Abstract: Described is a bioprocess for the high-yield production of food flavor-acceptable jasmonic acid and methyl jasmonate, as well as a novel jasmonic acid isomer produced thereby and organoleptic uses thereof. The process yields at least 5% of the “cis” isomer defined according the structure:
(wherein R is hydrogen or methyl) or at least 5% of the “cis” isomer defined according to the structure:
(wherein R is hydrogen or methyl). Compositions containing at least 98% of the isomer having the structure:
with an optical rotation (&agr;D20) of +58° are novel. Compositions containing at least 98% of the isomer having the structure:
with an optical rotation (&agr;D20) of +58° are also novel.
Type:
Grant
Filed:
August 22, 2001
Date of Patent:
October 1, 2002
Assignee:
International Flavors & Fragrances Inc.
Inventors:
Mohamad I. Farbood, Robert W. Blocker, Lynda B. McLean, Mark A. Sprecker, Michael P. McLean, Nicolas Kossiakoff, Augustine Yonghwi Kim, Myrna Hagedorn
Abstract: The invention relates to the manufacture of amide compounds provided through the reaction of nitrile compounds and a sulfate compound to form the related amide compound. In a preferred embodiment a diol or a triol is employed as a solvent, thereby increasing the yield of the product.
Abstract: Described is a fragrance control release system which is an emulsifier-free, single phase, nonporous, continuous, permeable polymeric film having a substantially uniform thickness of from about 1 up to about 150 microns, having entrapped and dissolved therein molecules of at least one fragrance substance capable of evolving from said film into the environment proximate said film by means of molecular diffusion at a permeation rate of from about 1×10−7 up to about 0.1 mg-mm/cm2-min in a sustained and controlled release manner. Also described is a process for using the aforementioned system for imparting a fragrance into the environment above the unobstructed outer surface of the aforementioned polymer film which is coated on the surface of a solid or semi-solid support, e.g., a solid surface or human epidermis.
Type:
Grant
Filed:
February 2, 2000
Date of Patent:
July 30, 2002
Assignee:
International Flavors & Fragrances Inc.
Inventors:
Adi Shefer, Shmuel David Shefer, John M. Teffenhart
Abstract: Flavor active proteins and methods for their manufacture and use are provided. The proteins are modified versions of the thaumatin and monellin proteins. Also provided are the cDNA sequences encoding these modified proteins.
Type:
Grant
Filed:
May 6, 1999
Date of Patent:
July 16, 2002
Assignee:
International Flavors & Fragrances Inc.
Inventors:
Paul L. Bolen, Paul L. Cihak, Lewis G. Scharpf, Jr., Kevin P. Miller, Nicolas Kossiakoff, Regina D. Hawn
Abstract: The present invention provides a container which provides a measured dosage of the contents of the container when pressure is applied to the top of the container. When not in use, the container additionally contains a locking means such that the contents of the container cannot be dispensed without repositioning the locking means to the open position.
Abstract: Described is a process and compositions for counteracting human sweat malodor. The compositions containing at least 10 weight percent of either 3,7-dimethyl-2,6-nonadienenitrile or 3,7-dimethyl-2,6-octadienenitrile. Additional ingredients may be added including napthyl methyl ether, methyl beta-naphthyl ketone, benzyl acetone, methanoinden propionates, methyl ionone, tetramethylnaphtho furan, ethylene glycol cyclic ester of dodecanedioic acid, 1-cyclohexadecen-6-one, 1-cycliheptadecen- 10-one, and corn mint oil. These compositions are applied to either fabric or a defined surface area of the human epidermis.
Type:
Grant
Filed:
June 23, 2000
Date of Patent:
April 30, 2002
Assignee:
International Flavors & Fragrances Inc.
Inventors:
Francisco Antonio Marano, Lisa T. Schreck, Mary E. Gordon, Jan Tijmen Van Elst, Kathleen Flannelly, Charles E. J. Beck
Abstract: The present invention provides kPGE and derivative polypeptides which are capable of being produced by genetic recombination and used to produce EMCs. This invention further provides nucleic acid sequences encoding kPGE and derivative polypeptides which can be used to create recombinant host cells that express kPGE and derivative polypeptides. A further subject of the present of invention is a fusion polypeptide called polyHis-enterokinase which increases expression of esterases and lipases when fused to the N-terminal of the esterase or lipase. This invention also provides a method for treating animals with an esterase or lipase deficiency by administering rkPGE to the animal in a therapeutically effective amount.
