Abstract: A self-contained rehydratable microtiter type device is disclosed in which concentrations of suitable agents are predeposited and dried in growth wells and are then rehydrated with aliquot amounts of the inoculum to be tested. The apparatus and system permit the detection, identification and grouping of urinary tract pathogens.
Abstract: Analogues of prostaglandins A, E, and F in which the C.sub.13 -C.sub.20 chain of the natural prostaglandins is replaced by a cycloalkenyl or a hydroxycycloalkenyl moiety such that vinylene radical and the hydroxyl group of the ring respectively retain their natural sequential positions at C.sub.13 -C.sub.14 and C.sub.15, inhibit aggregation of platelets in vitro and exhibit useful cardiovascular activity in vivo.
Type:
Grant
Filed:
October 20, 1975
Date of Patent:
January 3, 1978
Assignee:
Miles Laboratories, Inc.
Inventors:
Warren Dexter Woessner, William Gerard Biddlecom, Henry Clifford Arndt, George Peter Peruzzotti, Charles John Sih
Abstract: Compounds having the generic structure, ##STR1## and their nontoxic, pharmacologically acceptable salts are useful in the chemotherapy of arrhythmias in individuals for whom such therapy is indicated. In the preceding structural formula: R.sup.1 is a 2-pyridyl, 3-pyridyl, or 4-pyridyl radical; n is an integer of the set 1-3; and R.sup.2 is a hydrogen atom, a hydroxyl, or an equivalent alkoxyl group having from 1 to 3 carbon atoms.
Type:
Grant
Filed:
October 4, 1976
Date of Patent:
December 6, 1977
Assignee:
Miles Laboratories, Inc.
Inventors:
Herbert John Havera, Wallace Glenn Strycker
Abstract: An alpha-amylase enzyme having optimum pH activity under alkaline conditions is produced from Bacillus species NRRL-3881. The enzyme is stable in the presence of chelating agents and is useful in producing maltose-containing products.
Type:
Grant
Filed:
March 12, 1971
Date of Patent:
December 6, 1977
Assignee:
Miles Laboratories, Inc.
Inventors:
Ernest Wendell Boyer, Morton Blakeman Ingle
Abstract: A test device and method are provided for determining the hemoglobin content of blood. The test device comprises a substantially opaque light reflecting matrix having a refractive index significantly different from the refractive index of blood. In use, a test sample of blood is contacted with the matrix of said test device and the light reflectance therefrom is measured as an indication of the quantitative amount of hemoglobin present in said sample.