Patents Represented by Attorney Joseph F. Leightner
  • Patent number: 6271194
    Abstract: Described are optical isomers of (+) &dgr;-decalactone and (+) &dgr;-dodecalactone which impart, augment and/or enhance the aroma and/or taste of consumable materials including foodstuffs, chewing gums, toothpastes, beverages, fragrance compositions, colognes and perfumed articles such as solid or liquid anionic, cationic, nonionic or zwitterionic detergents, fabric softeners and hair preparations. The optical isomers are produced by means of a two-phase, environmentally friendly fermentation process for producing high yields of (+) &dgr;-decalactone and (+) &dgr;-dodecalactone from the corresponding unsaturated starting materials. The (+) &dgr;-decalactone substantially has the structure: with a very minor amount of isomer having the structure: and an optical rotation of +53.64° ((&agr;D20=+53·64° ) ). The (+) &dgr;-decalactone, which is the subject of the invention, has an enantiomeric excess percent of 95.
    Type: Grant
    Filed: December 21, 1999
    Date of Patent: August 7, 2001
    Assignee: International Flavors & Fragrances Inc.
    Inventors: Mohamad I. Farbood, Laura E. Kizer, James A. Morris, Gail Harris, Lynda B. McLean, Robert W. Blocker
  • Patent number: 6271193
    Abstract: Described are carbon-containing functional groups substituted 4,5,6,7-tetrahydro-polyalkylated-4-indanes, isomers thereof, process for processes for preparing same, and uses thereof. The 4,5,6,7-tetrahydro-polyalkylated-4-indanes have the generic structure: Wherein G and R1-5 are as defined in the specification. The aforementioned materials have fragrance properties or are intermediates for materials which have fragrance properties. Also described are processes for producing the aforementioned substances.
    Type: Grant
    Filed: October 11, 2000
    Date of Patent: August 7, 2001
    Assignee: International Flavors & Fragrances Inc.
    Inventors: Mark A. Sprecker, Richard A. Weiss, Anthony T. Levorse, Jr., Howard H. Heinsohn, Jr., Charles E. J. Beck, Marie R. Hanna
  • Patent number: 6255356
    Abstract: Described is a method for inhibiting from feeding German cockroaches (Blattella germanica) from a surface or volume inhabited by said Blattella germanica consisting of the step of applying to said surface or said volume a Blattella germanica-anti-feedant quantity and concentration of a geraniol-containing mixture comprising: (i) from about 0 up to about 20% by weight of nerol; (ii) from about 20 up to about 40% by weight of citronellol; and (iii) from about 50 up to about 70% by weight of geraniol, which geraniol-containing mixture is defined according to specific GLC profiles set forth in FIGS. 4 and 5, described in the disclosure. Also described are compositions of matter defined according to the geraniol-containing compositions of FIGS. 4 and 5 which act as anti-feedants against the German cockroach species set forth above.
    Type: Grant
    Filed: March 30, 2000
    Date of Patent: July 3, 2001
    Assignees: International Flavors & Fragrances Inc., The University of Florida
    Inventor: Jerry F. Butler
  • Patent number: 6245376
    Abstract: Described are processes for removing the bitter aftertaste and enhancing the sweetness of a cola beverage having dissolved therein a sweetening quantity and concentration of aspartame, which causes a bitter aftertaste on subsequent ingestion of the cola beverage. The process consists of adding to the beverage from about 1 up to about 20 ppb of damascenone and at least one of the alcohols: cis-3-hexenol; 1-octen-3-ol; or &bgr;-phenylethyl alcohol. In the alternative, the process consists of adding to the cola beverage from about 1 up to about 20 ppb of &bgr;-homocyclocitral and at least one of the oxo compounds, cis-3-hexenol, acetophenone, or the pineapple compound. In the alternative, the process consists of adding to the cola beverage from about 1 up to about 20 ppb of a mixture of cis-3-hexenol and the pineapple compound.
    Type: Grant
    Filed: November 17, 1999
    Date of Patent: June 12, 2001
    Assignee: International Flavors & Fragrances Inc.
