyl aromatic hydrocarbon and a conjugated diene to which has been grafted, an alpha, beta-olenfically unsaturated monocarboxylic or dicarboxylic acid reagent.

Abstract: The present invention provides a medical device of a polymer composition. The composition has a first component obtained by copolymerizing a norbornene monomer and an ethylene monomer, the first component being in an amount from about 1-99% by weight of the composition; and a second component of an ethylene and &agr;-olefin copolymer, the &agr;-olefin having 6 carbons, the second component being in an amount from about 99% to about 1% by weight of the composition.

Abstract: A multi-layer, flexible, gas-permeable film (10) suitable for forming a cell culture container (20), the film (10) comprising a first layer (12) composed of a polystyrene having a thickness within the range of 0.0001 inches to about 0.0010 inches and, a second layer (14) adhered to the first layer (12) composed of a polyolefin having a thickness within the range of 0.004 inches to about 0.015 inches.

Abstract: A multiple layer structure comprising a skin layer composed of a polypropylene copolymer with styrene ethylene-butene styrene block copolymer within a range of 0-20% by weight skin layer, and, a radio frequency (“RF”) susceptible layer adhered to the skin layer. The RF layer has a first component of a propylene based polymer, a second component of a nonpropylene polyolefin, a third component of a radio frequency susceptible polymer, and a fourth component of a polymeric compatibilizing agent wherein the radio frequency susceptible polymer is selected from the group consisting of ethylene acrylic acid copolymers, ethylene methacrylic acid copolymers, polyimides, polyurethanes, polyesters, and polyureas.

Abstract: The present invention provides a polymer composition having a first component obtained by copolymerizing a norbornene monomer and an ethylene monomer, the first component being in an amount from about 1-99% by weight of the composition; and a second component of an ethylene and &agr;-olefin copolymer, the &agr;-olefin having 6 carbons, the second component being in an amount from about 99% to about 1% by weight of the composition.

Abstract: The present invention provides a reference electrode solution containing ammonium salts and phosphonium salts for the potentiometric measurement of pH and method of using the same. The use of the ammonium salts and the phosphonium salts to replace potassium chloride or sodium chloride as reference electrolytes in a standard reference electrode minimizes the formation of precipitates in sample solutions containing cation-sensitive compounds. Disruption of ion flow through the reference electrode is eliminated, and accurate pH measurements may be obtained in solutions that contain compounds having a strong affinity for hard cations.

Abstract: The present invention provides a premixed form of a buffered piperacillin product having a near neutral pH and capable of a shelf life of at least nine months, with freezer storage (−20° C. or lower), or a refrigerated shelf life of up to 14 days at about 5° C. The piperacillin may additionally contain a tazobactam component to inactivate beta-lactamases that commonly cause resistance to penicillins, allowing the piperacillin component to destroy susceptible bacteria. With the addition of dextrose, the premixed composition is physiologically isosmotic.

Abstract: The present invention provides a method of using a medical tubing with a pump for administering measured amounts of a beneficial fluid over time to a patient comprising the steps of providing a tubing having a first layer selected from the group consisting of ethylene homopolymers and ethylene copolymers, wherein the copolymers of ethylene are an ethylene monomer copolymerized with at least one monomer selected from the group consisting of lower alkyl olefins, lower alkyl esters of a carboxylic acid, and lower alkene esters of a carboxylic acid, the lower alkyl and lower alkene having from 3 to 18 carbons, the tubing having been exposed to a sterilization dosage of radiation of from about 15 to about 45 kGys; and pumping fluid through the tubing with the pump.

Abstract: The present invention provides a container for holding medical solutions, wherein the container comprises a fluid-tight chamber, the chamber having opposing first and second edges and opposing first and second surfaces, and a flap extending from an edge of the chamber and being hingedly connected to the chamber.

Abstract: A multiple layer structure comprising a skin layer composed of a polypropylene copolymer with styrene ethylene-butene styrene block copolymer within a range of 0-20% by weight skin layer, and, a radio frequency (“RF”) susceptible layer adhered to the skin layer. The RF layer has a first component of a propylene based polymer, a second component of a nonpropylene polyolefin, a third component of a radio frequency susceptible polymer, and a fourth component of a polymeric compatibilizing agent.

Abstract: The present invention provides a method of connecting a reconstitution device to a drug container having a top and a closure. The method includes the steps of:providing a reconstitution device having first and second ends, the second end having a receiving chamber dimensioned to receive the top of the container for fixedly attaching the device to the container, the device having a central channel housing a piercing member, the device further having first and second sleeve members capable of sliding axially with respect to one another from an inactivated position where the piercing member is outside the receiving chamber to an activated position where a portion of the piercing member is positioned inside the receiving chamber; andinserting the top of the container into the receiving chamber of the device and fixedly attaching the container therein when the device is in the inactivated position.

Abstract: The present invention provides a method for fabricating flexible medical tubings comprising the steps of providing a tubing of a polymer material, the tubing having a longitudinal axis and an initial diameter, orienting the tubing along the longitudinal axis of the tubing to reduce the diameter of the tubing to define a oriented diameter, and applying heat to the oriented tubing to heat set the tubing to maintain dimensional stability of the tubing over a temperature to which the tubing will normally be exposed.

Abstract: A connector device is disclosed for establishing fluid communication between a diluent container having sidewalls and a drug vial. The connector has a piercing member having a first end and a second end and a central fluid pathway. The piercing member is mounted to the liquid container and has fluid accessing portions hermetically sealed from an outside environment. A vial receiving chamber is associated with the piercing member and is dimensioned to connect to the vial. The vial may be selectively attached to the device without piercing the closure of the vial and without breaching the hermetic seal of the fluid accessing portions of the piercing member. Means are provided for connecting the vial receiving chamber to the liquid container.

Abstract: The present invention provides a connector device for establishing fluid communication between a first container and a second container. The device has a first sleeve member having a first and a second end, the first sleeve member having at the first end a first attaching member adapted to attach to the first container. The device further has a second sleeve member having a first end and a second end, the second sleeve member being associated with the first sleeve member and movable with respect thereto from an inactivated position to an activated position, the second sleeve member having at the second end a second attaching member adapted to attach the second sleeve member to the second container. First and second piercing members project from one of the first and second sleeve members for providing a fluid flow path from the first container to the second container, and the first and second piercing members are independently hermetically sealed.

Abstract: The present invention provides a connector device for establishing fluid communication between a first container and a second container. The device has a first sleeve member having a first end and a second end, the first sleeve member having at the first end a first attaching member adapted to attach to the first container; and a second sleeve member having a first end and a second end, the second sleeve member being associated with the first sleeve member and movable axially with respect thereto from an inactivated position to an activated position. A second attaching member is provided on the second end of the second sleeve and adapted to fixedly attach the second sleeve member to the second container. First and second piercing members are also provided projecting from one of the first and second sleeve members for providing a fluid flow path from the first container to the second container.