Abstract: The invention relates to a system capable of electronically matching transportation reservations with existing, new, or potential reservations, so that the orders can be combined, the reservation shared between requesting parties, utilization and management of transportation provider inventory and costs can be optimized, and savings opportunities for customers may be provided. Costs may also be divided proportionally based on a combination of distance and/or time traveled, or other cost accrual methods per riding party, and split/billed electronically via the reservation system. The system can operate as a standalone reservation repository or in concert with one or many existing reservation providers.

Abstract: The biological activity of nucleic acid ligand is regulated (i.e. enhanced or inhibited) in vivo to produce a desired biological effect. This is accomplished through the administration of a modulator, or regulator, that changes the binding of the nucleic acid ligand for its target or that degrades or otherwise cleaves, metabolizes or breaks down the nucleic acid ligand while the ligand is still exerting its effect. Modulators of the present invention can be administered in real time as needed based on various factors, including the progress of the patient, as well as the physician's discretion in how to achieve optimal therapy. Thus, this invention provides for the first time a regulatable therapeutic regime in the course of nucleic acid ligand therapy.

Abstract: A sensory aroma glass is disclosed. According to one embodiment, an apparatus comprises a fluid barrier; and a fluid container designed for containing a fluid. The fluid barrier is in contact with the rim or internal or external sidewall of the fluid container. The fluid barrier extends into the fluid container. The fluid barrier has an opening that allows aroma of the fluid to escape from the fluid container without allowing the fluid to escape from the fluid container.

Abstract: Efficiency of a hydraulically driven system is evaluated by monitoring the change in ratio of output torque to input hydraulic pressure. The hydraulic pressure data is received from a hydraulic sensor. The torque data is received from a load cell receiving a force transmitted to it by a back-up wrench. Filters are applied to the data to obtain peak levels of torque and hydraulic pressure. A ratio is generated for each process associated with a rod or other elongated member based on peak torque and hydraulic pressure levels achieved during the process. The ratio is stored and compared to historical ratios to determine if the ratio has changed more than a predetermined amount over time. A similar evaluation can be achieved by comparing speed generated on the elongated member by the hydraulically driven system to the current level controlling the flow of hydraulic fluid to the hydraulically driven system.

Abstract: The present invention is directed to methods for controlling the operations of a well service rig at a well site by evaluating load sensor data obtained from sensors on or associated with the well service rig. A rig load data chart can be reviewed and an average rig load can be determined for each pull of tubing or rods from a well. The average rig load can be used to calculate and set a rig overload level. If the rig load sensor reads a rig load at or above the rig overload level, the clutch for the hoist can be disengaged and the brake applied to prevent the load from either damaging the rig or breaking off the tubing or rods in the well. In addition, the rig load can be evaluated to determine when the limit the block speed when pulling rods or tubing.

Abstract: The connector between the patient electrode pads and the base unit of an automatic external defibrillator (AED) system can be formed by capturing a printed circuit board (PCB) within a connector housing. The PCB can have conductive metal traces that serve as the contact points between the wires from the patient electrodes and the electronics within the AED base unit. The PCB in combination with the conductive metal traces can be shaped similar to a conventional two-prong or two-blade connector. Employing such a PCB-based connector may result in AED pads which are less complex and less costly to manufacture. The PCB can also support a configuration circuit that is positioned between the conductive metal traces and that allows the AED to read and store information about the attached pads. For example, the AED can use this data storage feature to check the expiration date of the pads.

Abstract: Systems and methods for maximizing energy recovery from a subterranean formation are herein disclosed. According to one embodiment, a selected subterranean open-hole interval is isolated and at least one fracture is stimulated in the isolated subterranean open-hole interval.

Abstract: A lighting system comprises a row of light emitting diodes (“LEDs”) receiving electricity and producing light and heat. The row of LEDs can be located in a channel or a groove of a piece of material, such as an aluminum extrusion or a bent piece of metal. The channel can have an optically reflective lining, for example, providing either diffuse or specular reflection. Accordingly, the channel can reflect light emitted by the LEDs. The piece of material can also include a heat sink for transferring heat from the LEDs to air via convection or air flow. The heat sink can comprise fins or protrusions that facilitate convection.

Abstract: An application software generator automatically generates an application software unit. The application software generator includes an application composer that combines components extracted from a component repository with an application framework to generate the application software unit. Each component in the component repository includes a component shell, a component interface and a component core. The application framework includes configurable parameters that determine how the application software unit is generated and operates. The configurable parameters can be entered by a user using a graphical user interface. The user can be assisted using a wizard format. The application framework also provides connectivity between components so that they can pass messages to one another. The connectivity can be, for example, by a message bus or event registry and event dispatch. Components themselves can be automatically generated using the application software generator.

Abstract: Grouping, categorizing, and profiling pharmaceutical claims data to assist health care managers is described. In aspects, a method is described including receiving pharmacy claims data records, validating each of the claims data records for a valid drug code, establishing a number of validated pharmacy claims data records received for each drug identified, grouping the validated pharmacy claims data records to one or more pharmacy episodes, categorizing each pharmacy episode, and storing the validated pharmacy claims data records and associated pharmacy episodes for monitoring usage of prescription drugs. In various embodiments, a pharmacy episode group is a pharmacologically homogenous grouping of drugs with the same therapeutic ingredients used by a patient once or over an extended period of time, and pharmacy episodes are categorized based on algorithms linking the pattern of a physician's recommended use and the patient's pattern of compliance.

Abstract: A database may be virtually partitioned into virtual partitions. The virtual partitions are mapped to physical databases of a database. Data records added to the database are each assigned to a virtual partition and stored in the physical database mapped to the assigned virtual partition. The identifier generated for a data record includes an identifier of the assigned virtual partition. When additional databases are created, virtual partitions are remapped to the larger space of physical databases.

Abstract: Disclosed are compounds based on C- and D-ring modifications of triptolide and hydroxylated triptolide, for use in therapy, such as antiproliferative, anticancer, and immunosuppressive therapy.

Abstract: The invention relates to a connecting element for the mechanical connection of at least two components, in particular two components of a motor vehicle door, with a bearing collar for bearing against a first component, with a crossbar that has bearing flanks for bearing against a second component and for clamping the latter against the first component in a rotated final assembly position, and with a shaft section, which bears the crossbar, for rotatably passing through corresponding openings in the components. In this case, a means is provided for fastening to the first component in a defined preassembly position. Furthermore, the invention relates to a corresponding connecting arrangement comprising at least two components each having an aperture, and a connecting element of this type, with the connecting element being held on the first component in a preassembly position.

Abstract: Training defense of a computer network. The system includes an enterprise asset subsystem to be defended. The enterprise asset subsystem runs operating system, support services, and application programs. The system also includes a neutral subsystem that is in communication with the enterprise asset subsystem and is used to set up and run at least one exercise scenario, and score performance of enterprise asset defenders in defending the system against exploits. Exploits are launched by an exploitation subsystem communication with the enterprise asset subsystem.