Type:
Grant
Filed:
November 5, 1998
Date of Patent:
April 23, 2002
Assignee:
International Flavors & Fragrances Inc.
Inventors:
Paul L. Bolen, Paul L. Cihak, Lewis G. Scharpf, Jr.
Abstract: Odor-inhibiting materials comprising litter containing an odor-inhibiting quantity of western juniper. The litter materials of the present invention are advantageous in that they can be used as animal bedding and the like to mask or prevent the formation of undesirable odors in animal laboratories, pet shops, litter boxes, kennels and the like.
Type:
Grant
Filed:
October 23, 2000
Date of Patent:
April 16, 2002
Assignee:
International Flavors & Fragrances Inc.
Inventors:
Richard M. Boden, Guillermo H. Fernandez
Abstract: Described are flavor composition, flavor component, perfume composition and perfume component-containing microparticles which are particulate matrices composed of:
(a) an olfactorily active component (e.g., perfume component);
(b) silica; and
(c) a saccharide composition which is a mixture of mannitol and maltose.
The microparticles are useful in augmenting, enhancing and/or imparting aroma and/or taste (over relatively long periods of time in a controllably releasable manner) to perfume compositions, perfumed articles (e.g., deodorancy and antiperspirant sticks), foodstuffs, chewing gums, beverages and the like. Also described is a process for preparing the above-mentioned microparticles using, in sequence, (1) adsorption of the olfactorily active material onto silica followed by (2) a blending/extrusion step followed by (3) at least one particularization step.
Type:
Grant
Filed:
May 14, 2001
Date of Patent:
April 9, 2002
Assignee:
International Flavors & Fragrances Inc.
Inventors:
Wen Chin Lou, Keith J. McDermott, Shmuel David Shefer, Adi Shefer, John M. Teffenhart, Chee-Teck Tan, Jerome I. Lindauer, Leslie C. Smith
Abstract: Described are oral sensory perception-affecting compositions containing dimethyl sulfoxide, complexes thereof and salts thereof, specifically:
(i) dimethyl sulfoxide; and
(ii) a second compound or group of compounds:
(a) containing at least one menthyl moiety; and/or
(b) containing at least one vanillyl moiety; and/or
(c) containing at least one carboxamide moiety
when the weight ratio of “second compound(s)”:dimethyl sulfoxide, is in the range of from about 1,000:1 down to about 3:10 and food grade acceptable salts thereof. Also described are oral sensory perception-affecting (e.g., “coolant”)-imparting consumable articles (e.g., mouthwashes and the like) comprising a consumable article base and at least one of the aforementioned oral sensory perception-affecting compositions. Also described are complexes of (i) dimethyl sulfoxide and (ii) at least one of the aforementioned second compounds or group(s) of compounds.
Type:
Grant
Filed:
November 9, 2000
Date of Patent:
April 2, 2002
Assignee:
International Flavors & Fragrances Inc.
Inventors:
Brian T. Grainger, Robert J. Kleinhenz, Gary W. Christensen
Abstract: The present invention is directed to indanyl derivatives and the use of the indanyl derivatives in creating fragrances, and scents in items such as perfumes, colognes and personal care products.
Type:
Grant
Filed:
September 6, 2001
Date of Patent:
March 26, 2002
Assignee:
International Flavors & Fragrances Inc.
Inventors:
Mark A. Sprecker, Richard A. Weiss, Robert P. Belko, Ellen Ann Molner
Abstract: The present invention is directed to indanyl derivatives and the use of the indanyl derivatives in creating fragrances, and scents in items such as perfumes colognes and personal care products.
Type:
Grant
Filed:
January 26, 2001
Date of Patent:
January 29, 2002
Assignee:
International Flavors & Fragrances Inc.
Inventors:
Mark A. Sprecker, Richard A. Weiss, Robert P. Belko, Ellen Ann Molner
Abstract: The present invention is directed to 3-hexenyl-2-methylallyl ether and its use in creating perfumes and scents in such items as perfumes, colognes, toilet water and personal care products.