    Inventors: Alan Owen Pittet, Kevin P. Miller, Marvin Schulman, Ranya Muralidhara, William J. Kinlin, Carlos Ramirez, Michael F. Javes
  • Patent number: 6235274
    Abstract: Described are flavor composition, flavor component, perfume composition and perfume component-containing microparticles which are particulate matrices composed of: (a) an olfactorily active component (e.g., perfume component); (b) silica; and (c) a saccharide composition which is a mixture of mannitol and maltose. The microparticles are useful in augmenting, enhancing and/or imparting aroma and/or taste (over relatively long periods of time in a controllably releasable manner) to perfume compositions, perfumed articles (e.g., deodorancy and antiperspirant sticks), foodstuffs, chewing gums, beverages and the like. Also described is a process for preparing the above-mentioned microparticles using, in sequence, (1) adsorption of the olfactorily active material onto silica followed by (2) a blending/extrusion step followed by (3) at least one particularization step.
    Type: Grant
    Filed: December 21, 1999
    Date of Patent: May 22, 2001
    Assignee: International Flavors & Fragrances Inc.
    Inventors: Wen Chin Lou, Keith J. McDermott, Shmuel David Shefer, Adi Shefer, John M. Teffenhart, Chee-Teck Tan, Jerome I. Lindauer, Leslie C. Smith
  • Patent number: 6120801
    Abstract: A simulated capsule-like medicament comprising a subcoating of a mixture of a water-soluble, film-forming polymer, e.g. hydroxypropylmethyl cellulose and a hydrophobic plasticizer, e.g. castor oil, which promotes a smooth uniform and substantially bubble free outer coating, e.g. gelatin, for the capsule-like medicament; capsule-like medicaments which are slightly bowed in shape; and a process of making such medicaments.
    Type: Grant
    Filed: April 15, 1999
    Date of Patent: September 19, 2000
    Assignee: McNeil-PPC, Inc.
    Inventors: Kishor B. Parekh, Dennis C. Wieand, Jean B. Leasure
  • Patent number: 6110502
    Abstract: A method for preparing .beta.-sitosterol is disclosed which provides the sterol in a readily consumable form. The method includes the spray drying of the .beta.-sitosterol in a mixed micelle formulation. The product is provided in a convenient form that can be provided to food or drinks or incorporated into solid and suspension dosage forms.
    Type: Grant
    Filed: February 19, 1998
    Date of Patent: August 29, 2000
    Assignee: McNeil-PPC, Inc.
    Inventors: Brid Burruano, Richard D. Bruce, Michael R. Hoy
  • Patent number: 6057139
    Abstract: A preblend for making lactase tablets is prepared containing about 1-99% (preferably about 20-60%) by weight lactase and about 1-99% (preferably about 40-80%) by weight microcrystalline cellulose. Lactase used in the preblend may be in combination with up to about 4 parts (preferably about 0.5-2 parts) by weight cutting agent such as sugars, starches, cellulose, and inorganic salts for each part by weight lactase. About 0.5-4% by weight lubricant such as magnesium stearate may be present in the preblend. A preferred preblend contains about 9.6 weight percent lactase and about 90 weight percent microcrystalline cellulose. Another preferred preblend contains about 9.6 weight percent lactase, about 30.0 weight percent microcrystalline cellulose and about 59.4 weight percent mannitol. Each preblend may also contain magnesium stearate. A preferred lactase is from Aspergillus oryzae and the microcrystalline cellulose preferably has an average particle size of about 20-200 .mu.m.
    Type: Grant
    Filed: June 29, 1995
    Date of Patent: May 2, 2000
    Assignee: McNeil-PPC, Inc.
    Inventors: Sunanda R. Kulkarni, Robert T. McFadden, David H. Rogers, James T. Walter, Jr.
  • Patent number: 6054144
    Abstract: A method for preparing .beta.-sitosterol, oryzanol, esters of both of these compounds and related compounds are disclosed which provides the sterol in a readily consumable form. The method includes the spray drying of the .beta.-sitosterol in a mixed micelle formulation. The product is provided in a convenient form that can be provided to food or drinks or incorporated into solid and suspension dosage forms.
    Type: Grant
    Filed: November 4, 1998
    Date of Patent: April 25, 2000
    Assignee: McNeil-PPC, Inc.
    Inventors: Brid Burruano, Richard D. Bruce, Michael R. Hoy, John D. Higgins, III
  • Patent number: 6022551
    Abstract: A rapidly acting antimicrobial alcohol-containing composition and method of using the composition to disinfect surfaces, such as the hands is disclosed.
    Type: Grant
    Filed: January 20, 1998
    Date of Patent: February 8, 2000
    Assignee: Ethicon, Inc.
    Inventors: Hanuman B. Jampani, Jerry L. Newman
  • Patent number: 5997893
    Abstract: The present invention provides antimicrobial compositions containing high levels of alcohol, carbomer polymers and antimicrobial agents. The present invention provides stable, high viscosity antimicrobial formulations possessing cosmetic characteristics.
    Type: Grant
    Filed: January 20, 1998
    Date of Patent: December 7, 1999
    Assignee: Ethicon, Inc.
    Inventors: Hanuman B. Jampani, Jerry L. Newman, Anthony W. Newman
  • Patent number: 5972358
    Abstract: The present invention relates to a mixture of a silicone wax, a silicone fluid and two long chain lactate molecules which is effective in reducing the tacky feel of compositions. The present invention is suitable for use in creams, gels, lotions and salves that are applied to the skin.
    Type: Grant
    Filed: January 20, 1998
    Date of Patent: October 26, 1999
    Assignee: Ethicon, Inc.
    Inventors: Hanuman B. Jampani, Anthony W. Newman
  • Patent number: 5941861
    Abstract: A disposable panty shield comprising a thin, highly absorbent pad having a body-contacting surface, an absorbent layer, a liquid barrier, an adhesive layer, and a release layer to protect a positioning adhesive prior to use wherein the panty shield has been densified by fusing all pad layers together in a manner such that the interstitial space between the individual fibers in the densified areas is not sufficient to readily allow fluid to flow through, and the liquid barrier has a contoured surface. The adhesive layer is attached to the liquid barrier such that the adhesive follows the contour of the liquid barrier.
    Type: Grant
    Filed: June 23, 1997
    Date of Patent: August 24, 1999
    Assignee: McNeil-PPC, Inc.
    Inventor: Anthony C. Ng
  • Patent number: 5868846
    Abstract: A nozzle assembly is provided with a valve to enable the coating of low aspect ratio items such as tablets. In a preferred embodiment a valve is disclosed such that the vacuum forces acting on the surfaces of the valve are equal to the weight of the valve. This balancing of the weight of the valve and the vacuum forces allows gravity to be the primary motive force for actuation. The weight of the valve is used to detect a tablet, such that when a tablet is missing, the valve prevents any coating from being pulled into the nozzle.
    Type: Grant
    Filed: August 20, 1997
    Date of Patent: February 9, 1999
    Assignee: McNeil-PPC, Inc.
    Inventor: Harry S. Sowden
  • Patent number: 5817340
    Abstract: A solid oral dosage form for the treatment of gastrointestinal disorders comprising a therapeutically effective amount of a therapeutically effective amount of guanidinothiazole compound; and a therapeutically effective amount of an antacid wherein the pharmaceutical and an antacid are separated by a barrier which is substantially impermeable to an antacid.
    Type: Grant
    Filed: November 25, 1996
    Date of Patent: October 6, 1998
    Assignee: McNeil-PPC, Inc.
    Inventors: Edward John Roche, Susan Decoteau, Eleanor Freeman
  • Patent number: D415961
    Type: Grant
    Filed: November 2, 1998
    Date of Patent: November 2, 1999
    Assignee: McNeil-PPC, Inc.
    Inventors: Michael Faughey, Daniel A. Backich, M. Simon Freed, Brian J. Brozell
  • Patent number: D416195
    Type: Grant
    Filed: November 2, 1998
    Date of Patent: November 9, 1999
    Assignee: McNeil-PPC, Inc.
    Inventors: Michael Faughey, Daniel A. Backich, M. Simon Freed, Brian J. Brozell
  • Patent number: D416793
    Type: Grant
    Filed: November 2, 1998
    Date of Patent: November 23, 1999
    Assignee: McNeil-PPC, Inc.
    Inventors: Michael Faughey, Daniel A. Backich, M. Simon Freed, Brian J. Brozell
  • Patent number: D419061
    Type: Grant
    Filed: March 19, 1999
    Date of Patent: January 18, 2000
    Assignee: McNeil-PPC, Inc.
    Inventors: Robert Croft, James Warner, Robert Boyce, Neil Enciso
  • Patent number: D427914
    Type: Grant
    Filed: March 20, 1999
    Date of Patent: July 11, 2000
    Assignee: McNeil-PPC, Inc.
    Inventors: Robert Croft, James Warner, Robert Boyce, Neil Enciso