Type:
Grant
Filed:
September 6, 2000
Date of Patent:
January 22, 2002
Assignee:
International Flavors & Fragrances Inc.
Inventors:
Anubhav P. S. Narula, Edward Arruda, James Joseph Koestler, Ellen Ann Molner
Abstract: Described is a water-soluble solid-phase ironing aid-freshening composition for use in forming controllably dimensioned tablets, which have controlled weights and densities and which are conveniently added to the water-containing steam chamber of a steam iron. The use of the tablets produced from the composition enables textiles which are ironed to be freshened and de-wrinkled. The composition includes (i) a support substance; (ii) a tablet binder substance; and (iii) a fragrance composition and, optionally, a silicone resin, a chelating agent and/or a surfactant.
Type:
Grant
Filed:
December 21, 1999
Date of Patent:
December 11, 2001
Assignee:
International Flavors & Fragrances Inc.
Inventors:
Michael John Robert White, Andrew John Crossman, David Neil Ellison
Abstract: The present invention provides a fragrant article that delivers fragrance over a period of time by an article comprising a polymer matrix, a fragrance and a decorative object. The decorative object is contained within a polymer matrix and in a preferred embodiment is the similar to the fragrance that is being released. The article is particularly well suited to be used as a room freshener, which because of its attractive appearance does not need to be hidden.
Type:
Grant
Filed:
August 2, 2000
Date of Patent:
October 30, 2001
Assignee:
International Flavors & Fragrances Inc.
Inventors:
Jerome I. Lindauer, Robert Reid, Lynn Iarossi, Andrea Lynn Meyer
Abstract: Described are &agr;-oxygen-substituted cyclohexane propionitriles having the structure:
wherein R20 and R21 are the same or different C1-C3 lower alkoxy; or wherein R20 is hydrogen and R21 is hydroxy, C1-C3 lower alkoxy or C1-C3 lower acyloxy; and wherein R1, R2, R3, R4, R5, R6 and R7 are the same or different hydrogen or C1-C4 lower alkyl, and uses thereof for their organoleptic properties in augmenting or enhancing or imparting aromas in or to perfume compositions, colognes, microporous polymers or perfumed articles including solid or liquid anionic, cationic, nonionic or zwitterionic detergents, fabric softener compositions, fabric softener articles, hair care compositions and the like.
Type:
Grant
Filed:
March 2, 2000
Date of Patent:
October 30, 2001
Assignee:
International Flavors & Fragrances Inc.
Inventors:
Mark A. Sprecker, Richard A. Weiss, Marie R. Hanna, Charles E. J. Beck
Abstract: The present invention is directed to a novel dioxin compound and the use of the novel compound in creating fragrances, and scents in items such as perfumes, colognes and personal care products.
Type:
Grant
Filed:
February 23, 2001
Date of Patent:
October 16, 2001
Assignee:
International Flavors & Fragrances Inc.
Inventors:
Robert P. Belko, Mark A. Sprecker, Charles E. J. Beck
Abstract: The invention relates to the manufacture of amide compounds provided through the reaction of nitrile compounds and a sulfate compound to form the related amide compound. In a preferred embodiment a diol or a triol is employed as a solvent, thereby increasing the yield of the product.
Abstract: Described is a fragrance control release system which is an emulsifier-free, single phase, nonporous, continuous, permeable polymeric film having a substantially uniform thickness of from about 1 up to about 150 microns, having entrapped and dissolved therein molecules of at least one fragrance substance capable of evolving from said film into the environment proximate said film by means of molecular diffusion at a permeation rate of from about 1×10−7 up to about 0.1 mg-mm/cm2-min in a sustained and controlled release manner. Also described is a process for using the aforementioned system for imparting a fragrance into the environment above the unobstructed outer surface of the aforementioned polymer film which is coated on the surface of a solid or semi-solid support, e.g., a woven or non-woven fabric substrate; or a solid surface or human epidermis.
Type:
Grant
Filed:
July 21, 1999
Date of Patent:
September 18, 2001
Assignee:
International Flavors & Fragrances Inc.
Inventors:
Adi Shefer, Shmuel David Shefer, Michael John Robert White